Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria

scientific article

Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1973PNAS...70.2276B
P356DOI10.1073/PNAS.70.8.2276
P3181OpenCitations bibliographic resource ID1293473
P932PMC publication ID433717
P698PubMed publication ID4209515
P5875ResearchGate publication ID18955304

P2093author name stringJ Davies
R Benveniste
P2860cites workNonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNAQ24562997
Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivativesQ28236791
Enzymic acetylation of aminoglycoside antibiotics by Excherichia coli carrying an R factorQ34223788
Enzymatic Phosphorylation of Streptomycin by Extracts of Streptomycin-producing Strains of StreptomycesQ36818248
Aminoglycoside Antibiotics: Inactivation by Phosphorylation inEscherichia coliCarrying R FactorsQ36820252
The problems of drug-resistant pathogenic bacteria. The origin of R factorsQ40000568
The Production of Penicillins in Soils and Seeds by Penicillium chrysogenum and the Role of Penicillin -Lactamase in the Ecology of Soil BacillusQ51227713
Molecular weights of ribosomal RNA in relation to evolutionQ52504512
Recovery of resistance (R) factors from a drug-free community.Q54685067
A Rapid Chemical Assay for GentamicinQ69158143
Gentamicin resistance in strains of Pseudomonas aeruginosa mediated by enzymatic N-acetylation of the deoxystreptamine moietyQ69371557
Transmissible multiple drug resistance in EnterobacteriaceaeQ70387758
Microbial transformation of antibiotics. II. Phosphorylation of lincomycin by Streptomyces speciesQ71224311
Microbial transformation of antibiotics. V. Clindamycin ribonucleotidesQ71752486
Microbial transformation of antibiotics. VI. Acylation of chloramphenicol by Streptomyces coelicolorQ71775474
Streptomycin biosynthesis and metabolism. Enzymatic phosphorylation of dihydrostreptobiosamine moieties of dihydro-streptomycin-(streptidino) phosphate and dihydrostreptomycin by Streptomyces extractsQ93694318
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectbacteriaQ10876
antibiotic resistanceQ380775
P304page(s)2276-80
P577publication date1973-08-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleAminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria
P478volume70

Reverse relations

cites work (P2860)
Q37598780A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin
Q40482486A comparison of DNA cleavage by the restriction enzymes SalPI and PstI
Q41950554A function of SmeDEF, the major quinolone resistance determinant of Stenotrophomonas maltophilia, is the colonization of plant roots
Q37340607A global view of antibiotic resistance
Q53942670A new antibiotic XK-62-2 (Sagamicin). I. Isolation, physicochemical and antibacterial properties.
Q42880013A path from predation to mutualism
Q33627287A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria.
Q69837970A second streptomycin resistance gene from Streptomyces griseus codes for streptomycin-3"-phosphotransferase. Relationships between antibiotic and protein kinases
Q34917476Activity of Three Aminoglycosides and Two Penicillins Against Four Species of Gram-Negative Bacilli
Q35010153Aminoglycoside-modifying enzyme of an antibiotic-producing bacterium acts as a determinant of antibiotic resistance in Escherichia coli
Q33745231Aminoglycoside-modifying enzymes
Q27658560An Antibiotic-Resistance Enzyme from a Deep-Sea Bacterium
Q59798774Antibiotic Resistance Mechanisms in Bacteria: Relationships Between Resistance Determinants of Antibiotic Producers, Environmental Bacteria, and Clinical Pathogens
Q39062989Antibiotic Resistant Superbugs: Assessment of the Interrelationship of Occurrence in Clinical Settings and Environmental Niches.
Q39592550Antibiotic Tolerance in Producer Organisms
Q35899972Antibiotic preparations contain DNA: a source of drug resistance genes?
Q40270998Antibiotic resistance in pathogenic and producing bacteria, with special reference to beta-lactam antibiotics
Q34138597Antibiotic resistance in the environment: a link to the clinic?
