Projection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture

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Projection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture is …
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scholarly articleQ13442814

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P819ADS bibcode2006PNAS..103.3627A
P356DOI10.1073/PNAS.0509929103
P8608Fatcat IDrelease_bukk6zlr3zd5jatkryictf37xq
P3181OpenCitations bibliographic resource ID4226991
P932PMC publication ID1450133
P698PubMed publication ID16501047
P5875ResearchGate publication ID7276608

P2093author name stringStephen G Aller
Vinzenz M Unger
P2860cites workMRC image processing programsQ30424665
Ximdisp--A visualization tool to aid structure determination from electron microscope imagesQ30677845
Projection structure of NhaA, a secondary transporter from Escherichia coli, at 4.0 A resolutionQ33866894
Three-dimensional structure of the ion-coupled transport protein NhaA.Q33886837
Structure of the multidrug resistance efflux transporter EmrE from Escherichia coliQ34299369
Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A.Q34347544
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammalsQ34393336
RETRACTED: Structure of the ABC transporter MsbA in complex with ADP.vanadate and lipopolysaccharideQ34418541
Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic developmentQ36238864
Analysis of electron microscope images and electron diffraction patterns of thin crystals of phi 29 connectors in ice.Q36734678
The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cellsQ40539956
Three-dimensional structure of a recombinant gap junction membrane channelQ40972332
The open pore conformation of potassium channelsQ42677283
Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function.Q42956952
Three-dimensional structure of a bacterial oxalate transporter.Q44064226
The copper transporter CTR1 regulates cisplatin uptake in Saccharomyces cerevisiaeQ44187748
Mutation analysis of copper transporter genes in patients with ethylmalonic encephalopathy, mitochondriopathies and copper deficiency phenotypesQ44289091
Three-dimensional structure of P-glycoprotein: the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state.Q51822776
The mechanism of copper uptake mediated by human CTR1: a mutational analysis.Q52566106
Projection structure of a gap junction membrane channel at 7 A resolutionQ71958817
A C-terminal domain of the membrane copper pump Ctr1 exchanges copper(I) with the copper chaperone Atx1Q74467644
The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and SelectivityQ22337058
hCTR1: a human gene for copper uptake identified by complementation in yeastQ24314292
Biochemical characterization and subcellular localization of human copper transporter 1 (hCTR1)Q24534124
The N-terminus of the human copper transporter 1 (hCTR1) is localized extracellularly, and interacts with itselfQ24535607
Structural insights into the assembly of the type III secretion needle complex.Q24547949
Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolutionQ27625023
Structural determinants of water permeation through aquaporin-1Q27627493
X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivityQ27637382
The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanismQ27638959
Crystal structure of bacterial multidrug efflux transporter AcrBQ27639761
Structure and gating mechanism of the acetylcholine receptor poreQ27641514
Structure and mechanism of the lactose permease of Escherichia coliQ27641768
Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coliQ27641769
A transmembrane helix dimer: structure and implicationsQ27735013
Molecular characterization of hCTR1, the human copper uptake proteinQ28201165
Biochemical characterization of the human copper transporter Ctr1Q28209180
Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channelQ28215839
Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptakeQ28216178
Identification of methionine-rich clusters that regulate copper-stimulated endocytosis of the human Ctr1 copper transporterQ28246079
Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channelQ28291702
Stable plasma membrane levels of hCTR1 mediate cellular copper uptakeQ28301247
The copper transporter CTR1 provides an essential function in mammalian embryonic developmentQ28366364
Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transportersQ29616590
Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutaseQ29619948
Structure of a glutamate transporter homologue from Pyrococcus horikoshiiQ30032687
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectcopperQ753
identical protein bindingQ14762994
Solute carrier family 31 member 1Q21111959
P304page(s)3627-3632
P577publication date2006-02-24
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleProjection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture
P478volume103

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