| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Arnoud Sonnenberg | |
| Kevin Wilhelmsen | |||
| Sandy H M Litjens | |||
| P2860 | cites work | The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expression | Q24291264 |
| Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells | Q24302158 | ||
| Plectin deficiency results in muscular dystrophy with epidermolysis bullosa | Q24310411 | ||
| Shc phosphotyrosine-binding domain dominantly interacts with epidermal growth factor receptors and mediates Ras activation in intact cells | Q24324437 | ||
| Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly | Q24336701 | ||
| Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines | Q24338981 | ||
| The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation | Q24532185 | ||
| Cloning and sequence analysis of beta-4 cDNA: an integrin subunit that contains a unique 118 kd cytoplasmic domain | Q24556558 | ||
| Defective expression of plectin/HD1 in epidermolysis bullosa simplex with muscular dystrophy | Q24562137 | ||
| A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors | Q24567522 | ||
| Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes | Q24598414 | ||
| Calx, a Na-Ca exchanger gene of Drosophila melanogaster | Q24657862 | ||
| Expression of tumor antigen correlated with metastatic potential of Lewis lung carcinoma and B16 melanoma clones in mice | Q69614879 | ||
| Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures | Q70054660 | ||
| Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion | Q74037504 | ||
| The interaction of plectin with actin: evidence for cross-linking of actin filaments by dimerization of the actin-binding domain of plectin | Q74331004 | ||
| The alpha3 laminin subunit, alpha6beta4 and alpha3beta1 integrin coordinately regulate wound healing in cultured epithelial cells and in the skin | Q78021811 | ||
| The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes | Q24670149 | ||
| Binding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding | Q24670751 | ||
| Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180 | Q24682604 | ||
| Integrin beta 4 mutations associated with junctional epidermolysis bullosa with pyloric atresia | Q28118736 | ||
| Epidermolysis bullosa with congenital pyloric atresia: novel mutations in the beta 4 integrin gene (ITGB4) and genotype/phenotype correlations | Q28186379 | ||
| The emerging role of lysophosphatidic acid in cancer | Q28191543 | ||
| The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration | Q28201887 | ||
| Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture | Q28255914 | ||
| Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization | Q28283989 | ||
| Interaction of BP180 (type XVII collagen) and alpha6 integrin is necessary for stabilization of hemidesmosome structure | Q28291681 | ||
| Homozygous deletion mutations in the plectin gene (PLEC1) in patients with epidermolysis bullosa simplex associated with late-onset muscular dystrophy | Q28294894 | ||
| Identification and characterization of a novel antigen complex on mouse mammary tumor cells using a monoclonal antibody against platelet glycoprotein Ic | Q28339255 | ||
| Characterization of mice lacking the tetraspanin superfamily member CD151 | Q28587010 | ||
| Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival | Q28592841 | ||
| Gene targeting of BPAG1: abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration | Q28593672 | ||
| Dynamics of the alpha6beta4 integrin in keratinocytes | Q30476613 | ||
| Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes | Q31485514 | ||
| Unique expression pattern of the alpha6beta4 integrin and laminin-5 in human prostate carcinoma | Q33667939 | ||
| Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes | Q33899956 | ||
| Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells | Q33953411 | ||
| Mitochondrial division: New partners in membrane pinching | Q34169680 | ||
| Towards a mechanistic understanding of tumor invasion--lessons from the alpha6beta 4 integrin | Q34231953 | ||
| Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell adhesion and migration | Q34274897 | ||
| Identification and characterization of human LLGL4 gene and mouse Llgl4 gene in silico | Q34295332 | ||
| Novel ITGB4 mutations in lethal and nonlethal variants of epidermolysis bullosa with pyloric atresia: missense versus nonsense | Q34387737 | ||
| Platelet glycoproteins Ia, Ic, and IIa are physicochemically indistinguishable from the very late activation antigens adhesion-related proteins of lymphocytes and other cell types | Q35809833 | ||
| Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB. | Q35913517 | ||
