The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription

scientific article

The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.EMBOJ.7601306
P3181OpenCitations bibliographic resource ID2750072
P932PMC publication ID1570434
P698PubMed publication ID16957778
P5875ResearchGate publication ID6832052

P50authorJing LiangQ84841480
Yongfeng ShangQ84841596
P2093author name stringYan Wang
Ying Zhang
Hua Zhang
Xiaojing Sun
Luyang Sun
Ruifang Li
Wenhua Yu
Yupeng Chen
P2860cites workThe SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasomeQ24302180
The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptorsQ24304094
RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2Q24319818
TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1Q24321891
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300Q24324556
The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamilyQ24530578
GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptorsQ24600501
Ligand-induced estrogen receptor alpha degradation by the proteasome: new actors?Q25257822
Sequence and characterization of a coactivator for the steroid hormone receptor superfamilyQ27860465
Mechanisms underlying ubiquitinationQ27860656
The nuclear receptor superfamily: the second decadeQ27860725
The ubiquitin systemQ27860803
A system for stable expression of short interfering RNAs in mammalian cellsQ27860875
The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II.Q27939755
The coregulator exchange in transcriptional functions of nuclear receptorsQ28131759
Dimerization with retinoid X receptors and phosphorylation modulate the retinoic acid-induced degradation of retinoic acid receptors alpha and gamma through the ubiquitin-proteasome pathwayQ73929928
The human estrogen receptor-alpha is a ubiquitinated protein whose stability is affected differentially by agonists, antagonists, and selective estrogen receptor modulatorsQ74265958
An unexpected role for ubiquitylation of a transcriptional activatorQ81589258
The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processingQ81589292
Regulation of transcription by a protein methyltransferaseQ28138085
Functional interaction between the p160 coactivator proteins and the transcriptional enhancer factor family of transcription factorsQ28143075
Connections and regulation of the human estrogen receptorQ28201958
Combinatorial control of gene expression by nuclear receptors and coregulatorsQ28209095
Molecular determinants for the tissue specificity of SERMsQ28211516
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancerQ28245902
A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factorsQ28246411
CoCoA, a nuclear receptor coactivator which acts through an N-terminal activation domain of p160 coactivatorsQ28594257
Cofactor dynamics and sufficiency in estrogen receptor-regulated transcriptionQ29547846
Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoterQ29616537
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophyQ29619282
The proteasome: not just degrading anymoreQ30438604
Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteinsQ30450954
The ubiquitin-proteasome pathway and pathogenesis of human diseasesQ33540242
Nuclear receptor cofactors as chromatin remodelersQ33745092
CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor {alpha} by the proteasomeQ33837034
The SRC family of nuclear receptor coactivatorsQ33860695
The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivationQ33911291
The RNA polymerase II elongation complexQ34188475
Ubiquitin enters the new millenniumQ34388963
Human estrogen receptor-alpha: regulation by synthesis, modification and degradation.Q34712217
How the ubiquitin-proteasome system controls transcriptionQ35075758
Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription?Q35606829
Expanding functional diversity of the coactivatorsQ36064225
Rush hour at the promoter: how the ubiquitin-proteasome pathway polices the traffic flow of nuclear receptor-dependent transcriptionQ36110120
Differential gene regulation by the SRC family of coactivatorsQ36661242
Proteasome-dependent degradation of the human estrogen receptorQ37160826
Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signalingQ38356127
Ligand-independent and agonist-mediated degradation of estrogen receptor-alpha in breast carcinoma cells: evidence for distinct degradative pathwaysQ38490337
Influence of oestradiol and tamoxifen on oestrogen receptors-alpha and -beta protein degradation and non-genomic signalling pathways in uterine and breast carcinoma cellsQ40343980
Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminusQ40407591
Role of the proteasome in the regulation of estrogen receptor alpha turnover and function in MCF-7 breast carcinoma cells.Q40429902
Inhibition of the 26S proteasome blocks progesterone receptor-dependent transcription through failed recruitment of RNA polymerase II.Q40429907
Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptorQ40493369
cAMP-dependent protein kinase regulates ubiquitin-proteasome-mediated degradation and subcellular localization of the nuclear receptor coactivator GRIP1.Q40519257
Specific ubiquitin-conjugating enzymes promote degradation of specific nuclear receptor coactivatorsQ40660685
Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes.Q41070037
FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependentQ43516734
Diverse roles for ubiquitin-dependent proteolysis in transcriptional activationQ44605497
Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesisQ46851647
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectestrogenQ277954
P304page(s)4223-33
P577publication date2006-09-20
P1433published inThe EMBO JournalQ1278554
P1476titleThe catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription
P478volume25

