A hyaluronidase activity of the sperm plasma membrane protein PH-20 enables sperm to penetrate the cumulus cell layer surrounding the egg

scientific article

A hyaluronidase activity of the sperm plasma membrane protein PH-20 enables sperm to penetrate the cumulus cell layer surrounding the egg is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.125.5.1157
P932PMC publication ID2120058
P698PubMed publication ID8195297
P5875ResearchGate publication ID277522356

P2093author name stringD G Myles
P Primakoff
Y Lin
K Mahan
W F Lathrop
P2860cites workBee venom hyaluronidase is homologous to a membrane protein of mammalian spermQ24563109
Molecular cloning of the human and monkey sperm surface protein PH-20Q24564510
cDNA cloning reveals the molecular structure of a sperm surface protein, PH-20, involved in sperm-egg adhesion and the wide distribution of its gene among mammalsQ24678675
The human sperm protein PH-20 has hyaluronidase activity.Q34347805
Sequence analysis and expression in Escherichia coli of the hyaluronidase gene of Streptococcus pyogenes bacteriophage H4489AQ35090787
Mouse gamete interactions during fertilization in vitro. Chlortetracycline as a fluorescent probe for the mouse sperm acrosome reactionQ36201030
Localized surface antigens of guinea pig sperm migrate to new regions prior to fertilizationQ36211169
A role for the migrating sperm surface antigen PH-20 in guinea pig sperm binding to the egg zona pellucidaQ36213868
Sperm exocytosis increases the amount of PH-20 antigen on the surface of guinea pig spermQ36215623
Evidence that proteolysis of the surface is an initial step in the mechanism of formation of sperm cell surface domainsQ36223973
Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large T antigenQ36895645
Complementarity between sperm surface beta-1,4-galactosyltransferase and egg-coat ZP3 mediates sperm-egg bindingQ38328115
Biochemistry of mammalian fertilizationQ39881296
Molecular events mediating sperm activationQ40856003
An ultrastructural study of epididymal mouse spermatozoa binding to zonae pellucidae in vitro: sequential relationship to the acrosome reactionQ41031225
Restricted lateral diffusion of PH-20, a PI-anchored sperm membrane proteinQ41437897
Binding of mouse spermatozoa to the zonae pellucidae of mouse eggs in cumulus: evidence that the acrosomes remain substantially intactQ41580664
Human sperm acrosome reaction-initiating activity associated with the human cumulus oophorus and mural granulosa cellsQ43820766
Evidence for plasma membrane impermeability to small ions in acrosome-intact mouse spermatozoa bound to mouse zonae pellucidae, using an aminoacridine fluorescent pH probe: time course of the zona-induced acrosome reaction monitored by both chlortetQ44892462
Localization and synthesis of hyaluronic acid in the cumulus cells and mural granulosa cells of the preovulatory follicleQ50792216
Binding of both acrosome-intact and acrosome-reacted guinea pig sperm to the zona pellucida during in vitro fertilization.Q53877592
A map of the guinea pig sperm surface constructed with monoclonal antibodies.Q53921016
Motile cells lacking hyaluronidase can penetrate the hamster oocyte cumulus complex.Q54277234
Mouse oocytes regulate hyaluronic acid synthesis and mucification by FSH-stimulated cumulus cellsQ68450070
Fully effective contraception in male and female guinea pigs immunized with the sperm protein PH-20Q68511629
Structure-activity studies of flavonoids as inhibitors of hyaluronidaseQ68865034
In vitro studies of the golden hamster sperm acrosome reaction: completion on the zona pellucida and induction by homologous soluble zonae pellucidaeQ68865164
Sperm-egg interactions in the mouse: sequence of events and induction of the acrosome reaction by a zona pellucida glycoproteinQ70426235
Mouse gamete interactions: the zona pellucida is the site of the acrosome reaction leading to fertilization in vitroQ70678513
Sperm penetration through oocyte investments in mammalsQ93655413
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmembrane proteinQ423042
binding of sperm to zona pellucidaQ14864901
Sperm adhesion molecule 1Q22677392
P304page(s)1157-63
P577publication date1994-06-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleA hyaluronidase activity of the sperm plasma membrane protein PH-20 enables sperm to penetrate the cumulus cell layer surrounding the egg
P478volume125

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cites work (P2860)
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