The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis

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The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis is …
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scholarly articleQ13442814

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P356DOI10.1172/JCI23559
P8608Fatcat IDrelease_4qaahobwrfg33idsh7s6kkape4
P3181OpenCitations bibliographic resource ID1627289
P932PMC publication ID1172228
P698PubMed publication ID16007267

P50authorArmin SchneiderQ30764723
Hans-Georg KuhnQ56441816
Walter MierQ88713133
Martin HasselblattQ39062301
Martin MaurerQ43105102
P2093author name stringStefan Schwab
Nikolaus Gassler
Rico Laage
Wolf-Rüdiger Schäbitz
Rainer Kollmar
Jaroslaw Aronowski
Alfred Bach
Daniela Weber
Clemens Sommer
Carola Krüger
Tobias Steigleder
Claudia Pitzer
P2860cites workDoublecortin is a microtubule-associated protein and is expressed widely by migrating neuronsQ28139253
Induction of neurogenesis in the neocortex of adult miceQ28139868
Theta band oscillation and synchrony in the hippocampal formation and associated structures: the case for its role in sensorimotor integrationQ28206701
Transient expression of doublecortin during adult neurogenesisQ28212071
Induction of reproducible brain infarction by photochemically initiated thrombosisQ28235221
NeuN, a neuronal specific nuclear protein in vertebratesQ28510657
Cloning and characterization of the 5'-flanking region of the rat neuron-specific Class III beta-tubulin geneQ28580697
Programmed cell death of adult-generated hippocampal neurons is mediated by the proapoptotic gene BaxQ28585790
Regulation of neuronal survival by the serine-threonine protein kinase AktQ29614185
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrusQ29615348
Neuronal replacement from endogenous precursors in the adult brain after strokeQ29615772
Neuroprotective effect of granulocyte colony-stimulating factor after focal cerebral ischemia.Q31134470
Enhanced neurogenesis after transient global ischemia in the dentate gyrus of the rat.Q32174329
Granulocyte colony-stimulating factor induces ERK5 activation, which is differentially regulated by protein-tyrosine kinases and protein kinase C. Regulation of cell proliferation and survivalQ33940371
Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamusQ33954181
Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1 beta and tumor necrosis factor-alphaQ48427106
Impaired adult neurogenesis in mice lacking the transcription factor E2F1.Q48459656
Granulocyte-macrophage colony-stimulating factor crosses the blood--brain and blood--spinal cord barriersQ48586998
Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells.Q48692503
Detection of cytokine mRNA in astrocyte cultures using the polymerase chain reactionQ68459611
Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony-stimulating factorsQ68799816
Granulocyte colony-stimulating factor activation of Stat3 alpha and Stat3 beta in immature normal and leukemic human myeloid cellsQ71611719
Characterization of a serum factor stimulating the differentiation of myelomonocytic leukemic cellsQ72090049
Behavioral deficits following experimental subarachnoid hemorrhage in the ratQ72897496
CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injuryQ73503153
Effects of colony-stimulating factors (CSFs) on neutrophil apoptosis: possible roles at inflammation siteQ73643355
Cortical neurogenesis in adult rats after reversible photothrombotic strokeQ74195845
Analysis of neurogenesis and programmed cell death reveals a self-renewing capacity in the adult rat brainQ74233473
Functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem cellsQ80593656
Direct stimulation of adult neural stem cells in vitro and neurogenesis in vivo by vascular endothelial growth factorQ80783829
Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factorQ34049948
Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulbQ34067026
Bcl-2 family gene products in cerebral ischemia and traumatic brain injuryQ34076414
An overview of acute stroke therapy: past, present, and futureQ34087892
Neurotrophins use the Erk5 pathway to mediate a retrograde survival response.Q34090264
Purification and biochemical characterization of human pluripotent hematopoietic colony-stimulating factorQ34192924
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathwayQ34278037
Analysis of serial measurements in medical researchQ35167613
Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the ratQ35298897
Proliferation, differentiation, and long-term culture of primary hippocampal neuronsQ36253429
Coexpression of neurotrophins and their receptors in neurons of the central nervous systemQ36427306
Reperfusion injury: demonstration of brain damage produced by reperfusion after transient focal ischemia in ratsQ36888097
Erythropoietin crosses the blood-brain barrier to protect against experimental brain injuryQ37250532
Filgrastim. A review of its pharmacological properties and therapeutic efficacy in neutropeniaQ40397077
Activation of Akt kinase by granulocyte colony-stimulating factor (G-CSF): evidence for the role of a tyrosine kinase activity distinct from the Janus kinases.Q40898197
Use-dependent structural events in recovery of functionQ41261889
Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosisQ41748320
Functional connectivity between the red nucleus and the hippocampus supports the role of hippocampal formation in sensorimotor integrationQ42462532
