| scholarly article | Q13442814 |
| P2093 | author name string | R. Ivell | |
| C. Kirchhoff | |||
| I. Habben | |||
| N. Krull | |||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| WAP four-disulfide core domain 2 | Q21136674 | ||
| Epididymal Secretory Proteins | Q78240113 | ||
| spermatogenesis | Q36961 | ||
| P304 | page(s) | 350-7 | |
| P577 | publication date | 1991-08-01 | |
| P1433 | published in | Biology of Reproduction | Q4915061 |
| P1476 | title | A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors | |
| A Major Human Epididymis-Specific cDNA Encodes a Protein with Sequence Homology to Extracellular Proteinase Inhibitors1 | |||
| P478 | volume | 45 |
| Q24534896 | A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein |
| Q37108676 | A new marker for breast cancer diagnosis, human epididymis protein 4: A preliminary study. |
| Q50801132 | A predictive model combining human epididymal protein 4 and radiologic features for the diagnosis of ovarian cancer. |
| Q37657661 | Analysis of serum level of HE4 and CA125 considering selected risk factors among patients with endometrioid endometrial cancer |
| Q37107033 | Anti-HE4 antibodies in infertile women and women with ovarian cancer |
| Q34330422 | Antimicrobial activity of human EPPIN, an androgen-regulated, sperm-bound protein with a whey acidic protein motif |
| Q37473123 | Assessment of levels of the tumor markers HE4 and CA125 considering staging, grading and histological types of endometrial cancer |
| Q64113417 | Biomarkers and algorithms for diagnosis of ovarian cancer: CA125, HE4, RMI and ROMA, a review |
| Q47098698 | Can Replacing CA125 with HE4 in Risk of Malignancy Indices 1-4 Improve Diagnostic Performance in the Presurgical Assessment of Adnexal Tumors? |
| Q28506218 | Characterization of mouse Eppin and a gene cluster of similar protease inhibitors on mouse chromosome 2 |
| Q31117457 | Characterization of secretory proteins from cultured cauda epididymal cells that significantly sustain bovine sperm motility in vitro |
| Q33951141 | Cloning and sequencing of human Eppin: a novel family of protease inhibitors expressed in the epididymis and testis |
| Q36694400 | Cloning, characterization, and tissue distribution of porcine SPAI, a protein with a transglutaminase substrate domain and the WAP motif. |
| Q33881167 | Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas |
| Q47124965 | Comparison of the Serum Level of Cancer Antigen 125 and Human Epididymis Protein 4 in Ovarian Cancer Patients and Healthy Groups in Isfahan City |
| Q30440200 | Comprehensive analysis of HE4 expression in normal and malignant human tissues |
| Q37553857 | Correlation of serum HE4 with tumor size and myometrial invasion in endometrial cancer. |
| Q52627963 | Could HE4 level measurements during first-line chemotherapy predict response to treatment among ovarian cancer patients? |
| Q79171540 | DNA Microarray Analysis of Region-Specific Gene Expression in the Mouse Epididymis1 |
| Q35166076 | Detection of the HE4 protein in urine as a biomarker for ovarian neoplasms |
| Q35661217 | Detection of the HE4 protein in urine as a biomarker for ovarian neoplasms: Clinical correlates |
| Q37324626 | Development of a CA125-mesothelin cell adhesion assay as a screening tool for biologics discovery |
| Q37093435 | Diagnosis and preoperative predictive value of serum HE4 concentrations for optimal debulking in epithelial ovarian cancer |
| Q95728263 | Diagnostic Performance of Serum Human Epididymis Protein 4 (HE4) for Prediction of Malignancy in Ovarian Masses |
| Q51102188 | Diagnostic accuracy of serum HE4, CA125 and ROMA in patients with ovarian cancer: a meta-analysis. |
| Q35006871 | Diagnostic and prognostic impact of serum HE4 detection in endometrial carcinoma patients |
| Q51701060 | Diagnostic and prognostic value of serum human epididymis protein 4 in patients with primary fallopian tube carcinoma. |
| Q47956315 | Diagnostic and prognostic values of preoperative serum levels of YKL-40, HE-4 and DKK-3 in endometrial cancer |
| Q48325039 | Differential expression of the whey acidic protein gene during lactation in the brushtail possum (Trichosurus vulpecula). |
| Q86409672 | Differentiating stage 1 epithelial ovarian cancer from benign ovarian tumours using a combination of tumour markers HE4, CA125, and CEA and patient's age |
| Q51341963 | Discovery of biomarkers for endometrial cancer: current status and prospects. |
| Q34121607 | Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules |
| Q55280402 | Does the Risk of Ovarian Malignancy Algorithm Provide Better Diagnostic Performance Than HE4 and CA125 in the Presurgical Differentiation of Adnexal Tumors in Polish Women? |
| Q37708699 | Elevated serum concentrations of HE4 as a novel biomarker of disease severity and renal fibrosis in kidney disease |
| Q37201766 | Evaluation of HE4, CA-125, Risk of Ovarian Malignancy Algorithm (ROMA) and Risk of Malignancy Index (RMI) in the Preoperative Assessment of Patients with Adnexal Mass |
