Association of CD2 and CD45 on human T lymphocytes

scientific article

Association of CD2 and CD45 on human T lymphocytes is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1042032889
P356DOI10.1038/345071A0
P698PubMed publication ID1970422

P2093author name stringB Schraven
S C Meuer
P Altevogt
Y Samstag
P2860cites workThe leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphataseQ24293046
Demonstration that the leukocyte common antigen CD45 is a protein tyrosine phosphataseQ24293361
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresisQ29547747
CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cellsQ33671680
CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokinesQ33838538
T cell stimulation via the erythrocyte receptor. Synergism between monoclonal antibodies and phorbol myristate acetate without changes of free cytoplasmic Ca++ levelsQ36351678
Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-SepharoseQ39218339
Antigen-like effects of monoclonal antibodies directed at receptors on human T cell clonesQ41833797
Phenomenon of human T cells rosetting with sheep erythrocytes analyzed with monoclonal antibodies. "Modulation" of a partially hidden epitope determining the conditions of interaction between T cells and erythrocytesQ42936146
Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complexQ42936415
Triggering of the alternative pathway of human T cell activation involves members of the T 200 family of glycoproteinsQ44090669
Activation of cytolytic T lymphocyte and natural killer cell function through the T11 sheep erythrocyte binding protein.Q54442697
An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor proteinQ58960509
Evidence that protein kinase C differentially regulates the human T lymphocyte CD2 and CD3 surface antigensQ69924446
P433issue6270
P407language of work or nameEnglishQ1860
P304page(s)71-4
P577publication date1990-05-03
P1433published inNatureQ180445
P1476titleAssociation of CD2 and CD45 on human T lymphocytes
P478volume345

