scholarly article | Q13442814 |
P50 | author | Jenny Anderson | Q55299780 |
P2093 | author name string | Edward M Campbell | |
Thomas J Hope | |||
Ajith M Joseph | |||
Xiaolu Wu | |||
P2860 | cites work | The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha. | Q50768103 |
Restriction of HIV-1 (subtype B) replication at the entry step in rhesus macaque cells | Q71096662 | ||
HIV-1 genome nuclear import is mediated by a central DNA flap | Q73726795 | ||
The tripartite motif family identifies cell compartments | Q24291183 | ||
BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta | Q24310515 | ||
TRIM family proteins: retroviral restriction and antiviral defence | Q24329175 | ||
The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities | Q24561930 | ||
Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha | Q24561939 | ||
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys | Q29547689 | ||
Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain | Q29618741 | ||
Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1 | Q29618920 | ||
Proteasome inhibitors: valuable new tools for cell biologists | Q29620573 | ||
Species-specific, postentry barriers to primate immunodeficiency virus infection | Q33824990 | ||
Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction | Q33834617 | ||
Human tripartite motif 5alpha domains responsible for retrovirus restriction activity and specificity | Q33883891 | ||
Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism | Q34154693 | ||
Restriction of lentivirus in monkeys | Q34154725 | ||
A dominant block to HIV-1 replication at reverse transcription in simian cells | Q34161825 | ||
Intrinsic immunity: a front-line defense against viral attack | Q34360874 | ||
A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction | Q34384150 | ||
Human and simian immunodeficiency virus capsid proteins are major viral determinants of early, postentry replication blocks in simian cells | Q34462276 | ||
Abrogation of Ref1 retrovirus restriction in human cells | Q34970653 | ||
A conserved mechanism of retrovirus restriction in mammals | Q35422974 | ||
The high leukemogenic potential of Gross passage A murine leukemia virus maps in the region of the genome corresponding to the long terminal repeat and to the 3' end of env | Q36906709 | ||
Ubiquitin is part of the retrovirus budding machinery | Q37281238 | ||
Binding and susceptibility to postentry restriction factors in monkey cells are specified by distinct regions of the human immunodeficiency virus type 1 capsid | Q37730078 | ||
Characterization of murine leukemia virus restriction in mammals. | Q38906586 | ||
Loss of Fv-1 restriction in Balb/3T3 cells following infection with a single N tropic murine leukemia virus particle | Q38980087 | ||
Restriction of multiple divergent retroviruses by Lv1 and Ref1 | Q39056684 | ||
Single amino acid changes in the murine leukemia virus capsid protein gene define the target of Fv1 resistance | Q39147154 | ||
Antiviral activity of the proteasome on incoming human immunodeficiency virus type 1. | Q39578343 | ||
Human immunodeficiency virus cDNA metabolism: notable stability of two-long terminal repeat circles | Q39683262 | ||
A major genetic locus affecting resistance to infection with murine leukemia viruses. IV. Dose-response relationships in Fv-1-sensitive and resistant cell cultures | Q39930468 | ||
Fv-1 restriction and its effects on murine leukemia virus integration in vivo and in vitro | Q40067568 | ||
Differential restriction of human immunodeficiency virus type 2 and simian immunodeficiency virus SIVmac by TRIM5alpha alleles | Q40378098 | ||
Disruption of the actin cytoskeleton can complement the ability of Nef to enhance human immunodeficiency virus type 1 infectivity | Q40556468 | ||
Restriction of human immunodeficiency virus type 1 by TRIM-CypA occurs with rapid kinetics and independently of cytoplasmic bodies, ubiquitin, and proteasome activity | Q40669802 | ||
A quantitative assay for HIV DNA integration in vivo | Q40809319 | ||
Early replication block of human immunodeficiency virus type 1 in monkey cells | Q45788277 | ||
P433 | issue | 19 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | HIV | Q15787 |
P304 | page(s) | 7465-70 | |