A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside.Q42536958
Beneficial effect of pharmacological mobilization of bone marrow in experimental cerebral ischemiaQ42691824
Directed migration of neuronal precursors into the ischemic cerebral cortex and striatumQ42835101
Extracellular signal-regulated protein kinase (ERK)-dependent and ERK-independent pathways target STAT3 on serine-727 in human neutrophils stimulated by chemotactic factors and cytokinesQ42994196
Cortical neurogenesis in adult rats after transient middle cerebral artery occlusionQ43599424
Zn2+-induced ERK activation mediated by reactive oxygen species causes cell death in differentiated PC12 cellsQ43694502
N-methyl-D-aspartate receptor-mediated increase of neurogenesis in adult rat dentate gyrus following strokeQ43698114
Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous systemQ43845852
Long-term survival and cell death of newly generated neurons in the adult rat olfactory bulbQ44216003
Theta- and movement velocity-related firing of hippocampal neurons is disrupted by lesions centered on the perirhinal cortexQ44354678
Short-term and long-term survival of new neurons in the rat dentate gyrusQ44419578
Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesisQ44465567
Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel runningQ44626424
VEGF is necessary for exercise-induced adult hippocampal neurogenesisQ44680412
Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils.Q46341741
Migration patterns of subventricular zone cells in adult mice change after cerebral cortex injuryQ47294785
Restriction-mediated differential display (RMDD) identifies pip92 as a pro-apoptotic gene product induced during focal cerebral ischemiaQ48026245
Effect of brain-derived neurotrophic factor treatment and forced arm use on functional motor recovery after small cortical ischemiaQ48027101
Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways.Q48267353
Behavioral transitions modulate hippocampal electroencephalogram correlates of open field behavior in the rat: support for a sensorimotor function of hippocampal rhythmical synchronous activity.Q48354400
P4510describes a project that usesImageJQ1659584
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectneurogenesisQ1456827
cell deathQ2383867
P304page(s)2083-2098
P577publication date2005-07-07
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleThe hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis
P478volume115

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cites work (P2860)
Q58547418A New Approach to Cerebral Palsy Treatment: Discussion of the Effective Components of Umbilical Cord Blood and its Mechanisms of Action
Q48189448A neuroprotective function for the hematopoietic protein granulocyte-macrophage colony stimulating factor (GM-CSF).
Q36971669A novel combinatorial therapy with pulp stem cells and granulocyte colony-stimulating factor for total pulp regeneration
Q48818770A novel flow cytometry-based technique to measure adult neurogenesis in the brain
Q45947469A pilot cohort study of granulocyte colony-stimulating factor in the treatment of unresponsive thin endometrium resistant to standard therapies.
Q35887444A possible role for the immune system in adult neurogenesis: new insights from an invertebrate model
Q33933699A screen for peptide agonists of the G-CSF receptor
Q36655337Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease
Q38779620Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration
Q38302511Adjuvant granulocyte colony-stimulating factor therapy results in improved spatial learning and stimulates hippocampal neurogenesis in a mouse model of pneumococcal meningitis.
Q43466093Aging aggravates ischemic stroke-induced brain damage in mice with chronic peripheral infection.
Q36903124An early granulocyte colony-stimulating factor treatment attenuates neuropathic pain through activation of mu opioid receptors on the injured nerve
Q33260756An extended window of opportunity for G-CSF treatment in cerebral ischemia
Q42046756Anti-apoptotic effect of granulocyte-colony stimulating factor after focal cerebral ischemia in the rat.
Q39056339Anti-colony-stimulating factor therapies for inflammatory and autoimmune diseases
Q33943588Anti-neutrophil antibody enhances the neuroprotective effects of G-CSF by decreasing number of neutrophils in hypoxic ischemic neonatal rat model
Q93075906Antiapoptotic Effect of Granulocyte-Colony Stimulating Factor After Peripheral Nerve Trauma
Q36297305Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia
Q44788657Assessing olfactory functions in patients with Barth syndrome
Q34036456Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells
Q92119058Autologous cord blood in children with cerebral palsy: a review
Q27026889Autonomic nervous system and immune system interactions
Q59808726Biomarker Supervised G-CSF (Filgrastim) Response in ALS Patients
Q47935377Bone marrow drives central nervous system regeneration after radiation injury.
Q37447090Bone marrow-derived mononuclear cells do not exert acute neuroprotection after stroke in spontaneously hypertensive rats
Q36804531Bone marrow-derived stem cells in neurological diseases: stones or masons?
Q37214453Both systemic and local application of granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy.
Q38900723CD114: A New Member of the Neural Crest-Derived Cancer Stem Cell Marker Family
Q36023980CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo.
