Systematic analysis of human protein complexes identifies chromosome segregation proteins

scientific article

Systematic analysis of human protein complexes identifies chromosome segregation proteins is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2010Sci...328..593H
P356DOI10.1126/SCIENCE.1181348
P3181OpenCitations bibliographic resource ID1357589
P932PMC publication ID2989461
P698PubMed publication ID20360068
P5875ResearchGate publication ID42833298

P50authorAnthony A. HymanQ573389
Jan-Michael PetersQ1251783
Jan EllenbergQ1296661
Frank BuchholzQ1443007
Kim NasmythQ1741557
Richard M. DurbinQ4583003
Jean-Karim HérichéQ34388112
Björn HegemannQ41789405
Siegfried SchloissnigQ56337188
Ina PoserQ61093960
Jutta BulkescherQ70382868
Yusuke ToyodaQ89813047
Karl MechtlerQ28320558
Alexander SchleifferQ30350204
P2093author name stringHolger Stark
James R A Hutchins
Otto Hudecz
Mihail Sarov
Andrei Pozniakovsky
Christian Conrad
Laurence Pelletier
Steffen Lawo
Mikolaj Michal Slabicki
Bettina A Buschhorn
Martina M Sykora
Martina Augsburg
Marit Leuschner
Ines Steinmacher
Andrea Ssykor
David Comartin
P2860cites workBAC TransgeneOmics: a high-throughput method for exploration of protein function in mammalsQ33327076
Augmin: a protein complex required for centrosome-independent microtubule generation within the spindleQ36625777
The RecQ helicase-topoisomerase III-Rmi1 complex: a DNA structure-specific 'dissolvasome'?Q36991033
Systems biology of mammalian cell divisionQ37219439
A combined approach for the localization and tandem affinity purification of protein complexes from metazoans.Q50781176
gamma-TubulinQ74477001
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1Q79754843
Proteomic characterization of the human centrosome by protein correlation profilingQ24301045
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrityQ24308769
The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cellsQ24316058
Genes required for mitotic spindle assembly in Drosophila S2 cellsQ24629513
The Pfam protein families databaseQ24644670
Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegansQ24652264
Global analysis of protein localization in budding yeastQ27653962
Global analysis of protein expression in yeastQ27860658
The spindle-assembly checkpoint in space and timeQ27860766
Systematic functional analysis of the Caenorhabditis elegans genome using RNAiQ27860839
Proteome survey reveals modularity of the yeast cell machineryQ27929510
Global landscape of protein complexes in the yeast Saccharomyces cerevisiaeQ27938796
Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interferenceQ28473657
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genesQ29615188
A new logic for DNA engineering using recombination in Escherichia coliQ29615202
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegansQ29618013
The anaphase promoting complex/cyclosome: a machine designed to destroyQ29618398
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome IIIQ29618444
Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell divisionQ30487705
Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complexQ30497439
Genome-scale RNAi profiling of cell division in human tissue culture cellsQ30836392
RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cellsQ30856358
P433issue5978
P407language of work or nameEnglishQ1860
P921main subjectidentical protein bindingQ14762994
Platelet-activating factor acetylhydrolase, isoform 1b, subunit 1Q15319474
Cep170-like proteinQ21105091
NDC80 kinetochore complex componentQ21109472
Anaphase promoting complex subunit 16Q21111572
Mitotic spindle organizing protein 1Q21123007
Mitotic spindle organizing protein 2BQ21123014
NudE neurodevelopment protein 1Q21982880
Centrosomal protein 152Q21983022
Protein phosphatase 1, regulatory subunit 10Q21989931
P304page(s)593-9
P577publication date2010-04-30
P1433published inScienceQ192864
P1476titleSystematic analysis of human protein complexes identifies chromosome segregation proteins
P478volume328

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cites work (P2860)
Q37530511A DNA vaccine targeting p42.3 induces protective antitumor immunity via eliciting cytotoxic CD8+T lymphocytes in a murine melanoma model
Q36713868A Dynamical Framework for the All-or-None G1/S Transition.
