| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2001PNAS...98..130B |
| P356 | DOI | 10.1073/PNAS.98.1.130 |
| P8608 | Fatcat ID | release_4uxioodzevafnjxax5equtu6ba |
| P3181 | OpenCitations bibliographic resource ID | 2312774 |
| P932 | PMC publication ID | 14556 |
| P698 | PubMed publication ID | 11136250 |
| P5875 | ResearchGate publication ID | 12193240 |
| P50 | author | Mary-Claire King | Q437741 |
| Flossie Wong-Staal | Q3074353 | ||
| P2093 | author name string | Kruger M | |
| Welte K | |||
| Robbins JM | |||
| Barber JR | |||
| Beger C | |||
| Welch PJ | |||
| Pierce LN | |||
| Marcusson EG | |||
| Welcsh P | |||
| P2860 | cites work | BRCA1 expression is not directly responsive to estrogen | Q48055063 |
| Growth retardation and tumour inhibition by BRCA1. | Q48066075 | ||
| A somatic BRCA1 mutation in an ovarian tumour | Q48074726 | ||
| BRCA1 mutations in primary breast and ovarian carcinomas | Q48078473 | ||
| Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages. | Q52174703 | ||
| Regulation of BRCA1 expression by the Rb-E2F pathway. | Q53413911 | ||
| Somatic mutations in the BRCA1 gene in sporadic ovarian tumours. | Q54417578 | ||
| Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome | Q57266956 | ||
| Methylation of the BRCA1 gene in sporadic breast cancer | Q57390855 | ||
| Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression | Q72345882 | ||
| GA-binding protein alpha/beta is a critical regulator of the BRCA1 promoter | Q73694700 | ||
| Decreased BRCA1 expression levels may arrest the cell cycle through activation of p53 checkpoint in human sporadic breast tumors | Q74424356 | ||
| Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics | Q77340263 | ||
| Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach | Q22254630 | ||
| Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1 | Q24321914 | ||
| Molecular cloning of ID4, a novel dominant negative helix-loop-helix human gene on chromosome 6p21.3-p22 | Q24337069 | ||
| Id helix-loop-helix proteins inhibit nucleoprotein complex formation by the TCF ETS-domain transcription factors | Q24533584 | ||
| BRCA1-associated growth arrest is RB-dependent | Q24675010 | ||
| A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 | Q28115843 | ||
| Basic helix-loop-helix proteins can act at the E-box within the serum response element of the c-fos promoter to influence hormone-induced promoter activation in Sertoli cells | Q28143562 | ||
| The protein Id: a negative regulator of helix-loop-helix DNA binding proteins | Q28237471 | ||
| Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins | Q28294328 | ||
| Identification and validation of a gene involved in anchorage-independent cell growth control using a library of randomized hairpin ribozymes | Q28508476 | ||
| An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene | Q28512610 | ||
| MIDA1, a protein associated with Id, regulates cell growth | Q28584968 | ||
| Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1. | Q30714274 | ||
| Cleavage of highly structured viral RNA molecules by combinatorial libraries of hairpin ribozymes. The most effective ribozymes are not predicted by substrate selection rules | Q32030867 | ||
| Enhancer of splitD, a dominant mutation of Drosophila, and its use in the study of functional domains of a helix-loop-helix protein | Q33613008 | ||
| A novel pathway for mammary epithelial cell invasion induced by the helix-loop-helix protein Id-1. | Q33775175 | ||
| Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families | Q34321216 | ||
| The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein | Q34323413 | ||
| MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer | Q34453492 | ||
| Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas | Q34492521 | ||
| Hormone-dependent regulation of BRCA1 in human breast cancer cells. | Q34719862 | ||
| Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1 | Q36429077 | ||
| Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1. | Q36551976 | ||
| The helix-loop-helix protein Id inhibits differentiation of murine erythroleukemia cells | Q38310992 | ||
| The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells | Q38317578 | ||
| CpG methylation within the 5' regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site | Q38338770 | ||
| Inhibition of gene expression with ribozymes. | Q40451946 | ||