Q34556952CNS-targeted viral delivery of G-CSF in an animal model for ALS: improved efficacy and preservation of the neuromuscular unit
Q91707651Cancer Stem Cells and Neuroblastoma: Characteristics and Therapeutic Targeting Options
Q92193226Cancer stem cells in neuroblastoma therapy resistance
Q35459801Cell biology and clinical promise of G-CSF: immunomodulation and neuroprotection
Q83825682Cell therapy for ischaemic stroke
Q48403988Cell type specific signalling by hematopoietic growth factors in neural cells
Q34547149Cellular players of hematopoietic stem cell mobilization in the bone marrow niche.
Q49700133Changes in the secretome of tri-dimensional spheroid-cultured human mesenchymal stem cells in vitro by interleukin-1 priming.
Q97543439Characterization of G-CSF receptor expression in medulloblastoma
Q27305612Chemotactic and inflammatory responses in the liver and brain are associated with pathogenesis of Rift Valley fever virus infection in the mouse
Q48371870Cognitive impairment in heart failure: A protective role for angiotensin-(1-7).
Q24201855Colony stimulating factors (including erythropoietin, granulocyte colony stimulating factor and analogues) for stroke
Q24245166Colony stimulating factors (including erythropoietin, granulocyte colony stimulating factor and analogues) for stroke
Q24245243Colony stimulating factors (including erythropoietin, granulocyte colony stimulating factor and analogues) for stroke
Q52588556Combination of G-CSF administration and human amniotic fluid mesenchymal stem cell transplantation promotes peripheral nerve regeneration.
Q34409696Combination therapy of human umbilical cord blood cells and granulocyte colony stimulating factor reduces histopathological and motor impairments in an experimental model of chronic traumatic brain injury
Q39747076Combined effects of hematopoietic progenitor cell mobilization from bone marrow by granulocyte colony stimulating factor and AMD3100 and chemotaxis into the brain using stromal cell-derived factor-1α in an Alzheimer's disease mouse model
Q38618826Control of Cell Survival in Adult Mammalian Neurogenesis
Q37663926Cytokine therapy-mediated neuroprotection in a Friedreich's ataxia mouse model
Q31143549Development of new stroke therapies: outlook for neuroprotective drugs
Q47386342Differential regulation of NSC phenotype and genotype by chronically activated microglia within cocultures
Q27319805Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip
Q44888340Distribution of the hematopoietic growth factor G-CSF and its receptor in the adult human brain with specific reference to Alzheimer's disease
Q35780806Duchenne muscular dystrophy: current cell therapies
Q34726647Dynamic and extensive metabolic state-dependent regulation of cytokine expression and circulating levels
Q35973656Effect of granulocyte-colony stimulating factor on expression of selected proteins involved in regulation of apoptosis in the brain of newborn piglets after cardiopulmonary bypass and deep hypothermic circulatory arrest
Q55033159Effect of human recombinant granulocyte colony-stimulating factor on rat busulfan-induced testis injury.
Q91607175Effect of the HDAC Inhibitor, Sodium Butyrate, on Neurogenesis in a Rat Model of Neonatal Hypoxia-Ischemia: Potential Mechanism of Action
Q41181881Effects of an Inhibitor of Monocyte Recruitment on Recovery from Traumatic Brain Injury in Mice Treated with Granulocyte Colony-Stimulating Factor.
Q34319576Efficacy of granulocyte-colony stimulating factor treatment in a rat model of anterior ischemic optic neuropathy
Q110597015Elevated granulocyte-colony stimulating factor and hematopoietic stem cell mobilization in Niemann-Pick Type C1 disease
Q98473609Emerging Therapeutic Strategies for Traumatic Spinal Cord Injury
Q38100263Emerging neuroprotective drugs for the treatment of acute ischaemic stroke
Q48602534Endogenous granulocyte colony-stimulating factor: a biomarker in acute ischemic stroke
Q36872684Endotoxemia-induced cytokine-mediated responses of hippocampal astrocytes transmitted by cells of the brain-immune interface
Q41907097Enhanced and Secretory Expression of Human Granulocyte Colony Stimulating Factor by Bacillus subtilis SCK6.
Q51767535Enhancing endogenous capacity to repair a stroke-damaged brain: An evolving field for stroke research.
Q35620417Expression of brain derived-neurotrophic factor and granulocyte-colony stimulating factor in the urothelium: relation with voiding function.
Q39570530Expression of granulocyte colony stimulating factor and its receptor by retinal pigment epithelial cells: a role in maintaining differentiation-competent state.
Q42835958Expression of granulocyte colony-stimulating factor 3 receptor in the spinal dorsal horn following spinal nerve ligation-induced neuropathic pain.
