The orphan nuclear receptor, COUP-TF II, inhibits myogenesis by post-transcriptional regulation of MyoD function: COUP-TF II directly interacts with p300 and myoD

scientific article

The orphan nuclear receptor, COUP-TF II, inhibits myogenesis by post-transcriptional regulation of MyoD function: COUP-TF II directly interacts with p300 and myoD is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/26.23.5501
P932PMC publication ID147985
P698PubMed publication ID9826778
P5875ResearchGate publication ID13459511

P50authorVittorio SartorelliQ74615347
P2093author name stringY Hamamori
P Bailey
G E Muscat
P2860cites workLigand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressorQ24311650
Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamilyQ24312858
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300Q24324556
Recruitment of octamer transcription factors to DNA by glucocorticoid receptorQ24522497
Two receptor interaction domains in the corepressor, N-CoR/RIP13, are required for an efficient interaction with Rev-erbA alpha and RVR: physical association is dependent on the E region of the orphan receptorsQ24543959
Retinoid X receptor-COUP-TF interactions modulate retinoic acid signalingQ24563064
MyoD and the regulation of myogenesis by helix-loop-helix proteinsQ24634287
Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2CQ24647260
Structural determinants of nuclear receptor assembly on DNA direct repeatsQ27730227
Determinants for selective RAR and TR recognition of direct repeat HREs.Q46177795
Sequence and characterization of a coactivator for the steroid hormone receptor superfamilyQ27860465
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptorsQ27860552
Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivoQ27934206
A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulatorsQ27937976
COUP-TF and Sp1 interact and cooperate in the transcriptional activation of the human immunodeficiency virus type 1 long terminal repeat in human microglial cellsQ28255786
bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave outQ28258591
Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptorQ28261331
Differential roles of p300 and PCAF acetyltransferases in muscle differentiationQ28276083
Retinoic acid receptors and muscle b-HLH proteins: partners in retinoid-induced myogenesisQ28278483
A transcriptional co-repressor that interacts with nuclear hormone receptorsQ28289864
Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivoQ28298865
Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repressionQ28513708
Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylaseQ29547913
Role of CBP/P300 in nuclear receptor signallingQ29616443
COUP orphan receptors are negative regulators of retinoic acid response pathwaysQ30984728
p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcriptionQ33886012
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiationQ34355279
Transcriptional repression by the orphan steroid receptor RVR/Rev-erb beta is dependent on the signature motif and helix 5 in the E region: functional evidence for a biological role of RVR in myogenesisQ34610873
The corepressor N-CoR and its variants RIP13a and RIP13Delta1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70.Q34669136
Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalonQ35234826
Ligand binding was acquired during evolution of nuclear receptorsQ36240368
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptorsQ36701525
SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimersQ36813375
The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.Q37630287
Structure of the retinoid X receptor alpha DNA binding domain: a helix required for homodimeric DNA bindingQ38319122
Muscle-specific transcriptional activation by MyoDQ38334158
A nuclear hormone receptor corepressor mediates transcriptional silencing by receptors with distinct repression domains.Q38352823
TFIID (TBP) stabilizes the binding of MyoD to its DNA site at the promoter and MyoD facilitates the association of TFIIB with the preinitiation complexQ39723706
MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiationQ40016694
Functional domains of the human orphan receptor ARP-1/COUP-TFII involved in active repression and transrepressionQ40023148
Identification of a regulatory function for an orphan receptor in muscle: COUP-TF II affects the expression of the myoD gene family during myogenesisQ40393701
Chicken ovalbumin upstream promoter transcription factor (COUP-TF): expression during mouse embryogenesis.Q40455182
Regulation of vertebrate muscle differentiation by thyroid hormone: the role of the myoD gene family.Q40524026
Chicken ovalbumin upstream promoter-transcription factors and their regulation.Q40971221
Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphataseQ41073701
Constitutive expression of the orphan receptor, Rev-erbA alpha, inhibits muscle differentiation and abrogates the expression of the myoD gene familyQ41263862
p53-independent expression of p21Cip1 in muscle and other terminally differentiating cellsQ41368682
Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.Q41368691
Transcriptional repression by COUP-TF II is dependent on the C-terminal domain and involves the N-CoR variant, RIP13delta1.Q42450537
Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiationQ42808711
An evolutionary conserved COUP-TF binding element in a neural-specific gene and COUP-TF expression patterns support a major role for COUP-TF in neural developmentQ46045989
P433issue23
P407language of work or nameEnglishQ1860
P304page(s)5501-5510
P577publication date1998-12-01
P1433published inNucleic Acids ResearchQ135122
P1476titleThe orphan nuclear receptor, COUP-TF II, inhibits myogenesis by post-transcriptional regulation of MyoD function: COUP-TF II directly interacts with p300 and myoD
P478volume26

Reverse relations

cites work (P2860)
Q37286912Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors
Q37140791An overview of nuclear receptor coregulators involved in cerebellar development
Q37395711COUP-TFII regulates satellite cell function and muscular dystrophy
Q33268239Chicken ovalbumin upstream promoter transcription factor II regulates uncoupling protein 3 gene transcription in Phodopus sungorus
Q46784297Comparative genomics identifies genes mediating cardiotoxicity in the embryonic zebrafish heart
Q55411718Computational analysis of mRNA expression profiling in the inner ear reveals candidate transcription factors associated with proliferation, differentiation, and deafness.
Q24537650Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development
Q46464226Copulation in C. elegans males requires a nuclear hormone receptor.
Q33784603Dysregulation of nuclear receptor COUP-TFII impairs skeletal muscle development
Q40266495E1A is the component of the MHC class I enhancer complex that mediates HDAC chromatin repression in adenovirus-12 tumorigenic cells
Q22008577Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD
Q24537062Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK.
Q35802800Gene silencing by nuclear orphan receptors
Q38161336Involvement of COUP-TFs in Cancer Progression
Q30841576Molecular pathogenesis of congenital diaphragmatic hernia revealed by exome sequencing, developmental data, and bioinformatics
Q64246785Nr2f-dependent allocation of ventricular cardiomyocyte and pharyngeal muscle progenitors
Q35202790Nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) modulates mesenchymal cell commitment and differentiation.
Q37337890Nuclear receptor regulation of stemness and stem cell differentiation.
Q36003602Orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) protein negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation through suppressing runt-related gene 2 (Runx2) activity
Q36529528Orphan nuclear receptors: therapeutic opportunities in skeletal muscle.
Q38131639Regulatory potential of COUP-TFs in development: stem/progenitor cells
Q46152847Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development
Q96136676Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment
Q24559775The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development
Q37123139Transcriptomic profile adaptations following exposure of equine satellite cells to nutriactive phytochemical gamma-oryzanol.

Search more.