Q38165926A Functional Proteomics Perspective of DBC1 as a Regulator of Transcription
Q47198684A High-Resolution Proteomic Landscaping of Primary Human Dental Stem Cells: Identification of SHED- and PDLSC-Specific Biomarkers.
Q50522003A Homozygous Nme7 Mutation Is Associated with Situs Inversus Totalis.
Q50911867A Splice Variant of Centrosomin Converts Mitochondria to Microtubule-Organizing Centers.
Q24297808A census of human soluble protein complexes
Q27320769A critical function of Mad2l2 in primordial germ cell development of mice
Q24338151A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia
Q38655263A genome-scale resource for in vivo tag-based protein function exploration in C. elegans
Q34589246A genomic toolkit to investigate kinesin and myosin motor function in cells
Q30500031A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue
Q27936244A human interactome in three quantitative dimensions organized by stoichiometries and abundances
Q34545779A kinetic model for RNA-interference of focal adhesions
Q90083281A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission
Q35822248A primary microcephaly protein complex forms a ring around parental centrioles.
Q44237490A protein phosphatase 2A complex spatially controls plant cell division
Q44086938A quantitative liposome microarray to systematically characterize protein-lipid interactions
Q21089894A rapid FACS-based strategy to isolate human gene knockin and knockout clones
Q39296177A shRNA functional screen reveals Nme6 and Nme7 are crucial for embryonic stem cell renewal
Q28511898A transducible nuclear/nucleolar protein, mLLP, regulates neuronal morphogenesis and synaptic transmission
Q41154841APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.
Q40370214APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome
Q38750052ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.
Q55345210Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy.
Q38011666Affinity-purification coupled to mass spectrometry: basic principles and strategies
Q90240762Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer
Q35932166An Association Rule Mining Approach to Discover lncRNAs Expression Patterns in Cancer Datasets
Q42376477An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells
Q38735200An essential step of kinetochore formation controlled by the SNARE protein Snap29.
Q35866218An extended γ-tubulin ring functions as a stable platform in microtubule nucleation.
Q48243869An improved toolbox to unravel the plant cellular machinery by tandem affinity purification of Arabidopsis protein complexes
Q34412323Analysis of candidate colitis genes in the Gdac1 locus of mice deficient in glutathione peroxidase-1 and -2.
Q34140627Analysis of the key elements of FFAT-like motifs identifies new proteins that potentially bind VAP on the ER, including two AKAPs and FAPP2.
Q36021806Analyzing Spindle Positioning Dynamics in Cultured Cells
Q33786311Anastral spindle assembly and γ-tubulin in Drosophila oocytes
Q50501117Arabidopsis GCP3-interacting protein 1/MOZART 1 is an integral component of the γ-tubulin-containing microtubule nucleating complex.
Q35865769Arabidopsis MZT1 homologs GIP1 and GIP2 are essential for centromere architecture
Q52364081Assembly and regulation of γ-tubulin complexes.
Q34760516Augmented annotation of the Schizosaccharomyces pombe genome reveals additional genes required for growth and viability
Q33351763Augmin plays a critical role in organizing the spindle and phragmoplast microtubule arrays in Arabidopsis
Q27306243Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission
Q30541252Augmin-dependent microtubule nucleation at microtubule walls in the spindle
Q37104867Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase
Q36252350Aurora B is regulated by acetylation/deacetylation during mitosis in prostate cancer cells
Q38102822Baculovirus expression: tackling the complexity challenge.
Q34308163Beyond hairballs: The use of quantitative mass spectrometry data to understand protein-protein interactions
Q26798315Building a ninefold symmetrical barrel: structural dissections of centriole assembly
Q37803036Building mitotic chromosomes
Q35084958Building protein-protein interaction networks with proteomics and informatics tools.
Q35837102Building the Microtubule Cytoskeleton Piece by Piece
Q27300705C11ORF24 is a novel type I membrane protein that cycles between the Golgi apparatus and the plasma membrane in Rab6-positive vesicles
Q37269065CD133 and Ki-67 expression is associated with gastrointestinal stromal tumor prognosis
Q39623295CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex.