Q39003470Extracellular molecules in hematopoietic stem cell mobilisation
Q38977037Fractone-heparan sulphates mediate FGF-2 stimulation of cell proliferation in the adult subventricular zone
Q35890570Functional Improvement after Photothrombotic Stroke in Rats Is Associated with Different Patterns of Dendritic Plasticity after G-CSF Treatment and G-CSF Treatment Combined with Concomitant or Sequential Constraint-Induced Movement Therapy
Q90629399G-CSF (filgrastim) treatment for amyotrophic lateral sclerosis: protocol for a phase II randomised, double-blind, placebo-controlled, parallel group, multicentre clinical study (STEMALS-II trial)
Q35752008G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation.
Q38892537G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease.
Q61081210G-CSF Receptor Structure, Function, and Intracellular Signal Transduction
Q41185045G-CSF administration attenuates brain injury in rats following carbon monoxide poisoning via different mechanisms
Q34170943G-CSF administration is neuroprotective following transient cerebral ischemia even in the absence of a functional NOS-2 gene
Q38342285G-CSF as an adjunctive therapy with umbilical cord blood cell transplantation for traumatic brain injury
Q37570899G-CSF for mobilizing transplanted bone marrow stem cells in rat model of Parkinson's disease.
Q28477416G-CSF prevents the progression of structural disintegration of white matter tracts in amyotrophic lateral sclerosis: a pilot trial
Q35596594G-CSF protects human brain vascular endothelial cells injury induced by high glucose, free fatty acids and hypoxia through MAPK and Akt signaling
Q30493856G-CSF protects motoneurons against axotomy-induced apoptotic death in neonatal mice
Q34981973G-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic
Q36229391G-CSF rescues the memory impairment of animal models of Alzheimer's disease
Q40516010G-CSF, rt-PA and combination therapy after experimental thromboembolic stroke
Q39317670G-CSF-mobilized Bone Marrow Mesenchymal Stem Cells Replenish Neural Lineages in Alzheimer's Disease Mice via CXCR4/SDF-1 Chemotaxis
Q36227832G-CSF/SCF reduces inducible arrhythmias in the infarcted heart potentially via increased connexin43 expression and arteriogenesis
Q43599090GM-CSF protects rat photoreceptors from death by activating the SRC-dependent signalling and elevating anti-apoptotic factors and neurotrophins
Q41561595GRP75 Involves in Retinal Ganglion Cell Apoptosis After Rat Optic Nerve Crush
Q35613992Gender-Specific Mechanism of Synaptic Impairment and Its Prevention by GCSF in a Mouse Model of ALS.
Q90700313Genotypic and phenotypic characterization of West Nile virus NS5 methyltransferase mutants
Q24615554Ginsenoside rd in experimental stroke: superior neuroprotective efficacy with a wide therapeutic window
Q57284893Granulocyte Colony Stimulating Factor Enhances Reward Learning through Potentiation of Mesolimbic Dopamine System Function
Q47566621Granulocyte Colony-Stimulating Factor (G-CSF) for the Treatment of Spinal Cord Injury
Q55209440Granulocyte Colony-Stimulating Factor Alleviates Bacterial-Induced Neuronal Apoptotic Damage in the Neonatal Rat Brain through Epigenetic Histone Modification.
Q48180769Granulocyte Colony-Stimulating Factor and Its Potential Application for Skeletal Muscle Repair and Regeneration.
Q39981228Granulocyte colony stimulating factor alters the phenotype of neuroblastoma cells: implications for disease-free survival of high-risk patients
Q35137333Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis.
Q34985230Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice
Q53216544Granulocyte colony stimulating factor neuroprotective effects on spinal motoneurons after ventral root avulsion.
Q34694819Granulocyte colony stimulating factor reduces brain injury in a cardiopulmonary bypass-circulatory arrest model of ischemia in a newborn piglet
Q33563023Granulocyte colony stimulating factor therapy for stroke: A pairwise meta-analysis of randomized controlled trial
Q34300608Granulocyte colony-stimulating factor (G-CSF) positive effects on muscle fiber degeneration and gait recovery after nerve lesion in MDX mice.
Q34500255Granulocyte colony-stimulating factor (G-CSF) protects oligodendrocyte and promotes hindlimb functional recovery after spinal cord injury in rats
Q34630942Granulocyte colony-stimulating factor (G-CSF) treatment in combination with transplantation of bone marrow cells is not superior to G-CSF treatment alone after cortical stroke in spontaneously hypertensive rats
Q36740527Granulocyte colony-stimulating factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans
Q21136403Granulocyte colony-stimulating factor activating HIF-1alpha acts synergistically with erythropoietin to promote tissue plasticity
Q35591273Granulocyte colony-stimulating factor attenuates delayed tPA-induced hemorrhagic transformation in ischemic stroke rats by enhancing angiogenesis and vasculogenesis
Q44359967Granulocyte colony-stimulating factor does not promote neurogenesis after experimental intracerebral haemorrhage.
