Mitochondrially localised MUL1 is a novel modulator of antiviral signaling

scientific article

Mitochondrially localised MUL1 is a novel modulator of antiviral signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/ICB.2013.7
P8608Fatcat IDrelease_bag6ps3hk5g6lgyzouubtrc7za
P698PubMed publication ID23399697
P5875ResearchGate publication ID235521651

P50authorNatalie A BorgQ45626069
Anthony J SadlerQ62748460
Ashley MansellQ37376445
Jing Jing KhooQ37841181
Paul J HertzogQ38359228
P2093author name stringDie Wang
Jodee Gould
Phillip Nagley
Kathryn Hjerrild
Kristie Jenkins
Rebecca Piganis
Belinda J Thomas
P2860cites workGenome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signalingQ21144354
Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathwayQ24292856
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunityQ24307162
Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriersQ24307457
GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growthQ24308802
Peroxisomes are signaling platforms for antiviral innate immunityQ24310723
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-IQ24312113
The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral responseQ24314946
The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradationQ24314976
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon inductionQ24318426
MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fissionQ24320331
SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.Q52174469
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virusQ24336255
STING is an endoplasmic reticulum adaptor that facilitates innate immune signallingQ24336398
GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVSQ24675888
Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate ImmunityQ27485306
Negative regulation of cytoplasmic RNA-mediated antiviral signalingQ27487296
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA virusesQ27860455
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3Q27861127
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activityQ28118562
VISA is an adapter protein required for virus-triggered IFN-beta signalingQ28131814
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathwaysQ28590675
Activators and target genes of Rel/NF-kappaB transcription factorsQ29547882
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunityQ29615913
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responsesQ29616349
Comparison of chicken 7SK and U6 RNA polymerase III promoters for short hairpin RNA expressionQ33306167
Virus-infection or 5'ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1Q33641410
NLRX1 is a regulator of mitochondrial antiviral immunityQ34737001
Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virusQ35197999
Triggering the innate antiviral response through IRF-3 activationQ36774934
MAVS dimer is a crucial signaling component of innate immunity and the target of hepatitis C virus NS3/4A proteaseQ37051657
MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.Q37433320
CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processesQ37448141
An additional role for SUMO in ubiquitin-mediated proteolysisQ37498263
SUMO and ubiquitin paths converge.Q37674654
Mitofusin 2 inhibits mitochondrial antiviral signalingQ39811050
The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathwaysQ40139227
Characterization and comparison of chicken U6 promoters for the expression of short hairpin RNAs.Q40197306
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradationQ40328896
Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.Q40348165
Transposon-based RNAi delivery system for generating knockdown cell linesQ40576535
Interferon regulatory factor-3-mediated activation of the interferon-sensitive response element by Toll-like receptor (TLR) 4 but not TLR3 requires the p65 subunit of NF-kappa.Q40626543
Mitochondrial membrane potential is required for MAVS-mediated antiviral signalingQ45285051
Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activityQ45345628
Transforming growth factor-beta enhances rhinovirus infection by diminishing early innate responsesQ45390581
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectnegative regulation of chemokine (C-C motif) ligand 5 productionQ21127352
Mitochondrial E3 ubiquitin protein ligase 1Q21131737
P304page(s)321-30
P577publication date2013-04-01
P1433published inImmunology & Cell BiologyQ13731918
P1476titleMitochondrially localised MUL1 is a novel modulator of antiviral signaling
P478volume91

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cites work (P2860)
Q49728023Comparative transcriptomics provides novel insights into the mechanisms of selenium tolerance in the hyperaccumulator plant Cardamine hupingshanensis
Q48059064Immunology and Cell Biology publication of the year awards 2013.
Q34042190Keeping the immune system in check: a role for mitophagy
Q38113765Mitochondria: sensors and mediators of innate immune receptor signaling.
Q40704434Mitochondrial E3 Ubiquitin Protein Ligase 1 Mediates Cigarette Smoke-Induced Endothelial Cell Death and Dysfunction.
Q89475475Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor protein
Q36040422Quantitative Proteomics Reveals the Roles of Peroxisome-associated Proteins in Antiviral Innate Immune Responses
Q61135039SUMO-mediated regulation of NLRP3 modulates inflammasome activity
Q48044040The Arabidopsis E3 Ubiquitin Ligase SP1 Targets to Chloroplasts, Peroxisomes, and Mitochondria.
Q35654526The Evolutionary History of MAPL (Mitochondria-Associated Protein Ligase) and Other Eukaryotic BAM/GIDE Domain Proteins
Q55384251The Role of Mitophagy in Innate Immunity.
Q38920441The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity.

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