Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function

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Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.200109046
P932PMC publication ID2173479
P698PubMed publication ID11889140
P5875ResearchGate publication ID11474431

P2093author name stringDenis L Dujardin
Richard B Vallee
Chin-Yin Tai
Nicole E Faulkner
P2860cites workA role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein functionQ24290458
LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosomeQ24290783
Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transportQ24291366
Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150GluedQ24310526
Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosisQ24315967
Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2Q24319816
ZW10 helps recruit dynactin and dynein to the kinetochoreQ24322833
Reduction of microtubule catastrophe events by LIS1, platelet-activating factor acetylhydrolase subunit.Q24532866
Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochoresQ24555706
Regulation of cytoplasmic dynein function in vivo by the Drosophila Glued complexQ24651482
Evidence for a role of CLIP-170 in the establishment of metaphase chromosome alignmentQ24683148
The LIS1-related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO11 proteinQ24685903
Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDEQ26690426
The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2Q27732195
Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathwaysQ27931564
AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexesQ28131706
Lissencephaly associated mutations suggest a requirement for the PAFAH1B heterotrimeric complex in brain developmentQ28139341
The location and type of mutation predict malformation severity in isolated lissencephaly caused by abnormalities within the LIS1 geneQ28140296
Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrinQ28140669
Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeletonQ28140958
Dynactin increases the processivity of the cytoplasmic dynein motorQ28141898
A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous systemQ28143518
NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dyneinQ28143527
Overexpression of normal and mutant Arp1alpha (centractin) differentially affects microtubule organization during mitosis and interphaseQ28145296
Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actinQ28260376
Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeatsQ28261729
The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudCQ28271880
Structure of Tctex-1 and its interaction with cytoplasmic dynein intermediate chainQ28506995
Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1Q28565028
Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distributionQ29620185
Modulation of cytoplasmic dynein ATPase activity by the accessory subunitsQ31736972
The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membraneQ33793405
Cytoplasmic dynein is involved in nuclear migration in Aspergillus nidulansQ35092918
Dynein is a transient kinetochore component whose binding is regulated by microtubule attachment, not tensionQ36316545
In vitro motility from recombinant dynein heavy chainQ37529839
Dynamic association of cytoplasmic dynein heavy chain 1a with the Golgi apparatus and intermediate compartment.Q40915546
Cytoplasmic dynein intermediate chain phosphorylation regulates binding to dynactinQ43599362
Skeletal muscle myosin light chains are essential for physiological speeds of shortening.Q54650986
The LIS1-related protein NUDF of Aspergillus nidulans and its interaction partner NUDE bind directly to specific subunits of dynein and dynactin and to alpha- and gamma-tubulinQ56765523
An extended microtubule-binding structure within the dynein motor domainQ59096941
Nudf, a fungal homolog of the human LIS1 protein, functions as a dimer in vivoQ62660860
Vanadate-sensitized cleavage of dynein heavy chains by 365-nm irradiation of demembranated sperm flagella and its effect on the flagellar motilityQ70032356
Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complexQ71585895
Purification and characterization of bovine brain platelet-activating factor acetylhydrolaseQ72900252
Distinct but overlapping sites within the cytoplasmic dynein heavy chain for dimerization and for intermediate chain and light intermediate chain bindingQ73992927
Interaction mapping of a dynein heavy chain. Identification of dimerization and intermediate-chain binding domainsQ77772212
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
Platelet activating factor acetylhydrolase 1b regulatory subunit 1Q1982330
kinetochoreQ908912
dynein complex bindingQ21119987
P304page(s)959-68
P577publication date2002-03-18
P1433published inJournal of Cell BiologyQ1524550
P1476titleRole of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function
P478volume156

Reverse relations

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