Q93163176CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1
Q42828383Cell cycle-dependent expression of p42.3 promotes mitotic progression in malignant transformed cells
Q84111460Cell cycle: dissecting mitosis
Q21129300Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer
Q34218804Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly.
Q36210393Cep57, a NEDD1-binding pericentriolar material component, is essential for spindle pole integrity.
Q34294435Changes in Ect2 localization couple actomyosin-dependent cell shape changes to mitotic progression
Q33353348Characterization of the Arabidopsis augmin complex uncovers its critical function in the assembly of the acentrosomal spindle and phragmoplast microtubule arrays
Q39528462Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex.
Q30599549Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development
Q29871463Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
Q27322205Coiled-coil proteins facilitated the functional expansion of the centrosome
Q47035962Combined RNAi and localization for functionally dissecting long noncoding RNAs.
Q91430173Concerted expression of a cell cycle regulator and a metabolic enzyme from a bicistronic transcript in plants
Q57251751Conditional control of fluorescent protein degradation by an auxin-dependent nanobody
Q38893872Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling
Q53201872Connexin 32 is involved in mitosis.
Q36598924Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation
Q28478958Crenarchaeal CdvA forms double-helical filaments containing DNA and interacts with ESCRT-III-like CdvB
Q30002338Cyclebase 3.0: a multi-organism database on cell-cycle regulation and phenotypes
Q34170101DISC1 conditioned GWAS for psychosis proneness in a large Finnish birth cohort
Q28302106DISC1-binding proteins in neural development, signalling and schizophrenia
Q37903411DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond.
Q38960929Decoding sORF translation - from small proteins to gene regulation
Q28661079Deducing protein function by forensic integrative cell biology
Q30540291Deformations within moving kinetochores reveal different sites of active and passive force generation
Q52339047Degradation of a novel DNA damage response protein, tankyrase 1 binding protein 1 (Tab182), following adenovirus infection.
Q33644023Descriptive no more: the dawn of high-throughput microscopy
Q64244838Detecting Chromosome Instability in Cancer: Approaches to Resolve Cell-to-Cell Heterogeneity
Q48512394Development of a yeast internal-subunit eGFP labeling strategy and its application in subunit identification in eukaryotic group II chaperonin TRiC/CCT.
Q38429254Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome
Q84348730Discovering Mozart
Q92594995Dissecting the mechanisms of cell division
Q30653598Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint
Q58694254Dynamic regulation of dynein localization revealed by small molecule inhibitors of ubiquitination enzymes
Q47326376EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.
Q42230669EML4 promotes the loading of NUDC to the spindle for mitotic progression
Q34196887ESCRT machinery and cytokinesis: the road to daughter cell separation.
Q34972774Emerging Roles for SSeCKS/Gravin/AKAP12 in the Control of Cell Proliferation, Cancer Malignancy, and Barriergenesis
Q35917472Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing
Q37214262Expanding the Diversity of Imaging-Based RNAi Screen Applications Using Cell Spot Microarrays
Q59081843Experimental and computational framework for a dynamic protein atlas of human cell division.
Q42609623Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly
Q35009590Fodrin in centrosomes: implication of a role of fodrin in the transport of gamma-tubulin complex in brain
Q38625831Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase
Q37869837From RNAi screens to molecular function in embryonic stem cells.
Q37697834Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins
Q27021958GIP/MZT1 proteins orchestrate nuclear shaping
Q39602604GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR.
Q44028071Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding.
Q38328121Genome-wide repression of NF-κB target genes by transcription factor MIBP1 and its modulation by O-linked β-N-acetylglucosamine (O-GlcNAc) transferase
Q35436208Genomes, proteomes, and the central dogma
Q34646686Genomic imbalances in patients with a clinical presentation in the spectrum of Cornelia de Lange syndrome
Q50132795HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.
