| scholarly article | Q13442814 |
| P2093 | author name string | G Serin | |
| L E Maquat | |||
| J D Black | |||
| R Aronoff | |||
| A Gersappe | |||
| P2860 | cites work | Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII | Q22010667 |
| Mammalian orthologues of a yeast regulator of nonsense transcript stability | Q24313065 | ||
| The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs | Q24324097 | ||
| Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein | Q24336236 | ||
| SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast | Q24554452 | ||
| Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions | Q24606339 | ||
| A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm | Q24609182 | ||
| Site-directed mutagenesis by overlap extension using the polymerase chain reaction | Q27860503 | ||
| Relationship between yeast polyribosomes and Upf proteins required for nonsense mRNA decay | Q27930632 | ||
| Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover | Q27931028 | ||
| Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen | Q27933721 | ||
| A factor required for nonsense-mediated mRNA decay in yeast is exported from the nucleus to the cytoplasm by a nuclear export signal sequence. | Q27934076 | ||
| The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif | Q27936654 | ||
| The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm | Q27938663 | ||
| Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein | Q27940268 | ||
| Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway | Q28352632 | ||
| A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance | Q29615731 | ||
| A perfect message: RNA surveillance and nonsense-mediated decay | Q29616125 | ||
| Initiation of translation in prokaryotes and eukaryotes | Q29618237 | ||
| The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon | Q29618647 | ||
| Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm | Q29618907 | ||
| Eukaryote-specific domains in translation initiation factors: implications for translation regulation and evolution of the translation system | Q31805213 | ||
| Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway | Q33285641 | ||
| Structure and functions of nucleolin. | Q33536089 | ||
| At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation | Q33778146 | ||
| Identification of an additional gene required for eukaryotic nonsense mRNA turnover | Q33837730 | ||
| The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein | Q33886877 | ||
| Human beta-globin mRNAs that harbor a nonsense codon are degraded in murine erythroid tissues to intermediates lacking regions of exon I or exons I and II that have a cap-like structure at the 5' termini | Q33938355 | ||
| Interaction between Nmd2p and Upf1p is required for activity but not for dominant-negative inhibition of the nonsense-mediated mRNA decay pathway in yeast | Q34361018 | ||
| Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm | Q34361461 | ||
| smg-7 is required for mRNA surveillance in Caenorhabditis elegans. | Q34606258 | ||
| When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells. | Q34693550 | ||
| Mof4-1 is an allele of the UPF1/IFS2 gene which affects both mRNA turnover and -1 ribosomal frameshifting efficiency | Q35911278 | ||
| A splicing-dependent regulatory mechanism that detects translation signals | Q35913215 | ||
| The upf3 protein is a component of the surveillance complex that monitors both translation and mRNA turnover and affects viral propagation. | Q36215365 | ||
| A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells | Q36283006 | ||
| Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance | Q36666048 | ||
| Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position | Q40370573 | ||
| Gene products that promote mRNA turnover in Saccharomyces cerevisiae | Q40654686 | ||
| Nonsense surveillance in lymphocytes? | Q41716349 | ||
| Purification and characterization of the Upf1 protein: a factor involved in translation and mRNA degradation | Q41840016 | ||
| ATP is a cofactor of the Upf1 protein that modulates its translation termination and RNA binding activities | Q42284161 | ||
| Defects in RNA splicing and the consequence of shortened translational reading frames | Q42590534 | ||
| Binary specification of nonsense codons by splicing and cytoplasmic translation | Q42647080 | ||
| mRNA surveillance in mammalian cells: the relationship between introns and translation termination | Q42805590 | ||
| Polysome-associated mRNAs are substrates for the nonsense-mediated mRNA decay pathway in Saccharomyces cerevisiae | Q43206028 | ||
| mRNA surveillance by the Caenorhabditis elegans smg genes | Q72234045 | ||
| Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon | Q72613072 | ||
| The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay | Q73958589 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| Caenorhabditis elegans | Q91703 | ||
| Saccharomyces cerevisiae | Q719725 | ||
| P304 | page(s) | 209-23 | |
| P577 | publication date | 2001-01-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4) | |
| P478 | volume | 21 |
| Q24805903 | A GFP-based reporter system to monitor nonsense-mediated mRNA decay |
| Q41792371 | A UPF3-mediated regulatory switch that maintains RNA surveillance |
| Q35296745 | A highly conserved region essential for NMD in the Upf2 N-terminal domain |
| Q30727507 | A natural classification of ribonucleases |
| Q38812591 | A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy. |
| Q34342871 | A post-translational regulatory switch on UPF1 controls targeted mRNA degradation |
| Q24298385 | A protein interaction framework for human mRNA degradation |
| Q34182070 | A role for nonsense-mediated mRNA decay in plants: pathogen responses are induced in Arabidopsis thaliana NMD mutants |
