The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis

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The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.25.6.2395-2405.2005
P932PMC publication ID1061619
P698PubMed publication ID15743832

P50authorKelli L. BoydQ116621330
Monica CardoneQ130293214
P2093author name stringJonas A Nilsson
John L Cleveland
Ugur Ozbek
Ayten Kandilci
Gerard C Grosveld
Cintia Carella
Jennifer A Brennan
Sema Sirma
P2860cites workTEL is a sequence-specific transcriptional repressorQ22010632
Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissues and can associate with TEL1/ETV6Q22254171
Tel-2 is a novel transcriptional repressor related to the Ets factor Tel/ETV-6Q24290595
Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TELQ28592571
Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesisQ28593886
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalizationQ29614701
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARFQ29619663
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.Q33889383
Characterization of a novel ETS gene, TELB, encoding a protein structurally and functionally related to TEL.Q33921480
Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophagesQ33933240
Proteins of the ETS family with transcriptional repressor activityQ34139422
Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinomaQ34160782
Molecular biology of the Ets family of transcription factorsQ34174026
Transcriptional regulation of the bcl-x gene encoding the anti-apoptotic Bcl-xL protein by Ets, Rel/NFkappaB, STAT and AP1 transcription factor familiesQ34238502
Apoptosis and chemoresistance in transgenic cancer modelsQ34563810
Cell cycle deregulation in B-cell lymphomas.Q34977269
The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrowQ35206654
Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesisQ35208288
INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.Q35208402
bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice.Q36366215
Distinct roles for E2F proteins in cell growth control and apoptosisQ36653915
Expression of the c-myc oncogene under control of an immunoglobulin enhancer in E mu-myc transgenic miceQ36838691
High frequency of t(12;21) in childhood B-lineage acute lymphoblastic leukemia.Q38288856
Pi 1 binding sites are negative regulators of bcl-2 expression in pre-B cellsQ40016702
Tel, a frequent target of leukemic translocations, induces cellular aggregation and influences expression of extracellular matrix components.Q40452513
A breakpoint map of recurrent chromosomal rearrangements in human neoplasiaQ40899125
The TEL gene contributes to the pathogenesis of myeloid and lymphoid leukemias by diverse molecular genetic mechanisms.Q41431729
Establishment of a reproducible culture technique for the selective growth of B-cell progenitorsQ41647602
Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.Q41714456
TEL, a putative tumor suppressor, induces apoptosis and represses transcription of Bcl-XL.Q42796261
The leukemia-associated gene TEL encodes a transcription repressor which associates with SMRT and mSin3A.Q42809374
TEL2, an ETS factor expressed in human leukemia, regulates monocytic differentiation of U937 Cells and blocks the inhibitory effect of TEL1 on ras-induced cellular transformationQ42825938
Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo.Q43459895
The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemiaQ47335313
Ets transcription factors and human diseaseQ48027304
Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locusQ48393487
Chromosomal translocations in human cancer.Q52512616
Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.Q52526599
Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss.Q53380068
High resolution mapping of chromosome 6 deletions in cervical cancer.Q53422516
DNA damage responses and chemosensitivity in the E mu-myc mouse lymphoma model.Q53929522
p14ARF links the tumour suppressors RB and p53.Q55067966
The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic miceQ57338720
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic miceQ57338722
Differential expression of the translocated and the untranslocated c-myc oncogene in Burkitt lymphomaQ70449918
Synergy between a human c-myc transgene and p53 null genotype in murine thymic lymphomas: contrasting effects of homozygous and heterozygous p53 lossQ72245131
Changes in DNA copy number in primary gastric carcinomas by comparative genomic hybridizationQ77554585
Widespread chromosomal abnormalities in high-grade ductal carcinoma in situ of the breast. Comparative genomic hybridization study of pure high-grade DCISQ77976509
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)2395-405
P577publication date2005-03-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleThe novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis
P478volume25

Reverse relations

cites work (P2860)
Q36561755Clinical significance of high c-MYC and low MYCBP2 expression and their association with Ikaros dysfunction in adult acute lymphoblastic leukemia
Q38940069Cooperative interactions between p53 and NFκB enhance cell plasticity.
Q41224538Downregulation of Friend Leukemia Virus Integration 1 as a Feedback Mechanism That Restrains Lipopolysaccharide Induction of Matrix Metalloproteases and Interleukin-10 in Human Macrophages
Q58745901ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer
Q58416369ETV7-Mediated DNAJC15 Repression Leads to Doxorubicin Resistance in Breast Cancer Cells
Q93382524Establishment of a transgenic mouse to model ETV7 expressing human tumors
Q92106885Global Transcriptome Profiling of Multiple Porcine Organs Reveals Toxoplasma gondii-Induced Transcriptional Landscapes
Q41903687Identifying new targets in leukemogenesis using computational approaches
Q35729943Ink4a and Arf are crucial factors in the determination of the cell of origin and the therapeutic sensitivity of Myc-induced mouse lymphoid tumor.
Q34631634MN1 overexpression is an important step in the development of inv(16) AML.
Q24669642MN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in mice
Q53344487MN1-TEL, the product of the t(12;22) in human myeloid leukemia, immortalizes murine myeloid cells and causes myeloid malignancy in mice.
Q34692292Mapping of MN1 sequences necessary for myeloid transformation
Q34972364Myc roles in hematopoiesis and leukemia
Q39728196PRL-2 increases Epo and IL-3 responses in hematopoietic cells
Q36800430Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions
Q37620148Polycomb group proteins: navigators of lineage pathways led astray in cancer
Q24647331Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyperproliferation and restores myeloid differentiation
Q35915972SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice
Q36557268TEL2 suppresses metastasis by down-regulating SERPINE1 in nasopharyngeal carcinoma
Q35850023The ETS factor TEL2 is a hematopoietic oncoprotein
Q34555986The ETS family of oncogenic transcription factors in solid tumours.
Q41929611Zebrafish ETV7 regulates red blood cell development through the cholesterol synthesis pathway

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