Q47140345HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development
Q64108464High Expression of Human AugminComplex Submit 3 Indicates Poor Prognosis and Associates with Tumor Progression in Hepatocellular Carcinoma
Q39615752High-throughput RNAi screening in mammalian cells with esiRNAs
Q41212579High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells
Q37843988How Förster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology
Q92932196How to use a multipurpose SNARE: The emerging role of Snap29 in cellular health
Q24338332Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance
Q40301090Increasing the precision of orthology-based complex prediction through network alignment.
Q35084945Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells
Q58749213Integrin and microtubule crosstalk in the regulation of cellular processes
Q35072528Interaction network of proteins associated with human cytomegalovirus IE2-p86 protein during infection: a proteomic analysis
Q42804398Interaction of p190A RhoGAP with eIF3A and Other Translation Preinitiation Factors Suggests a Role in Protein Biosynthesis.
Q37862657Isolation and characterization of plant protein complexes by mass spectrometry
Q36832518Isotope coded protein labeling coupled immunoprecipitation (ICPL-IP): a novel approach for quantitative protein complex analysis from native tissue
Q41523995Ki67 is a biological marker of malignant risk of gastrointestinal stromal tumors: A systematic review and meta-analysis
Q39188148LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells
Q39650780Lamina Associated Polypeptide 1 (LAP1) Interactome and Its Functional Features.
Q51131212Large-Scale Analysis of CRISPR/Cas9 Cell-Cycle Knockouts Reveals the Diversity of p53-Dependent Responses to Cell-Cycle Defects.
Q39451999Large-scale de novo prediction of physical protein-protein association
Q42589927Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads
Q66679494Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells
Q36293830Loss of apoptosis-inducing factor critically affects MIA40 function.
Q46812592MAG2 and three MAG2-INTERACTING PROTEINs form an ER-localized complex to facilitate storage protein transport in Arabidopsis thaliana
Q51228692MGO3 and GIP1 act synergistically for the maintenance of centromeric cohesion.
Q37513987MOZART1 and γ-tubulin complex receptors are both required to turn γ-TuSC into an active microtubule nucleation template
Q34332458Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele
Q38019685Mass spectrometry approaches to study mammalian kinase and phosphatase associated proteins
Q27938491Massively parallel measurements of molecular interaction kinetics on a microfluidic platform
Q37242379Mechanisms of Mitotic Spindle Assembly
Q90455007Microneedle manipulation of the mammalian spindle reveals specialized, short-lived reinforcement near chromosomes
Q30500006Micropilot: automation of fluorescence microscopy-based imaging for systems biology
Q47147267Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation
Q38092152Microtubule nucleation and establishment of the mitotic spindle in vascular plant cells
Q38575707Microtubule nucleation at the centrosome and beyond
Q37945020Microtubule nucleation by γ-tubulin complexes
Q57470882Microtubule nucleation by γ-tubulin complexes and beyond
Q30499170Microtubule stabilization in vivo by nucleation-incompetent γ-tubulin complex.
Q35636268Microtubules in plants
Q34292029Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis
Q41440478Mitotic Checkpoint Regulators Control Insulin Signaling and Metabolic Homeostasis
Q37728172Mitotic Spindle Assembly in Land Plants: Molecules and Mechanisms
Q38973298Mitotic spindle assembly in animal cells: a fine balancing act.
Q54978828Mitotic-Spindle Organizing Protein MztA Mediates Septation Signaling by Suppressing the Regulatory Subunit of Protein Phosphatase 2A-ParA in Aspergillus nidulans.
Q27675971Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex
Q30653286Molecular architecture and mechanism of the anaphase-promoting complex
Q26825961Moonlighting functions of the NRZ (mammalian Dsl1) complex
Q35954461Mutability and mutational spectrum of chromosome transmission fidelity genes
Q24301645Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture
Q29144881Mutations in the gene encoding IFT dynein complex component WDR34 cause Jeune asphyxiating thoracic dystrophy
Q37270598Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3(Alp6)
Q37208704NDE1 and NDEL1: twin neurodevelopmental proteins with similar 'nature' but different 'nurture'.
Q55384172NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization.