Reverse relations

cites work (P2860)
Q35907414A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein
Q34236787ATBF1 inhibits estrogen receptor (ER) function by selectively competing with AIB1 for binding to the ER in ER-positive breast cancer cells
Q58790020BRMS1 coordinates with LSD1 and suppresses breast cancer cell metastasis
Q34121216CCCTC-binding factor acts upstream of FOXA1 and demarcates the genomic response to estrogen
Q55367849Checkpoint suppressor 1 suppresses transcriptional activity of ERα and breast cancer cell proliferation via deacetylase SIRT1.
Q37264100Cks1 enhances transcription efficiency at the GAL1 locus by linking the Paf1 complex to the 19S proteasome
Q39958759Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes.
Q40026501DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression
Q36210983ERα phosphorylation at Y537 by Src triggers E6-AP-ERα binding, ERα ubiquitylation, promoter occupancy, and target gene expression.
Q34520505Emerging roles of the 26S proteasome in nuclear hormone receptor-regulated transcription.
Q90736751Estrogen Receptors and Ubiquitin Proteasome System: Mutual Regulation
Q24318938GAS, a new glutamate-rich protein, interacts differentially with SRCs and is involved in oestrogen receptor function
Q33825397Genome wide transcriptional profiling in breast cancer cells reveals distinct changes in hormone receptor target genes and chromatin modifying enzymes after proteasome inhibition
Q24315496Identification of cytoplasmic proteins interacting with unliganded estrogen receptor α and β in human breast cancer cells
Q34628232Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells.
Q36788865Intersection of nuclear receptors and the proteasome on the epigenetic landscape
Q37039050Ischemic preconditioning-induced cardioprotection is lost in mice with immunoproteasome subunit low molecular mass polypeptide-2 deficiency
Q37238734JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation
Q35131133JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation
Q39973068Klotho is a target gene of PPAR-gamma.
Q40140606LMP2-specific inhibitors: chemical genetic tools for proteasome biology
Q24308737LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer
Q35874237Ligand-dependent degradation of SRC-1 is pivotal for progesterone receptor transcriptional activity
Q37397989MLL1 promotes cervical carcinoma cell tumorigenesis and metastasis through interaction with β-catenin
Q39406924MYC Modulation around the CDK2/p27/SKP2 Axis
Q37269111OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity
Q24309768Oestrogen causes ATBF1 protein degradation through the oestrogen-responsive E3 ubiquitin ligase EFP
Q35619604Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy.
Q40107103Potentiation of ICI182,780 (Fulvestrant)-induced estrogen receptor-alpha degradation by the estrogen receptor-related receptor-alpha inverse agonist XCT790.
Q64082521Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation
Q35948205Proteasome activity modulates chromatin modifications and RNA polymerase II phosphorylation to enhance glucocorticoid receptor-mediated transcription
Q33656037Reconciling the concurrent fast and slow cycling of proteins on gene promoters.
Q37188091Role of proteasomes in cellular regulation
Q24339520SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities
Q24304823SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm
Q41874295SUG-1 plays proteolytic and non-proteolytic roles in the control of retinoic acid target genes via its interaction with SRC-3.
Q36975173Serial ChIP as a tool to investigate the co-localization or exclusion of proteins on plant genes
Q24306404Steroid receptor coactivator-interacting protein (SIP) inhibits caspase-independent apoptosis by preventing apoptosis-inducing factor (AIF) from being released from mitochondria
Q34575899Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization
Q37295632Sumoylation of TCF21 downregulates the transcriptional activity of estrogen receptor-alpha
Q39282042Temporal profiling of lapatinib-suppressed phosphorylation signals in EGFR/HER2 pathways.
Q38248373The 26S proteasome and initiation of gene transcription
Q33384289The UPS: a promising target for breast cancer treatment.
Q34799913The histone modifications governing TFF1 transcription mediated by estrogen receptor
Q24309520The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer
Q50986605UTX promotes hormonally responsive breast carcinogenesis through feed-forward transcription regulation with estrogen receptor.
Q36799954Ubiquitin and proteasomes in transcription
Q35781803Ubiquitin-interaction motifs of RAP80 are critical in its regulation of estrogen receptor alpha.
Q35148080YSY01A, a Novel Proteasome Inhibitor, Induces Cell Cycle Arrest on G2 Phase in MCF-7 Cells via ERα and PI3K/Akt Pathways
Q24318720ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis
Q33825091sZIP, an alternative splice variant of ZIP, antagonizes transcription repression and growth inhibition by ZIP

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