P577 | publication date | 2006-05-09 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Proteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infection | |
P478 | volume | 103 |
Q34063469 | A TRIM5alpha exon 2 polymorphism is associated with protection from HIV-1 infection in the Pumwani sex worker cohort |
Q36827149 | A comparison of murine leukemia viruses that escape from human and rhesus macaque TRIM5αs |
Q37002260 | A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus |
Q37780981 | A new functional role of HIV-1 integrase during uncoating of the viral core |
Q34565670 | A novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screen |
Q33987871 | A single amino acid of human immunodeficiency virus type 2 capsid protein affects conformation of two external loops and viral sensitivity to TRIM5α. |
Q40081059 | APOBEC3G inhibits DNA strand transfer during HIV-1 reverse transcription. |
Q35641022 | African green monkey TRIM5α restriction in simian immunodeficiency virus-specific rhesus macaque effector CD4 T cells enhances their survival and antiviral function |
Q35825796 | An Anti-Influenza Virus Antibody Inhibits Viral Infection by Reducing Nucleus Entry of Influenza Nucleoprotein |
Q37336835 | An HIV-1 capsid binding protein TRIM11 accelerates viral uncoating |
Q42111956 | An active TRIM5 protein in rabbits indicates a common antiviral ancestor for mammalian TRIM5 proteins. |
Q37216261 | An expanded clade of rodent Trim5 genes |
Q38595370 | Anti-HIV-1 activity of Trim 37. |
Q35686784 | Antiretroviral restriction factors |
Q47146547 | Are Evolution and the Intracellular Innate Immune System Key Determinants in HIV Transmission? |
Q40422102 | Are we done monkeying around with TRIM5α? |
Q38222489 | Bacteriophages as vehicles for gene delivery into mammalian cells: prospects and problems |
Q36974763 | Biochemical characterization of a recombinant TRIM5alpha protein that restricts human immunodeficiency virus type 1 replication. |
Q38927893 | Both TRIM5alpha and TRIMCyp have only weak antiviral activity in canine D17 cells |
Q36537806 | Breaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives |
Q38618179 | Caging the beast: TRIM5α binding to the HIV-1 core |
Q24604018 | Cell-to-cell transmission of retroviruses: Innate immunity and interferon-induced restriction factors |
Q37954259 | Cellular restriction factors of feline immunodeficiency virus |
Q36484018 | Cellular restriction of retrovirus particle-mediated mRNA transfer |
Q39822140 | Cellular restriction targeting viral capsids perturbs human immunodeficiency virus type 1 infection of nondividing cells |
Q36491077 | Chance favors a prepared genome |
Q43805429 | Characterization of feline TRIM genes: molecular cloning, expression in tissues, and response to type I interferon |
Q34120302 | Characterization of the alpha interferon-induced postentry block to HIV-1 infection in primary human macrophages and T cells |
Q36298175 | Comparative requirements for the restriction of retrovirus infection by TRIM5alpha and TRIMCyp |
Q40024144 | Comparison of anti-viral activity of rhesus monkey and cynomolgus monkey TRIM5alphas against human immunodeficiency virus type 2 infection |
Q38903364 | Complementary Assays Reveal a Low Level of CA Associated with Viral Complexes in the Nuclei of HIV-1-Infected Cells |
Q35049239 | Complementary assays reveal a relationship between HIV-1 uncoating and reverse transcription |
Q27664241 | Conformational Adaptation of Asian Macaque TRIMCyp Directs Lineage Specific Antiviral Activity |
Q35192942 | Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha |
Q39746758 | Contribution of RING domain to retrovirus restriction by TRIM5alpha depends on combination of host and virus |
Q26864993 | Coupling viruses to dynein and kinesin-1 |
Q38841693 | Cyclophilin A interacts with diverse lentiviral capsids |
Q38695881 | Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid. |
Q90859869 | Cyclophilin A protects HIV-1 from restriction by human TRIM5α |
Q35635089 | Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection |
Q64077535 | Defects in assembly explain reduced antiviral activity of the G249D polymorphism in human TRIM5α |
Q34548171 | Delaying reverse transcription does not increase sensitivity of HIV-1 to human TRIM5α. |