| A role for Id-1 in the aggressive phenotype and steroid hormone response of human breast cancer cells. | Q40892143 | ||
| Transcription of BRCA1 is dependent on the formation of a specific protein-DNA complex on the minimal BRCA1 Bi-directional promoter | Q40921685 | ||
| Genetic modification of human B-cell development: B-cell development is inhibited by the dominant negative helix loop helix factor Id3. | Q40924102 | ||
| Inherited breast and ovarian cancer. | Q40934988 | ||
| Reduction of BRCA1 protein expression in Japanese sporadic breast carcinomas and its frequent loss in BRCA1-associated cases. | Q40944869 | ||
| Positive regulation of the BRCA1 promoter | Q40966164 | ||
| Antisense RNA to the putative tumor suppressor gene BRCA1 transforms mouse fibroblasts. | Q41233661 | ||
| Complex regulation of the BRCA1 gene. | Q42662013 | ||
| Simple RNA enzymes with new and highly specific endoribonuclease activities | Q43501578 | ||
| Intracellular application of hairpin ribozyme genes against hepatitis B virus | Q45760765 | ||
| Id helix-loop-helix proteins in cell growth and differentiation | Q47721621 | ||
| Structure, chromosomal localisation and expression of the murine dominant negative helix-loop-helix Id4 gene | Q48004248 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | ribozyme | Q205858 |
| negative regulation of transcription, DNA-templated | Q14633919 | ||
| Inhibitor of DNA binding 4, HLH protein | Q21114678 | ||
| genomics | Q222046 | ||
| P1104 | number of pages | 6 | |
| P304 | page(s) | 130-135 | |
| P577 | publication date | 2001-01-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach | |
| P478 | volume | 98 |
| Q33184078 | A functional gene discovery in the Fas-mediated pathway to apoptosis by analysis of transiently expressed randomized hybrid-ribozyme libraries |
| Q40288973 | A novel RNAi library based on partially randomized consensus sequences of nuclear receptors: identifying the receptors involved in amyloid beta degradation |
| Q35941616 | A role for Id proteins in mammary gland physiology and tumorigenesis |
| Q33308295 | A structural analysis of in vitro catalytic activities of hammerhead ribozymes |
| Q53357936 | Aberrant hypermethylation of ID4 gene promoter region increases risk of lymph node metastasis in T1 breast cancer. |
| Q33822636 | Analysis of gene expression in PTHrP-/- mammary buds supports a role for BMP signaling and MMP2 in the initiation of ductal morphogenesis |
| Q42502209 | BRCA1 dysfunction in sporadic basal-like breast cancer |
| Q35546588 | BRCA1 in hormone-responsive cancers |
| Q34064538 | BRCA1 transcriptionally regulates genes involved in breast tumorigenesis |
| Q37809456 | Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists |
| Q36602561 | Basal-like breast cancer and the BRCA1 phenotype |
| Q39230650 | C-SPACE (cleavage-specific amplification of cDNA ends): a novel method of ribozyme-mediated gene identification |
| Q31129755 | Cell migration and metastasis as targets of small RNA-based molecular genetic analyses. |
| Q34479003 | Characteristics of triple-negative breast cancer |
| Q42517538 | Checkpoint Kinase 1 Expression Predicts Poor Prognosis in Nigerian Breast Cancer Patients |
| Q37602286 | Clinical relevance of the triple-negative breast cancer concept: genetic basis and clinical utility of the concept |
| Q48551091 | Combined drug therapeutic strategies for the effective treatment of Triple Negative Breast Cancer |
| Q34112750 | Control genes and variability: absence of ubiquitous reference transcripts in diverse mammalian expression studies |
| Q38759920 | Developmental therapeutics for patients with breast cancer and central nervous system metastasis: current landscape and future perspectives. |
| Q34176503 | Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. |
| Q34268571 | Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma. |
| Q33523638 | Elevated endogenous expression of the dominant negative basic helix-loop-helix protein ID1 correlates with significant centrosome abnormalities in human tumor cells |
| Q52023842 | Emerging high-throughput drug target validation technologies. |
| Q31014975 | Enrichment during transdominant genetic experiments using a flow sorter |
| Q34559594 | Epigenetic inactivation of inhibitor of differentiation 4 (Id4) correlates with prostate cancer |