| Q84347023 | Evaluation of pleural fluid human epididymis 4 (HE4) as a marker of malignant pleural effusion |
| Q42596053 | Expression and characterization of an epididymis-specific gene |
| Q35017292 | Expression level of serum human epididymis 4 and its prognostic significance in human non-small cell lung cancer |
| Q53977487 | Expression of the BE-20 epididymal protein gene: in situ hybridization. |
| Q38052927 | From bench to bedside: discovery of ovarian cancer biomarkers using high-throughput technologies in the past decade |
| Q48077657 | Gene expression in the dog epididymis: a model for human epididymal function |
| Q33596721 | Gene expression in the epididymis. |
| Q26778227 | Glycosylation-Based Serum Biomarkers for Cancer Diagnostics and Prognostics |
| Q37434141 | HE4 (WFDC2) gene overexpression promotes ovarian tumor growth |
| Q43603831 | HE4 and CA125 levels in the preoperative assessment of endometrial cancer patients: a prospective multicenter study (ENDOMET). |
| Q34611530 | HE4 as a biomarker for ovarian and endometrial cancer management |
| Q55430421 | HE4 level in ascites may assess the ovarian cancer chemotherapeutic effect. |
| Q88624194 | HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells |
| Q37375504 | HE4 transcription- and splice variants-specific expression in endometrial cancer and correlation with patient survival. |
| Q41588744 | HE4, CA125, the Risk of Malignancy Algorithm and the Risk of Malignancy Index and complex pelvic masses - a prospective comparison in the pre-operative evaluation of pelvic masses in an Australian population |
| Q38766453 | HE4-test of urine and body fluids for diagnosis of gynecologic cancer |
| Q49199791 | Human Epididymis Protein 4 Promotes Events Associated with Metastatic Ovarian Cancer via Regulation of the Extracelluar Matrix |
| Q47632159 | Human Epididymis Protein 4 as a Potential Biomarker of Chronic Kidney Disease in Female Patients With Normal Ovarian Function |
| Q89178547 | Human Epididymis Protein 4: A Novel Biomarker for Lupus Nephritis and Chronic Kidney Disease in Systemic Lupus Erythematosus |
| Q34983422 | Human epididymis protein 4 and secretory leukocyte protease inhibitor in vaginal fluid: relation to vaginal components and bacterial composition |
| Q56836325 | Human epididymis protein 4 as a serum marker for diagnosis of endometrial carcinoma and prediction of clinical outcome |
| Q51137244 | Human epididymis protein 4 immunostaining of malignant ascites differentiates cancer of Müllerian origin from gastrointestinal cancer. |
| Q84934387 | Human epididymis protein 4 is a biomarker for transitional cell carcinoma in the urinary system |
| Q47120251 | Human epididymis protein 4 may not be a reliable screening biomarker for detecting lung carcinoma patients |
| Q24303274 | Human epididymis protein-4 (HE-4): a novel cross-class protease inhibitor |
| Q46217516 | Identification and characterization of Wfdc gene expression in the male reproductive tract of the rat. |
| Q27641731 | Identification of a novel family of proteins in snake venoms. Purification and structural characterization of nawaprin from Naja nigricollis snake venom |
| Q42642174 | Identification of a rabbit epididymal protein gene |
| Q35688448 | Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis |
| Q26825152 | In 2014, can we do better than CA125 in the early detection of ovarian cancer? |
| Q99609211 | Increased levels of HE4 (WFDC2) in systemic sclerosis: a novel biomarker reflecting interstitial lung disease severity? |
| Q64938958 | Interaction of HE4 and ANXA2 exists in various malignant cells-HE4-ANXA2-MMP2 protein complex promotes cell migration. |
| Q47970212 | Investigation of the expression and functional significance of the novel mouse sperm protein, a disintegrin and metalloprotease with thrombospondin type 1 motifs number 10 (ADAMTS10). |
| Q24305407 | Major human epididymis-specific gene product, HE3, is the first representative of a novel gene family |
| Q49163911 | MicroRNA-149 sensitizes colorectal cancer to radiotherapy by downregulating human epididymis protein 4. |
| Q35759059 | Molecular Markers of Tubulointerstitial Fibrosis and Tubular Cell Damage in Patients with Chronic Kidney Disease |
| Q77321388 | Molecular and functional characterization of a recombinant protein of Trichuris trichiura |
| Q28578517 | Molecular cloning and expression of ps20 growth inhibitor. A novel WAP-type "four-disulfide core" domain protein expressed in smooth muscle |
| Q74645588 | Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray |
| Q37090503 | New insights into epididymal biology and function |
| Q56899522 | New nucleotide sequence data on the EMBL File Server |
| Q33622587 | Overexpression of elafin in ovarian carcinoma is driven by genomic gains and activation of the nuclear factor kappaB pathway and is associated with poor overall survival |
| Q38991579 | Physiopathological factors affecting the diagnostic value of serum HE4-test for gynecologic malignancies |