Q38288599 | Determinants of cyclophilin A-dependent TRIM5 alpha restriction against HIV-1 |
Q35150045 | Determinants of the higher order association of the restriction factor TRIM5alpha and other tripartite motif (TRIM) proteins |
Q34073213 | Direct visualization of HIV-1 with correlative live-cell microscopy and cryo-electron tomography. |
Q40091689 | Early cytoplasmic uncoating is associated with infectivity of HIV-1. |
Q37028427 | Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay |
Q26852372 | Evolution of foamy viruses: the most ancient of all retroviruses |
Q28748328 | Evolution of the antiretroviral restriction factor TRIMCyp in Old World primates |
Q28487732 | Fates of retroviral core components during unrestricted and TRIM5-restricted infection |
Q36479939 | Feline immunodeficiency virus OrfA alters gene expression of splicing factors and proteasome-ubiquitination proteins |
Q33602830 | Functional evidence for the involvement of microtubules and dynein motor complexes in TRIM5α-mediated restriction of retroviruses |
Q36151323 | Functional genomics analyses of differential macaque peripheral blood mononuclear cell infections by human immunodeficiency virus-1 and simian immunodeficiency virus |
Q36088778 | Functional interplay between the B-box 2 and the B30.2(SPRY) domains of TRIM5alpha |
Q40112065 | Fusion of cyclophilin A to Fv1 enables cyclosporine-sensitive restriction of human and feline immunodeficiency viruses. |
Q37566736 | Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1. |
Q39800870 | Generation of a human immunodeficiency virus type 1 chronically infected monkey B cell line expressing low levels of endogenous TRIM5alpha |
Q33548284 | Generation of human TRIM5alpha mutants with high HIV-1 restriction activity |
Q38632835 | HIV Nuclear Entry: Clearing the Fog. |
Q35902681 | HIV Restriction Factors and Mechanisms of Evasion |
Q26995784 | HIV restriction in quiescent CD4⁺ T cells |
Q35826918 | HIV-1 capsid-targeting domain of cleavage and polyadenylation specificity factor 6 |
Q27023387 | HIV-1 reverse transcription |
Q30603540 | HIV-1 uncoating is facilitated by dynein and kinesin 1 |
Q37705207 | HIV-1 uncoating: connection to nuclear entry and regulation by host proteins |
Q34291026 | Hare TRIM5α restricts divergent retroviruses and exhibits significant sequence variation from closely related lagomorpha TRIM5 genes |
Q36483861 | Heat shock perturbs TRIM5alpha restriction of human immunodeficiency virus type 1 |
Q30431451 | Hexagonal assembly of a restricting TRIM5alpha protein |
Q40523370 | High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques. |
Q37252004 | Host Factors and HIV-1 Replication: Clinical Evidence and Potential Therapeutic Approaches |
Q36687748 | Host restriction factors blocking retroviral replication |
Q36548179 | Host restriction factors in retroviral infection: promises in virus-host interaction |
Q39638271 | Human Trim5α has additional activities that are uncoupled from retroviral capsid recognition |
Q37382519 | Human cellular restriction factors that target HIV-1 replication |
Q37582948 | Human immunodeficiency virus, restriction factors, and interferon |
Q41690997 | Identification of capsid mutations that alter the rate of HIV-1 uncoating in infected cells |
Q34073576 | Immunogenetic Management Software: a new tool for visualization and analysis of complex immunogenetic datasets. |
Q24656091 | Independent evolution of an antiviral TRIMCyp in rhesus macaques |
Q36491115 | Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species |
Q33997880 | Innate immune recognition and activation during HIV infection |
Q34561070 | Insights into cellular factors that regulate HIV-1 replication in human cells |
Q92703239 | Interplay between Intrinsic and Innate Immunity during HIV Infection |
Q52650219 | Intracellular Antiviral Immunity. |
Q37899341 | Intracellular defenses against HIV, viral evasion and novel therapeutic approaches |
Q28659575 | Intrinsic cellular defenses against human immunodeficiency viruses |
Q91862920 | K63-Linked Ubiquitin Is Required for Restriction of HIV-1 Reverse Transcription and Capsid Destabilization by Rhesus TRIM5α |