Q36660833Antibiotic resistance shaping multi-level population biology of bacteria
Q34304184Antibiotic resistance with particular reference to soil microorganisms
Q41711641Antibiotic resistance: it's bad, but why isn't it worse?
Q42382663Antibiotics and resistance: hand in hand?
Q40576787Antibiotics as related to endodontic therapy
Q36595848Antibiotics as selectors and accelerators of diversity in the mechanisms of resistance: from the resistome to genetic plasticity in the β-lactamases world
Q27025271Antibiotics that target protein synthesis
Q35880192Antimicrobial resistance gene delivery in animal feeds
Q59794432Antimicrobial usage by pastoralists in food animals in North-central Nigeria: The associated socio-cultural drivers for antimicrobials misuse and public health implications
Q37743270Avoidance of suicide in antibiotic-producing microbes
Q28073636Bacterial Multidrug Efflux Pumps: Much More Than Antibiotic Resistance Determinants
Q33837847Bacterial phylogeny structures soil resistomes across habitats
Q40270651Bacterial resistance to the tetracyclines
Q35221536Biosafety of kanamycin-resistant transgenic plants
Q92478635Blocking the Trigger: Inhibition of the Initiation of Bacterial Chromosome Replication as an Antimicrobial Strategy
Q35646654Bottlenecks in the transferability of antibiotic resistance from natural ecosystems to human bacterial pathogens.
Q91707780Bringing Community Ecology to Bear on the Issue of Antimicrobial Resistance
Q39785100Broad host range plasmids can invade an unexpectedly diverse fraction of a soil bacterial community
Q43079677Bulky "gatekeeper" residue changes the cosubstrate specificity of aminoglycoside 2''-phosphotransferase IIa.
Q37700168Call of the wild: antibiotic resistance genes in natural environments
Q48197696Characterization of an oxytetracycline-resistance gene, otrA, of Streptomyces rimosus
Q39471873Characterization of the chromosomal aac(6')-Iz gene of Stenotrophomonas maltophilia
Q39967204Cloning of the kanamycin resistance gene from a kanamycin-producing Streptomyces species.
Q40248188Comparative biology and evolution of bacteriophages.
Q90224212Comparison of Antibiotic Resistance Mechanisms in Antibiotic-Producing and Pathogenic Bacteria
Q64983927Comparison of Strategies to Overcome Drug Resistance: Learning from Various Kingdoms.
Q36259934Complete nucleotide sequence and transcription of ermF, a macrolide-lincosamide-streptogramin B resistance determinant from Bacteroides fragilis
Q93106724Comprehensive genomic analysis of an indigenous Pseudomonas pseudoalcaligenes degrading phenolic compounds
Q43245583Concentration-dependent activity of antibiotics in natural environments
Q36189828D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB
Q52297749DNA cloning in Streptomyces: resistance genes from antibiotic-producing species
Q33836545DNA in antibiotic preparations: absence of intact resistance genes
Q36336590Deoxyribonucleic acid sequence common to staphylococcal and streptococcal plasmids which specify erythromycin resistance
Q64100808Detecting and prioritizing biosynthetic gene clusters for bioactive compounds in bacteria and fungi
Q34264500Differential epigenetic compatibility of qnr antibiotic resistance determinants with the chromosome of Escherichia coli.
Q60951787Discovery of Potential Plant-Derived Peptide Deformylase (PDF) Inhibitors for Multidrug-Resistant Bacteria Using Computational Studies
Q33786634Dissemination of antibiotic resistance genes from antibiotic producers to pathogens
Q67550008Distribution of chloramphenicol acetyltransferase and chloramphenicol-3-acetate esterase among Streptomyces and Corynebacterium
Q58163572Ecological and Clinical Consequences of Antibiotic Subsistence by Environmental Microbes
Q39950742Effect of structural modifications on the biological properties of aminoglycoside antibiotics containing 2-deoxystreptamine.
Q35626332Efflux-mediated drug resistance in bacteria
Q33667581Emergence and spread of antibiotic resistance: setting a parameter space.