Q42920403Granulocyte colony-stimulating factor enhances cellular proliferation and motor function recovery on rats subjected to traumatic brain injury
Q45979710Granulocyte colony-stimulating factor increases sympathetic reinnervation and the arrhythmogenic response to programmed electrical stimulation after myocardial infarction in rats.
Q48687818Granulocyte colony-stimulating factor off-target effect on nerve outgrowth promotes prostate cancer development.
Q36723127Granulocyte colony-stimulating factor promotes behavioral recovery in a mouse model of traumatic brain injury.
Q48697355Granulocyte colony-stimulating factor protects the brain against experimental stroke via inhibition of apoptosis and inflammation
Q47724526Granulocyte colony-stimulating factor significantly decreases density of hippocampal caspase 3-positive nuclei, thus ameliorating apoptosis-mediated damage, in a model of ischaemic neonatal brain injury
Q33780538Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis.
Q53452061Granulocyte macrophage-colony stimulating factor shows anti-apoptotic activity in neural progenitor cells via JAK/STAT5-Bcl-2 pathway
Q37041123Granulocyte stimulating factor attenuates hypoxic-ischemic brain injury by inhibiting apoptosis in neonatal rats.
Q33772176Granulocyte-Colony Stimulating Factor (G-CSF) Accelerates Wound Healing in Hemorrhagic Shock Rats by Enhancing Angiogenesis and Attenuating Apoptosis.
Q36192434Granulocyte-Colony Stimulating Factor (G-CSF) for stroke: an individual patient data meta-analysis
Q53439244Granulocyte-Colony Stimulating Factor Increases Cerebral Blood Flow via a NO Surge Mediated by Akt/eNOS Pathway to Reduce Ischemic Injury.
Q28732850Granulocyte-colony stimulating factor (G-CSF) improves motor recovery in the rat impactor model for spinal cord injury
Q28744358Granulocyte-colony stimulating factor (G-CSF) in stroke patients with concomitant vascular disease--a randomized controlled trial
Q36093819Granulocyte-colony stimulating factor activates JAK2/PI3K/PDE3B pathway to inhibit corticosterone synthesis in a neonatal hypoxic-ischemic brain injury rat model.
Q48940108Granulocyte-colony stimulating factor alleviates perinatal hypoxia-induced decreases in hippocampal synaptic efficacy and neurogenesis in the neonatal rat brain
Q38481539Granulocyte-colony stimulating factor ameliorates irradiation-induced suppression of hippocampal neurogenesis in adult mice
Q57153034Granulocyte-colony stimulating factor and umbilical cord blood cell transplantation: Synergistic therapies for the treatment of traumatic brain injury
Q35213148Granulocyte-colony stimulating factor attenuates oligomeric amyloid β neurotoxicity by activation of neprilysin
Q47861165Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine
Q34330344Granulocyte-colony stimulating factor decreases the extent of ovarian damage caused by cisplatin in an experimental rat model
Q37689522Granulocyte-colony stimulating factor for stroke treatment: mechanisms of action and efficacy in preclinical studies
Q42854392Granulocyte-colony stimulating factor improves Parkinson's disease associated with co-morbid depression: an experimental exploratory study
Q24655277Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis
Q39562503Granulocyte-colony stimulating factor in combination with stem cell factor confers greater neuroprotection after hypoxic-ischemic brain damage in the neonatal rats than a solitary treatment.
Q35836825Granulocyte-colony stimulating factor inhibits apoptotic neuron loss after neonatal hypoxia-ischemia in rats
Q48873132Granulocyte-colony stimulating factor promotes brain repair following traumatic brain injury by recruitment of microglia and increasing neurotrophic factor expression
Q35088982Granulocyte-colony stimulating factor promotes liver repair and induces oval cell migration and proliferation in rats
Q51010634Granulocyte-colony stimulating factor protects memory impairment in the senescence-accelerated mouse (SAM)-P10.
Q46878329Granulocyte-colony stimulating factor: a new player for the enteric nervous system
Q49646739Granulocyte-colony-stimulating factor (G-CSF) signaling in spinal microglia drives visceral sensitization following colitis
Q94400913Granulocyte‐colony stimulating factor administration for subfertile women undergoing assisted reproduction
Q36608807Growth factors and stroke
Q54189658Growth factors and synaptic plasticity in relapsing-remitting multiple sclerosis.
Q35216143Growth factors in ischemic stroke.
Q60678255Hematopoietic colony–stimulating factors mediate tumor-nerve interactions and bone cancer pain
Q42024722Hematopoietic growth factors pass through the blood-brain barrier in intact rats
Q38816820Hematopoietic stem and progenitor cells as novel prognostic biomarkers of longevity in a murine model for amyotrophic lateral sclerosis
Q36824005Hematopoietic stem cells are pluripotent and not just "hematopoietic".