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cites work (P2860)
Q52060267A comprehensive analysis of peripheral blood lymphocytes in healthy aged humans by flow cytometry.
Q41192475A fluorogenic assay of endogenous phosphatase for assessment of cell adhesion
Q34504342A functional complex is formed in human T lymphocytes between the protein tyrosine phosphatase CD45, the protein tyrosine kinase p56lck and pp32, a possible common substrate
Q73882481A multimeric form of soluble recombinant sheep LFA-3 (CD58) inhibits human T-cell proliferation
Q40774385A novel CD18 genomic deletion in a patient with severe leucocyte adhesion deficiency: a possible CD2/lymphocyte function-associated antigen-1 functional association in humans.
Q71704760APO-1(CD95)-mediated apoptosis in Jurkat cells does not involve src kinases or CD45
Q57911579Activation and internalization of p56lck upon CD45 triggering of Jurkat cells
Q68063440Activation and signaling status of human lamina propria T lymphocytes
Q41682723Activation of MAP-2 kinase activity by the CD2 receptor in Jurkat T cells can be reversed by CD45 phosphatase
Q41596145Activation of T cells through a T cell-specific epitope of CD45
Q72208040Alterations of CD2 association with T cell receptor signaling molecules in "CD2 unresponsive" human T lymphocytes
Q41519382Anti-T11.1 and -T11.2 monoclonal antibodies play a different role in CD2-mediated signal transduction.
Q40726410Apoptosis mediated through CD45 is independent of its phosphatase activity and association with leukocyte phosphatase-associated phosphoprotein
Q28568280Association of Src-like protein tyrosine kinases with the CD2 cell surface molecule in rat T lymphocytes and natural killer cells
Q30176114Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain.
Q28294016Association of the transmembrane 4 superfamily molecule CD53 with a tyrosine phosphatase activity
Q38336914Autonomous roles for the cytoplasmic domains of the CD2 and CD4 T cell surface antigens
Q35322962Biochemical analysis of MHC and non-MHC lymphocyte membrane antigens
Q41596633Both T cell receptor (TcR)-CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR-CD3-independent and CD45-dependent activation of p56lck
Q44705544CD3-Induced T-Cell Proliferation and Interleukin-2 Secretion is Modulated by the CD45 Antigen
Q49795518CD45 in human physiology and clinical medicine
Q67539010CD45 isoform expression during T cell development in the thymus
Q67531998CD45 modulates T cell receptor/CD3-induced activation of human thymocytes via regulation of tyrosine phosphorylation
Q72466163CD45 protein-tyrosine phosphatase is specifically associated with a 116-kDa tyrosine-phosphorylated glycoprotein
Q37110344CD45: a leukocyte-specific member of the protein tyrosine phosphatase family
Q41296604Characterization of the Interaction between CD45 and CD45-AP
Q67552465Comparison of the capacity of murine and human class I MHC molecules to stimulate T cell activation
Q37421949Coordinate interactions of protein tyrosine kinases and protein tyrosine phosphatases in T-cell receptor-mediated signalling
Q35237368Costimulatory signals for human T-cell activation induce nuclear translocation of pp19/cofilin.
Q44692111Decrease in number of CD16(LEU 11)+CD45RA(2H4)+ cells and defective production of natural killer cytotoxic factor in childhood acute lymphoblastic leukemia
Q72678147Defective CD2 T cell pathway activation in common variable immunodeficiency (CVID)
Q33938706Development and function of T cells in mice with a disrupted CD2 gene
Q74494551Differential immunosuppressive activity of monoclonal CD2 antibodies on allograft rejection versus specific antibody production
Q71930175Differential interaction of the CD2 extracellular and intracellular domains with the tyrosine phosphatase CD45 and the zeta chain of the TCR/CD3/zeta complex
Q53484244Disulfide trapping of protein complexes on the yeast surface.
Q68053981Does co-aggregation of the CD45 and CD3 antigens inhibit T cell antigen receptor complex-mediated activation of phospholipase C and protein kinase C?
Q68317612Down-regulation of protein kinase C activation in human lamina propria T lymphocytes: Influence of intestinal mucosa on T cell reactivity
Q30494156Dynamic regulation of CD45 lateral mobility by the spectrin-ankyrin cytoskeleton of T cells
Q71747901Enhanced production of IL4 but not of IFN gamma and IL 10 by peripheral blood mononuclear cells from atopic children in response to CD2 plus CD28 stimulation
Q67526186Ethanol-induced CD3 and CD2 hyporesponsiveness of peripheral blood T lymphocytes
Q72566294Ethanol-specific impairment of T-lymphocyte activation is caused by a transitory block in signal-transduction pathways
Q41433393Evidence for an association of CD45 with 32,000-33,000 MW phosphoproteins on murine T and B lymphocytes
Q41492337Evidence for cell surface association of CD2 and LFA-1 (CD11a/CD18) on T lymphocytes
Q41649370Expression of CD45 isoforms by Epstein-Barr virus-transformed human B lymphocytes
Q28270908Expression of different CD8 isoforms on distinct human lymphocyte subpopulations
Q43871858Four CD45/P56lck-associated phosphorproteins (pp29-pp32) undergo alterations in human T cell activation
Q27618481Functional glycan-free adhesion domain of human cell surface receptor CD58: design, production and NMR studies
Q67904588Functional properties of human lamina propria T lymphocytes assessed with mitogenic monoclonal antibodies
Q35125868Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