| Q58713511 | Epigenetic regulation of ID4 in breast cancer: tumor suppressor or oncogene? |
| Q38938253 | Epigenetic regulation of ID4 in the determination of the BRCAness phenotype in breast cancer. |
| Q89907583 | Expression and Prognostic Value of Id-4 in Patients with Esophageal Squamous Cell Carcinoma |
| Q55300491 | Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages. |
| Q73695289 | Fanconi anemia and breast cancer: what's the connection? |
| Q33217148 | Gene discovery by ribozyme and siRNA libraries |
| Q33201149 | Generation of an shRNAi expression library against the whole human transcripts |
| Q74455209 | Genetic selection and the lure of SIN |
| Q30908456 | Genetic selection for modulators of a retinoic-acid-responsive reporter in human cells |
| Q33223083 | Genome-wide application of RNAi to the discovery of potential drug targets |
| Q27006938 | Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers |
| Q34396332 | Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia |
| Q33815755 | HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. |
| Q35592119 | Helix-loop-helix proteins in mammary gland development and breast cancer |
| Q35618867 | ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities |
| Q26740452 | ID4 controls luminal lineage commitment in normal mammary epithelium and inhibits BRCA1 function in basal-like breast cancer |
| Q35534628 | ID4 regulates mammary gland development by suppressing p38MAPK activity |
| Q40580196 | ID4: a new player in the cancer arena |
| Q28262992 | Id family of helix-loop-helix proteins in cancer |
| Q28200732 | Id proteins at the cross-road of development and cancer |
| Q53347842 | Id proteins expression in prostate cancer: high-level expression of Id-4 in primary prostate cancer is associated with development of metastases. |
| Q46083464 | Id4 expression and its relationship to other Id genes during avian embryonic development |
| Q37618601 | Id4 promotes cell proliferation in hepatocellular carcinoma |
| Q54514641 | Id4 protein is highly expressed in triple-negative breast carcinomas: possible implications for BRCA1 downregulation. |
| Q24672401 | Id4 regulates mammary epithelial cell growth and differentiation and is overexpressed in rat mammary gland carcinomas |
| Q35989438 | Identification of BRCA1 Deficiency Using Multi-Analyte Estimation of BRCA1 and Its Repressors in FFPE Tumor Samples from Patients with Triple Negative Breast Cancer |
| Q31127273 | Identification of cellular cofactors for human immunodeficiency virus replication via a ribozyme-based genomics approach |
| Q30833048 | Identification of genes by hybrid ribozymes that couple cleavage activity with the unwinding activity of an endogenous RNA helicase |
| Q30921342 | Identification of genes involved in cell invasion by using a library of randomized hybrid ribozymes |
| Q56765488 | Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries |
| Q31091619 | Identification of metastasis-related genes in a mouse model using a library of randomized ribozymes |
| Q34606618 | Identification of the genes chemosensitizing hepatocellular carcinoma cells to interferon-α/5-fluorouracil and their clinical significance |
| Q34489002 | Increased ID4 expression, accompanied by mutant p53 accumulation and loss of BRCA1/2 proteins in triple-negative breast cancer, adversely affects survival |
| Q33205727 | Induction and characterization of taxol-resistance phenotypes with a transiently expressed artificial transcriptional activator library |
| Q42110876 | Induction of Lumen Formation in a Three-dimensional Model of Mammary Morphogenesis by Transcriptional Regulator ID4: ROLE OF CaMK2D IN THE EPIGENETIC REGULATION OF ID4 GENE EXPRESSION. |
| Q50494235 | Inhibition of HIV-1 Integrase gene expression by 10-23 DNAzyme. |
| Q48206468 | Inhibitor of DNA binding-4 promotes angiogenesis and growth of glioblastoma multiforme by elevating matrix GLA levels |
| Q38289940 | Inhibitor of differentiation 4 (ID4): From development to cancer |
| Q33462003 | Inhibitor of differentiation 4 (Id4) is a potential tumor suppressor in prostate cancer |
| Q37439940 | Inhibitor of differentiation proteins do not influence prognosis of biliary tract cancer |
| Q31134096 | Inverse Genomics as a powerful tool to identify novel targets for the treatment of neurodegenerative diseases |