Q28472652 | Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection |
Q36401357 | Lentiviral gene therapy against human immunodeficiency virus type 1, using a novel human TRIM21-cyclophilin A restriction factor. |
Q28546614 | Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration |
Q42638839 | Mechanisms of late restriction induced by an endogenous retrovirus. |
Q36949816 | Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha |
Q37399926 | Molecular evolution of the antiretroviral TRIM5 gene. |
Q34149568 | Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction |
Q39207567 | Murine double minute 2 as a modulator of retroviral restrictions mediated by TRIM5alpha |
Q37292441 | New developments in the induction and antiviral effectors of type I interferon |
Q27667494 | Novel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein |
Q33624690 | Novel approaches to inhibiting HIV-1 replication. |
Q96126837 | Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus |
Q35018068 | Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity |
Q41285425 | Overexpression of feline tripartite motif-containing 25 interferes with the late stage of feline leukemia virus replication |
Q36154893 | Ovine TRIM5α can restrict visna/maedi virus. |
Q57469890 | PF74 Reinforces the HIV-1 Capsid To Impair Reverse Transcription-Induced Uncoating |
Q38886122 | Polyubiquitin chain-dependent protein degradation in TRIM30 cytoplasmic bodies |
Q39601777 | Porcine endogenous retroviruses PERV A and A/C recombinant are insensitive to a range of divergent mammalian TRIM5alpha proteins including human TRIM5alpha |
Q39691970 | Potent lentiviral restriction by a synthetic feline TRIM5 cyclophilin A fusion. |
Q35142600 | Potent restriction of HIV-1 and SIVmac239 replication by African green monkey TRIM5α. |
Q30276687 | Primate TRIM5 proteins form hexagonal nets on HIV-1 capsids |
Q33331396 | Primate lentiviral Vpx commandeers DDB1 to counteract a macrophage restriction |
Q33337129 | Proteasomal degradation of TRIM5alpha during retrovirus restriction |
Q35101356 | Proteasome inhibition reveals that a functional preintegration complex intermediate can be generated during restriction by diverse TRIM5 proteins |
Q39907814 | Proteasome inhibitors enhance bacteriophage lambda (lambda) mediated gene transfer in mammalian cells. |
Q35921992 | RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin. |
Q35689590 | RING domain mutations uncouple TRIM5α restriction of HIV-1 from inhibition of reverse transcription and acceleration of uncoating |
Q37830048 | Recent insights into the mechanism and consequences of TRIM5α retroviral restriction |
Q38727566 | Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets |
Q30543944 | Recruitment and dynamics of proteasome association with rhTRIM5α cytoplasmic complexes during HIV-1 infection |
Q60046078 | Restriction Factors: From Intrinsic Viral Restriction to Shaping Cellular Immunity Against HIV-1 |
Q91937602 | Restriction of HIV-1 and other retroviruses by TRIM5 |
Q34641314 | Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein |
Q37629123 | Restriction of feline retroviruses: lessons from cat APOBEC3 cytidine deaminases and TRIM5alpha proteins. |
Q36673325 | Restriction of foamy viruses by primate Trim5alpha |
Q24630459 | Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha |
Q37911028 | Restriction of the felid lentiviruses by a synthetic feline TRIM5-CypA fusion. |
Q37895742 | Retroviral restriction and dependency factors in primates and carnivores |
Q63976830 | Retrovirus Restriction by TRIM5α: RINGside at a Cage Fight |
Q39137377 | Retrovirus restriction by TRIM5 proteins requires recognition of only a small fraction of viral capsid subunits |
Q51003294 | Reverse Transcription of Retroviruses and LTR Retrotransposons. |
Q40255729 | Reverse transcription complex: the key player of the early phase of HIV replication |
Q28477489 | Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces |
Q84985844 | Rhesus monkey TRIM5α has distinct HIV-1 restriction activity among different mammalian cell lines |
Q39473622 | Rhesus monkey TRIM5α represses HIV-1 LTR promoter activity by negatively regulating TAK1/TAB1/TAB2/TAB3-complex-mediated NF-κB activation |
Q35831267 | Role of Human TRIM5α in Intrinsic Immunity |
