Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

scientific article

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1471-4159.2005.03181.X
P3181OpenCitations bibliographic resource ID868582
P698PubMed publication ID15953362
P5875ResearchGate publication ID7790121

P50authorThangiah GeethaQ37377702
P2093author name stringMarie W Wooten
Jeganathan Ramesh Babu
P2860cites workThe atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factorQ24290913
Structure and functional properties of the ubiquitin binding protein p62Q24292324
Structure of the ubiquitin-associated domain of p62 (SQSTM1) and implications for mutations that cause Paget's disease of boneQ24307892
p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteinsQ24311839
Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domainQ24316893
Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62.Q24523784
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A method to identify p62’s UBA domain interacting proteinsQ24801013
The PB1 domain and the PC motif-containing region are structurally similar protein binding modulesQ27642246
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Proteasome subunit Rpn1 binds ubiquitin-like protein domainsQ27930136
RING finger proteins: mediators of ubiquitin ligase activityQ28139717
Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds alpha-synuclein filamentsQ28141728
Identification of Src as a novel atypical protein kinase C-interacting proteinQ28145994
CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell SurvivalQ28183470
Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotectiveQ28185660
Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligaseQ28187365
Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathiesQ28205799
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregationQ28245143
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A proteomics approach to understanding protein ubiquitinationQ29547312
Impairment of the ubiquitin-proteasome system by protein aggregationQ29614556
Tau filament formation in transgenic mice expressing P301L tau.Q31442641
The p38 MAP kinase signaling pathway in Alzheimer's disease.Q35557306
The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.Q35558459
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Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's diseaseQ37681819
Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradationQ39961293
Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.Q40461698
NEDD8 protein is involved in ubiquitinated inclusion bodiesQ40676519
In vitro assembly and recognition of Lys-63 polyubiquitin chainsQ43615489
Characterization of cytoplasmic alpha-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cellsQ43758292
Proteasomal degradation of tau proteinQ44163168
Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasomeQ45007178
The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis.Q51040187
Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: possible role in tangle formation.Q53352974
Ubiquitin is conjugated with amino-terminally processed tau in paired helical filamentsQ70462570
Amyloid β-Protein Inhibits Ubiquitin-dependent Protein Degradation in VitroQ71996662
Impaired proteasome function in Alzheimer's diseaseQ73897101
P62 and the sequestosome, a novel mechanism for protein metabolismQ77735047
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)192-203
P577publication date2005-07-01
P1433published inJournal of NeurochemistryQ6295643
P1476titleSequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
P478volume94