Q33811950NME7 is a functional component of the γ-tubulin ring complex
Q37715935NMR Characterization of Self-Association Domains Promoted by Interactions with LC8 Hub Protein.
Q38920403NUSAP1 expression is upregulated by loss of RB1 in prostate cancer cells
Q30703620Network analysis of GWAS data
Q36341303New insights into subcomplex assembly and modifications of centrosomal proteins
Q28730711Next-generation genomics: an integrative approach
Q34315255Next-generation proteomics: towards an integrative view of proteome dynamics.
Q24296940Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods
Q29871442NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function
Q41579479Nuclear envelope: a new frontier in plant mechanosensing?
Q47814413Nucleolar and spindle-associated protein 1 (NUSAP1) interacts with a SUMO E3 ligase complex during chromosome segregation
Q33669183Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells
Q30521431On the regulation, function, and localization of the DNA-dependent ATPase PICH.
Q99638526Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit
Q89702838Overexpression of SAPCD2 correlates with proliferation and invasion of colorectal carcinoma cells
Q36821619Overexpression of carbonic anhydrase II and Ki-67 proteins in prognosis of gastrointestinal stromal tumors
Q36865105Overexpression of p42.3 promotes cell growth and tumorigenicity in hepatocellular carcinoma
Q34199248PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution
Q92767866PICH and TOP3A cooperate to induce positive DNA supercoiling
Q55395928PPI network analyses of human WD40 protein family systematically reveal their tendency to assemble complexes and facilitate the complex predictions.
Q38232318Pericentriolar material structure and dynamics
Q89476598Personalized CT-based radiomics nomogram preoperative predicting Ki-67 expression in gastrointestinal stromal tumors: a multicenter development and validation cohort
Q35596008Pharmacological manipulation of transcription factor protein-protein interactions: opportunities and obstacles
Q47277307Phase Transitioning the Centrosome into a Microtubule Nucleator.
Q36090763Pivotal Role of AKAP12 in the Regulation of Cellular Adhesion Dynamics: Control of Cytoskeletal Architecture, Cell Migration, and Mitogenic Signaling
Q24329251Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis.
Q24299615Poc1A and Poc1B act together in human cells to ensure centriole integrity
Q36785209Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth.
Q37863285Processive ubiquitin chain formation by the anaphase-promoting complex.
Q60911613Profiling proliferative cells and their progeny in damaged murine hearts
Q26825374Prohibitin 2: At a communications crossroads
Q37038083Protein domain mapping by internal labeling and single particle electron microscopy
Q34450771Protein-protein interaction predictions using text mining methods
Q38715384Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells
Q31044616Proteomic data on the nuclear interactome of human MCM9.
Q36186917Proteomic profiling of ATM kinase proficient and deficient cell lines upon blockage of proteasome activity.
Q37153489Proteomics Analysis with a Nano Random Forest Approach Reveals Novel Functional Interactions Regulated by SMC Complexes on Mitotic Chromosomes
Q39332519Proteomics in Cell Division.
Q36884872Proteomics-based methods for discovery, quantification, and validation of protein-protein interactions
Q35251925Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes
Q48096114Quantitative Assessment of the Effects of Trypsin Digestion Methods on Affinity Purification-Mass Spectrometry-based Protein-Protein Interaction Analysis
Q37307416Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging.
Q39451744Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome
Q35673519Quantitative proteomic analysis shows differentially expressed HSPB1 in glioblastoma as a discriminating short from long survival factor and NOVA1 as a differentiation factor between low-grade astrocytoma and oligodendroglioma.
Q33861783Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions
Q38794957Quantitative proteomics reveals novel protein interaction partners of PP2A catalytic subunit in pancreatic β-cells
Q38071033Quantitative proteomics: A strategic ally to map protein interaction networks
Q41788699R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein
Q33903948RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity
Q33112709RED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint
Q26751202Recent advances in large-scale protein interactome mapping
Q39256977Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C).
Q91743833Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1
Q55545192RegenDbase: a comparative database of noncoding RNA regulation of tissue regeneration circuits across multiple taxa.
