Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy

scientific article

Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4161/AUTO.25413
P698PubMed publication ID24005319
P5875ResearchGate publication ID256448848

P50authorHeidi M McBrideQ57165442
P2093author name stringMichelangelo Campanella
Mirna Nascimento
Robert A Screaton
Stephen Baird
Valerie Lefebvre
Andy Cheuk-Him Ng
Qiujiang Du
P2860cites workPINK1 is selectively stabilized on impaired mitochondria to activate ParkinQ21145802
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesisQ22242250
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonismQ24309753
Parkin is recruited selectively to impaired mitochondria and promotes their autophagyQ24317471
Hereditary early-onset Parkinson's disease caused by mutations in PINK1Q24337084
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagyQ24339224
Fission and selective fusion govern mitochondrial segregation and elimination by autophagyQ24652230
Mitochondrial DNA mutations in human diseaseQ24676881
Mitochondrial AAA proteases--towards a molecular understanding of membrane-bound proteolytic machinesQ26858909
Mechanisms of mitophagyQ27310261
The structure of bovine F1-ATPase in complex with its regulatory protein IF1Q27641847
How the regulatory protein, IF1, inhibits F1-ATPase from bovine mitochondriaQ27648517
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's diseaseQ28292932
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1Q28510145
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkinQ29547423
Chronic systemic pesticide exposure reproduces features of Parkinson's diseaseQ29614763
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusinQ29615625
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkinQ29615684
PINK1-dependent recruitment of Parkin to mitochondria in mitophagyQ29620567
DJ-1 is critical for mitochondrial function and rescues PINK1 loss of functionQ30495575
Assembly and oligomerization of human ATP synthase lacking mitochondrial subunits a and A6L.Q33534929
Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and agingQ34556311
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamicsQ34621634
Mitochondria, oxidative metabolism and cell death in strokeQ35002708
Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potentialQ35406465
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitmentQ35874914
Rows of ATP synthase dimers in native mitochondrial inner membranes.Q36008746
Targeting mitochondria for neuroprotection in Parkinson's diseaseQ37974311
Functional F1-ATPase essential in maintaining growth and membrane potential of human mitochondrial DNA-depleted rho degrees cellsQ38550417
The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative responseQ39395452
Protonic inhibition of the mitochondrial adenosine 5'-triphosphatase in ischemic cardiac muscle. Reversible binding of the ATPase inhibitor protein to the mitochondrial ATPase during ischemiaQ41356864
Binding of the inhibitor protein IF(1) to bovine F(1)-ATPase.Q42616863
Excessive ATP hydrolysis in ischemic myocardium by mitochondrial F1F0-ATPase: effect of selective pharmacological inhibition of mitochondrial ATPase hydrolase activityQ45061648
Regulation of mitochondrial structure and function by the F1Fo-ATPase inhibitor protein, IF1.Q46510055
Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fissionQ47197847
Apoptosis and necrosis: intracellular ATP level as a determinant for cell death modesQ47956069
The inhibitor protein (IF1) promotes dimerization of the mitochondrial F1F0-ATP synthaseQ50475025
Quantitation and origin of the mitochondrial membrane potential in human cells lacking mitochondrial DNA.Q50519005
Parkinson's disease in a chemist working with 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridineQ64764588
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectATP synthase inhibitory factor subunit 1Q21106657
positive regulation of autophagy of mitochondrion in response to mitochondrial depolarizationQ24493763
P304page(s)1770-1779
P577publication date2013-08-07
P1433published inAutophagyQ1255295
P1476titleGenome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy
P478volume9

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cites work (P2860)
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Q42204560Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis.
Q52884777[Role of mitophagy in the mitochondrial quality control].

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