A physiologically based pharmacokinetic model of organophosphate dermal absorption

journal article published in 2006

A physiologically based pharmacokinetic model of organophosphate dermal absorption is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/TOXSCI/KFJ014
P8608Fatcat IDrelease_ydgh7b5fwjghzmwb2x5mwdvtt4
P2880NIOSHTIC-2 ID20029237
P698PubMed publication ID16221965
P5875ResearchGate publication ID7544238

P2093author name stringD. van der Merwe
R Gehring
J E Riviere
N A Monteiro-Riviere
J D Brooks
R E Baynes
P2860cites workÜber die von der molekularkinetischen Theorie der Wärme geforderte Bewegung von in ruhenden Flüssigkeiten suspendierten TeilchenQ8079432
Is the permeability coefficient Kp a reliable tool in percutaneous absorption studies?Q45207730
In vitro permeability and binding of hydrocarbons in pig ear and human abdominal skinQ45711020
A predictive algorithm for skin permeability: the effects of molecular size and hydrogen bond activityQ46059964
Novel cyclosporin derivatives featuring enhanced skin penetration despite increased molecular weightQ46421159
In vitro dermal absorption of pesticides: VI. In vivo and in vitro comparison of the organochlorine insecticide DDT in rat, guinea pig, pig, human and tissue-cultured skinQ46718225
PENETRATION OF LOW-MOLECULAR-WEIGHT ALCOHOLS INTO SKIN. I. EFFECT OF CONCENTRATION OF ALCOHOL AND TYPE OF VEHICLE.Q47419669
Evaluation of solute permeation through the stratum corneum: lateral bilayer diffusion as the primary transport mechanism.Q52254833
The role of protein and lipid domains in the uptake of solutes by human stratum corneumQ68064219
The isolated perfused porcine skin flap (IPPSF). I. A novel in vitro model for percutaneous absorption and cutaneous toxicology studiesQ69662173
Methods for in vitro percutaneous absorption studies. I. Comparison with in vivo resultsQ70324222
Transdermal delivery of dideoxynucleoside-type anti-HIV drugs. 2. The effect of vehicle and enhancer on skin permeationQ71198082
Mutual hairless rat skin permeation-enhancing effect of ethanol/water system and oleic acidQ71787773
Dermal exposure assessment of polycyclic aromatic hydrocarbons: in vitro percutaneous penetration from lubricating oilQ73258029
The permeability of skin to some non-electrolytesQ74163526
In vivo skin absorption and distribution of the nerve agent VX (O-ethyl-S-[2(diisopropylamino)ethyl] methylphosphonothioate) in the domestic white pigQ81107411
Methods for in vitro percutaneous absorption studies V: Permeation through damaged skinQ93661603
Effect of vehicles and sodium lauryl sulphate on xenobiotic permeability and stratum corneum partitioning in porcine skinQ23912054
Steady‐State Flux and Lag Time in the Stratum Corneum Lipid Pathway: Results from Finite Element ModelsQ23913348
Predicting skin permeability from complex chemical mixturesQ23914920
Rapid hop diffusion of a G-protein-coupled receptor in the plasma membrane as revealed by single-molecule techniquesQ24538587
Mathematical modeling in environmental healthQ24817117
Zur kinetischen Theorie der Brownschen Molekularbewegung und der SuspensionenQ28109717
Diffusion theory in biology: a relic of mechanistic materialism.Q30328902
Visualization of the lipid barrier and measurement of lipid pathlength in human stratum corneumQ30777010
Prediction of percutaneous absorption from physicochemical data: a model based on data of in vitro experimentsQ32035782
Pharmacokinetic models of dermal absorption.Q34105294
Structure of the skin barrier and its modulation by vesicular formulationsQ35017707
Framework for evaluation of physiologically-based pharmacokinetic models for use in safety or risk assessmentQ36014859
Percutaneous absorption: in vivo experimentsQ39243884
Permeability of the skinQ40002436
Modelling skin permeability in risk assessment--the futureQ40517594
Quantitative structure-permeation relationships (QSPeRs) to predict skin permeation: a critical evaluation.Q40529332
Comparison of human skin or epidermis models with human and animal skin in in-vitro percutaneous absorptionQ43543116
Toxicokinetics and Metabolism ofN-[14C]N-Methyl-2-Pyrrolidone in Male Sprague-Dawley Rats: in Vivo and in Vitro Percutaneous AbsorptionQ44403645
Percutaneous absorption of radioactive strontium chloride Sr 89 (89SrCl2). A comparison with 11 other metal compoundsQ44590164
Percutaneous absorption of parathion in vitro in porcine skin: Effects of dose, temperature, humidity, and perfusate composition on absorptive fluxQ44857504
A physiologically relevant pharmacokinetic model of xenobiotic percutaneous absorption utilizing the isolated perfused porcine skin flapQ44859273
Comparative studies on the effects of water, ethanol and water/ethanol mixtures on chemical partitioning into porcine stratum corneum and silastic membraneQ44861351
Percutaneous absorption, dermatopharmacokinetics and related bio-transformation studies of carbaryl, lindane, malathion, and parathion in isolated perfused porcine skinQ44862449
The effect of penetration enhancers on drug delivery through skin: a QSAR study.Q45040619
P6195funding schemegrantQ230788
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectpesticideQ131656
toxinQ184651
solventQ146505
toxicityQ274160
pharmacokineticsQ323936
organophosphateQ411097
mixed exposuresQ32984844
P5008on focus list of Wikimedia projectWikimedia–NIOSH collaborationQ104416361
P304page(s)188-204
P12526performing organizationNorth Carolina State UniversityQ1132346
P577publication date2005-10-26
P1433published inToxicological SciencesQ2446966
P859sponsorNational Institute for Occupational Safety and HealthQ60346
P1476titleA physiologically based pharmacokinetic model of organophosphate dermal absorption
P478volume89

Reverse relations

cites work (P2860)
Q36129985Chronic pesticide exposure: Health effects among pesticide sprayers in Southern India
Q37694755Design and application of microfluidic systems for in vitro pharmacokinetic evaluation of drug candidates
Q23921295Development and application of quantitative methods for monitoring dermal and inhalation exposure to propiconazole
Q44471749In silico prediction of percutaneous absorption and disposition kinetics of chemicals
Q47154406Modern methodologies and tools for human hazard assessment of chemicals
Q38007558Nanocarrier-based topical drug delivery for the treatment of skin diseases
Q28294393Penetration of intact skin by quantum dots with diverse physicochemical properties
Q34401947Potential new therapeutic modality revealed through agent-based modeling of the neuromuscular junction and acetylcholinesterase inhibition
Q41535034Quantifying the efficacy of first aid treatments for burn injuries using mathematical modelling and in vivo porcine experiments.
Q44763351Quantitative structure-activity relationships for organophosphates binding to trypsin and chymotrypsin
Q23918022Toward a better understanding of pesticide dermal absorption: diffusion model analysis of parathion absorption in vitro and in vivo
Q34389851Towards a strategic approaches in alternative tests for pesticide safety
Q38832036[60]Fullerene-peptides: bio-nano conjugates with structural and chemical diversity

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