scholarly article | Q13442814 |
P50 | author | Zhigang Li | Q42884334 |
P2093 | author name string | Narendra Thapa | |
Andrew C Hedman | |||
David B Sacks | |||
Richard A Anderson | |||
Suyong Choi | |||
P2860 | cites work | The effect of IQGAP1 on Xenopus embryonic ectoderm requires Cdc42 | Q74587695 |
IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling | Q77732943 | ||
An emerging role for IQGAP1 in regulating protein traffic | Q84286071 | ||
Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI | Q24292355 | ||
Type I PIPK-alpha regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation | Q24293175 | ||
IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner | Q24294255 | ||
IQGAP1 modulates activation of B-Raf | Q24309982 | ||
IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold | Q24312786 | ||
PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions | Q24314508 | ||
Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation | Q24318404 | ||
Phosphoinositide signaling regulates the exocyst complex and polarized integrin trafficking in directionally migrating cells | Q24602665 | ||
Scaffold proteins: hubs for controlling the flow of cellular information | Q24611517 | ||
Get to grips: steering local actin dynamics with IQGAPs | Q24645636 | ||
IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis | Q24655426 | ||
Critical role of PIP5KI{gamma}87 in InsP3-mediated Ca(2+) signaling | Q24676005 | ||
Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin | Q24683598 | ||
Cell migration: integrating signals from front to back | Q27860670 | ||
Phosphoinositides in cell regulation and membrane dynamics | Q27861051 | ||
Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion | Q27939824 | ||
IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin | Q28209157 | ||
Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170 | Q28213976 | ||
Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions | Q28214350 | ||
Elucidation of the interaction of calmodulin with the IQ motifs of IQGAP1 | Q28215755 | ||
IQGAP1 regulation and roles in cancer | Q28237517 | ||
Type Igamma661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis | Q28240831 | ||
IQGAP1: a key regulator of adhesion and migration | Q28250427 | ||
IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells | Q28256129 | ||
Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration | Q28295800 | ||
PIP2 and PIP3: complex roles at the cell surface | Q28609413 | ||
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate | Q28647599 | ||
Conserved microtubule-actin interactions in cell movement and morphogenesis | Q29615212 | ||
Cell adhesion: integrating cytoskeletal dynamics and cellular tension | Q29618066 | ||
The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors | Q30477995 | ||
Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes | Q30481021 | ||
Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes. | Q33584871 | ||
Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer. | Q33892896 | ||
IQGAP1 stimulates actin assembly through the N-WASP-Arp2/3 pathway | Q34579326 | ||
PIP(2) and proteins: interactions, organization, and information flow | Q34623576 | ||
PIP5KI gamma is required for cardiovascular and neuronal development | Q34645669 | ||
A screen for novel phosphoinositide 3-kinase effector proteins. | Q34751632 | ||
Phosphoinositide regulation of the actin cytoskeleton | Q35019759 | ||
IQGAP1 and its binding proteins control diverse biological functions | Q35713259 | ||
Regulation of microtubules in cell migration | Q36032502 | ||
Type I gamma phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migration | Q36118826 | ||
Plasma membrane phosphoinositide organization by protein electrostatics | Q36327803 | ||
IQGAP1 in cellular signaling: bridging the GAP. | Q36440667 | ||
Movin' on up: the role of PtdIns(4,5)P(2) in cell migration. | Q36450231 | ||
PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane | Q36630120 | ||
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. | Q36718374 | ||
A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family. | Q36761494 | ||
Regulation of the actin cytoskeleton by phosphatidylinositol 4-phosphate 5 kinases | Q36829577 | ||
Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting | Q37434355 | ||
Life at the leading edge | Q37894186 | ||
Phosphatidylinositol 4, 5 bisphosphate and the actin cytoskeleton | Q37989034 | ||
Phosphorylation of IQGAP1 modulates its binding to Cdc42, revealing a new type of rho-GTPase regulator | Q38336933 | ||
