The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs

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The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1046414285
P356DOI10.1038/NATURE03362
P3181OpenCitations bibliographic resource ID947501
P698PubMed publication ID15759005
P5875ResearchGate publication ID7975404

P50authorNaokazu InoueQ73203723
Masahito IkawaQ37379856
Masaru OkabeQ37379874
P2093author name stringAyako Isotani
P2860cites workA novel chicken membrane-associated complement regulatory protein: molecular cloning and functional characterizationQ47806378
Behaviour of a sperm surface transmembrane glycoprotein basigin during epididymal maturation and its role in fertilization in miceQ48866890
Exposure of sperm head equatorin after acrosome reaction and its fate after fertilization in miceQ48875601
Requirement of CD9 on the egg plasma membrane for fertilizationQ48901381
Intracytoplasmic sperm injection in the mouseQ49058048
Mammalian sperm-egg fusion: the rat egg has complementary sites for a sperm protein that mediates gamete fusionQ50790440
Sperm from the Calmegin-Deficient Mouse Have Normal Abilities for Binding and Fusion to the Egg Plasma MembraneQ57174498
Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker proteinQ57174547
Capacitation-related changes in antigen distribution on mouse sperm heads and its relation to fertilization rate in vitroQ57174596
Penetration of human spermatozoa into the human zona pellucida and the zona-free hamster egg: a study of fertile donors and infertile patientsQ71183379
Severely reduced female fertility in CD9-deficient miceQ28142603
A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusionQ28291941
The gamete fusion process is defective in eggs of Cd9-deficient miceQ28505612
None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusionQ28510333
Tissue- and Species-Specific Expression of sp56, a Mouse Sperm Fertilization ProteinQ28513630
Calmegin is required for fertilin alpha/beta heterodimerization and sperm fertilityQ28589882
Possible function of the ADAM1a/ADAM2 Fertilin complex in the appearance of ADAM3 on the sperm surfaceQ28592718
SAMP32, a testis-specific, isoantigenic sperm acrosomal membrane-associated proteinQ30308811
Identification of the 48-kDa G11 protein from guinea pig testes as speradQ31117178
Direct Binding of the Ligand PSG17 to CD9 Requires a CD9 Site Essential for Sperm-Egg FusionQ33763806
Disruption of mouse CD46 causes an accelerated spontaneous acrosome reaction in spermQ34784569
Angiotensin-converting enzyme and male fertilityQ35927004
The role of complement component C3b and its receptors in sperm-oocyte interactionQ36630669
Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4.Q40981704
Fertilization defects in sperm from mice lacking fertilin beta.Q44471252
A human sperm antigen possibly involved in binding and/or fusion with zona-free hamster eggsQ44545391
The use of zona-free animal ova as a test-system for the assessment of the fertilizing capacity of human spermatozoaQ44780762
Sperm-egg fusion: events at the plasma membraneQ46105277
Analysis of loss of adhesive function in sperm lacking cyritestin or fertilin betaQ46230806
P433issue7030
P407language of work or nameEnglishQ1860
P921main subjectIzumo sperm-egg fusion 1Q21118496
Izumo sperm-egg fusion 1Q21497862
P304page(s)234-8
P577publication date2005-03-10
P1433published inNatureQ180445
P1476titleThe immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs
P478volume434

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Q37084769The mechanism of sperm–egg interaction and the involvement of IZUMO1 in fusion
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Q91785463The mouse curly whiskers (cw) mutations are recessive alleles of hephaestin-like 1 (Hephl1)
Q36742621The role of SPRASA in female fertility
Q33796306The roles of tetraspanins in HIV-1 replication
Q47069037The spe-42 gene is required for sperm-egg interactions during C. elegans fertilization and encodes a sperm-specific transmembrane protein
Q42399417The structure of sperm Izumo1 reveals unexpected similarities with Plasmodium invasion proteins
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Q26863278Transmembrane signal transduction in oocyte maturation and fertilization: focusing on Xenopus laevis as a model animal
Q34017272Tssk6 is required for Izumo relocalization and gamete fusion in the mouse
Q37013359Two HAP2-GCS1 homologs responsible for gamete interactions in the cellular slime mold with multiple mating types: Implication for common mechanisms of sexual reproduction shared by plants and protozoa and for male-female differentiation
Q36477094Ultrastructural dynamics of human reproduction, from ovulation to fertilization and early embryo development
Q34536805Unraveling the intricacies of mammalian fertilization
Q33826180Unresolved questions concerning mammalian sperm acrosomal exocytosis.
Q50940966Vaccination with an Epitope Peptide of IZUMO1 to Induce Contraception in Female Mice.
Q33870581Vaccine for human contraception targeting sperm Izumo protein and YLP12 dodecamer peptide
Q55038826Vaccines for immunological control of fertility.
Q38597724Vertebrate Reproduction
Q97438190Virus and eukaryote fusogen superfamilies
Q97870674Viruses in the reproductive tract: On their way to the germ line?
Q50214764Vwf K1362A resulted in failure of protein synthesis in mice
Q35551422β-catenin is a molecular switch that regulates transition of cell-cell adhesion to fusion

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