| scholarly article | Q13442814 |
| P50 | author | A. John Camm | Q110902795 |
| Elijah Behr | Q60991814 | ||
| Mette Nyegaard | Q41638418 | ||
| Mads T. Søndergaard | Q41700358 | ||
| Paula Louise Hedley | Q42173385 | ||
| Anders D. Børglum | Q46997890 | ||
| Michael Toft Overgaard | Q47805032 | ||
| P2093 | author name string | Michael Christiansen | |
| Lasse L Hildebrandt | |||
| Inger Fosdal | |||
| Jacob Lund | |||
| Göran Wettrell | |||
| Marta Vranas | |||
| P2860 | cites work | A cardiac arrhythmia syndrome caused by loss of ankyrin-B function | Q24295030 |
| Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction | Q24302344 | ||
| PLINK: a tool set for whole-genome association and population-based linkage analyses | Q24677407 | ||
| Calmodulin structure refined at 1.7 A resolution | Q27643035 | ||
| Calcium-induced conformational transition revealed by the solution structure of apo calmodulin | Q27729469 | ||
| Merlin--rapid analysis of dense genetic maps using sparse gene flow trees | Q27860829 | ||
| Primer3 on the WWW for general users and for biologist programmers | Q27861030 | ||
| Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein: expression in human reproductive and nonreproductive tissues | Q28144716 | ||
| HaploPainter: a tool for drawing pedigrees with complex haplotypes | Q80585999 | ||
| A novel early onset lethal form of catecholaminergic polymorphic ventricular tachycardia maps to chromosome 7p14-p22 | Q55843608 | ||
| Familial polymorphic ventricular arrhythmias: a quarter century of successful medical treatment based on serial exercise-pharmacologic testing | Q73250272 | ||
| Complex of calmodulin with a ryanodine receptor target reveals a novel, flexible binding mode | Q79207756 | ||
| Calcium binding to calmodulin mutants having domain-specific effects on the regulation of ion channels | Q79384862 | ||
| Some precautions in using chelators to buffer metals in biological solutions | Q79740748 | ||
| Genotypic heterogeneity and phenotypic mimicry among unrelated patients referred for catecholaminergic polymorphic ventricular tachycardia genetic testing | Q79833033 | ||
| Distinct U wave changes in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT) | Q79845488 | ||
| Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia | Q28201561 | ||
| A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel | Q28204838 | ||
| Catecholaminergic polymorphic ventricular tachycardia | Q28287523 | ||
| Diagnosis and treatment of catecholaminergic polymorphic ventricular tachycardia | Q28299768 | ||
| Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor. | Q30494293 | ||
| Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia. | Q33147854 | ||
| Targeted mutational analysis of the RyR2-encoded cardiac ryanodine receptor in sudden unexplained death: a molecular autopsy of 49 medical examiner/coroner's cases | Q33152066 | ||
| Sudden arrhythmic death syndrome: familial evaluation identifies inheritable heart disease in the majority of families. | Q33156318 | ||
| Dissociation of calmodulin from cardiac ryanodine receptor causes aberrant Ca(2+) release in heart failure. | Q34514645 | ||
| Catecholaminergic polymorphic ventricular tachycardia: recent mechanistic insights | Q34557909 | ||
| Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca²⁺release leading to catecholaminergic polymorphic ventricular tachycardia. | Q35156823 | ||
| Idiopathic ventricular tachycardia: Diagnosis and management | Q36696017 | ||
| Mechanisms of human arrhythmia syndromes: abnormal cardiac macromolecular interactions | Q36967654 | ||
| Catecholaminergic polymorphic ventricular tachycardia: A paradigm to understand mechanisms of arrhythmias associated to impaired Ca(2+) regulation | Q37625277 | ||
| Mechanism of local and global Ca2+ sensing by calmodulin in complex with a Ca2+ channel | Q39967546 | ||
| Intermolecular tuning of calmodulin by target peptides and proteins: differential effects on Ca2+ binding and implications for kinase activation | Q42847834 | ||
| Detecting polymorphisms and mutations in candidate genes | Q43208691 | ||
