Dissection of a signaling pathway by which pathogen-associated molecular patterns recruit the JNK and p38 MAPKs and trigger cytokine release

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Dissection of a signaling pathway by which pathogen-associated molecular patterns recruit the JNK and p38 MAPKs and trigger cytokine release is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M703422200
P3181OpenCitations bibliographic resource ID841114
P698PubMed publication ID17584736

P2093author name stringJohn M Kyriakis
Jian Zhong
P2860cites workDirect activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.Q24292137
MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferationQ24299564
Activation of the SAPK pathway by the human STE20 homologue germinal centre kinaseQ24303413
Pathogen recognition and innate immunityQ27861084
TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase relatedQ28143924
Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunityQ28259757
Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]Q28280257
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signalingQ28513445
Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3Q28594813
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammationQ29614227
Molecular mechanisms of caspase regulation during apoptosisQ29617861
AP-1 function and regulationQ29618422
The Ste20 group kinases as regulators of MAP kinase cascadesQ29619312
TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathwayQ31858969
Signaling by the germinal center kinase family of protein kinasesQ33534707
Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascadesQ33758352
Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1.Q34379673
Mixed-lineage kinase control of JNK and p38 MAPK pathwaysQ34810173
p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcriptsQ34811464
The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation.Q35829153
A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76.Q36267208
Toll-like receptor signaling and atherosclerosisQ36433507
Intracellular pattern recognition receptors in the host responseQ36528528
Germinal center kinase is required for optimal Jun N-terminal kinase activation by Toll-like receptor agonists and is regulated by the ubiquitin proteasome system and agonist-induced, TRAF6-dependent stabilizationQ37527362
Role of activating protein-1 in the regulation of the vascular cell adhesion molecule-1 gene expression by tumor necrosis factor-alphaQ38339357
Tumor necrosis factor alpha-induced E-selectin expression is activated by the nuclear factor-kappaB and c-JUN N-terminal kinase/p38 mitogen-activated protein kinase pathwaysQ38349161
HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.Q41734011
A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinaseQ47987718
Essential function for the kinase TAK1 in innate and adaptive immune responsesQ50335551
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.Q54595193
TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunityQ62081996
Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-kappaB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2- and germinal center kinase related-dependent pathwayQ95802878
P433issue33
P407language of work or nameEnglishQ1860
P921main subjectpositive regulation of JNK cascadeQ14864950
Mitogen-activated protein kinase kinase kinase 10Q21133280
Mitogen-activated protein kinase kinase kinase kinase 2Q21158496
Mitogen-activated protein kinase kinase kinase 11Q21171701
P304page(s)24246-54
P577publication date2007-08-17
P1433published inJournal of Biological ChemistryQ867727
P1476titleDissection of a signaling pathway by which pathogen-associated molecular patterns recruit the JNK and p38 MAPKs and trigger cytokine release
P478volume282

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