Q38190431Herbal medicines for ischemic stroke: combating inflammation as therapeutic targets
Q39306350Hippocampal neurogenesis and the brain repair response to brief stereotaxic insertion of a microneedle.
Q37592633Histological Architecture Underlying Brain-Immune Cell-Cell Interactions and the Cerebral Response to Systemic Inflammation
Q43216252Hypothalamic proline rich polypeptide regulates hematopoiesis
Q45874222Hypoxia-specific GM-CSF-overexpressing neural stem cells improve graft survival and functional recovery in spinal cord injury
Q40804722IL-6, IL-8, IP-10, MCP-1 and G-CSF are significantly increased in cerebrospinal fluid but not in sera of patients with central neuropsychiatric lupus erythematosus
Q34244910Immune system modulates the function of adult neural stem cells.
Q34158254Immunological control of adult neural stem cells
Q34451574Impact of constitutional polymorphisms in VCAM1 and CD44 on CD34+ cell collection yield after administration of granulocyte colony-stimulating factor to healthy donors.
Q40754685Impact of the neutrophil response to granulocyte colony-stimulating factor on the risk of hemorrhage when used in combination with tissue plasminogen activator during the acute phase of experimental stroke
Q37572370Implications of vascular endothelial growth factor for postischemic neurovascular remodeling.
Q37091669Improving outcome after stroke: overcoming the translational roadblock
Q47704356In Vitro Microfluidic Models for Neurodegenerative Disorders.
Q48327541In vivo administration of granulocyte colony-stimulating factor restores long-term depression in hippocampal slices prepared from transgenic APP/PS1 mice
Q45938256Increase of SCF plasma concentration during donepezil treatment of patients with early Alzheimer's disease.
Q48380634Increased recruitment of bone marrow-derived cells into the brain associated with altered brain cytokine profile in senescence-accelerated mice
Q38703435Induction of Neurorestoration From Endogenous Stem Cells
Q37474699Inflammatory Disequilibrium in Stroke
Q37997911Inflammatory regulators of redirected neural migration in the injured brain
Q33568772Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
Q35459565Intranasal Delivery of Granulocyte Colony-Stimulating Factor Enhances Its Neuroprotective Effects Against Ischemic Brain Injury in Rats
Q40245798Intrathecal upregulation of granulocyte colony stimulating factor and its neuroprotective actions on motor neurons in amyotrophic lateral sclerosis
Q35648103Investigational therapies for ischemic stroke: neuroprotection and neurorecovery
Q48600819Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke.
Q37686762Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury
Q42053383LIM domain only 4 protein promotes granulocyte colony-stimulating factor-induced signaling in neurons
Q35098308Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats
Q34011525Maintenance of the enteric stem cell niche by bacterial lipopolysaccharides? Evidence and perspectives
Q37421064Mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis
Q41827325Mesenchymal stem cells expressing brain-derived neurotrophic factor enhance endogenous neurogenesis in an ischemic stroke model
Q28082627Microglia are crucial regulators of neuro-immunity during central nervous system tuberculosis
Q26773064Microglia-Mediated Neuroinflammation and Neurotrophic Factor-Induced Protection in the MPTP Mouse Model of Parkinson's Disease-Lessons from Transgenic Mice
Q34009248Mobilisation of hematopoietic CD34+ precursor cells in patients with acute stroke is safe--results of an open-labeled non randomized phase I/II trial
Q37027281Molecular mechanisms of apoptosis in cerebral ischemia: multiple neuroprotective opportunities
Q34059585Monocyte chemoattractant protein-1-deficiency impairs the expression of IL-6, IL-1β and G-CSF after transient focal ischemia in mice
Q47303075Monocyte count at onset predicts poststroke outcomes during a 90-day follow-up.
Q40350912Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke.
Q42697596Mononuclear cells from the cord blood and granulocytecolony stimulating factor-mobilized peripheral blood: is there a potential for treatment of cerebral palsy?
Q36437332Motor neuron-immune interactions: the vicious circle of ALS.
Q37358654Multifunctional actions of approved and candidate stroke drugs
Q33789162Multimodal Approaches for Regenerative Stroke Therapies: Combination of Granulocyte Colony-Stimulating Factor with Bone Marrow Mesenchymal Stem Cells is Not Superior to G-CSF Alone.
Q34473745Multimodality monitoring, inflammation, and neuroregeneration in subarachnoid hemorrhage
Q37233361Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue
Q53059092Nephro-protective effect of granulocyte colony-stimulating factor in streptozotocin induced diabetic rats.
Q36275171Neural precursor cells are protected from apoptosis induced by trophic factor withdrawal or genotoxic stress by inhibitors of glycogen synthase kinase 3.
