BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity

scientific article

BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/0008-5472.CAN-08-3355
P8608Fatcat IDrelease_hzmerzleqngeddkvehahsae2vu
P698PubMed publication ID19117993

P2093author name stringHiroyuki Nishikawa
Mamoru Fukuda
Tomohiko Ohta
Hiromichi Gomi
Wenwen Wu
Ayaka Koike
Ryoko Kojima
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectBRCA1 DNA repair associatedQ17487737
BRCA1 associated RING domain 1Q21100416
P304page(s)111-9
P577publication date2009-01-01
P1433published inCancer ResearchQ326097
P1476titleBRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity
P478volume69

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cites work (P2860)
Q33911349Ambiguous melanocytic tumors with loss of 3p21.
Q24599005An emerging model for BAP1's role in regulating cell cycle progression
Q24329078Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1
Q85236158BAP1 (BRCA1-associated protein 1) is a highly specific marker for differentiating mesothelioma from reactive mesothelial proliferations
Q47428787BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer
Q37221089BAP1 and cancer
Q104577032BAP1 binds BRCA1:BARD1 heterodimer
Q61124903BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation
Q37355644BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma
Q104577037BAP1 disrupts the BRCA1:BARD1 heterodimer
Q54669259BAP1 germline mutation in two first grade family members with uveal melanoma.
Q52568577BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma.
Q96430967BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice
Q24339530BAP1 is phosphorylated at serine 592 in S-phase following DNA damage
Q34280223BAP1 loss defines a new class of renal cell carcinoma
Q35591969BAP1 missense mutation c.2054 A>T (p.E685V) completely disrupts normal splicing through creation of a novel 5' splice site in a human mesothelioma cell line
Q35792362BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5.
Q90294125BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers
Q38545726BAP1, PBRM1 and SETD2 in clear-cell renal cell carcinoma: molecular diagnostics and possible targets for personalized therapies
Q33890512BAP1, a tumor suppressor gene driving malignant mesothelioma
Q37507563BRCA1 and its toolbox for the maintenance of genome integrity
Q90223367BRCA1-associated protein 1 expression and prognostic role in prostate adenocarcinoma
Q34353359Characterization of DNA hypermethylation in two cases of peritoneal mesothelioma
Q39515506Characterization of the gene structure, functional significance, and clinical application of RNF180, a novel gene in gastric cancer.
Q43806776Clinical and pathological impact of VHL, PBRM1, BAP1, SETD2, KDM6A, and JARID1c in clear cell renal cell carcinoma.
Q48326636Clinical significance of immunohistochemistry for detection of BAP1 mutations in uveal melanoma.
Q94474304DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer
Q38336126DUBs, the regulation of cell identity and disease
Q36502572Deubiquitinating enzyme BAP1 is involved in the formation and maintenance of the diapause embryos of Artemia
Q38843978Different prognostic roles of tumor suppressor gene BAP1 in cancer: A systematic review with meta-analysis
Q92421826Differential Expression of DNA Repair Genes in Prognostically-Favorable versus Unfavorable Uveal Melanoma
Q90575977Dissenting degradation: Deubiquitinases in cell cycle and cancer
Q27664221Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase
Q41574276Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma
Q24338634Erythroid differentiation-associated gene interacts with NPM1 (nucleophosmin/B23) and increases its protein stability, resisting cell apoptosis
Q47248762Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting Multiple Independent Domains.
Q26781153Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work
Q39399033Frequent inactivation of the BAP1 gene in epithelioid-type malignant mesothelioma
Q24601069Frequent mutation of BAP1 in metastasizing uveal melanomas
Q38870857Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cells
Q41084421Genes versus Environment: cytoplasmic BAP1 determines the toxic response to environmental stressors in mesothelioma
Q27671821Length of the active-site crossover loop defines the substrate specificity of ubiquitin C-terminal hydrolases for ubiquitin chains
Q58612052Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer
Q33698718Melanoma epidemiology, biology and prognosis
Q38146707Melanoma mutagenesis and aberrant cell signaling
Q33649025Molecular markers of paragangliomas/pheochromocytomas
Q90028615NUMB enhances Notch signaling by repressing ubiquitination of NOTCH intracellular domain
Q26770424New concepts on BARD1: Regulator of BRCA pathways and beyond
Q36205186New strategies in pleural mesothelioma: BAP1 and NF2 as novel targets for therapeutic development and risk assessment
Q36589947Ovarian cancer: in search of better marker systems based on DNA repair defects
Q38122565PBRM1 and BAP1 as novel targets for renal cell carcinoma
Q38646960Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma
Q40070779Panel sequencing of 264 candidate susceptibility genes and segregation analysis in a cohort of non-BRCA1, non-BRCA2 breast cancer families.
Q98647386Pathogenic germline variants in patients with features of hereditary renal cell carcinoma: evidence for further locus heterogeneity
Q37975137Pathological and molecular biological approaches to early mesothelioma
Q49698247Patterns of BAP1 protein expression provide insights into prognostic significance and the biology of uveal melanoma
Q38397568Prognostic significance of BRCA1-associated protein 1 in colorectal cancer
Q38120938Regulation of proteolysis by human deubiquitinating enzymes
Q49829001Role of BRCA Mutations in the Modulation of Response to Platinum Therapy
Q57755309Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesis
Q61812961Status Determines the Sensitivity of Malignant Mesothelioma Cells to Gemcitabine Treatment
Q38959150Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity
Q34496129The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer
Q37875478The BRCA1 ubiquitin ligase and homologous recombination repair
Q38214084The Importance of Multidisciplinary Approach in Early Detection of BAP1 Tumor Predisposition Syndrome: Clinical Management and Risk Assessment
Q90157623The association between the methylation frequency of BRCA1/2 gene promoter and occurrence and prognosis of breast carcinoma: A meta-analysis
Q37742632The biology of uveal melanoma
Q24323060The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.
Q39021700The epigenetic landscape of renal cancer
Q34769556The relative timing of mutations in a breast cancer genome
Q34564968The role of deubiquitinating enzymes in chromatin regulation.
Q28083152The roles of chromatin-remodelers and epigenetic modifiers in kidney cancer
Q24633127The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression
Q37474898Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
Q47592158Ubiquitin carboxyl-terminal hydrolases: involvement in cancer progression and clinical implications
Q47155655Ubiquitin recognition of BAP1: understanding its enzymatic function
Q47119023miR-31 Functions as an Oncomir Which Promotes Epithelial-Mesenchymal Transition via Regulating BAP1 in Cervical Cancer.