Prohibitin, a protein downregulated by androgens, represses androgen receptor activity

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Prohibitin, a protein downregulated by androgens, represses androgen receptor activity is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1005493321
P356DOI10.1038/SJ.ONC.1209967
P3181OpenCitations bibliographic resource ID4736415
P698PubMed publication ID16964284
P5875ResearchGate publication ID6826915

P2093author name stringC L Bevan
Y Kawano
S M Powell
D Chotai
J Waxman
D A Dart
S C Gamble
V Reebye
A Varela-Carver
G N Brooke
M Odontiadis
P2860cites workAn estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogensQ22009952
Prohibitin Induces the Transcriptional Activity of p53 and Is Exported from the Nucleus upon Apoptotic SignalingQ24294918
Prohibitin co-localizes with Rb in the nucleus and recruits N-CoR and HDAC1 for transcriptional repressionQ24323389
Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptorQ24532913
Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cellsQ24607572
Recognition and accommodation at the androgen receptor coactivator binding interfaceQ24799399
High-efficiency transformation of mammalian cells by plasmid DNAQ27860469
Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins.Q27934000
Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondriaQ27934696
The prohibitin family of mitochondrial proteins regulate replicative lifespanQ27940160
Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F functionQ28137829
A putative coiled-coil domain of prohibitin is sufficient to repress E2F1-mediated transcription and induce apoptosisQ28187292
The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRTQ28239712
The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptorQ28263578
Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoterQ29616537
The role of coactivators in steroid hormone action.Q33786844
Transcriptional repression by nuclear hormone receptorsQ33826663
Distinct recognition modes of FXXLF and LXXLL motifs by the androgen receptorQ33978884
Retinoblastoma, a tumor suppressor, is a coactivator for the androgen receptor in human prostate cancer DU145 cells.Q34067036
Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptorQ34128784
BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonistsQ34348559
Nuclear receptors: a rendezvous for chromatin remodeling factorsQ35197820
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexesQ35974510
Isolation and characterization of complementary DNAs encoding human manganese-containing superoxide dismutaseQ36312887
Prohibitin, an evolutionarily conserved intracellular protein that blocks DNA synthesis in normal fibroblasts and HeLa cellsQ36958660
Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA.Q38308965
Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migrationQ40393756
Cyclin D1 binding to the androgen receptor (AR) NH2-terminal domain inhibits activation function 2 association and reveals dual roles for AR corepressionQ40493146
Androgen receptor is targeted to distinct subcellular compartments in response to different therapeutic antiandrogensQ40494172
Androgens target prohibitin to regulate proliferation of prostate cancer cells.Q40589151
Differential modulation of androgen receptor transcriptional activity by the nuclear receptor co-repressor (N-CoR).Q40595558
Differential regulation of Rb family proteins and prohibitin during camptothecin-induced apoptosisQ40722121
Formation of the androgen receptor transcription complexQ40740525
Characterization of prohibitin in a newly established rat ovarian granulosa cell lineQ40784641
A nuclear receptor corepressor modulates transcriptional activity of antagonist-occupied steroid hormone receptorQ41051243
Isolation of a cDNA that hybrid selects antiproliferative mRNA from rat liverQ44924689
A pp32-retinoblastoma protein complex modulates androgen receptor-mediated transcription and associates with components of the splicing machineryQ46594615
Synthetic progestins induce proliferation of breast tumor cell lines via the progesterone or estrogen receptor.Q52216577
Change of specificity mutations in androgen-selective enhancers. Evidence for a role of differential DNA binding by the androgen receptor.Q53993571
The human androgen receptor: domain structure, genomic organization and regulation of expression.Q54116950
Inhibition of the Dihydrotestosterone-Activated Androgen Receptor by Nuclear Receptor CorepressorQ55884170
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectProhibitinQ2112279
negative regulation of glucocorticoid receptor signaling pathwayQ21109584
P304page(s)1757-68
P577publication date2007-03-15
P1433published inOncogeneQ1568657
P1476titleProhibitin, a protein downregulated by androgens, represses androgen receptor activity
P478volume26

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cites work (P2860)
Q33557664A novel role for GSK3β as a modulator of Drosha microprocessor activity and MicroRNA biogenesis
Q36447412A repressive role for prohibitin in estrogen signaling.
Q33830761Aberrant expression of nuclear matrix proteins during HMBA-induced differentiation of gastric cancer cells
Q26740628Advances in genetics: widening our understanding of prostate cancer
Q34943321Androgen Receptor regulation of Vitamin D receptor in response of castration-resistant prostate cancer cells to 1α-Hydroxyvitamin D5 - a calcitriol analog
Q36734752Androgen receptor and prostate cancer
Q38314940Androgen receptor epigenetics.
Q36961208Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis
Q33922393Androgen receptor functions in prostate cancer development and progression
Q91676732Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer
Q38326097Androgen-regulated processing of the oncomir miR-27a, which targets Prohibitin in prostate cancer.
Q38908290Antiandrogens act as selective androgen receptor modulators at the proteome level in prostate cancer cells.
Q38866849Effect of estrogen on expression of prohibitin in white adipose tissue and liver of diet-induced obese rats
Q30428062Estrogen-regulated prohibitin is required for mouse uterine development and adult function.
Q58696754Gonadectomy in Mito-Ob mice revealed a sex-dimorphic relationship between prohibitin and sex steroids in adipose tissue biology and glucose homeostasis
Q28972422Manipulating prohibitin levels provides evidence for an in vivo role in androgen regulation of prostate tumours
Q46882539Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression.
Q37034181Nuclear receptor co-regulator Krüppel-like factor 9 and prohibitin 2 expression in estrogen-induced epithelial cell proliferation in the mouse uterus
Q34157750Preliminary quantitative profile of differential protein expression between rat L6 myoblasts and myotubes by stable isotope labeling with amino acids in cell culture
Q38288384Prohibitin - At the crossroads of obesity-linked diabetes and cancer.
Q24314424Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes
Q39657252Prohibitin is a cholesterol‐sensitive regulator of cell cycle transit
Q37728643Prohibitin is required for transcriptional repression by the WT1-BASP1 complex.
Q38092225Prohibitin ligands in cell death and survival: mode of action and therapeutic potential
Q35737753Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis
Q36829123Prohibitin( PHB) roles in granulosa cell physiology
Q64275992Prohibitin: a prime candidate for a pleiotropic effector that mediates sex differences in obesity, insulin resistance, and metabolic dysregulation
Q36187056Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens
Q24298419Repression of androgen receptor activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch effectors
Q34497715Roles of prohibitin in growth control and tumor suppression in human cancers
Q38074717Signaling pathways of prohibitin and its role in diseases
Q41893749Skp2 and Skp2B team up against Rb and p53.
Q33383797TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer.
Q64910810The novel long noncoding RNA LOC283070 is involved in the transition of LNCaP cells into androgen-independent cells via its interaction with PHB2.
Q42371544The prohibitin protein complex promotes mitochondrial stabilization and cell survival in hematologic malignancies
Q38433570The prohibitin-repressive interaction with E2F1 is rapidly inhibited by androgen signalling in prostate cancer cells

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