The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2

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The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2 is …
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scholarly articleQ13442814

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P819ADS bibcode1995PNAS...92.3259T
P356DOI10.1073/PNAS.92.8.3259
P8608Fatcat IDrelease_wiyhepztk5cthbknxhkfjqplrm
P932PMC publication ID42145
P698PubMed publication ID7724549
P5875ResearchGate publication ID15473737

P50authorElliott D. KieffQ43399614
P2093author name stringD Reinberg
R Drapkin
X Tong
P2860cites workp44 and p34 subunits of the BTF2/TFIIH transcription factor have homologies with SSL1, a yeast protein involved in DNA repairQ24315493
Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genesQ24317228
Transcription factor IIE binds preferentially to RNA polymerase IIa and recruits TFIIH: a model for promoter clearanceQ24322625
The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factorQ24595611
Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH)Q24596052
Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53Q24609153
Structure and functional properties of human general transcription factor IIEQ28115411
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase IIQ28251866
Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase IIQ28646845
DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factorQ29619833
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene productQ29620442
Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformationQ34324039
Cloning of the 62-kilodalton component of basic transcription factor BTF2.Q34338584
The Epstein-Barr virus nuclear antigen 2 interacts with an EBNA2 responsive cis-element of the terminal protein 1 gene promoterQ34355226
Human xeroderma pigmentosum group D gene encodes a DNA helicaseQ34358690
Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23.Q34625121
Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE.Q34989722
Conserved sequence motifs in the small subunit of human general transcription factor TFIIE.Q34989727
The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding proteinQ35648541
Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1.Q35829475
The Epstein-Barr virus nuclear protein 2 acidic domain can interact with TFIIB, TAF40, and RPA70 but not with TATA-binding protein.Q35830605
The regulation of transcription by phosphorylationQ36377421
Epstein-Barr virus RNA. V. Viral RNA in a restringently infected, growth-transformed cell lineQ36507642
The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressorQ36652805
EBNA-2 transactivates a lymphoid-specific enhancer in the BamHI C promoter of Epstein-Barr virusQ36688330
Epstein-Barr virus nuclear protein 2 transactivates a cis-acting CD23 DNA elementQ36797190
Stable transfection of Epstein-Barr virus (EBV) nuclear antigen 2 in lymphoma cells containing the EBV P3HR1 genome induces expression of B-cell activation molecules CD21 and CD23.Q36801839
Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23Q36806063
The level of c-fgr RNA is increased by EBNA-2, an Epstein-Barr virus gene required for B-cell immortalizationQ36806641
Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1.Q36810617
Delineation of the cis-acting element mediating EBNA-2 transactivation of latent infection membrane protein expressionQ36828413
Non-immortalizing P3J-HR-1 Epstein-Barr virus: a deletion mutant of its transforming parent, JijoyeQ36927515
Mutational analysis of ERCC3, which is involved in DNA repair and transcription initiation: identification of domains essential for the DNA repair functionQ38307435
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repairQ38313225
Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein.Q40108807
The xeroderma pigmentosum group B protein ERCC3 produced in the baculovirus system exhibits DNA helicase activityQ40522217
The multifunctional TFIIH complex and transcriptional controlQ40592872
Regulation of TFIIH ATPase and kinase activities by TFIIE during active initiation complex formationQ41481294
Cell phenotype-dependent control of Epstein-Barr virus latent membrane protein 1 gene regulatory sequencesQ41543823
Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytesQ43679392
Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappaQ45781476
Initiation of transcription by RNA polymerase II: a multi-step process.Q52545755
Factors involved in specific transcription by mammalian RNA polymerase II. Identification and characterization of factor IIHQ55043488
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeastQ58318854
Binding of general transcription factor TFIIB to an acidic activating regionQ59058683
Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase IIQ59098636
Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of general transcription factor IIEQ70146901
An oligomeric form of the large subunit of transcription factor (TF) IIE activates phosphorylation of the RNA polymerase II carboxyl-terminal domain by TFIIHQ72108281
The function(s) of CAK, the p34cdc2-activating kinaseQ72545154
Genetic and biochemical evidence that EBNA 2 interaction with a 63-kDa cellular GTG-binding protein is essential for B lymphocyte growth transformation by EBVQ72756611
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectEpstein–Barr virusQ6900
molecular massQ182854
P304page(s)3259-63
P577publication date1995-04-11
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleThe 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2
P478volume92

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cites work (P2860)
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Q30981859BS69/ZMYND11 C-Terminal Domains Bind and Inhibit EBNA2.
Q33998709C-terminal region of EBNA-2 determines the superior transforming ability of type 1 Epstein-Barr virus by enhanced gene regulation of LMP-1 and CXCR7.
Q40883667CKII site in Epstein-Barr virus nuclear protein 2 controls binding to hSNF5/Ini1 and is important for growth transformation
Q38341023Characterization of the CBF2 binding site within the Epstein-Barr virus latency C promoter and its role in modulating EBNA2-mediated transactivation.
Q39682376Conserved region CR2 of Epstein-Barr virus nuclear antigen leader protein is a multifunctional domain that mediates self-association as well as nuclear localization and nuclear matrix association
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Q33851043Direct and indirect regulation of cytokine and cell cycle proteins by EBNA-2 during Epstein-Barr virus infection
Q35732134Direct interactions between Epstein-Barr virus leader protein LP and the EBNA2 acidic domain underlie coordinate transcriptional regulation
Q35862488EBNA-2 and EBNA-3C extensively and mutually exclusively associate with RBPJkappa in Epstein-Barr virus-transformed B lymphocytes
Q33850943EBNA-LP associates with cellular proteins including DNA-PK and HA95.
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Q38597233EBNA2 and Its Coactivator EBNA-LP.
Q37596895EBNA2 is required for protection of latently Epstein-Barr virus-infected B cells against specific apoptotic stimuli.
Q57186827EBNA2: A Viral Transcription Factor Essential for the Immortalization of Human B Lymphocytes by the Epstein-Barr Virus (EBV)
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Q34977875EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding
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Q24681418Epstein-Barr virus nuclear protein 2 (EBNA2) binds to a component of the human SNF-SWI complex, hSNF5/Ini1
Q33850964Epstein-Barr virus nuclear protein 2 has at least two N-terminal domains that mediate self-association
Q37156071Epstein-Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter
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Q27682610Structural and Functional Characterization of a Complex between the Acidic Transactivation Domain of EBNA2 and the Tfb1/p62 Subunit of TFIIH
Q33552252TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression
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Q35664999The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation
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Q35556199The transcriptional complexity of the TFIIH complex
Q47281234Transcription meets DNA repair at a PH domain
Q29618407p53: puzzle and paradigm

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