Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

scientific article

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.271.32.19385
P3181OpenCitations bibliographic resource ID4844560
P698PubMed publication ID8702625
P5875ResearchGate publication ID14498972

P2093author name stringG Xia
M R Hayden
Y P Goldberg
R D Gietz
J G Hodgson
H B Koide
M A Kalchman
R K Graham
C M Pickart
K C Graham
P2860cites workA huntingtin-associated protein enriched in brain with implications for pathologyQ24303499
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's diseaseQ24316501
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neuronsQ24317574
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesQ24319848
Somatic mosaicism of CAG repeat in dentatorubral-pallidoluysian atrophy (DRPLA)Q71953329
Dynamics of ubiquitin conjugation during erythroid differentiation in vitroQ72167863
Dynamic mutations hit double figuresQ72586891
Ubiquitinated dystrophic neurites suggest corticospinal derangement in patients with amyotrophic lateral sclerosisQ72596779
The two-hybrid system: an assay for protein-protein interactionsQ72755047
Modes of DAPI banding and simultaneous in situ hybridizationQ72815252
Make it or break it: the role of ubiquitin-dependent proteolysis in cellular regulationQ75294324
Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individualsQ24324374
Abnormal gene product identified in hereditary dentatorubral–pallidoluysian atrophy (DRPLA) brainQ24324461
Induction of ubiquitin-conjugating enzymes during terminal erythroid differentiationQ24563013
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunitQ27860669
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.Q27860836
A novel genetic system to detect protein-protein interactionsQ27860915
UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation.Q27933109
High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clonesQ28274183
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotesQ28302701
Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated formQ28509836
Molecular cloning, expression and characterization of a ubiquitin conjugation enzyme (E2(17)kB) highly expressed in rat testisQ28580225
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53Q29547773
The ubiquitin system for protein degradationQ29614385
Degradation of CFTR by the ubiquitin-proteasome pathwayQ29616142
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27Q29617346
The ubiquitin-proteasome proteolytic pathwayQ29618638
Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascadeQ29620459
Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodiesQ33920421
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 geneQ34303468
Coordinated induction of the ubiquitin conjugation pathway accompanies the developmentally programmed death of insect skeletal muscleQ34308891
The N-end ruleQ35228520
The ubiquitin-conjugation systemQ35237882
Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteinsQ36695353
Interaction of the yeast RAD7 and SIR3 proteins: implications for DNA repair and chromatin structureQ36726627
When more is less: pathogenesis of glutamine repeat neurodegenerative diseasesQ40405315
Selective protein degradation: a journey's end within the proteasomeQ40410581
Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcriptQ41231403
Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugationQ41294965
Expression of the Huntington's disease (IT15) protein product in HD patientsQ41320790
Evidence from antibody studies that the CAG repeat in the Huntington disease gene is expressed in the proteinQ41364046
Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and sperm.Q42496337
Widespread expression of Huntington's disease gene (IT15) protein productQ42684112
Huntington's disease and repeating trinucleotidesQ45289986
Ubiquitin-reactive neurites in cerebral cortex of subjects with Huntington's chorea: a pathological correlate of dementia?Q45290935
CAG expansion affects the expression of mutant Huntingtin in the Huntington's disease brainQ45307352
Gametic and somatic tissue-specific heterogeneity of the expanded SCA1 CAG repeat in spinocerebellar ataxia type 1.Q45307587
Cerebral soluble ubiquitin is increased in patients with Alzheimer's diseaseQ48319206
Introducing DNA into Yeast by TransformationQ56341137
Rapid physical mapping of cloned DNA on banded mouse chromosomes by fluorescence in situ hybridizationQ67737800
Isolation of RNA using guanidinium saltsQ69005967
Murine erythroleukemia cells possess an active ubiquitin- and ATP-dependent proteolytic pathwayQ69350900
Quantitation and immunocytochemical localization of ubiquitin conjugates within rat red and white skeletal musclesQ69826165
P433issue32
P407language of work or nameEnglishQ1860
P921main subjectprotein ubiquitinationQ3547638
ubiquitin-dependent protein catabolic processQ14864233
Ubiquitin conjugating enzyme E2 KQ21109669
P304page(s)19385-94
P577publication date1996-08-09
P1433published inJournal of Biological ChemistryQ867727
P1476titleHuntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme
P478volume271