| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.BMCL.2009.02.126 |
| P698 | PubMed publication ID | 19307114 |
| P2093 | author name string | Ashley Parker | |
| Neil Moss | |||
| Heather Tye | |||
| Younggi Choi | |||
| Adam Flegg | |||
| Spencer Napier | |||
| Mark Whitaker | |||
| J Thomas Peterson | |||
| Derek Cogan | |||
| Donna Skow | |||
| Christopher Sarko | |||
| Andreas Kahrs | |||
| Josh Tomlinson | |||
| Orietta Meyn | |||
| Philip Ramsden | |||
| Pui Loke | |||
| Raj Nagaraja | |||
| P2860 | cites work | RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist | Q24672108 |
| Attenuation of haloperidol-induced catalepsy by a 5-HT2C receptor antagonist | Q24672386 | ||
| 5-HT(2B) receptors play a key role in mediating the excitatory effects of 5-HT in human colon in vitro | Q24673230 | ||
| Ablation of serotonin 5-HT(2B) receptors in mice leads to abnormal cardiac structure and function | Q28202523 | ||
| Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblasts | Q28276340 | ||
| Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice | Q28285608 | ||
| Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-kappaB in cardiomyocytes | Q34564767 | ||
| Functions of serotonin in hypoxic pulmonary vascular remodeling | Q34653768 | ||
| The importance of plasma protein binding in drug discovery | Q43851506 | ||
| Neurogenic dural protein extravasation induced by meta-chlorophenylpiperazine (mCPP) involves nitric oxide and 5-HT2B receptor activation | Q44326286 | ||
| Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy | Q44480703 | ||
| A simple method for predicting serum protein binding of compounds from IC(50) shift analysis for in vitro assays | Q47775437 | ||
| Altered expression of a limited number of genes contributes to cardiac decompensation during chronic ventricular tachypacing in dogs. | Q54567679 | ||
| The Emergence of Selective 5-HT2B Antagonists Structures, Activities and Potential Therapeutic Applications [General Reviews] | Q56551617 | ||
| Plasma protein binding affinity and its relationship to molecular structure: an in-silico analysis | Q79481932 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | 5-hydroxytryptamine receptor 2B | Q4639596 |
| pharmacokinetics | Q323936 | ||
| drug binding | Q14819373 | ||
| P304 | page(s) | 2206-10 | |
| P577 | publication date | 2009-04-15 | |
| P1433 | published in | Bioorganic & Medicinal Chemistry Letters | Q2709483 |
| P1476 | title | A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic properties | |
| P478 | volume | 19 |
| Q85090837 | Exploration of the binding of benzimidazole-biphenyl derivatives to hemoglobin using docking and molecular dynamics simulation |
| Q64951410 | Fingerprint-Based Machine Learning Approach to Identify Potent and Selective 5-HT2BR Ligands. |
| Q34659424 | Lorcaserin and adiposopathy: 5-HT2c agonism as a treatment for 'sick fat' and metabolic disease |
| Q48172109 | Structure-Based Scaffold Repurposing for G Protein-Coupled Receptors: Transformation of Adenosine Derivatives into 5HT2B/5HT2C Serotonin Receptor Antagonists |
| Q82676939 | The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery |
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