HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy (scientific article)

Human immunodeficiency virus (HIV) envelope binds to CXCR4 independently of CD4, and binding can be enhanced by interaction with soluble CD4 or by HIV envelope deglycosylation.

Q28646878

HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors

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Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins

Q33564269

Lymphotropic virions affect chemokine receptor-mediated neural signaling and apoptosis: implications for human immunodeficiency virus type 1-associated dementia

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Induction of interleukin-1 and tumor necrosis factor alpha in brain cultures by human immunodeficiency virus type 1

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HIV-1 infected mononuclear phagocyte secretory products affect neuronal physiology leading to cellular demise: relevance for HIV-1-associated dementia.

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Pathways to neuronal injury and apoptosis in HIV-associated dementia.

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Tumor necrosis factor-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV central nervous system infection

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Microglia as a source and target of cytokines

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The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes

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Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1.

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gp120-induced neurotoxicity in hippocampal pyramidal neuron cultures: protective action of TGF-beta1.

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Mitogenic effects of interleukin-5 on microglia.

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Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

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Quinolinic acid production is related to macrophage tropic isolates of HIV-1.

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Human immunodeficiency virus type 1 Vpr induces apoptosis in human neuronal cells

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T cell-replacing factor (TRF)/interleukin 5 (IL-5): molecular and functional properties

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Molecular and cellular biology of eosinophil differentiation factor (interleukin-5) and its effects on human and mouse B cells

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Development of a human neuronal cell model for human immunodeficiency virus (HIV)-infected macrophage-induced neurotoxicity: apoptosis induced by HIV type 1 primary isolates and evidence for involvement of the Bcl-2/Bcl-xL-sensitive intrinsic apopto

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AIDS dementia: a review of the literature.

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HIV-1 Associated Dementia: Clinical Features and Pathogenesis

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Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome

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c-Jun N-terminal kinase pathway mediates Lactacystin-induced cell death in a neuronal differentiated Neuro2a cell line

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Lentiviral expression of HIV-1 Vpr induces apoptosis in human neurons

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Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.

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Production of interleukin-5 by mouse astrocytes and microglia in culture

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Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1.

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Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

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NFkappaB activation, TNF-alpha expression, and apoptosis in the AIDS-Dementia-Complex.

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CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity

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Apoptosis of Neuro2a cells induced by lysosphingolipids with naturally occurring stereochemical configurations.

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Ethanol strongly potentiates apoptosis induced by HIV-1 proteins in primary human brain microvascular endothelial cells

Q44264146

Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis

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Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of l -cysteine

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Caspase cascades in human immunodeficiency virus-associated neurodegeneration.

Q45732507

Effects of human immunodeficiency virus and colony-stimulating factors on the production of interleukin 6 and tumor necrosis factor alpha by monocyte/macrophages

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Memantine prevents HIV coat protein-induced neuronal injury in vitro

Q45976515

The HIV-1 gp120 causes ultrastructural changes typical of apoptosis in the rat cerebral cortex

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Programmed cell death in brains of HIV-1-positive AIDS and pre-AIDS patients

Q71486304

Differences among HIV-1 variants in their ability to elicit secretion of TNF-alpha

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Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function

Q78003712

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

apoptotic process

Q14599311

P304

page(s)

7070-5

P577

publication date

2004-05-04

P1433

published in

Proceedings of the National Academy of Sciences of the United States of America

Q1146531

P1476

title

HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy

P478

volume

101

Reverse relations

cites work (P2860)

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P819	ADS bibcode	2004PNAS..101.7070X
P356	DOI	10.1073/PNAS.0304859101
P932	PMC publication ID	406467
P698	PubMed publication ID	15103018
P5875	ResearchGate publication ID	8601941