Involvement of IQGAP1, an effector of Rac1 and Cdc42 GTPases, in cell-cell dissociation during cell scattering | Q39458563 | ||
Rac controls PIP5K localisation and PtdIns(4,5)P₂ synthesis, which modulates vinculin localisation and neurite dynamics. | Q39655961 | ||
The PI(3,5)P2 and PI(4,5)P2 interactomes | Q39860903 | ||
Fibroblast adaptation and stiffness matching to soft elastic substrates | Q40787799 | ||
Binding of neomycin to phosphatidylinositol 4,5-bisphosphate (PIP2). | Q41268508 | ||
PIPKIγ regulates β-catenin transcriptional activity downstream of growth factor receptor signaling. | Q41818593 | ||
PI(4,5)P2-dependent microdomain assemblies capture microtubules to promote and control leading edge motility | Q42145207 | ||
Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration | Q42448806 | ||
IQGAP1 promotes cell motility and invasion | Q42798469 | ||
Localization of the PAK1-, WASP-, and IQGAP1-specifying regions of Cdc42. | Q42810090 | ||
A polybasic motif allows N-WASP to act as a sensor of PIP(2) density | Q45233508 | ||
Ras and Rho protein induction of motility and invasion in T47D breast adenocarcinoma cells. | Q53398246 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 19 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell migration | Q189092 |
P304 | page(s) | 2617-2630 | |
P577 | publication date | 2013-08-27 | |
P1433 | published in | The EMBO Journal | Q1278554 |
P1476 | title | IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration | |
P478 | volume | 32 |
Q92461144 | A nuclear phosphoinositide kinase complex regulates p53 |
Q30667347 | A resilient formin-derived cortical actin meshwork in the rear drives actomyosin-based motility in 2D confinement |
Q37636732 | A role for activated Cdc42 in glioblastoma multiforme invasion. |
Q38729859 | Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases. |
Q35948366 | Bioinformatic analyses in early host response to Porcine Reproductive and Respiratory Syndrome virus (PRRSV) reveals pathway differences between pigs with alternate genotypes for a major host response QTL |
Q38861831 | Control of diverse subcellular processes by a single multi-functional lipid phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2]. |
Q37579110 | HECTD1 controls the protein level of IQGAP1 to regulate the dynamics of adhesive structures |
Q97532061 | Hyperplasia suppressor gene inhibits the proliferation and metastasis of glioma cells by targeting rho family proteins |
Q55462178 | IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells. |
Q39294242 | IQGAP1 is a key node within the small GTPase network |
Q38629482 | IQGAP1 is a phosphoinositide effector and kinase scaffold |
Q51297968 | IQGAP1 makes PI(3)K signalling as easy as PIP, PIP2, PIP3. |
Q38367073 | IQGAP1: insights into the function of a molecular puppeteer |
Q35132297 | IQGAPs choreograph cellular signaling from the membrane to the nucleus |
Q36098641 | Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)? |
Q33738762 | PI(3,4)P2 plays critical roles in the regulation of focal adhesion dynamics of MDA-MB-231 breast cancer cells |
Q28083975 | PIP kinases define PI4,5P₂signaling specificity by association with effectors |
Q48144836 | PIPKIγ and talin couple phosphoinositide and adhesion signaling to control the epithelial to mesenchymal transition. |
Q50077060 | PLD and PA Take MT1-MMP for a Metastatic Ride. |
Q91962766 | Phosphatidic acid generated by PLD2 promotes the plasma membrane recruitment of IQGAP1 and neointima formation |
Q37348955 | Phosphatidylinositol phosphate 5-kinase Iγi2 in association with Src controls anchorage-independent growth of tumor cells. |
Q53971924 | Phosphoinositide 3-kinase pathways and autophagy require phosphatidylinositol phosphate kinases. |
Q47147567 | Ras GAP-related and C-terminal domain-dependent localization and tumorigenic activities of IQGAP1 in melanoma cells |
Q37391319 | The Hidden Conundrum of Phosphoinositide Signaling in Cancer |
Q95266089 | The Prediction and Prognostic Significance of INPP5K Expression in Patients with Liver Cancer |
Q93000654 | The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif |
Q27023065 | The biology of IQGAP proteins: beyond the cytoskeleton |
Q33830545 | The coordinating role of IQGAP1 in the regulation of local, endosome-specific actin networks |
Q59793515 | The phosphorylation status of PIP5K1C at serine 448 can be predictive for invasive ductal carcinoma of the breast |
Q92143850 | Type Iγ phosphatidylinositol phosphate kinase promotes tumor growth by facilitating Warburg effect in colorectal cancer |