Q38657199Emerging resistance to aminoglycosides in lactic acid bacteria of food origin-an impending menace
Q34166324Environmental selection of antibiotic resistance genes
Q54637979Enzymes that inactivate antibiotics in transit to their targets
Q24490083Evolution of resistance to a last-resort antibiotic in Staphylococcus aureus via bacterial competition
Q54323173Evolutionary origin of aminoglycoside phosphotransferase resistance genes.
Q46307828Evolutionary origin of the class A and class C beta-lactamases
Q54483498Evolutionary relationships of the Bacillus licheniformis macrolide-lincosamide-streptogramin B resistance elements.
Q36579522Expression and regulation of lactose genes carried by plasmids
Q28775851Extrachromosomal elements as possible agents of adaptation and development
Q54518418Facilitation of horizontal transfer of antimicrobial resistance by transformation of antibiotic-induced cell-wall-deficient bacteria.
Q37267997Failure of the disk diffusion test to detect tobramycin resistance in kanamycin-resistant Escherichia coli strains
Q37461888Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste
Q35257970Friend turned foe: evolution of enterococcal virulence and antibiotic resistance
Q40105078Functional and kinetic analysis of the phosphotransferase CapP conferring selective self-resistance to capuramycin antibiotics.
Q28651559Functional characterization of bacteria isolated from ancient arctic soil exposes diverse resistance mechanisms to modern antibiotics
Q37389801Functional role of bacterial multidrug efflux pumps in microbial natural ecosystems
Q37868656Gene flow, mobile genetic elements and the recruitment of antibiotic resistance genes into Gram-negative pathogens
Q40871998Genes for a beta-lactamase, a penicillin-binding protein and a transmembrane protein are clustered with the cephamycin biosynthetic genes in Nocardia lactamdurans
Q54459066Genes for gentamicin-(3)-N-acetyl-transferases III and IV. II. Nucleotide sequences of three AAC(3)-III genes and evolutionary aspects.
Q48393805Genes for gentamicin-(3)-N-acetyltransferases III and IV: I. Nucleotide sequence of the AAC(3)-IV gene and possible involvement of an IS140 element in its expression
Q24677112Genetic and enzymatic basis of hygromycin B resistance in Escherichia coli
Q37943542Genome rearrangement and genetic instability in Streptomyces spp
Q66697225Gentamicin resistance in Staphylococcus aureus
Q38804628How Should We Be Determining Background and Baseline Antibiotic Resistance Levels in Agroecosystem Research?
Q36821705Impact of treated wastewater irrigation on antibiotic resistance in the soil microbiome
Q34760395Improved annotation of antibiotic resistance determinants reveals microbial resistomes cluster by ecology
Q41432638In vivo transfer of genetic information between gram-positive and gram-negative bacteria
Q39866177Inactivation of rifampin by Nocardia brasiliensis
Q37040064Induction of a stable sigma factor SigR by translation-inhibiting antibiotics confers resistance to antibiotics
Q34243333Influence of soil use on prevalence of tetracycline, streptomycin, and erythromycin resistance and associated resistance genes
Q38550551Inorganic nanoparticles engineered to attack bacteria
Q37970704Insights into antibiotic resistance through metagenomic approaches.
Q34102811Interactions among strategies associated with bacterial infection: pathogenicity, epidemicity, and antibiotic resistance
Q72378381Involvement of 16S ribosomal RNA in resistance of the aminoglycoside-producers Streptomyces tenjimariensis, Streptomyces tenebrarius and Micromonospora purpurea
Q40336942Involvement of the beta subunit of RNA polymerase in resistance to streptolydigin and streptovaricin in the producer organisms Streptomyces lydicus and Streptomyces spectabilis
Q38978646Julian Davies and the discovery of kanamycin resistance transposon Tn5.
Q34394999Mechanism of multiple aminoglycoside resistance of kasugamycin-producing Streptomyces kasugaensis MB273: involvement of two types of acetyltransferases in resistance to astromicin group antibiotics.
