scholarly article | Q13442814 |
P356 | DOI | 10.1172/JCI21378 |
P8608 | Fatcat ID | release_lz4np2hlrrfspautaar6xxo7nu |
P932 | PMC publication ID | 524226 |
P698 | PubMed publication ID | 15520858 |
P5875 | ResearchGate publication ID | 8199383 |
P50 | author | Michael Kreuter | Q91561665 |
P2093 | author name string | Akio Shimizu | |
Arja Kaipainen | |||
Caroline Choi Kim | |||
Diane R Bielenberg | |||
Michael Klagsbrun | |||
Yasuhiro Hida | |||
P2860 | cites work | Neuropilin is a receptor for the axonal chemorepellent Semaphorin III | Q24310596 |
Neuropilin is a semaphorin III receptor | Q24310629 | ||
Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns | Q24311901 | ||
Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate | Q24315144 | ||
Isolation of the human semaphorin III/F gene (SEMA3F) at chromosome 3p21, a region deleted in lung cancer | Q24319164 | ||
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor | Q24321564 | ||
Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling | Q24534955 | ||
Interaction of endostatin with integrins implicated in angiogenesis | Q24545535 | ||
Semaphorin SEMA3F and VEGF have opposing effects on cell attachment and spreading | Q24550908 | ||
Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B | Q24555083 | ||
Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity | Q24677555 | ||
The biology of VEGF and its receptors | Q27860704 | ||
Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III | Q28114812 | ||
Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression | Q28139015 | ||
Human neuropilin-1 and neuropilin-2 map to 10p12 and 2q34, respectively | Q28144037 | ||
Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors | Q28145862 | ||
Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function | Q28189338 | ||
Neuropilin-1 in human colon cancer: expression, regulation, and role in induction of angiogenesis | Q28263245 | ||
Neuropilin-2 is a receptor for semaphorin IV: insight into the structural basis of receptor function and specificity | Q28291642 | ||
Semaphorin-neuropilin interactions underlying sympathetic axon responses to class III semaphorins | Q28293448 | ||
Semaphorins III and IV repel hippocampal axons via two distinct receptors | Q28589841 | ||
VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding | Q28646414 | ||
Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A. | Q33899576 | ||
Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis | Q34019593 | ||
Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish | Q34074705 | ||
Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells. | Q34091667 | ||
Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins | Q34099220 | ||
Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse. | Q34108858 | ||
Human Semaphorin 3B (SEMA3B) located at chromosome 3p21.3 suppresses tumor formation in an adenocarcinoma cell line | Q34111043 | ||
Neurovascular congruence results from a shared patterning mechanism that utilizes Semaphorin3A and Neuropilin-1. | Q34181370 | ||
Distinct 3p21.3 deletions in lung cancer and identification of a new human semaphorin | Q34382506 | ||
Intra-tumoural microvessel density in human solid tumours. | Q34708258 | ||
Lymphangiogenesis and cancer metastasis | Q34770288 | ||
The role of neuropilin in vascular and tumor biology. | Q35076249 | ||
Integrins: roles in cancer development and as treatment targets | Q35647842 | ||
Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival | Q35791518 | ||
The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm thick) skin melanoma. A quantitative histologic study | Q35819050 | ||
Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165. | Q36382096 | ||
Neuropilin-1 expression in osteogenic cells: down-regulation during differentiation of osteoblasts into osteocytes | Q38304213 | ||
The usefulness of tyrosinase in the immunohistochemical assessment of melanocytic lesions: a comparison of the novel T311 antibody (anti-tyrosinase) with S-100, HMB45, and A103 (anti-melan-A) | Q38462040 | ||
Semaphorin 3F gene from human 3p21.3 suppresses tumor formation in nude mice | Q40735367 | ||
Isolation and Characterization of Metastatic Variants from Human Transitional Cell Carcinoma Passaged by Orthotopic Implantation in Athymic Nude Mice | Q41289269 | ||
The formation of lymphatic vessels and its importance in the setting of malignancy | Q42025717 | ||
Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture | Q42615524 | ||
Critical determinants of melanoma metastasis | Q42679185 | ||
Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice | Q42819394 | ||
Enhanced tumorigenicity, melanogenesis, and metastases of a human malignant melanoma after subdermal implantation in nude mice | Q43504248 | ||
Redundant functions but temporal and regional regulation of two alternatively spliced isoforms of semaphorin 3F in the nervous system. | Q44627814 | ||
Epidermal hyperplasia overlying human melanoma correlates with tumour depth and angiogenesis | Q47733038 | ||
Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice | Q48042097 | ||
Semaphorin-3F is an inhibitor of tumor angiogenesis. | Q51051924 | ||
Abnormal lymphatic vessel development in neuropilin 2 mutant mice. | Q52114149 | ||
Establishment and characterization of seven Dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers. | Q52832843 | ||
Interaction of endostatin with integrins implicated in angiogenesis | Q56591884 | ||
A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice | Q70935075 | ||
Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase | Q73083817 | ||
Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial cell proliferation by a peptide corresponding to the exon 7-encoded domain of VEGF165 | Q73935037 | ||
Suppression of angiogenesis, tumorigenicity, and metastasis by human prostate cancer cells engineered to produce interferon-beta | Q74462148 | ||
Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3 | Q74489252 | ||
Endostatin induces endothelial cell apoptosis | Q77335987 | ||
Molecular regulation of UVB-induced cutaneous angiogenesis | Q77519518 | ||
Evidence for the causal role of endogenous interferon-alpha/beta in the regulation of angiogenesis, tumorigenicity, and metastasis of cutaneous neoplasms | Q78708143 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phenotype | Q104053 |
endothelium | Q111140 | ||
P304 | page(s) | 1260-1271 | |
P577 | publication date | 2004-11-01 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype | |
P478 | volume | 114 |
Q40817034 | A class III semaphorin (Sema3e) inhibits mouse osteoblast migration and decreases osteoclast formation in vitro. |
Q55005936 | A mechanism for semaphorin-induced apoptosis: DNA damage of endothelial and myogenic cells in primary cultures from skeletal muscle. |
Q34073272 | A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression |
Q28251368 | A perspective on the role of class III semaphorin signaling in central nervous system trauma |
Q47315180 | A quantitative method for screening and identifying molecular targets for nanomedicine |
Q34338200 | A role for neuropilins in the interaction between Schwann cells and meningeal cells |
Q30483797 | ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells |
Q33899627 | Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth. |
Q36887534 | Angiogenesis in brain tumours |
Q30388655 | Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors. |
Q34337052 | Assay development for the discovery of semaphorin 3B inducing agents from natural product sources. |
Q88950267 | CDK8 regulates the angiogenesis of pancreatic cancer cells in part via the CDK8-β-catenin-KLF2 signal axis |
Q38309271 | Chronic allograft rejection: a fresh look. |
Q37958927 | Class 3 semaphorins and their receptors in physiological and pathological angiogenesis |
Q36090884 | Class 3 semaphorins negatively regulate dermal lymphatic network formation. |
Q64276040 | Class-3 Semaphorins and Their Receptors: Potent Multifunctional Modulators of Tumor Progression |
Q44740278 | Correlation of neuropilin-1 overexpression to survival in acute myeloid leukemia |
Q37509064 | Current drug design to target the Semaphorin/Neuropilin/Plexin complexes |
Q47074135 | Cysteines in the neuropilin-2 MAM domain modulate receptor homooligomerization and signal transduction |
Q47739851 | Differential actions of VEGF-A isoforms on perichondrial angiogenesis during endochondral bone formation |
Q37382530 | Downregulation of Semaphorin-3F is associated with poor prognostic significance in osteosarcoma patients |
Q37427968 | Emerging roles of Semaphorins in the regulation of epithelial and endothelial junctions |
Q90511093 | Endothelium-targeted overexpression of krüppel-like factor 11 protects blood-brain barrier function after ischemic brain injury |
Q24321689 | Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4) |
Q37484796 | Expression of Semaphorin 3F and Its Receptors in Epithelial Ovarian Cancer, Fallopian Tubes, and Secondary Müllerian Tissues |
Q36421453 | Expression of semaphorin 3A and neuropilin 1 with clinicopathological features and survival in human tongue cancer |
