scholarly article | Q13442814 |
P50 | author | Jeremy Luban | Q50285713 |
P2093 | author name string | Elena Sokolskaja | |
Lionel Berthoux | |||
Sarah Sebastian | |||
P2860 | cites work | TRIM5alpha selectively binds a restriction-sensitive retroviral capsid | Q21245207 |
Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells | Q24290922 | ||
The tripartite motif family identifies cell compartments | Q24291183 | ||
TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells | Q37416225 | ||
A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrict HIV-1. | Q37513372 | ||
Lv1 inhibition of human immunodeficiency virus type 1 is counteracted by factors that stimulate synthesis or nuclear translocation of viral cDNA | Q37583411 | ||
Influence of gag on human immunodeficiency virus type 1 species-specific tropism | Q37583481 | ||
Selection for loss of Ref1 activity in human cells releases human immunodeficiency virus type 1 from cyclophilin A dependence during infection | Q37583499 | ||
Target cell cyclophilin A modulates human immunodeficiency virus type 1 infectivity | Q37596441 | ||
Specific incorporation of cyclophilin A into HIV-1 virions | Q38302257 | ||
As(2)O(3) enhances retroviral reverse transcription and counteracts Ref1 antiviral activity | Q38906287 | ||
Restriction of multiple divergent retroviruses by Lv1 and Ref1 | Q39056684 | ||
Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid | Q40556428 | ||
Stable gene transfer to the nervous system using a non-primate lentiviral vector | Q40910553 | ||
Catalysis of protein folding by prolyl isomerase | Q41430633 | ||
Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors | Q44536206 | ||
Activation of a phytopathogenic bacterial effector protein by a eukaryotic cyclophilin | Q45299707 | ||
Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance. | Q52549320 | ||
The cis/trans interconversion of the calcium regulating hormone calcitonin is catalyzed by cyclophilin | Q70733944 | ||
Structure of the amino-terminal core domain of the HIV-1 capsid protein | Q71142552 | ||
Molecular recognition in the HIV-1 capsid/cyclophilin A complex | Q73511357 | ||
Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues | Q24303941 | ||
BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta | Q24310515 | ||
Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin | Q24338951 | ||
Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes | Q24535752 | ||
Trim5alpha protein restricts both HIV-1 and murine leukemia virus | Q24561922 | ||
The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities | Q24561930 | ||
Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha | Q24561939 | ||
Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid | Q27734262 | ||
Cyclophilin A peptidyl-prolyl isomerase activity promotes ZPR1 nuclear export | Q27936211 | ||
Determination of enzymatic catalysis for the cis-trans-isomerization of peptide binding in proline-containing peptides | Q28267643 | ||
The human immunodeficiency virus type 1 capsid p2 domain confers sensitivity to the cyclophilin-binding drug SDZ NIM 811 | Q28378949 | ||
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys | Q29547689 | ||
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo | Q29616612 | ||
Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain | Q29618741 | ||
Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1 | Q29618920 | ||
Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B | Q29618922 | ||
Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells | Q30883515 | ||
Retrovirus restriction by TRIM5alpha variants from Old World and New World primates | Q33707501 | ||
Use of a transient assay for studying the genetic determinants of Fv1 restriction | Q33809632 | ||
Species-specific, postentry barriers to primate immunodeficiency virus infection | Q33824990 | ||
Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction | Q33834617 | ||
Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death | Q33876302 | ||
Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A | Q34024214 | ||
Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism | Q34154693 | ||
Restriction of lentivirus in monkeys | Q34154725 | ||
A dominant block to HIV-1 replication at reverse transcription in simian cells | Q34161825 | ||
Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4. | Q34176705 | ||
Functional association of cyclophilin A with HIV-1 virions | Q34326356 | ||
A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction | Q34384150 | ||
Human and simian immunodeficiency virus capsid proteins are major viral determinants of early, postentry replication blocks in simian cells | Q34462276 | ||
A conserved mechanism of retrovirus restriction in mammals | Q35422974 | ||
Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription | Q35861172 | ||
The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses | Q35866801 | ||