Q45046383Mechanism of resistance to thiostrepton in the producing-organism Streptomyces azureus
Q34406049Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.
Q37885402Metabolic regulation of antibiotic resistance.
Q38182909Metagenomic insights into the human gut resistome and the forces that shape it.
Q37472198Metagenomic profiling of historic Colorado Front Range flood impact on distribution of riverine antibiotic resistance genes
Q54459722Methylation of 16S ribosomal RNA and resistance to aminoglycoside antibiotics in clones of Streptomyces lividans carrying DNA from Streptomyces tenjimariensis.
Q41858834Microbes have the last word. A drastic re-evaluation of antimicrobial treatment is needed to overcome the threat of antibiotic-resistant bacteria
Q35363306Microbial glycosylation of erythromycin A.
Q47764759Molecular evidence for the ancient origin of the ribosomal protection protein that mediates tetracycline resistance in bacteria
Q37058913Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.
Q22255652Multidrug resistance in bacteria
Q40385075Natural antibiotic resistance and contamination by antibiotic resistance determinants: the two ages in the evolution of resistance to antimicrobials
Q39230397Next-generation approaches to understand and combat the antibiotic resistome.
Q36910633Novel resistance functions uncovered using functional metagenomic investigations of resistance reservoirs
Q33256453Novel streptomycin resistance gene from Mycobacterium fortuitum
Q36249835Nucleotide sequence analysis of the gene specifying the bifunctional 6'-aminoglycoside acetyltransferase 2"-aminoglycoside phosphotransferase enzyme in Streptococcus faecalis and identification and cloning of gene regions specifying the two activiti
Q34994129Nucleotide sequence and intracellular location of the product of the fosfomycin resistance gene from transposon Tn2921.
Q34704585Nucleotide sequence of IS110, an insertion sequence of Streptomyces coelicolor A3(2).
Q48383686Nucleotide sequence of a spectinomycin adenyltransferase AAD(9) determinant from Staphylococcus aureus and its relationship to AAD(3") (9).
Q37346955Nucleotide sequence of a streptomycete aminoglycoside phosphotransferase gene and its relationship to phosphotransferases encoded by resistance plasmids
Q36355047Nucleotide sequence of ermA, a macrolide-lincosamide-streptogramin B determinant in Staphylococcus aureus
Q40560165Nucleotide sequence of the hygromycin B phosphotransferase gene from Streptomyces hygroscopicus
Q35748622Occurrence and expression of imipemide (N-formimidoyl thienamycin) resistance in clinical isolates of coagulase-negative staphylococci.
Q29617791Origins and evolution of antibiotic resistance
Q54402263Patterns and distribution of aminoglycoside-acetylating enzymes in rapidly growing mycobacteria.
Q33722032Penicillin-binding proteins of Streptomyces cacaoi, Streptomyces olivaceus, and Streptomyces clavuligerus
Q35276250Phenotypic and genotypic heterogeneity of glycopeptide resistance determinants in gram-positive bacteria
Q59098631Plasmid-determined antibiotic synthesis and resistance in Streptomyces coelicolor
Q40161230Plasmid-determined resistance to antimicrobial drugs and toxic metal ions in bacteria
Q37187074Plasmid-encoded fosfomycin resistance
Q35646865Plasmid-mediated resistance to lincomycin by inactivation in Staphylococcus haemolyticus
Q42983819Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes
Q36198580Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine
Q50063564Polymorphism of antibiotic-inactivating enzyme driven by ecology expands the environmental resistome.
Q39620155Production of Polyene Macrolide Antibiotics
Q40090107Properties of ribosomes from Streptomyces erythreus and Streptomyces griseus
Q34933009Properties of the Ribosomes of Antibiotic Producers: Effects of Thiostrepton and Micrococcin on the Organisms Which Produce Them
Q37618069Purification and characterization of aminoglycoside phosphotransferase APH(6)-Id, a streptomycin-inactivating enzyme
Q33586916Purification, crystallization and preliminary X-ray analysis of Enterococcus casseliflavus aminoglycoside-2''-phosphotransferase-IVa
Q39737709Quinolone resistance: much more than predicted.
