TNF-alpha, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages

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TNF-alpha, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages is …
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scholarly articleQ13442814

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P356DOI10.1189/JLB.0909610
P8608Fatcat IDrelease_7sgzm43ouvffnnhkde477uovc4
P3181OpenCitations bibliographic resource ID107765
P698PubMed publication ID20103767
P5875ResearchGate publication ID41148762

P50authorDaniele SolaQ37375736
Pier Paolo SainaghiQ37375756
P2093author name stringGian Carlo Avanzi
Federica Alciato
Luigi Castello
P2860cites workThe protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascadeQ24310383
Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responsesQ28236864
Genes specifically expressed at growth arrest of mammalian cellsQ28297811
Twist mediates suppression of inflammation by type I IFNs and AxlQ28509359
Gas6 inhibits apoptosis in vascular smooth muscle: role of Axl kinase and AktQ28570068
Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapyQ28584706
Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 familyQ28585446
Tyro-3 family receptors are essential regulators of mammalian spermatogenesisQ28585555
Establishment and characterization of a human histiocytic lymphoma cell line (U-937)Q29619570
Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.Q31929744
Identification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cellsQ33426080
Macrophage regulation by Tyro 3 family receptorsQ35031954
Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cellsQ35615917
Expression of receptor tyrosine kinase Axl and its ligand Gas6 in rheumatoid arthritis: evidence for a novel endothelial cell survival pathwayQ35786887
The scavenger receptor SR-A I/II (CD204) signals via the receptor tyrosine kinase Mertk during apoptotic cell uptake by murine macrophagesQ37283810
Requirement of phosphatidylinositol 3-kinase-dependent pathway and Src for Gas6-Axl mitogenic and survival activities in NIH 3T3 fibroblastsQ40022933
Mer receptor tyrosine kinase signaling: prevention of apoptosis and alteration of cytoskeletal architecture without stimulation or proliferationQ40740717
Gas6 anti-apoptotic signaling requires NF-kappa B activation.Q40796453
Sequence and functional relationships between androgen-binding protein/sex hormone-binding globulin and its homologs protein S, Gas6, laminin, and agrinQ41591437
Differentiation of the U-937 promonocytic cell line induced by phorbol myristate acetate or retinoic acid: effect of aurothiomalateQ41596395
Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.Q42431545
Inhibition of vascular endothelial growth factor receptor 2-mediated endothelial cell activation by Axl tyrosine kinase receptorQ45126742
Gas6, a ligand for the receptor protein-tyrosine kinase Tyro-3, is widely expressed in the central nervous systemQ48311967
Changes in the amount and distribution of prosomal subunits during the differentiation of U937 myeloid cells: high expression of p23KQ73228941
Increased expression of Axl tyrosine kinase after vascular injury and regulation by G protein-coupled receptor agonists in ratsQ77364249
Development and validation of an ELISA method for detection of growth arrest specific 6 (GAS6) protein in human plasmaQ80938118
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
negative regulation of interleukin-6 productionQ14864450
TNFQ18032037
Growth arrest specific 6Q21110911
P304page(s)869-75
P577publication date2010-05-01
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleTNF-alpha, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages
P478volume87

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cites work (P2860)
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