Transfer of the HIV-1 cyclophilin-binding site to simian immunodeficiency virus from Macaca mulatta can confer both cyclosporin sensitivity and cyclosporin dependence | Q36602545 | ||
P433 | issue | 41 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 14849-53 | |
P577 | publication date | 2005-10-11 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells | |
P478 | volume | 102 |
Q24289157 | 'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic era |
Q35105663 | A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection |
Q40176627 | A mutation in alpha helix 3 of CA renders human immunodeficiency virus type 1 cyclosporin A resistant and dependent: rescue by a second-site substitution in a distal region of CA. |
Q37780981 | A new functional role of HIV-1 integrase during uncoating of the viral core |
Q34565670 | A novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screen |
Q34288181 | Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α |
Q36315013 | Analysis of human cell heterokaryons demonstrates that target cell restriction of cyclosporine-resistant human immunodeficiency virus type 1 mutants is genetically dominant |
Q34353389 | Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner |
Q38927893 | Both TRIM5alpha and TRIMCyp have only weak antiviral activity in canine D17 cells |
Q36537806 | Breaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives |
Q40698862 | Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo |
Q38281936 | Cell context-dependent involvement of ATR in early stages of retroviral replication |
Q39822140 | Cellular restriction targeting viral capsids perturbs human immunodeficiency virus type 1 infection of nondividing cells |
Q39698881 | Contribution of Cyclophilin A to determination of simian immunodeficiency virus tropism: a progress update |
Q39746758 | Contribution of RING domain to retrovirus restriction by TRIM5alpha depends on combination of host and virus |
Q36993953 | Correlation of naturally occurring HIV-1 resistance to DEB025 with capsid amino acid polymorphisms |
Q90429668 | Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core |
Q34434872 | Cyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cells |
Q38841693 | Cyclophilin A interacts with diverse lentiviral capsids |
Q41852306 | Cyclophilin A levels dictate infection efficiency of human immunodeficiency virus type 1 capsid escape mutants A92E and G94D. |
Q38695881 | Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid. |
Q90859869 | Cyclophilin A protects HIV-1 from restriction by human TRIM5α |
Q40287254 | Cyclophilin A renders human immunodeficiency virus type 1 sensitive to Old World monkey but not human TRIM5 alpha antiviral activity. |
Q27332017 | Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site |
Q35635089 | Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection |
Q41358229 | Cyclophilin A-dependent restriction of human immunodeficiency virus type 1 capsid mutants for infection of nondividing cells |
Q40286791 | Cyclophilin A: an auxiliary but not necessary cofactor for TRIM5alpha restriction of HIV-1. |
Q42140198 | Cyclophilin and viruses: cyclophilin as a cofactor for viral infection and possible anti-viral target. |
Q38121470 | Cyclophilins as modulators of viral replication |
Q35023710 | Cyclosporine increases human immunodeficiency virus type 1 vector transduction of primary mouse cells. |
Q38288599 | Determinants of cyclophilin A-dependent TRIM5 alpha restriction against HIV-1 |
Q36332027 | Dynamic allostery governs cyclophilin A-HIV capsid interplay |
Q40081157 | Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic |
Q48158877 | Editing of the human TRIM5 gene to introduce mutations with the potential to inhibit HIV-1. |
Q40171193 | Efficient transduction of simian cells by HIV-1-based lentiviral vectors that contain mutations in the capsid protein |
Q37835939 | Emerging picture of host chaperone and cyclophilin roles in RNA virus replication. |
Q45407731 | Evolution of feline immunodeficiency virus Gag proteins |
Q64078156 | Functional analysis of the secondary HIV-1 capsid binding site in the host protein cyclophilin A |
Q33602830 | Functional evidence for the involvement of microtubules and dynein motor complexes in TRIM5α-mediated restriction of retroviruses |
Q40112065 | Fusion of cyclophilin A to Fv1 enables cyclosporine-sensitive restriction of human and feline immunodeficiency viruses. |
Q38698793 | Gene Knockout Shows That PML (TRIM19) Does Not Restrict the Early Stages of HIV-1 Infection in Human Cell Lines |
Q28541423 | Gene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent manner |
Q35108494 | Generation of HIV-1 derivatives that productively infect macaque monkey lymphoid cells |
Q39329959 | Generation of a monkey-tropic human immunodeficiency virus type 1 carrying env from a CCR5-tropic subtype C clinical isolate |
Q33548284 | Generation of human TRIM5alpha mutants with high HIV-1 restriction activity |
Q21283880 | Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties |
Q37244940 | Genotyping of TRIM5 locus in northern pig-tailed macaques (Macaca leonina), a primate species susceptible to Human Immunodeficiency Virus type 1 infection. |
Q35902681 | HIV Restriction Factors and Mechanisms of Evasion |
Q24614498 | HIV type 1 Gag as a target for antiviral therapy |
Q34624282 | Homology-based identification of capsid determinants that protect HIV1 from human TRIM5α restriction |
Q35850448 | Host cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication |
Q33775595 | Host genetics influences on HIV type-1 disease |
Q34600020 | How TRIM5alpha defends against retroviral invasions |
Q37382519 | Human cellular restriction factors that target HIV-1 replication |
Q37582948 | Human immunodeficiency virus, restriction factors, and interferon |
Q36315023 | Identification of an arsenic-sensitive block to primate lentiviral infection of human dendritic cells |
Q24656091 | Independent evolution of an antiviral TRIMCyp in rhesus macaques |
Q34319249 | Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogens |
Q39616618 | Isolation of an active Lv1 gene from cattle indicates that tripartite motif protein-mediated innate immunity to retroviral infection is widespread among mammals |
Q28546614 | Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration |
Q37121420 | Modulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell type |
Q34149568 | Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction |
Q39207567 | Murine double minute 2 as a modulator of retroviral restrictions mediated by TRIM5alpha |
Q28474342 | Polymorphisms in the regulatory region of the Cyclophilin A gene influence the susceptibility for HIV-1 infection |
Q39601777 | Porcine endogenous retroviruses PERV A and A/C recombinant are insensitive to a range of divergent mammalian TRIM5alpha proteins including human TRIM5alpha |
Q38751544 | Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells |
Q36242630 | Preclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 Transgene |
Q38997444 | Productive replication and evolution of HIV-1 in ferret cells. |
Q35101356 | Proteasome inhibition reveals that a functional preintegration complex intermediate can be generated during restriction by diverse TRIM5 proteins |
Q37950254 | Protein intrinsic disorder as a flexible armor and a weapon of HIV-1. |
Q36766589 | Reconstitution of the myeloid and lymphoid compartments after the transplantation of autologous and genetically modified CD34+ bone marrow cells, following gamma irradiation in cynomolgus macaques |
Q33288731 | Regulatory polymorphisms in the cyclophilin A gene, PPIA, accelerate progression to AIDS. |
Q24630459 | Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha |
Q35140364 | Role of TRIM5α RING domain E3 ubiquitin ligase activity in capsid disassembly, reverse transcription blockade, and restriction of simian immunodeficiency virus |
Q39641782 | Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization |
Q24547409 | Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor |
Q41824328 | Strain-specific differences in the impact of human TRIM5alpha, different TRIM5alpha alleles, and the inhibition of capsid-cyclophilin A interactions on the infectivity of HIV-1. |
Q24300173 | TRIM5 is an innate immune sensor for the retrovirus capsid lattice |
Q39998437 | TRIM5alpha-independent anti-human immunodeficiency virus type 1 activity mediated by cyclophilin A in Old World monkey cells |
Q37410802 | Target cell type-dependent modulation of human immunodeficiency virus type 1 capsid disassembly by cyclophilin A. |
Q34162254 | The TPR domain in the host Cyp40-like cyclophilin binds to the viral replication protein and inhibits the assembly of the tombusviral replicase |
Q39187298 | The V86M mutation in HIV-1 capsid confers resistance to TRIM5α by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import |
Q36848296 | The control of viral infection by tripartite motif proteins and cyclophilin A. |
Q39253660 | The host proteins transportin SR2/TNPO3 and cyclophilin A exert opposing effects on HIV-1 uncoating. |
Q38430710 | The innate immune roles of host factors TRIM5α and Cyclophilin A on HIV-1 replication |
Q36714770 | The interferon-induced antiviral protein PML (TRIM19) promotes the restriction and transcriptional silencing of lentiviruses in a context-specific, isoform-specific fashion |
Q34058124 | The mouse IAPE endogenous retrovirus can infect cells through any of the five GPI-anchored Ephrin A proteins |
Q38274889 | The role of immunophilins in viral infection |
Q27313409 | Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells |
Q38088406 | Using TRIM5α as an HIV therapeutic: the alpha gene? |
Q33630030 | Variants in host viral replication cycle genes are associated with heterosexual HIV-1 acquisition in Africans |
Q35947645 | Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells |
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