Q36586658RND multidrug efflux pumps: what are they good for?
Q42126936Regulation of an auxiliary, antibiotic-resistant tryptophanyl-tRNA synthetase gene via ribosome-mediated transcriptional attenuation
Q35284014Resistance of enterococci to glycopeptides
Q35905075Resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone antibiotics
Q34589857Resistance to tetracycline, macrolide-lincosamide-streptogramin, trimethoprim, and sulfonamide drug classes
Q42105495Ribosomal resistance in the gentamicin producer organism Micromonospora purpurea
Q36834702Rifampin phosphotransferase is an unusual antibiotic resistance kinase
Q26750462Self-resistance in Streptomyces, with Special Reference to β-Lactam Antibiotics
Q42867420Sequence and interspecies transfer of an aminoglycoside phosphotransferase gene (APH) of Bacillus circulans. Self-defence mechanism in antibiotic-producing organisms
Q39934474Sequence and transcriptional analysis of the Streptomyces glaucescens tcmAR tetracenomycin C resistance and repressor gene loci
Q41776282Source of phosphate in the enzymic reaction as a point of distinction among aminoglycoside 2''-phosphotransferases.
Q39775544Stimuli for the Production and Control of IgE in Rats
Q40256738Streptomycin Resistance in a Streptomycin-Producing Microorganism
Q27664447Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity
Q28242098Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases
Q45081437TetX is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics
Q24548472Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance
Q94948576Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance
Q34011054The 25 Years of Neomycin
Q30393373The Genomic Enzymology of Antibiotic Resistance
Q38851178The Prehistory of Antibiotic Resistance.
Q38134377The TetR family of regulators
Q38113563The antibiotic resistance "mobilome": searching for the link between environment and clinic.
Q29544028The antibiotic resistome: the nexus of chemical and genetic diversity
Q40636919The battle against emerging antibiotic resistance: should fluoroquinolones be used to treat children?
Q39847342The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A beta-lactamase of low enzymatic activity
Q47174251The complex resistomes of Paenibacillaceae reflect diverse antibiotic chemical ecologies
Q28533846The culturable soil antibiotic resistome: a community of multi-drug resistant bacteria
Q41249257The multifaceted roles of antibiotics and antibiotic resistance in nature
Q33320525The neglected intrinsic resistome of bacterial pathogens
Q34290827The role of ABC transporters in antibiotic-producing organisms: drug secretion and resistance mechanisms
Q51663672The role of natural environments in the evolution of resistance traits in pathogenic bacteria.
Q48396816The sequence of an antibiotic resistance gene from an antibiotic-producing bacterium. Homologies with transposon genes
Q33804392The shared antibiotic resistome of soil bacteria and human pathogens
Q35305715The soil resistome: a critical review on antibiotic resistance origins, ecology and dissemination potential in telluric bacteria.
Q41140006Transcriptional organization and regulation of an antibiotic export complex in the producing Streptomyces culture
Q42855849Transformation of Arthrobacter and studies on the transcription of the Arthrobacter ermA gene in Streptomyces lividans and Escherichia coli
Q35089352Transposition of R factor genes to bacteriophage lambda
Q36596014Transposition of a plasmid deoxyribonucleic acid sequence that mediates ampicillin resistance: identity of laboratory-constructed plasmids and clinical isolates
Q40281370Unstable mutation of beta-lactamase production in Streptomyces lavendulae
Q34058470Wastewater irrigation increases the abundance of potentially harmful gammaproteobacteria in soils in Mezquital Valley, Mexico
Q86386159What is a resistance gene? Ranking risk in resistomes
Q40221222Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines
Q33992884ZmaR, a novel and widespread antibiotic resistance determinant that acetylates zwittermicin A.
Q36814463Zwittermicin A resistance gene from Bacillus cereus
Q34498226vanI: a novel D-Ala-D-Lac vancomycin resistance gene cluster found in Desulfitobacterium hafniense

Search more.