CD72 negatively regulates KIT-mediated responses in human mast cells

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CD72 negatively regulates KIT-mediated responses in human mast cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.0902450
P932PMC publication ID2824776
P698PubMed publication ID20100931
P5875ResearchGate publication ID41139245

P50authorDean D. MetcalfeQ90856971
Alasdair M GilfillanQ98184237
Geethani BandaraQ114441405
P2093author name stringAtsushi Kumanogoh
Tatsuki R Kataoka
P2860cites workLyn is required for normal stem cell factor-induced proliferation and chemotaxis of primary hematopoietic cellsQ24291395
SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domainQ24533530
Development, migration, and survival of mast cellsQ24549674
Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signalingQ28140151
Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responsesQ28189775
Identification of CD72 as a Lymphocyte Receptor for the Class IV Semaphorin CD100Q29036802
Suppression of normal and malignant kit signaling by a bispecific antibody linking kit with CD300aQ33329484
Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorderQ33784323
The CD200 receptor is a novel and potent regulator of murine and human mast cell functionQ34386529
The CD100-CD72 interaction: a novel mechanism of immune regulationQ34460685
Mast cell and immune inhibitory receptorsQ36315238
Integrated signalling pathways for mast-cell activationQ36392833
Src family kinases and lipid mediators in control of allergic inflammationQ36819933
Mast cells and mastocytosisQ36835143
Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disordersQ36842503
Nerve-mast cell and smooth muscle-mast cell interaction mediated by cell adhesion molecule-1, CADM1.Q37190821
Activation and function of the mTORC1 pathway in mast cellsQ37233311
Amplification mechanisms for the enhancement of antigen-mediated mast cell activationQ37259631
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit productQ38315689
Enhancement by monoclonal anti-Lyb-2 antibody of antigen-specific B lymphocyte expansion stimulated by TNP-Ficoll and T lymphocyte-derived factors.Q39104749
CD72 down-modulates BCR-induced signal transduction and diminishes survival in primary mature B lymphocytesQ39133323
B-cell co-receptor CD72 is expressed on NK cells and inhibits IFN-gamma production but not cytotoxicityQ39886814
Molecular mechanisms for the release of chemokines from human leukemic mast cell line (HMC)-1 cells activated by SCF and TNF-alpha: roles of ERK, p38 MAPK, and NF-kappaB.Q40325238
Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI.Q40640528
Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogeneQ40678754
Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis: contribution of src family kinase and PI3-kinase on calcium mobilization and cell migrationQ40736974
Positive regulation of c-Jun N-terminal kinase and TNF-alpha production but not histamine release by SHP-1 in RBL-2H3 mast cellsQ40905034
The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1.Q41008340
The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation.Q41042524
The c-kit ligand stem cell factor and anti-IgE promote expression of monocyte chemoattractant protein-1 in human lung mast cells.Q41075325
Establishment of an immature mast cell line from a patient with mast cell leukemiaQ41296878
Stem cell factor is a chemotactic factor for human mast cellsQ41435701
Inhibitory receptors, ITIM sequences and phosphatasesQ41514609
CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activationQ41700467
Activation of B lymphocytes by monovalent anti-Lyb-2 antibodiesQ42273163
The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligationQ42528491
Induction of B lymphocyte proliferation by monoclonal anti-Lyb 2 antibody.Q42823424
Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexesQ44902253
CD72, a coreceptor with both positive and negative effects on B lymphocyte development and functionQ46208076
Dual regulation of BCR-mediated growth inhibition signaling by CD72.Q46426359
The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient miceQ49157483
Stat4 suppresses the proliferation of connective tissue-type mast cells.Q53473580
Positive signaling through CD72 induces mitogen-activated protein kinase activation and synergizes with B cell receptor signals to induce X-linked immunodeficiency B cell proliferation.Q54001263
Positive Effects of SH2 Domain-containing Tyrosine Phosphatase SHP-1 on Epidermal Growth Factor- and Interferon-γ-stimulated Activation of STAT Transcription Factors in HeLa CellsQ56032134
Human Lyb-2 homolog CD72 is a marker for progenitor B-cell leukemiasQ67544291
Antigen receptor-mediated B cell death is blocked by signaling via CD72 or treatment with dextran sulfate and is defective in autoimmunity-prone miceQ71163123
Signalling by the W/Kit receptor tyrosine kinase is negatively regulated in vivo by the protein tyrosine phosphatase Shp1Q71167710
Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13)Q73023303
CD72 negatively regulates signaling through the antigen receptor of B cellsQ73368116
The duplicitous nature of the Lyn tyrosine kinase in growth factor signalingQ79791774
New developments in FcepsilonRI regulation, function and inhibitionQ80168002
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmast cellQ191989
KIT proto-oncogene, receptor tyrosine kinaseQ909409
mast cell degranulationQ14887719
P304page(s)2468-75
P577publication date2010-03-01
P1433published inJournal of ImmunologyQ3521441
P1476titleCD72 negatively regulates KIT-mediated responses in human mast cells
P478volume184

Reverse relations

cites work (P2860)
Q24612825Biology and function of neuroimmune semaphorins 4A and 4D
Q57490032CD100 Effects in Macrophages and Its Roles in Atherosclerosis
Q38954933CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcεRIα.
Q37693415CD72 regulates the growth of KIT-mutated leukemia cell line Kasumi-1.
Q42292311CEACAM1 long isoform has opposite effects on the growth of human mastocytosis and medullary thyroid carcinoma cells
Q52928859Effect of Sema4D on microglial function in middle cerebral artery occlusion mice.
Q35566591Glycogen synthase kinase-3β is a prosurvival signal for the maintenance of human mast cell homeostasis
Q89551468Killer Immunoglobulin-Like Receptor 2DL4 (CD158d) Regulates Human Mast Cells both Positively and Negatively: Possible Roles in Pregnancy and Cancer Metastasis
Q41043876Killer cell immunoglobulin-like receptor 2DL4 is expressed in and suppresses the cell growth of Langerhans cell histiocytosis
Q84742904Mast cells
Q38633155Mast cells in asthma--state of the art.
Q64259989Myo1f, an Unconventional Long-Tailed Myosin, Is a New Partner for the Adaptor 3BP2 Involved in Mast Cell Migration
Q38879174NKp46 regulates the production of serine proteases and IL-22 in human mast cells in urticaria pigmentosa
Q38033164Novel identified receptors on mast cells
Q36092456Regulation of mast cell responses in health and disease
Q47321853The role of semaphorins in immune responses and autoimmune rheumatic diseases

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