| Molecular genetic studies of a human epidermal autoantigen (the 180-kD bullous pemphigoid antigen/BP180): identification of functionally important sequences within the BP180 molecule and evidence for an interaction between BP180 and alpha 6 integrin | Q36235763 | ||
| EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion | Q36294119 | ||
| p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB | Q36316304 | ||
| Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells | Q36316642 | ||
| Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis | Q36322294 | ||
| Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells | Q36323634 | ||
| Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors | Q36324930 | ||
| Compartmentalization of integrin α6β4 signaling in lipid rafts | Q36325504 | ||
| Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion | Q36529725 | ||
| beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium | Q37460431 | ||
| Protein kinase C-alpha phosphorylation of specific serines in the connecting segment of the beta 4 integrin regulates the dynamics of type II hemidesmosomes | Q37732243 | ||
| Integrin alpha6beta4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells | Q38326221 | ||
| Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion | Q39460470 | ||
| Specificity of binding of the plectin actin-binding domain to beta4 integrin | Q39938221 | ||
| Integrin alpha 6 beta 4 forms a complex with the cytoskeletal protein HD1 and induces its redistribution in transfected COS-7 cells | Q40243433 | ||
| The alpha6beta4 integrin maintains the survival of human breast carcinoma cells in vivo | Q40345022 | ||
| Beta4 integrin is a transforming molecule that unleashes Met tyrosine kinase tumorigenesis | Q40345158 | ||
| NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK. | Q40431585 | ||
| Keratinocytes display normal proliferation, survival and differentiation in conditional beta4-integrin knockout mice. | Q40454581 | ||
| Integrin alpha3beta1 directs the stabilization of a polarized lamellipodium in epithelial cells through activation of Rac1. | Q40533058 | ||
| The Met receptor and alpha 6 beta 4 integrin can function independently to promote carcinoma invasion | Q40552093 | ||
| A function for the integrin alpha 6 beta 4 in the hemidesmosome | Q40642598 | ||
| Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes. | Q40648507 | ||
| A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth | Q40765252 | ||
| Ligand-independent role of the beta 4 integrin subunit in the formation of hemidesmosomes. | Q41040267 | ||
| Linking integrin alpha6beta4-based cell adhesion to the intermediate filament cytoskeleton: direct interaction between the beta4 subunit and plectin at multiple molecular sites. | Q41043907 | ||
| Activation of the p21 pathway of growth arrest and apoptosis by the beta 4 integrin cytoplasmic domain | Q41293280 | ||
| The alpha 6 beta 4 integrin is a receptor for both laminin and kalinin | Q41476163 | ||
| Expression of alpha 6 beta 4 integrin increases during malignant conversion of mouse epidermal keratinocytes: association of beta 4 subunit to the cytokeratin fraction | Q41611433 | ||
| Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement membranes | Q41683771 | ||
| Nuclear factor kappaB subunits induce epithelial cell growth arrest | Q41756058 | ||
| Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain. | Q41762995 | ||
| The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration | Q41892013 | ||
| The intracellular functions of alpha6beta4 integrin are regulated by EGF. | Q41948258 | ||
| Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments | Q41964164 | ||
| Expression of NF-kappaB in epidermis and the relationship between NF-kappaB activation and inhibition of keratinocyte growth | Q42441349 | ||
| Alpha 6 beta 4 integrin regulates keratinocyte chemotaxis through differential GTPase activation and antagonism of alpha 3 beta 1 integrin | Q42444714 | ||
| p38 MAPK is a critical regulator of the constitutive and the beta4 integrin-regulated expression of IL-6 in human normal thymic epithelial cells. | Q42451854 | ||
| Molecular consequences of deletion of the cytoplasmic domain of bullous pemphigoid 180 in a patient with predominant features of epidermolysis bullosa simplex | Q42457168 | ||
| Thymocyte contact or monoclonal antibody-mediated clustering of 3beta1 or 6beta4 integrins activate interleukin-6 (IL-6) transcription factors (NF-kappaB and NF-IL6) and IL-6 production in human thymic epithelial cells | Q42463711 | ||
| Altered antigen expression predicts outcome in squamous cell carcinoma of the head and neck | Q42478303 | ||