| Calcium binding to calmodulin leads to an N-terminal shift in its binding site on the ryanodine Receptor | Q43508383 | ||
| Molecular Basis of Calmodulin Binding to Cardiac Muscle Ca2+ Release Channel (Ryanodine Receptor) | Q44411401 | ||
| U-waves and T-wave peak to T-wave end intervals in patients with catecholaminergic polymorphic ventricular tachycardia, effects of beta-blockers | Q46311440 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | ventricular tachycardia | Q56002 |
| tachycardia | Q209583 | ||
| Ryanodine receptor 2 | Q3415811 | ||
| calmodulin binding | Q14819275 | ||
| Calmodulin-1 | Q22676983 | ||
| Calmodulin 1 | Q59706382 | ||
| P304 | page(s) | 703-712 | |
| P577 | publication date | 2012-10-01 | |
| P1433 | published in | American Journal of Human Genetics | Q4744249 |
| P1476 | title | Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death | |
| P478 | volume | 91 |
| Q47144880 | A Precision Medicine Approach to the Rescue of Function on Malignant Calmodulinopathic Long-QT Syndrome. |
| Q47139491 | A framework for exhaustively mapping functional missense variants. |
| Q33164590 | A novel cardiac ryanodine receptor gene (RyR2) mutation in an athlete with aborted sudden cardiac death: a case of adult-onset catecholaminergic polymorphic ventricular tachycardia |
| Q41885182 | A novel de novo calmodulin mutation in a 6-year-old boy who experienced an aborted cardiac arrest |
| Q38829197 | A novel heterozygous mutation in cardiac calsequestrin causes autosomal dominant catecholaminergic polymorphic ventricular tachycardia |
| Q38547497 | A rendezvous with the queen of ion channels: Three decades of ion channel research by David T Yue and his Calcium Signals Laboratory. |
| Q37592304 | A statistical framework to guide sequencing choices in pedigrees |
| Q39022381 | Advances in the diagnosis and treatment of catecholaminergic polymorphic ventricular tachycardia |
| Q47940875 | Allele-specific ablation rescues electrophysiological abnormalities in a human iPS cell model of long-QT syndrome with a CALM2 mutation |
| Q57805497 | Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel |
| Q41760210 | Arrhythmogenic Calmodulin Mutations Affect the Activation and Termination of Cardiac Ryanodine Receptor-mediated Ca2+ Release |
| Q42065538 | Arrhythmogenic calmodulin mutations disrupt intracellular cardiomyocyte Ca2+ regulation by distinct mechanisms |
| Q29147431 | Arrhythmogenic calmodulin mutations impede activation of small-conductance calcium-activated potassium current |
| Q38283933 | Arrhythmogenic mechanisms in ryanodine receptor channelopathies. |
| Q91702639 | Assessing predictions on fitness effects of missense variants in calmodulin |
| Q89856015 | Atropine-induced sinus tachycardia protects against exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia |
| Q91979959 | CAGI5: Objective performance assessments of predictions based on the Evolutionary Action equation |
| Q34451319 | CALM3 mutation associated with long QT syndrome |
| Q46118392 | CALMing Down Arrhythmogenic Calmodulinopathies via a Precision Medicine Approach |
| Q42367519 | CPVT-associated cardiac ryanodine receptor mutation G357S with reduced penetrance impairs Ca2+ release termination and diminishes protein expression |
| Q61446188 | Ca-dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains |
| Q41112224 | CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift |
| Q90248065 | Calcium Handling Defects and Cardiac Arrhythmia Syndromes |
| Q39360546 | Calcium Signaling and Cardiac Arrhythmias |
| Q92701787 | Calcium as a Key Player in Arrhythmogenic Cardiomyopathy: Adhesion Disorder or Intracellular Alteration? |
| Q46098683 | Calcium-Dependent Structural Dynamics of a Spin-Labeled RyR Peptide Bound to Calmodulin. |
| Q35995795 | Calmodulin 2 Mutation N98S Is Associated with Unexplained Cardiac Arrest in Infants Due to Low Clinical Penetrance Electrical Disorders |
| Q89861027 | Calmodulin Mutations Associated with Heart Arrhythmia: A Status Report |
| Q89698195 | Calmodulin and Calmodulin Binding Proteins in Dictyostelium: A Primer |
| Q38105647 | Calmodulin in a heartbeat |
| Q92717757 | Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814 |