| Q39718983 | Involvement of MyoD and c-myb in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene. |
| Q24514478 | Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation |
| Q31155669 | Isolation of a peptide inhibitor of human rhinovirus |
| Q64060114 | LncRNA SNHG7 promotes pancreatic cancer proliferation through ID4 by sponging miR-342-3p |
| Q39535231 | MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development |
| Q34562257 | Minireview: Basal-like breast cancer: from molecular profiles to targeted therapies |
| Q40052411 | Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer. |
| Q34038170 | Molecular features of the basal-like breast cancer subtype based on BRCA1 mutation status |
| Q53374678 | New tools for functional mammalian cancer genetics |
| Q39204033 | Nrf2 is associated with the regulation of basal transcription activity of the BRCA1 gene. |
| Q44846367 | Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study |
| Q99569164 | Ovarian Cancer Risk Variants Are Enriched in Histotype-Specific Enhancers and Disrupt Transcription Factor Binding Sites |
| Q37947887 | PARP inhibitors--current status and the walk towards early breast cancer |
| Q37852615 | Phenotype-genotype correlation in familial breast cancer |
| Q37271818 | Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycle |
| Q35919277 | Polymorphisms in poly (ADP-ribose) polymerase-1 (PARP1) promoter and 3' untranslated region and their association with PARP1 expression in breast cancer patients |
| Q55120303 | Practical consensus recommendations on management of triple-negative metastatic breast cancer. |
| Q33748161 | Prevalence and predictors of loss of wild type BRCA1 in estrogen receptor positive and negative BRCA1-associated breast cancers |
| Q37388751 | Prognostic role of BRCA1 mutation in patients with triple-negative breast cancer |
| Q43566926 | Promoter methylation of ID4. A marker for recurrence-free survival in human breast cancer |
| Q24652213 | Promoter methylation-associated loss of ID4 expression is a marker of tumour recurrence in human breast cancer |
| Q24795166 | Regulation of BRCA1 expression and its relationship to sporadic breast cancer |
| Q35002431 | Regulation of BRCA1 transcription by specific single-stranded DNA binding factors |
| Q36680080 | Ribozyme technology for cancer gene target identification and validation |
| Q35107854 | Ribozymes: recent advances in the development of RNA tools |
| Q34557974 | Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL |
| Q33510463 | Survival Online: a web-based service for the analysis of correlations between gene expression and clinical and follow-up data |
| Q26850892 | Targeting triple-negative breast cancer: optimising therapeutic outcomes |
| Q28306121 | The ID proteins: master regulators of cancer stem cells and tumour aggressiveness |
| Q35868802 | The biology of progesterone receptor in the normal mammary gland and in breast cancer |
| Q38095764 | The complex genetic landscape of familial breast cancer |
| Q37767615 | The contribution of breast cancer pathology to statistical models to predict mutation risk in BRCA carriers |
| Q35218534 | The effect of the histone deacetylase inhibitor M344 on BRCA1 expression in breast and ovarian cancer cells |
| Q39794563 | The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis. |
| Q24791520 | The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer |
| Q30699664 | The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics |
| Q37931893 | Therapeutic potential of PARP inhibitors for metastatic breast cancer |
| Q35614098 | Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized |
| Q35745136 | Transcriptional control of the cell cycle in mammary gland development and tumorigenesis |
| Q37034915 | Transcriptional response of the murine mammary gland to acute progesterone exposure |
| Q35630269 | Triple negative breast cancer: unmet medical needs |
| Q57140329 | Triple-negative breast cancer |
| Q33326968 | Use of a U16 snoRNA-containing ribozyme library to identify ribozyme targets in HIV-1 |
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| Q35828457 | c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression |
| Q37521015 | miR-342 regulates BRCA1 expression through modulation of ID4 in breast cancer |
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