MRGX Is a Novel Transcriptional Regulator That Exhibits Activation or Repression of the B-myb Promoter in a Cell Type-dependent Manner

scientific article published on September 23, 2003

MRGX Is a Novel Transcriptional Regulator That Exhibits Activation or Repression of the B-myb Promoter in a Cell Type-dependent Manner is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M309192200
P953full work available at URLhttp://www.jbc.org/content/278/49/49618.full.pdf
https://api.elsevier.com/content/article/PII:S002192582075742X?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S002192582075742X?httpAccept=text/xml
https://syndication.highwire.org/content/doi/10.1074/jbc.M309192200
P698PubMed publication ID14506250
P5875ResearchGate publication ID5907514

P2093author name stringKaoru Tominaga
James R. Smith
Paul Rookard
Johanna Echigo
James K. Leung
Olivia M. Pereira-Smith
P2860cites workInvolvement of the TIP60 histone acetylase complex in DNA repair and apoptosisQ24290159
RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrestQ24291072
MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14Q24291553
Characterization of the CHD family of proteinsQ24317090
Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genesQ24530628
A sequence motif found in aDrosophilaheterochromatin protein is conserved in animals and plantsQ24633125
E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complexQ24685706
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteinsQ27860456
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domainQ27860477
The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcription regulationQ27935520
Mammalian chromodomain proteins: their role in genome organisation and expressionQ28143752
MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activationQ28210381
Retinoblastoma protein recruits histone deacetylase to repress transcriptionQ28262144
Rb interacts with histone deacetylase to repress transcriptionQ28263985
The chromo superfamily: new members, duplication of the chromo domain and possible role in delivering transcription regulators to chromatinQ28285261
Conservation of the MORF4 related gene family: identification of a new chromo domain subfamily and novel protein motifQ28586948
A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOFQ28609758
Genetic analysis of indefinite division in human cells: identification of four complementation groupsQ33640611
Histone deacetylases, transcriptional control, and cancerQ33926323
ATP-dependent chromatin remodeling factors: nucleosome shufflers with many missionsQ34290276
Interaction of histone acetylases and deacetylases in vivoQ34463350
Genetics of cellular senescenceQ34667137
The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of DrosophilaQ37364351
Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4.Q37540466
Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and functionQ40547910
Replicative senescence: implications for in vivo aging and tumor suppressionQ41003046
Chromo-domain proteins: linking chromatin structure to epigenetic regulationQ47926670
The genomic organization, promoter position and expression profile of the mouse MRG15 geneQ48282840
Phenotype of low proliferative potential is dominant in hybrids of normal human fibroblastsQ70572057
Evidence for the recessive nature of cellular immortalityQ71810575
P433issue49
P407language of work or nameEnglishQ1860
P921main subjectbiochemistryQ7094
cell biologyQ7141
promoterQ224093
cell cycle proteinsQ76598519
P304page(s)49618-24
P577publication date2003-09-23
2003-12-05
P1433published inJournal of Biological ChemistryQ867727
P1476titleMRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner
MRGX Is a Novel Transcriptional Regulator That Exhibits Activation or Repression of the B-myb Promoter in a Cell Type-dependent Manner
P478volume278

Reverse relations

cites work (P2860)
Q24534923A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16
Q34754722Alternative splicing of the chromodomain protein Morf4l1 pre-mRNA has implications on cell differentiation in the developing chicken retina
Q33221067Early-senescing human skin fibroblasts do not demonstrate accelerated telomere shortening
Q37764053Emerging role of the MORF/MRG gene family in various biological processes, including aging
Q43153204Interaction of Pax6 with SPARC and p53 in brain of mice indicates Smad3 dependent auto-regulation
Q42788633Loss of the chromatin regulator MRG15 limits neural stem/progenitor cell proliferation via increased expression of the p21 Cdk inhibitor
Q41811712MRG15 activates the cdc2 promoter via histone acetylation in human cells
Q33836841MrgX is not essential for cell growth and development in the mouse
Q24561782PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice
Q64933175Proteasome regulation of the chromodomain protein MRG-1 controls the balance between proliferative fate and differentiation in the C. elegans germ line.
Q34638245RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.
Q41840928The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway.
Q34566036The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes
Q33318134Up regulation in gene expression of chromatin remodelling factors in cervical intraepithelial neoplasia

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