Q51956797 | Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus. |
Q42045919 | Ezetimibe is an inhibitor of tumor angiogenesis |
Q36249009 | Fugetaxis: active movement of leukocytes away from a chemokinetic agent. |
Q38056998 | Function of members of the neuropilin family as essential pleiotropic cell surface receptors. |
Q37223217 | GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2. |
Q37236779 | Gating of Sema3E/PlexinD1 signaling by neuropilin-1 switches axonal repulsion to attraction during brain development. |
Q35962330 | Genetic Identification of SEMA3F as an Antilymphangiogenic Metastasis Suppressor Gene in Head and Neck Squamous Carcinoma |
Q33797591 | Gleevec/imatinib, an ABL2 kinase inhibitor, protects tumor and endothelial cells from semaphorin-induced cytoskeleton collapse and loss of cell motility |
Q54620202 | High-resolution mass spectrometric analysis of the secretome from mouse lung endothelial progenitor cells. |
Q33647661 | Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer |
Q33826605 | Hypercholesterolemia induces angiogenesis and accelerates growth of breast tumors in vivo |
Q35533847 | Hypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2. |
Q33820517 | Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F |
Q36131507 | Increased smooth muscle contractility in mice deficient for neuropilin 2. |
Q52936238 | Infantile hemangioma-derived stem cells and endothelial cells are inhibited by class 3 semaphorins. |
Q42977967 | Inflammation and Lymphedema Are Exacerbated and Prolonged by Neuropilin 2 Deficiency |
Q39817646 | Inhibitory effects of epigallocatechin-3 gallate, a polyphenol in green tea, on tumor-associated endothelial cells and endothelial progenitor cells |
Q34762113 | Integration of genotypic and phenotypic screening reveals molecular mediators of melanoma-stromal interaction. |
Q33962267 | Krüpple-like factors in the central nervous system: novel mediators in stroke |
Q58042812 | Loss of sensory and noradrenergic innervation in benign colorectal adenomatous polyps - a putative role of semaphorins 3F and 3A |
Q26825144 | Lymphangiogenesis and metastasis--a closer look at the neuropilin/semaphorin3 axis |
Q34972161 | Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates |
Q42773855 | Mechanistic basis for the potent anti-angiogenic activity of semaphorin 3F |
Q33390446 | Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation |
Q35836025 | Merlin/NF2 regulates angiogenesis in schwannomas through a Rac1/semaphorin 3F-dependent mechanism |
Q41692560 | Molecular profiling of the "plexinome" in melanoma and pancreatic cancer |
Q96304812 | NRP2 as an Emerging Angiogenic Player; Promoting Endothelial Cell Adhesion and Migration by Regulating Recycling of α5 Integrin |
Q36561939 | Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein |
Q37588549 | Neuropilin-2 Is upregulated in lung cancer cells during TGF-β1-induced epithelial-mesenchymal transition |
Q35634243 | Neuropilin-2: a novel biomarker for malignant melanoma? |
Q89587291 | Neuropilin: Handyman and Power Broker in the Tumor Microenvironment |
Q64275592 | Neuropilins in the Context of Tumor Vasculature |
Q38161356 | Neuropilins: a new target for cancer therapy |
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Q37079862 | Neuropilins: novel targets for anti-angiogenesis therapies |
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Q37702693 | Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression |
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Q35615400 | Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells |
Q54790387 | Plexin C1, a receptor for semaphorin 7a, inactivates cofilin and is a potential tumor suppressor for melanoma progression. |
Q36851512 | Potential therapeutic strategies for lymphatic metastasis |
Q34255775 | RORα suppresses breast tumor invasion by inducing SEMA3F expression |
Q47956039 | Refuting the hypothesis that semaphorin-3f/neuropilin-2 exclude blood vessels from the cap mesenchyme in the developing kidney |
Q35834072 | Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo |
Q36274124 | Regulation of soluble neuropilin 1, an endogenous angiogenesis inhibitor, in liver development and regeneration |
Q37217481 | Reprogramming multipotent tumor cells with the embryonic neural crest microenvironment |
Q53545593 | SEMA3F prevents metastasis of colorectal cancer by PI3K-AKT-dependent down-regulation of the ASCL2-CXCR4 axis. |
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