Q27001127Neural precursor cells in the ischemic brain - integration, cellular crosstalk, and consequences for stroke recovery
Q37085039Neural stem cells in the mammalian brain
Q38622588Neurogenesis following Stroke Affecting the Adult Brain
Q33370650Neuronal hypoxia in vitro: investigation of therapeutic principles of HUCB-MNC and CD133+ stem cells
Q36829280Neuroprotection against neurodegenerative diseases: development of a novel hybrid neuroprotective peptide Colivelin.
Q37991061Neuroprotection for ischaemic stroke: translation from the bench to the bedside
Q26853031Neuroprotection for stroke: current status and future perspectives
Q48077973Neuroprotective Effects of Direct Intrathecal Administration of Granulocyte Colony-Stimulating Factor in Rats with Spinal Cord Injury
Q47868304Neuroprotective Effects of Filgrastim in Rotenone-Induced Parkinson's Disease in Rats: Insights into its Anti-Inflammatory, Neurotrophic, and Antiapoptotic Effects
Q36680605Neuroprotective and Angiogenic Effects of Bone Marrow Transplantation Combined With Granulocyte Colony-Stimulating Factor in a Mouse Model of Amyotrophic Lateral Sclerosis
Q45719870Neuroprotective effects of granulocyte-colony stimulating factor in a novel transgenic mouse model of SCA17.
Q37028288Neurorestoration after stroke.
Q33985590Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand?
Q34240286Neutrophil contribution to spinal cord injury and repair
Q55191874Neutrophils in traumatic brain injury (TBI): friend or foe?
Q34461560New hope for stroke patients: mobilization of endogenous stem cells
Q36445653Noninvasive tracking of gene transcript and neuroprotection after gene therapy
Q35953384Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields
Q54962608Omics-Based Approach Reveals Complement-Mediated Inflammation in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS).
Q39639495Pegylated granulocyte colony-stimulating factor conveys long-term neuroprotection and improves functional outcome in a model of Parkinson's disease.
Q28486022Pharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malaria
Q43092577Post-MPTP treatment with granulocyte colony-stimulating factor improves nigrostriatal function in the mouse model of Parkinson's disease
Q36883767Potential roles of bone marrow stem cells in stroke therapy
Q36151822Preliminary study on electrophysiological changes after cellular autograft in age-related macular degeneration
Q50979109Prevention of an increase in cortical ligand binding to AMPA receptors may represent a novel mechanism of endogenous brain protection by G-CSF after ischemic stroke.
Q39191007Production of IL-8, IL-17, IFN-gamma and IP-10 in human astrocytes correlates with alphavirus attenuation
Q36216243Profiling and Identification of Novel Immunogenic Proteins of Staphylococcus hyicus ZC-4 by Immunoproteomic Assay
Q38107439Progress in stem cell therapy for major human neurological disorders.
Q47106198Promising neuroprotective strategies for traumatic spinal cord injury with a focus on the differential effects among anatomical levels of injury
Q38675024Promoting recovery from ischemic stroke
Q38476445Protection of spermatogenesis against gamma ray-induced damage by granulocyte colony-stimulating factor in mice
Q48787833Protective effect of granulocyte colony-stimulating factor on intracerebral hemorrhage in rat.
Q52603658Recent Advances: Decoding Alzheimer's Disease With Stem Cells.
Q48382225Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels
Q51697440Recombinant human granulocyte colony-stimulating factor reduces colonic epithelial cell apoptosis and ameliorates murine dextran sulfate sodium-induced colitis.
Q47779952Recombinant human granulocyte-colony stimulating factor administration for treating amyotrophic lateral sclerosis: A pilot study
Q56927463Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Q40355155Regulatory issues in aging pharmacology
Q42970221Repeated mesenchymal stem cell treatment after neonatal hypoxia-ischemia has distinct effects on formation and maturation of new neurons and oligodendrocytes leading to restoration of damage, corticospinal motor tract activity, and sensorimotor func
Q33862328Role of neural precursor cells in promoting repair following stroke
Q36830938Role of neuroinflammation in adult neurogenesis and Alzheimer disease: therapeutic approaches
Q37190629Role of signal transducer and activator of transcription 3 in neuronal survival and regeneration
Q36709806Role of the pituitary–adrenal axis in granulocyte-colony stimulating factor-induced neuroprotection against hypoxia–ischemia in neonatal rats
Q38446890Safety and efficacy of G-CSF mobilization and collection of autologous peripheral blood stem cells in children with cerebral palsy
Q38757929Secretome Cues Modulate the Neurogenic Potential of Bone Marrow and Dental Stem Cells
Q37817069Seeing old friends from a different angle: novel properties of hematopoietic growth factors in the healthy and diseased brain
Q55228910Serial Changes of Cytokines in Children with Cerebral Palsy Who Received Intravenous Granulocyte-colony Stimulating Factor Followed by Autologous Mobilized Peripheral Blood Mononuclear Cells.