| Q42551776 | Calmodulin mutations associated with long QT syndrome prevent inactivation of cardiac L-type Ca(2+) currents and promote proarrhythmic behavior in ventricular myocytes |
| Q37327429 | Calmodulin mutations associated with recurrent cardiac arrest in infants |
| Q33165145 | Calmodulin mutations causing catecholaminergic polymorphic ventricular tachycardia confer opposing functional and biophysical molecular changes |
| Q26827282 | Calmodulin regulation (calmodulation) of voltage-gated calcium channels |
| Q60046053 | Calmodulinopathy: A Novel, Life-Threatening Clinical Entity Affecting the Young |
| Q60959820 | Calmodulinopathy: Functional Effects of CALM Mutations and Their Relationship With Clinical Phenotypes |
| Q37728178 | Cardiac Channelopathies and Sudden Death: Recent Clinical and Genetic Advances |
| Q51751600 | Cardiac channelopathies associated with infantile fatal ventricular arrhythmias: from the cradle to the bench. |
| Q39057143 | Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure. |
| Q52333945 | Catecholaminergic Polymorphic Ventricular Tachycardia - Looking to the Future. |
| Q90447356 | Catecholaminergic polymorphic ventricular tachycardia due to de novo RyR2 mutation: recreational cycling as a trigger of lethal arrhythmias |
| Q58601770 | Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry |
| Q48161835 | Catecholaminergic polymorphic ventricular tachycardia, an update. |
| Q26747056 | Catecholaminergic polymorphic ventricular tachycardia: An exciting new era |
| Q27303698 | Channel Activity of Cardiac Ryanodine Receptors (RyR2) Determines Potency and Efficacy of Flecainide and R-Propafenone against Arrhythmogenic Calcium Waves in Ventricular Cardiomyocytes |
| Q90170780 | Classification and correlation of RYR2 missense variants in individuals with catecholaminergic polymorphic ventricular tachycardia reveals phenotypic relationships |
| Q35702068 | Common Variants in TRDN and CALM1 Are Associated with Risk of Sudden Cardiac Death in Chronic Heart Failure Patients in Chinese Han Population |
| Q99421604 | Complex Arrhythmia Syndrome in a Knock-In Mouse Model Carrier of the N98S Calm1 Mutation |
| Q36659085 | Conserved properties of individual Ca2+-binding sites in calmodulin |
| Q91897792 | Crystal structures of Ca2+-calmodulin bound to NaV C-terminal regions suggest role for EF-hand domain in binding and inactivation |
| Q38125941 | Current perspectives in genetic cardiovascular disorders: from basic to clinical aspects |
| Q28076784 | Current topics in catecholaminergic polymorphic ventricular tachycardia |
| Q37642018 | Divergent Soybean Calmodulins Respond Similarly to Calcium Transients: Insight into Differential Target Regulation |
| Q37708601 | Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants. |
| Q47297069 | EL20, A Potent Antiarrhythmic Compound, Selectively Inhibits Calmodulin Deficient Ryanodine Receptor Type 2. |
| Q90466645 | Effective cascade screening through identification of a mutation in RYR2 in a large family with a history of sudden death |
| Q92921030 | Efficacy of Flecainide in Catecholaminergic Polymorphic Ventricular Tachycardia Is Mutation-Independent but Reduced by Calcium Overload |
| Q47334714 | Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes. |
| Q37228910 | Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP |
| Q58010261 | Executive Summary: HRS/EHRA/APHRS Expert Consensus Statement on the Diagnosis and Management of Patients with Inherited Primary Arrhythmia Syndromes |
| Q45027885 | Executive summary: HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes |
| Q35037204 | Functional role of voltage gated Ca(2+) channels in heart automaticity. |
| Q35675536 | Gender Differences in the Inheritance Mode of RYR2 Mutations in Catecholaminergic Polymorphic Ventricular Tachycardia Patients |
| Q52714512 | Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin-Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia. |
| Q38125385 | Genetic testing for inherited cardiac disease |
| Q38203394 | Genetic testing in cardiovascular diseases |
| Q52866707 | Genetic variations involved in sudden cardiac death and their associations and interactions. |
