The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease

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The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M314160200
P698PubMed publication ID14747463

P50authorAlan T. RemaleyQ91944002
P2093author name stringAdele Cooney
Christian A Combs
Edward B Neufeld
John A Stonik
Stephen J Demosky
H Bryan Brewer
Silvia Santamarina-Fojo
Nancy Dwyer
Catherine L Knapper
Joan Blanchette-Mackie
Marcella Comly
P2860cites workMutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiencyQ22010457
The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathwayQ22010685
Apolipoprotein specificity for lipid efflux by the human ABCAI transporterQ24290771
Defective endocytic trafficking of NPC1 and NPC2 underlying infantile Niemann-Pick type C diseaseQ24293437
The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinctQ24554292
Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindredQ24652427
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1Q28141056
Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomesQ28589822
THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUMQ29391553
Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surfaceQ29547857
The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargoQ33856244
Late endosome motility depends on lipids via the small GTPase Rab7.Q34078419
How cells handle cholesterol.Q34094514
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.Q34827947
Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathwayQ35648656
Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier DiseaseQ35749982
Subcellular localization and activity of multidrug resistance proteinsQ39855198
The ABCA1 transporter functions on the basolateral surface of hepatocytesQ40700336
Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradationQ40738545
Evaluation of the role of phosphatidylserine translocase activity in ABCA1-mediated lipid effluxQ40744769
Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporterQ43517420
Cellular localization and trafficking of the human ABCA1 transporterQ43604836
Acid sphingomyelinase-deficient macrophages have defective cholesterol trafficking and effluxQ43752274
MLN64 mediates mobilization of lysosomal cholesterol to steroidogenic mitochondriaQ44031785
Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathwayQ44300047
The role of the ABCA1 transporter and cholesterol efflux in familial hypoalphalipoproteinemiaQ44406788
Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseasesQ47622411
Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient miceQ47888259
Abnormal processing of Golgi elements and lysosomes in Tangier diseaseQ70220055
Isolation and characterization of apolipoproteins A-I, A-II, and A-IVQ70295451
Intracellular trafficking of cholesterol monitored with a cyclodextrinQ71246519
Decreased reverse cholesterol transport from Tangier disease fibroblasts. Acceptor specificity and effect of brefeldin on lipid effluxQ73780280
Use of BODIPY-labeled sphingolipids to study membrane traffic along the endocytic pathwayQ74786177
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectApolipoprotein A1Q1316030
Tangier diseaseQ1442621
ATP binding cassette subfamily A member 1Q21115210
P304page(s)15571-8
P577publication date2004-04-09
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease
P478volume279