| Q28185435 | A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex |
| Q53383708 | Aberrant mRNA transcripts and the nonsense-mediated decay proteins UPF2 and UPF3 are enriched in the Arabidopsis nucleolus. |
| Q35741768 | An alternative branch of the nonsense-mediated decay pathway |
| Q29547273 | An extensive network of coupling among gene expression machines |
| Q54303567 | Analysis of nonsense-mediated mRNA decay in mammalian cells. |
| Q24303422 | Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay |
| Q50336107 | CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells |
| Q35950217 | Caenorhabditis elegans SMG-2 selectively marks mRNAs containing premature translation termination codons |
| Q34075898 | Cell type-dependent gene regulation by Staufen2 in conjunction with Upf1. |
| Q43419038 | Chapter 13. Identifying substrates of mRNA decay factors by a combined RNA interference and DNA microarray approach. |
| Q24293459 | Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1. |
| Q37371781 | Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways |
| Q24530107 | Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells |
| Q38765438 | DNA substrate recognition and processing by the full-length human UPF1 helicase |
| Q51440900 | DRN and TRAMP degrade specific and overlapping aberrant mRNAs formed at various stages of mRNP biogenesis in Saccharomyces cerevisiae. |
| Q34160063 | Disorders with similar clinical phenotypes reveal underlying genetic interaction: SATB2 acts as an activator of the UPF3B gene. |
| Q36114054 | Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6 |
| Q24291673 | Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20 |
| Q24293763 | Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA |
| Q41895895 | Functional characterization of Upf1 targets in Schizosaccharomyces pombe |
| Q24315053 | Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation |
| Q38346636 | Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA decay pathways in yeast |
| Q30488459 | HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA. |
| Q24291647 | Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay |
| Q24317402 | Human proline-rich nuclear receptor coregulatory protein 2 mediates an interaction between mRNA surveillance machinery and decapping complex |
| Q37574287 | Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1. |
| Q35942822 | Identification of Interactions in the NMD Complex Using Proximity-Dependent Biotinylation (BioID). |
| Q34883031 | Identification of SMG6 cleavage sites and a preferred RNA cleavage motif by global analysis of endogenous NMD targets in human cells |
| Q24316203 | Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay |
| Q24529924 | Identification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta |
| Q28550086 | In Silico Analysis of the Structural and Biochemical Features of the NMD Factor UPF1 in Ustilago maydis |
| Q36119318 | Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies |
| Q91173483 | Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP |
| Q27661724 | Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex |
| Q24791079 | Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway |
| Q36717854 | Inter-kingdom conservation of mechanism of nonsense-mediated mRNA decay |
| Q24310826 | Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast |
| Q28078564 | Interactions between the HIV-1 Unspliced mRNA and Host mRNA Decay Machineries |
| Q37336107 | Intra- and intermolecular regulatory interactions in Upf1, the RNA helicase central to nonsense-mediated mRNA decay in yeast |
| Q36149408 | Intranuclear binding in space and time of exon junction complex and NXF1 to premRNPs/mRNPs in vivo |
| Q35097691 | Looking at mRNA decay pathways through the window of molecular evolution |
| Q58583775 | Lost in Translation: Ribosome-Associated mRNA and Protein Quality Controls |
| Q24535973 | Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex |
| Q38568755 | Mechanism, factors, and physiological role of nonsense-mediated mRNA decay. |
| Q29616012 | Messenger-RNA-binding proteins and the messages they carry |
| Q47069297 | Molecular identification of smg-4, required for mRNA surveillance in C. elegans |
| Q24297542 | Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2 |
| Q33717750 | Multifaceted Regulation of Gene Expression by the Apoptosis- and Splicing-Associated Protein Complex and Its Components |
| Q24612060 | Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation |
| Q41792418 | NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity |
| Q24314864 | NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA |
| Q57060205 | NMD-degradome sequencing reveals ribosome-bound intermediates with 3'-end non-templated nucleotides |
| Q35602865 | NMD: At the crossroads between translation termination and ribosome recycling |
| Q37783315 | NMD: RNA biology meets human genetic medicine |
| Q37675497 | NMD: a multifaceted response to premature translational termination |
| Q37325822 | NMD: multitasking between mRNA surveillance and modulation of gene expression |
| Q36052204 | Navigating without a road map |
| Q35296033 | New insights into the formation of active nonsense-mediated decay complexes. |
| Q51034747 | Nonsense in the testis: multiple roles for nonsense-mediated decay revealed in male reproduction. |
| Q40552071 | Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay. |
| Q89068594 | Nonsense-Mediated mRNA Decay Begins Where Translation Ends |
| Q28082699 | Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story |
| Q33739414 | Nonsense-mediated RNA decay regulation by cellular stress: implications for tumorigenesis. |
| Q36969583 | Nonsense-mediated decay of ash1 nonsense transcripts in Saccharomyces cerevisiae |
| Q43920331 | Nonsense-mediated decay: assaying for effects on selenoprotein mRNAs |