| Zebrafish penner/lethal giant larvae 2 functions in hemidesmosome formation, maintenance of cellular morphology and growth regulation in the developing basal epidermis | Q42480541 | ||
| Targeted deletion of the integrin beta4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-kappaB, causing defects in epidermal growth and migration | Q42480617 | ||
| Pemphigoid nodularis associated with autoantibodies to the NC16A domain of BP180 and a hyperproliferative integrin profile | Q42511618 | ||
| Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice | Q42519143 | ||
| Deficiency of the integrin beta 4 subunit in junctional epidermolysis bullosa with pyloric atresia: consequences for hemidesmosome formation and adhesion properties. | Q42524072 | ||
| Deletion of a cytoplasmic domain of integrin beta4 causes epidermolysis bullosa simplex | Q42528721 | ||
| Cooperative signaling between alpha(6)beta(4) integrin and ErbB-2 receptor is required to promote phosphatidylinositol 3-kinase-dependent invasion | Q42803797 | ||
| Two different mutations in the cytoplasmic domain of the integrin beta 4 subunit in nonlethal forms of epidermolysis bullosa prevent interaction of beta 4 with plectin. | Q43910774 | ||
| A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody | Q44408810 | ||
| Laminin 5 deposition regulates keratinocyte polarization and persistent migration | Q44783999 | ||
| NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. | Q45982548 | ||
| CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin | Q50335739 | ||
| alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development. | Q52166185 | ||
| Integrin β4 signaling promotes tumor angiogenesis | Q57359862 | ||
| Ligation of integrin alpha 3beta 1 by laminin 5 at the wound edge activates Rho-dependent adhesion of leading keratinocytes on collagen | Q57446972 | ||
| The A9 antigen associated with aggressive human squamous carcinoma is structurally and functionally similar to the newly defined integrin alpha 6 beta 4 | Q67779727 | ||
| Analysis of the tumor-associated antigen TSP-180. Identity with alpha 6-beta 4 in the integrin superfamily | Q69095063 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| P304 | page(s) | 2877-2886 | |
| P577 | publication date | 2006-04-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis | |
| P478 | volume | 26 |
| Q38747491 | A basal cell defect promotes budding of prostatic intraepithelial neoplasia. |
| Q64259700 | A novel miR-365-3p/EHF/keratin 16 axis promotes oral squamous cell carcinoma metastasis, cancer stemness and drug resistance via enhancing β5-integrin/c-met signaling pathway |
| Q24337712 | ARRDC3 suppresses breast cancer progression by negatively regulating integrin beta4 |
| Q37629186 | Aberrant expression of laminin-332 promotes cell proliferation and cyst growth in ARPKD. |
| Q34611608 | Advances and perspectives of the architecture of hemidesmosomes: lessons from structural biology |
| Q37102288 | An activating beta1 integrin mutation increases the conversion of benign to malignant skin tumors. |
| Q34016825 | Basement membranes in skin: unique matrix structures with diverse functions? |
| Q39750624 | Beta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth |
| Q37858332 | Cell-extracellular matrix interactions in normal and diseased skin |
| Q39338632 | Combination of X-ray crystallography, SAXS and DEER to obtain the structure of the FnIII-3,4 domains of integrin α6β4. |
| Q79755946 | Conditional deletion of the Itgb4 integrin gene in Schwann cells leads to delayed peripheral nerve regeneration |
| Q39132510 | Crosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1. |
| Q34430926 | Cytoplasmic domain interactions of syndecan-1 and syndecan-4 with α6β4 integrin mediate human epidermal growth factor receptor (HER1 and HER2)-dependent motility and survival |
| Q35095341 | Down-regulation of Gli transcription factor leads to the inhibition of migration and invasion of ovarian cancer cells via integrin β4-mediated FAK signaling |
| Q36095805 | Dual Role of alpha6beta4 integrin in epidermal tumor growth: tumor-suppressive versus tumor-promoting function |
| Q39159186 | Dual roles of hemidesmosomal proteins in the pancreatic epithelium: the phosphoinositide 3-kinase decides. |
| Q39651560 | EGF-induced MAPK signaling inhibits hemidesmosome formation through phosphorylation of the integrin {beta}4. |
| Q99612745 | F-actin Regulates Osteoblastic Differentiation of Mesenchymal Stem Cells on TiO2 Nanotubes Through MKL1 and YAP/TAZ |
| Q36117925 | Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics |
| Q39922248 | Functional characterization of integrin alpha6beta4 adhesion interactions using soluble integrin constructs reveals the involvement of different functional domains in the beta4 subunit |
| Q38348785 | Human papillomavirus type 8 E2 protein unravels JunB/Fra-1 as an activator of the beta4-integrin gene in human keratinocytes. |
| Q39834616 | Hydrogen sulfide impairs keratinocyte cell growth and adhesion inhibiting mitogen-activated protein kinase signaling |
| Q35693163 | Integrated network analysis and logistic regression modeling identify stage-specific genes in Oral Squamous Cell Carcinoma |
| Q42826052 | Integrin signaling, cell survival, and anoikis: distinctions, differences, and differentiation |
| Q37625534 | Integrin α3β1 can function to promote spontaneous metastasis and lung colonization of invasive breast carcinoma. |
| Q30422511 | Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation |
| Q35572462 | Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice |
| Q42733634 | Integrin α6β4 in colorectal cancer |
| Q42149932 | Integrin β4 in EMT: an implication of renal diseases. |
| Q28473996 | Integrin-blocking antibodies delay keratinocyte re-epithelialization in a human three-dimensional wound healing model |
| Q50289826 | Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221) |
| Q44666075 | Interaction of Necl-4/CADM4 with ErbB3 and integrin α6 β4 and inhibition of ErbB2/ErbB3 signaling and hemidesmosome disassembly |
| Q24336974 | Interaction of nectin-like molecule 2 with integrin alpha6beta4 and inhibition of disassembly of integrin alpha6beta4 from hemidesmosomes |
| Q33809991 | Interaction of syndecan and alpha6beta4 integrin cytoplasmic domains: regulation of ErbB2-mediated integrin activation |
| Q40091012 | Intrinsic signaling functions of the beta4 integrin intracellular domain |
| Q35749387 | Involvement of alpha6beta4 integrin in the mechanisms that regulate breast cancer progression |
| Q33610587 | Laminin-binding integrins and their tetraspanin partners as potential antimetastatic targets |
| Q47616484 | Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB. |
| Q38285370 | Molecular architecture and function of the hemidesmosome |
| Q38504833 | Molecular architecture and function of the hemidesmosome |
| Q39083230 | Nectin and junctional adhesion molecule are critical cell adhesion molecules for the apico-basal alignment of adherens and tight junctions in epithelial cells. |
| Q37082480 | Outside-in signaling through integrins and cadherins: a central mechanism to control epidermal growth and differentiation? |
| Q37930504 | Overview: studying integrins in vivo |
| Q36586118 | Penfluridol: An Antipsychotic Agent Suppresses Metastatic Tumor Growth in Triple-Negative Breast Cancer by Inhibiting Integrin Signaling Axis |
| Q30547051 | RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells |
| Q37248197 | Regulation of beta 4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition |
| Q39415199 | Roles of Integrin α6β4 Glycosylation in Cancer |
| Q24647707 | Scratching the surface of skin development |
| Q41981638 | Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption |
| Q42124126 | Skin basement membrane: the foundation of epidermal integrity--BM functions and diverse roles of bridging molecules nidogen and perlecan |
| Q52718317 | Solo, a RhoA-targeting guanine nucleotide exchange factor, is critical for hemidesmosome formation and acinar development in epithelial cells. |
| Q24314867 | Structural basis of the interaction between integrin alpha6beta4 and plectin at the hemidesmosomes |
| Q35056474 | Suppression of anoikis in human intestinal epithelial cells: differentiation state-selective roles of α2β1, α3β1, α5β1, and α6β4 integrins |
| Q36283542 | Syndecan-1 and Syndecan-4 Capture Epidermal Growth Factor Receptor Family Members and the α3β1 Integrin Via Binding Sites in Their Ectodomains: NOVEL SYNSTATINS PREVENT KINASE CAPTURE AND INHIBIT α6β4-INTEGRIN-DEPENDENT EPITHELIAL CELL MOTILITY. |
| Q33575975 | The coordination between actin filaments and adhesion in mesenchymal migration |
| Q40020562 | The effect of butyric acid on adhesion molecule expression by human gingival epithelial cells |
| Q39144970 | The metastasis-associated molecule C4.4A promotes tissue invasion and anchorage independence by associating with the alpha6beta4 integrin |
| Q36303591 | Use of an in vivo animal model for assessing the role of integrin α(6)β(4) and syndecan-1 in early steps in papillomavirus infection |
| Q34912582 | Why integrin as a primary target for imaging and therapy |
| Q46209823 | miR-214 and hypoxia down-regulate Necl-2/CADM1 and enhance ErbB2/ErbB3 signaling |
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