Q38919400Responses of chromosome segregation machinery to mechanical perturbations
Q41883102Rheology of the Active Cell Cortex in Mitosis
Q27008162Role of nucleation in cortical microtubule array organization: variations on a theme
Q57467603Roles of end-binding 1 protein and gamma-tubulin small complex in cytokinesis and flagella formation of Giardia lamblia
Q36187407SAMBA, a plant-specific anaphase-promoting complex/cyclosome regulator is involved in early development and A-type cyclin stabilization
Q43210731SHCBP1 is required for midbody organization and cytokinesis completion
Q58697513SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice
Q34806974SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs.
Q30418050Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol
Q35000662Shift in GATA3 functions, and GATA3 mutations, control progression and clinical presentation in breast cancer
Q38953772Silencing of STRN4 suppresses the malignant characteristics of cancer cells
Q38564174Size Scaling of Microtubule Assemblies in Early Xenopus Embryos
Q30414432Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling
Q38588713Spatial rule-based modeling: a method and its application to the human mitotic kinetochore
Q37411011Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis
Q37956288Structural insights into anaphase-promoting complex function and mechanism
Q41100050Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome
Q37811107Structure, function and mechanism of the anaphase promoting complex (APC/C).
Q85242680Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material
Q42112435Synergistic role of fission yeast Alp16GCP6 and Mzt1MOZART1 in γ-tubulin complex recruitment to mitotic spindle pole bodies and spindle assembly
Q37544007Synthetic genetic array screen identifies PP2A as a therapeutic target in Mad2-overexpressing tumors
Q41789354Systematic phosphorylation analysis of human mitotic protein complexes.
Q35189593Systems biology in immunology: a computational modeling perspective.
Q34954162Targeting RNA binding proteins involved in neurodegeneration
Q28771739Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis
Q35971862The APC/C Ubiquitin Ligase: From Cell Biology to Tumorigenesis
Q91802631The Centrosome and the Primary Cilium: The Yin and Yang of a Hybrid Organelle
Q36660304The Colossus of ubiquitylation: decrypting a cellular code
Q45327527The GCP3-interacting proteins GIP1 and GIP2 are required for γ-tubulin complex protein localization, spindle integrity, and chromosomal stability
Q37346646The GIP gamma-tubulin complex-associated proteins are involved in nuclear architecture in Arabidopsis thaliana
Q27310316The Msd1-Wdr8-Pkl1 complex anchors microtubule minus ends to fission yeast spindle pole bodies
Q35793424The Prediction and Validation of Small CDSs Expand the Gene Repertoire of the Smallest Known Eukaryotic Genomes.
Q41848433The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.
Q38232320The centrosome-Golgi apparatus nexus
Q28119161The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation
Q27020926The emerging roles of GPRC5A in diseases
Q37843675The function of spliceosome components in open mitosis
Q34313481The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8
Q92484085The interaction networks of the budding yeast and human DNA replication-initiation proteins
Q54979476The kinase domain of CK1 enzymes contains the localization cue essential for compartmentalized signaling at the spindle pole.
Q27331943The kinetochore protein Kis1/Eic1/Mis19 ensures the integrity of mitotic spindles through maintenance of kinetochore factors Mis6/CENP-I and CENP-A
Q30529809The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.
Q38137982The molecular basis for kinesin functional specificity during mitosis.
Q39876569The next frontier of systems biology: higher-order and interspecies interactions.
Q47259543The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes
Q34029652The phylogenomic analysis of the anaphase promoting complex and its targets points to complex and modern-like control of the cell cycle in the last common ancestor of eukaryotes
Q24604716The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics
Q57753489The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion
Q59092404The shieldin complex mediates 53BP1-dependent DNA repair
Q34172439The tandem affinity purification technology: an overview
Q38824687The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle.
Q33963929Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation
Q58798740Tissue-specific degradation of essential centrosome components reveals distinct microtubule populations at microtubule organizing centers
Q42256831Tombusvirus replication depends on Sec39p endoplasmic reticulum-associated transport protein
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