| Q47821036 | Nonsense-mediated decay: linking a basic cellular process to human disease. |
| Q35148086 | Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question |
| Q40005465 | Nonsense-mediated mRNA decay (NMD) mechanisms |
| Q38768738 | Nonsense-mediated mRNA decay factor Upf2 exists in both the nucleoplasm and the cytoplasm |
| Q24671607 | Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways |
| Q34417077 | Nonsense-mediated mRNA decay in Saccharomyces cerevisiae |
| Q35133712 | Nonsense-mediated mRNA decay in Saccharomyces cerevisiae: a quality control mechanism that degrades transcripts harboring premature termination codons |
| Q37622077 | Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors |
| Q28077157 | Nonsense-mediated mRNA decay in humans at a glance |
| Q28207318 | Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities |
| Q36498954 | Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease |
| Q38591386 | Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes |
| Q35133708 | Nonsense-mediated mRNA decay: insights into mechanism from the cellular abundance of human Upf1, Upf2, Upf3, and Upf3X proteins |
| Q27015298 | Nonsense-mediated mRNA decay: inter-individual variability and human disease |
| Q26750271 | Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact |
| Q29616134 | Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics |
| Q92991777 | Nuclear UPF1 Is Associated with Chromatin for Transcription-Coupled RNA Surveillance |
| Q27930252 | Nuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense-mediated mRNA decay pathway in yeast |
| Q35081663 | Perturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice |
| Q27684654 | Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5–SMG7 and SMG6 |
| Q24300529 | Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7 |
| Q38823597 | Physiological and pathophysiological role of nonsense-mediated mRNA decay |
| Q37210527 | Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region |
| Q40119962 | Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins |
| Q36149583 | Process or perish: quality control in mRNA biogenesis |
| Q37246101 | Processing bodies are not required for mammalian nonsense-mediated mRNA decay |
| Q93138965 | Quality and quantity control of gene expression by nonsense-mediated mRNA decay |
| Q34156109 | Quality control of mRNA function |
| Q45846483 | RNA decay, evolution, and the testis |
| Q34664936 | RNA surveillance by nuclear scanning? |
| Q36287491 | RNAi and RNA-based regulation of immune system function |
| Q36748147 | Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay |
| Q38048705 | Regulation of nonsense-mediated mRNA decay |
| Q37426756 | Remodeling of the pioneer translation initiation complex involves translation and the karyopherin importin beta |
| Q27935545 | Role for Upf2p phosphorylation in Saccharomyces cerevisiae nonsense-mediated mRNA decay |
| Q37075694 | SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs |
| Q37349465 | SMG-1 is a phosphatidylinositol kinase-related protein kinase required for nonsense-mediated mRNA Decay in Caenorhabditis elegans |
| Q34463782 | SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A. |
| Q34416344 | Stop making nonSense: the C. elegans smg genes |
| Q27680677 | Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2 |
| Q27640680 | Structural and functional insights into the human Upf1 helicase core |
| Q36783622 | The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay |
| Q57166264 | The Nucleolus |
| Q28596579 | The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA |
| Q55514032 | The RNA surveillance proteins UPF1, UPF2 and SMG6 affect HIV-1 reactivation at a post-transcriptional level. |
| Q35108985 | The Upf-dependent decay of wild-type PPR1 mRNA depends on its 5'-UTR and first 92 ORF nucleotides |
| Q29619835 | The cap-to-tail guide to mRNA turnover |
| Q42152373 | The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3' end. |
| Q27014757 | The dharma of nonsense-mediated mRNA decay in mammalian cells |
| Q38670016 | The exon junction complex as a node of post-transcriptional networks |
| Q24537105 | The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling |
| Q29616054 | The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay |
| Q40176218 | The feedback control of UPF3 is crucial for RNA surveillance in plants |
| Q37375181 | The mammalian nonsense-mediated mRNA decay pathway: to decay or not to decay! Which players make the decision? |
| Q37013877 | The multiple lives of NMD factors: balancing roles in gene and genome regulation |
| Q34582806 | The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts |
| Q28248816 | The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3 |
| Q38615446 | UPF1 helicase promotes TSN-mediated miRNA decay. |
| Q38027956 | UPF1 involvement in nuclear functions |
| Q33381591 | UPF1, a conserved nonsense-mediated mRNA decay factor, regulates cyst wall protein transcripts in Giardia lamblia |
| Q64097221 | UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond |
| Q24339439 | Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2 |
| Q47250656 | Upf proteins: highly conserved factors involved in nonsense mRNA mediated decay |
| Q27938201 | Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast |
| Q24300691 | Y14 and hUpf3b form an NMD-activating complex |
| Q27938110 | Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit |
| Q43203528 | hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay |
| Q35011995 | mRNA degradation machines in eukaryotic cells |
| Q38469185 | mRNA metabolism and neuronal disease |
| Q34169710 | mRNA quality control: Marking the message for life or death. |
| Q34245372 | mRNA turnover |
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