| Q64101859 | Genetics and clinics: current applications, limitations, and future developments |
| Q26783570 | Genetics of inherited primary arrhythmia disorders |
| Q91719561 | Genome-wide association study identifies locus at chromosome 2q32.1 associated with syncope and collapse |
| Q46129436 | Genomic-based diagnosis of arrhythmia disease in a personalized medicine era. |
| Q58010282 | HRS/EHRA/APHRS Expert Consensus Statement on the Diagnosis and Management of Patients with Inherited Primary Arrhythmia Syndromes |
| Q59335621 | Human Calmodulin Mutations |
| Q90519863 | Impact of arrhythmogenic calmodulin variants on small conductance Ca2+ -activated K+ (SK3) channels |
| Q34036797 | Impact of genetics on the clinical management of channelopathies |
| Q35514666 | Impaired calcium-calmodulin-dependent inactivation of Cav1.2 contributes to loss of sarcoplasmic reticulum calcium release refractoriness in mice lacking calsequestrin 2. |
| Q28071914 | Inherited ion channel diseases: a brief review |
| Q89979979 | Integrin β1D Deficiency-Mediated RyR2 Dysfunction Contributes to Catecholamine-Sensitive Ventricular Tachycardia in ARVC |
| Q90678000 | Interplay between Triadin and Calsequestrin in the Pathogenesis of CPVT in the Mouse |
| Q51061793 | Interpreting Incidentally Identified Variants in Genes Associated With Catecholaminergic Polymorphic Ventricular Tachycardia in a Large Cohort of Clinical Whole-Exome Genetic Test Referrals. |
| Q87334959 | Ion Channel Diseases: an Update for 2016 |
| Q52679005 | Ion Channel Disorders and Sudden Cardiac Death. |
| Q26829681 | Ion Channels in the Heart |
| Q90693822 | Long-Term Follow-Up of Patients with Catecholaminergic Polymorphic Ventricular Arrhythmia |
| Q38887628 | Management of survivors of cardiac arrest - the importance of genetic investigation |
| Q55060450 | Modelling human calmodulinopathies with induced pluripotent stem cells: progress and challenges. |
| Q89961129 | Molecular and tissue mechanisms of catecholaminergic polymorphic ventricular tachycardia |
| Q34441392 | Multiple modes of ryanodine receptor 2 inhibition by flecainide. |
| Q38188482 | Negative autopsy and sudden cardiac death. |
| Q30982059 | New Family With Catecholaminergic Polymorphic Ventricular Tachycardia Linked to the Triadin Gene |
| Q38416344 | New approaches to establish genetic causality |
| Q38707932 | New challenges and promises in solid organ transplantation pharmacogenetics: the genetic variability of proteins involved in the pharmacodynamics of immunosuppressive drugs |
| Q33643625 | Novel CALM3 mutations in pediatric long QT syndrome patients support a CALM3-specific calmodulinopathy |
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| Q52687047 | Pathogenic mechanism of a catecholaminergic polymorphic ventricular tachycardia causing-mutation in cardiac calcium release channel RyR2. |
| Q28067569 | Patient Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Development and Screening In Catecholaminergic Polymorphic Ventricular Tachycardia |
| Q58693859 | Proarrhythmic Remodeling of Calcium Homeostasis in Cardiac Disease; Implications for Diabetes and Obesity |
| Q60951026 | Putative Loci Causing Early Embryonic Mortality in Duroc Swine |
| Q28074154 | Recent advances in genetic testing and counseling for inherited arrhythmias |
| Q37699206 | Recent genetic discoveries implicating ion channels in human cardiovascular diseases |
| Q38238961 | Sinus node dysfunction in catecholaminergic polymorphic ventricular tachycardia: risk factor and potential therapeutic target? |
| Q29147570 | Spectrum and Prevalence of CALM1-, CALM2-, and CALM3-Encoded Calmodulin Variants in Long QT Syndrome and Functional Characterization of a Novel Long QT Syndrome-Associated Calmodulin Missense Variant, E141G |
| Q57656681 | Structural Details of the Ryanodine Receptor Calcium Release Channel and Its Gating Mechanism |
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| Q26827729 | Sudden unexplained death in infants and children: the role of undiagnosed inherited cardiac conditions |
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