Q41522308Human CD38 is associated to distinct molecules which mediate transmembrane signaling in different lineages
Q67937056Human MHC Class I Antigens are Associated with a 90-kDa Cell Surface Protein
Q28273559Human T lymphocyte activation induces tyrosine phosphorylation of alpha-tubulin and its association with the SH2 domain of the p59fyn protein tyrosine kinase
Q41471367Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation
Q43812748Interaction of CD4:lck with the T cell receptor/CD3 complex induces early signaling events in the absence of CD45 tyrosine phosphatase
Q57965229Interactions of CD45-associated Protein with the Antigen Receptor Signaling Machinery in T-lymphocytes
Q52078248Isoform-specific associations of CD45 with accessory molecules in human T lymphocytes
Q35868451Isoforms of the CD45 common leukocyte antigen family: markers for human T-cell differentiation
Q41471767Isoforms of the transmembrane tyrosine phosphatase CD45 differentially affect T cell recognition.
Q36235220LAR tyrosine phosphatase receptor: alternative splicing is preferential to the nervous system, coordinated with cell growth and generates novel isoforms containing extensive CAG repeats
Q46678852Lamina propria T cell activation: role of the costimulatory molecule CD2 and its cytoplasmic tail for the regulation of proliferation and apoptosis
Q46161173Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase
Q73910725Linkage of the CCR5 Delta 32 mutation with a functional polymorphism of CD45RA
Q48097967Microglial tyrosine phosphorylation systems in normal and degenerating brain
Q74005044Microheterogeneity of the cell surface tyrosine phosphatase, CD45RA, on T cells: phytohaemagglutinin binding and non-binding fraction of the 220 kDa isoform
Q28287967Modulation of CD4 lateral interaction with lymphocyte surface molecules induced by HIV-1 gp120
Q77402478Molecular alterations of the Fyn-complex occur as late events of human T cell activation
Q28574573Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5
Q34339457Molecular associations involving CD16, CD45 and zeta and gamma chains on human natural killer cells
Q24312058Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes
Q40788287Molecular mechanisms mediating lymphocyte recirculation, inflammation, and metastasis formation
Q80670048Neutrophil function and molecular analysis in severe leukocyte adhesion deficiency type I without separation delay of the umbilical cord
Q36196185Ontogeny of the immune system and the invisible frontier to immune regulation
Q80506464Pas de deux
Q43462937Phenotypical and biochemical characterization of a variant CD45R expression pattern in human leukocytes
Q52105000Phosphotyrosine phosphatases are involved in reversion of T lymphoblastic proliferation.
Q72077887Physical association of CD5 and the T cell receptor/CD3 antigen complex on the surface of human T lymphocytes
Q30387550Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformatics
Q70664749Regulation of TCR signaling by CD45 lacking transmembrane and extracellular domains
Q41559108Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45.
Q71613574Reversal of hyporesponsiveness in lpr CD4-CD8- T cells is achieved by induction of cell cycling and normalization of CD2 and p59fyn expression
Q41098869Signaling via the CD2 receptor enhances HTLV-1 replication in T lymphocytes
Q67521052Signalling in human tumour infiltrating lymphocytes: the CD28 molecule is functional and is physically associated with the CD45R0 molecule
Q40790883Specific CD45 isoforms differentially regulate T cell receptor signaling
Q42805332Structural and functional epitopes of the human adhesion receptor CD58 (LFA-3).
Q42747570T cells of the human intestinal lamina propria are high producers of interleukin-10.
Q51985966The calcium response of human T lymphocytes is decreased in aging but increased in Alzheimer's dementia.
Q43487369The coexpression of CD45RA and CD45RO isoforms on T cells during the S/G2/M stages of cell cycle.
Q78109946The cytoplasmic and the transmembrane domains are not sufficient for class I MHC signal transduction
Q41255832The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation
Q41091144The human semaphorin-like leukocyte cell surface molecule CD100 associates with a serine kinase activity.
Q42816196The receptor function of CD2 in human CD2 transgenic mice is based on highly conserved associations with signal transduction molecules
Q40668323The regulation of B- and T-lymphocyte activation by the transmembrane protein tyrosine phosphatase CD45.
Q41332110The role of CD2 as a regulator of human T-cell cytokine production
Q41682334The role of CD45 and CD45-associated molecules in T cell activation
Q41610113The role of CD45 in signal transduction
Q40801710The role of p56lck and p59fyn tyrosine kinases and CD45 protein tyrosine phosphatase in T-cell development and clonal selection
Q40787122The self and the nonself: immunorecognition and immunologic functions
Q41745087The structure and function of CD26 in the T-cell immune response
Q41166734The structure and ligand interactions of CD2: implications for T-cell function
Q68311129The tyrosine kinase activity of p56lck is increased in human T cells activated via CD2
Q30194389Two-step TCR zeta/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases
Q102329058Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions
Q67959982Tyrosine phosphorylation in T-cell activation

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