Q41903809Serum granulocyte colony-stimulating factor and Alzheimer's disease
Q51832847Sesamol ameliorates radiation induced DNA damage in hematopoietic system of whole body γ-irradiated mice.
Q31152401Soluble prokaryotic overexpression and purification of bioactive human granulocyte colony-stimulating factor by maltose binding protein and protein disulfide isomerase
Q88998644Stem Cell Factor in Combination with Granulocyte Colony-Stimulating Factor reduces Cerebral Capillary Thrombosis in a Mouse Model of CADASIL
Q38903653Stem Cell-Based Therapies for Ischemic Stroke: Preclinical Results and the Potential of Imaging-Assisted Evaluation of Donor Cell Fate and Mechanisms of Brain Regeneration
Q34129832Stem cell therapy for cerebral ischemia: from basic science to clinical applications
Q33981407Stem cells and G-CSF for treating neuroinflammation in traumatic brain injury: aging as a comorbidity factor
Q37053159Stem cells and neurological diseases.
Q37453637Stem cells for enhancing recovery after stroke: a review.
Q33957236Stem cells for ischemic brain injury: a critical review
Q53825391Study protocol for the G-SPIRIT trial: a randomised, placebo-controlled, double-blinded phase III trial of granulocyte colony-stimulating factor-mediated neuroprotection for acute spinal cord injury.
Q28475375Synergetic effects of granulocyte-colony stimulating factor and cognitive training on spatial learning and survival of newborn hippocampal neurons
Q40961556System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice
Q93090713Systemic Factors Trigger Vasculature Cells to Drive Notch Signaling and Neurogenesis in Neural Stem Cells in the Adult Brain
Q41229573Targeting Adult Neurogenesis for Poststroke Therapy
Q26798071The Granulocyte-colony stimulating factor has a dual role in neuronal and vascular plasticity
Q54748291The arrythmogenic potential of post-myocardial infarction cytokine treatment.
Q36713511The combination of granulocyte colony-stimulating factor and stem cell factor significantly increases the number of bone marrow-derived endothelial cells in brains of mice following cerebral ischemia
Q46441301The effect of granulocyte colony-stimulating factor administration on carbon monoxide neurotoxicity in rats.
Q41959494The effect of granulocyte-colony stimulating factor in global cerebral ischemia in rats
Q27305224The effects of hematopoietic growth factors on neurite outgrowth
Q30463376The hematopoietic cytokine granulocyte-macrophage colony stimulating factor is important for cognitive functions
Q33303476The hematopoietic factor GM-CSF (granulocyte-macrophage colony-stimulating factor) promotes neuronal differentiation of adult neural stem cells in vitro
Q30460097The interleukin 3 gene (IL3) contributes to human brain volume variation by regulating proliferation and survival of neural progenitors
Q38275171The ongoing pursuit of neuroprotective therapies in Parkinson disease
Q30855096The potential of hematopoietic growth factors for treatment of Alzheimer's disease: a mini-review
Q21284135The receptor for granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system
Q36055381The role of granulocyte colony-stimulating factor in the neutrophilia observed in the fetal inflammatory response syndrome
Q43275672The role of granulocyte-colony stimulating factor (G-CSF) in the healthy brain: a characterization of G-CSF-deficient mice
Q37087845The role of stem cell factor and granulocyte-colony stimulating factor in treatment of stroke
Q55100841Toll-like receptor 2 promotes neurogenesis from the dentate gyrus after photothrombotic cerebral ischemia in mice.
Q36789097Transcriptional regulation of neurogenesis: potential mechanisms in cerebral ischemia
Q36522091Translating G-CSF as an Adjunct Therapy to Stem Cell Transplantation for Stroke
Q36523745Transplantation of Human Adipose Tissue-Derived Mesenchymal Stem Cells Restores the Neurobehavioral Disorders of Rats With Neonatal Hypoxic-Ischemic Encephalopathy
Q36274847Transplantation of adult neural progenitor cells transfected with vascular endothelial growth factor rescues grafted cells in the rat brain
Q47286190Turning Death to Growth: Hematopoietic Growth Factors Promote Neurite Outgrowth through MEK/ERK/p53 Pathway.
Q48583625Umbilical cord blood cell and granulocyte-colony stimulating factor: combination therapy for traumatic brain injury
Q37762259Use of growth factors for the treatment of Parkinson's disease
Q48293605Voluntary exercise enhances survival and migration of neural progenitor cells after intracerebral haemorrhage in mice
Q61803794Zinc Improves Functional Recovery by Regulating the Secretion of Granulocyte Colony Stimulating Factor From Microglia/Macrophages After Spinal Cord Injury
Q35602819pH responsive granulocyte colony-stimulating factor variants with implications for treating Alzheimer's disease and other central nervous system disorders

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