| Q47835422 | Potential association between elevated serum human epididymis protein 4 and renal fibrosis: A systemic review and meta-analysis. |
| Q34960174 | Potential markers for detection and monitoring of ovarian cancer. |
| Q44049941 | Preoperative HE4 expression in plasma predicts surgical outcome in primary ovarian cancer patients: results from the OVCAD study |
| Q53402383 | Prognostic value of human epididymis protein 4 in endometrial cancer and its utility for surgical staging. |
| Q57816120 | Prognostic values of HE4 expression in patients with cancer: a meta-analysis |
| Q28295249 | Proteins with whey-acidic-protein motifs and cancer |
| Q41627901 | Recent advances in andrology research: physiopathology and clinical application to fertility and infertility |
| Q42825685 | Regulatory function of whey acidic protein in the proliferation of mouse mammary epithelial cells in vivo and in vitro |
| Q38730370 | Role of human epididymis protein 4 in chemoresistance and prognosis of epithelial ovarian cancer |
| Q94512049 | Role of trypsin and protease-activated receptor-2 in ovarian cancer |
| Q38202841 | Seminal plasma as a diagnostic fluid for male reproductive system disorders |
| Q39388741 | Serum HE4 as a diagnostic and prognostic marker for lung cancer |
| Q43744083 | Serum HE4 as a prognostic marker in endometrial cancer--a population based study |
| Q35207172 | Serum HE4 is more suitable as a biomarker than CA125 in Chinese women with benign gynecologic disorders |
| Q35648196 | Serum HE4: An Independent Prognostic Factor in Non-Small Cell Lung Cancer |
| Q104756935 | Serum Human Epididymal Protein 4 is Associated with Depressive Symptoms in Patients with Chronic Obstructive Pulmonary Disease |
| Q91793524 | Serum Human Epididymis Protein 4 is Associated with Renal Function and Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus |
| Q56945706 | Serum and bronchial aspiration fluid HE-4 levels in lung cancer |
| Q50698085 | Serum concentrations of HE4 change little during in vitro fertilization. |
| Q91966887 | Serum human epididymis protein 4 level as a predictor of clinical worsening in idiopathic pulmonary arterial hypertension: a pilot study |
| Q47109874 | Serum human epididymis protein 4 levels in colorectal cancer patients |
| Q34788262 | Sperm-associated antigen 11A is expressed exclusively in the principal cells of the mouse caput epididymis in an androgen-dependent manner. |
| Q92877025 | The Application Value of Serum HE4 in the Diagnosis of Lung Cancer |
| Q51435881 | The Establishment of an HE4-CLIA Method and the Combined Analysis of HE4 and CA125 in Ovarian Cancer. |
| Q57204281 | The Gene for a Novel Member of the Whey Acidic Protein Family Encodes Three Four-disulfide Core Domains and Is Asynchronously Expressed during Lactation |
| Q95660727 | The biomarker HE4 (WFDC2) promotes a pro-angiogenic and immunosuppressive tumor microenvironment via regulation of STAT3 target genes |
| Q35129350 | The comparative biology of whey proteins |
| Q51082273 | The diagnosis and pathological value of combined detection of HE4 and CA125 for patients with ovarian cancer. |
| Q26992102 | The emerging role of HE4 in the evaluation of epithelial ovarian and endometrial carcinomas |
| Q34124743 | The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms |
| Q39437253 | The role of HE4 in ovarian cancer: inhibiting tumour cell proliferation and metastasis |
| Q38388103 | The role of human epididymis protein 4 in the diagnosis of epithelial ovarian cancer |
| Q33508672 | The role of proteomics in the diagnosis and treatment of ovarian cancer |
| Q30470448 | The role of the epididymis in the protection of spermatozoa |
| Q48785451 | The toposome, essential for sea urchin cell adhesion and development, is a modified iron-less calcium-binding transferrin |
| Q28145061 | The whey acidic protein family: a new signature motif and three-dimensional structure by comparative modeling |
| Q31031977 | Three genes expressing Kunitz domains in the epididymis are related to genes of WFDC-type protease inhibitors and semen coagulum proteins in spite of lacking similarity between their protein products |
| Q30414041 | Towards an evidence-based approach for diagnosis and management of adnexal masses: findings of the International Ovarian Tumour Analysis (IOTA) studies |
| Q40585739 | Transcriptional targeting in ovarian cancer cells using the human epididymis protein 4 promoter |
| Q37789033 | Tumor markers for early detection of ovarian cancer |
| Q35679368 | Value of detection of serum human epididymis secretory protein 4 and carbohydrate antigen 125 in diagnosis of early endometrial cancer of different pathological subtypes |
| Q21284411 | WFDC2 (HE4): a potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lung |
| Q55456882 | [Advances of human epididymis protein 4 in lung cancer]. |
| Q35021181 | fTwo novel biomarkers, mesothelin and HE4, for diagnosis of ovarian carcinoma |
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