Modulation of CRX transactivation activity by phosducin isoforms

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Modulation of CRX transactivation activity by phosducin isoforms is …
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P356DOI10.1128/MCB.20.14.5216-5226.2000
P8608Fatcat IDrelease_zzzqyflxnrhodk7kxdbmb7x6pu
P932PMC publication ID85970
P698PubMed publication ID10866677
P5875ResearchGate publication ID12451520

P2093author name stringX Zhu
C M Craft
P2860cites workCone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptorQ24311359
Determination of the G beta gamma-binding domain of phosducin. A regulatable modulator of G beta gamma signalingQ24337214
Phosducin-like protein: an ethanol-responsive potential modulator of guanine nucleotide-binding protein functionQ24564134
Mammalian Sug1 and c-Fos in the nuclear 26S proteasomeQ24630118
Heterodimerization of Msx and Dlx homeoproteins results in functional antagonismQ24646334
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
Elements regulating the transcription of human interstitial retinoid-binding protein (IRBP) gene in cultured retinoblastoma cellsQ28137747
OTX2 homeodomain protein binds a DNA element necessary for interphotoreceptor retinoid binding protein gene expressionQ28198028
Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genesQ28255968
Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degenerationQ28258792
Phosducin-like protein (PhLP), a regulator of G beta gamma function, interacts with the proteasomal protein SUG1Q28268289
Molecular cloning of the cone-rod homeobox gene (Crx) from the rat and its temporal expression pattern in the retina under a daily light-dark cycleQ47979398
Development of MEKA (phosducin), G beta, G gamma and S-antigen in the rat pineal gland and retina.Q48455947
Phosducin is a protein kinase A-regulated G-protein regulatorQ48456911
A major cis activator of the IRBP gene contains CRX-binding and Ret-1/PCE-I elementsQ48496583
Melatonin production: proteasomal proteolysis in serotonin N-acetyltransferase regulationQ48511345
Retinopathy and attenuated circadian entrainment in Crx-deficient mice.Q52537179
Transcriptional control: repression by local chromatin modification.Q52566165
A role for the proteasome in the light response of the timeless clock protein.Q52572922
Light-induced dephosphorylation of a 33K protein in rod outer segments of rat retinaQ53909856
NF-κB p105 Processing via the Ubiquitin-Proteasome PathwayQ57024845
Ubiquitinylation and ubiquitin-dependent proteolysis in vertebrate photoreceptors (rod outer segments). Evidence for ubiquitinylation of Gt and rhodopsinQ71143100
Ligand binding assays with recombinant proteins refolded on an affinity matrixQ72402928
A one-hour minipreparation technique for extraction of DNA-binding proteins from animal tissuesQ72426100
Erx, a novel retina-specific homeodomain transcription factor, can interact with Ret 1/PCEI sitesQ77293376
Interaction of phosducin and phosducin isoforms with a 26S proteasomal subunit, SUG1Q28279387
PhLPs and PhLOPs in the phosducin family of G beta gamma binding proteinsQ28290754
Protein kinase A phosphorylates retinal phosducin on serine 73 in situQ28296589
A pineal regulatory element (PIRE) mediates transactivation by the pineal/retina-specific transcription factor CRXQ28567311
Protein complex formation between Msx1 and Lhx2 homeoproteins is incompatible with DNA binding activityQ28590325
Phosducin-like protein (PhLP), a regulator of Gβγ function, interacts with the proteasomal protein SUG1Q29541844
Zebrafish interphotoreceptor retinoid-binding protein: differential circadian expression among cone subtypesQ30470324
Bovine arylalkylamine N-acetyltransferase activity correlated with mRNA expression in pineal and retinaQ30641113
Rat pineal gland phosducin: cDNA isolation, nucleotide sequence, and chromosomal assignment in the mouseQ33658879
Functional antagonism between the retinoic acid receptor and the viral transactivator BZLF1 is mediated by protein-protein interactionsQ33662787
Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding siteQ33923624
Differential expression of mRNA and protein encoding retinal and pineal S-antigen during the light/dark cycleQ34087049
The N terminus of phosducin is involved in binding of beta gamma subunits of G proteinQ34566626
Morphological, physiological, and biochemical changes in rhodopsin knockout miceQ34853562
Photoreceptors of the retina and pinealocytes of the pineal gland share common components of signal transductionQ35896888
Physical interaction between retinoic acid receptor and the oncoprotein myb inhibits retinoic acid-dependent transactivationQ36090901
Phosducin is a ubiquitous G-protein regulator.Q37328331
Retinoic acid is a negative regulator of AP-1-responsive genes.Q37546834
Inhibition of G-protein betagamma-subunit functions by phosducin-like protein.Q37710136
Regulation of phosducin phosphorylation in retinal rods by Ca2+/calmodulin-dependent adenylyl cyclaseQ37717974
A single cis-acting element in a short promoter segment of the gene encoding the interphotoreceptor retinoid-binding protein confers tissue-specific expression.Q38299666
Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormoneQ38339139
Transcriptional repression in developmentQ41066942
Active repression mechanisms of eukaryotic transcription repressorsQ41223932
Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugationQ41294965
A comparison of ubiquitin-dependent proteolysis of rod outer segment proteins in reticulocyte lysate and a retinal pigment epithelial cell lineQ41300555
The photoreceptor G-protein transducin (Gt) is a substrate for ubiquitin-dependent proteolysisQ41467646
Phosducin inhibits receptor phosphorylation by the beta-adrenergic receptor kinase in a PKA-regulated mannerQ41473059
Multiple redox regulation in NF-kappaB transcription factor activation.Q41679295
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptorQ41721253
Interactions of phosducin with defined G protein beta gamma-subunitsQ42064300
A novel complex from bovine visual cells of a 33,000-dalton phosphoprotein with beta- and gamma-transducin: purification and subunit structureQ42216249
Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation.Q42834166
Regulation of retinal cGMP cascade by phosducin in bovine rod photoreceptor cells. Interaction of phosducin and transducinQ45893624
Functional antagonism between oncoprotein c-Jun and steroid hormone receptorsQ46054403
Light-dependent regulation of the transcriptional activity of the mammalian gene for arrestinQ46085162
Interaction of phosducin-like protein with G protein betagamma subunitsQ46176657
Phosducin and betagamma-transducin interaction I: effects of post-translational modificationsQ46255986
The photoreceptor-specific 33 kDa phosphoprotein of mammalian retina: generation of monospecific antibodies and localization by immunocytochemistryQ46488034
Co-activators and co-repressors in the integration of transcriptional responsesQ46623959
The phosphorylation state of phosducin determines its ability to block transducin subunit interactions and inhibit transducin binding to activated rhodopsin.Q46671087
Retinal accumulation of the phosducin/T beta gamma and transducin complexes in developing normal mice and in mice and dogs with inherited retinal degenerationQ46731817
The DUG gene of Drosophila melanogaster encodes a structural and functional homolog of the S. cerevisiae SUG1 predicted ATPase associated with the 26S proteasome.Q47072545
P433issue14
P407language of work or nameEnglishQ1860
P304page(s)5216-26
P577publication date2000-07-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleModulation of CRX transactivation activity by phosducin isoforms
P478volume20