Q35140364 | Role of TRIM5α RING domain E3 ubiquitin ligase activity in capsid disassembly, reverse transcription blockade, and restriction of simian immunodeficiency virus |
Q33826918 | Role of human immunodeficiency virus type 1 integrase in uncoating of the viral core |
Q91447788 | S100A9 regulates porcine reproductive and respiratory syndrome virus replication by interacting with the viral nucleocapsid protein |
Q30417737 | SIV replication in human cells |
Q40185026 | SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells |
Q35859394 | SJP-L-5, a novel small-molecule compound, inhibits HIV-1 infection by blocking viral DNA nuclear entry |
Q38998244 | Second generation imaging of nuclear/cytoplasmic HIV-1 complexes |
Q39754032 | Simian TRIM5alpha proteins reduce replication of herpes simplex virus |
Q33724266 | Stabilized human TRIM5α protects human T cells from HIV-1 infection |
Q38058751 | Structure and function of the SPRY/B30.2 domain proteins involved in innate immunity |
Q38008141 | Studies of endogenous retroviruses reveal a continuing evolutionary saga |
Q35261541 | Systems-biology approaches to discover anti-viral effectors of the human innate immune response |
Q24607229 | TRIM family proteins and their emerging roles in innate immunity |
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Q36760097 | TRIM22 inhibits influenza A virus infection by targeting the viral nucleoprotein for degradation |
Q36433878 | TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling. |
Q36014646 | TRIM5 and the Regulation of HIV-1 Infectivity |
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Q33990615 | TRIM5alpha disrupts the structure of assembled HIV-1 capsid complexes in vitro |
Q36694073 | TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction. |
Q24304062 | TRIM5α and Species Tropism of HIV/SIV |
Q24296803 | TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions |
Q35531415 | TRIM5α does not affect simian immunodeficiency virus SIV(mac251) replication in vaccinated or unvaccinated Indian rhesus macaques following intrarectal challenge exposure |
Q36000845 | TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription. |
Q36523956 | TRIM5α-Mediated Ubiquitin Chain Conjugation Is Required for Inhibition of HIV-1 Reverse Transcription and Capsid Destabilization |
Q35240160 | TRIM79α, an interferon-stimulated gene product, restricts tick-borne encephalitis virus replication by degrading the viral RNA polymerase |
Q45875539 | Targeting TRIM5α in HIV Cure Strategies for the CRISPR-Cas9 Era. |
Q37928913 | Targeting human immunodeficiency virus type 1 assembly, maturation and budding. |
Q36974663 | The TRIM5alpha B-box 2 domain promotes cooperative binding to the retroviral capsid by mediating higher-order self-association |
Q40075519 | The TRIMendous Role of TRIMs in Virus-Host Interactions |
Q39187298 | The V86M mutation in HIV-1 capsid confers resistance to TRIM5α by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import |
Q34456506 | The carboxyl-terminus of human immunodeficiency virus type 2 circulating recombinant form 01_AB capsid protein affects sensitivity to human TRIM5α. |
Q21245199 | The cell biology of HIV-1 and other retroviruses |
Q37970939 | The cell biology of TRIM5α. |
Q36848296 | The control of viral infection by tripartite motif proteins and cyclophilin A. |
Q40134522 | The design of artificial retroviral restriction factors |
Q35784739 | The human TRIM5alpha restriction factor mediates accelerated uncoating of the N-tropic murine leukemia virus capsid |
Q36707747 | The innate antiviral response: new insights into a continuing story |
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Q36745786 | The retroviral restriction factor TRIM5alpha |
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Q33877357 | The specificity of TRIM5 alpha-mediated restriction is influenced by its coiled-coil domain |
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Q36978951 | Virus-specific effects of TRIM5α(rh) RING domain functions on restriction of retroviruses. |
Q36446606 | Visualization of a proteasome-independent intermediate during restriction of HIV-1 by rhesus TRIM5alpha |
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