Factor XII: what does it contribute to our understanding of the physiology and pathophysiology of hemostasis & thrombosis

scientific article

Factor XII: what does it contribute to our understanding of the physiology and pathophysiology of hemostasis & thrombosis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/J.THROMRES.2009.11.028
P932PMC publication ID2851158
P698PubMed publication ID20022081
P5875ResearchGate publication ID40729581

P2093author name stringEvi Stavrou
Alvin H Schmaier
P2860cites workExpression and colocalization of cytokeratin 1 and urokinase plasminogen activator receptor on endothelial cellsQ24291096
Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulationQ24336585
Contaminated heparin associated with adverse clinical events and activation of the contact systemQ24619723
Defective thrombus formation in mice lacking coagulation factor XIIQ24646366
Increased activity of coagulation factor XII (Hageman factor) causes hereditary angioedema type IIIQ24671677
Amino acid sequence of the heavy chain of human alpha-factor XIIa (activated Hageman factor)Q28306231
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasisQ28508572
Factor XII interacts with the multiprotein assembly of urokinase plasminogen activator receptor, gC1qR, and cytokeratin 1 on endothelial cell membranesQ28628970
Amino acid sequence of human beta-factor XIIaQ28631018
Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulationQ30479254
Identification of a putative binding site for negatively charged surfaces in the fibronectin type II domain of human factor XII--an immunochemical and homology modeling approachQ30648422
Identification of cytokeratin 1 as a binding protein and presentation receptor for kininogens on endothelial cellsQ32081348
Combined cis-regulator elements as important mechanism affecting FXII plasma levelsQ34003352
Assignment of human coagulation factor XII (fXII) to chromosome 5 by cDNA hybridization to DNA from somatic cell hybridsQ34169566
Characterization of human blood coagulation factor XII cDNA. Prediction of the primary structure of factor XII and the tertiary structure of beta-factor XIIaQ34193071
WATERFALL SEQUENCE FOR INTRINSIC BLOOD CLOTTING.Q34257361
Polyphosphate modulates blood coagulation and fibrinolysis.Q34304738
Activation of blood clotting factors by microbial proteinasesQ34323403
Assembly of contact-phase factors on the surface of the human neutrophil membraneQ34329853
Characterization of the human blood coagulation factor XII gene. Intron/exon gene organization and analysis of the 5'-flanking regionQ34559748
Partial primary structure of bovine plasma fibronectin: Three types of internal homologyQ34707857
Increased vascular permeability in C1 inhibitor-deficient mice mediated by the bradykinin type 2 receptorQ34790892
Mapping of a putative surface-binding site of human coagulation factor XII.Q35145865
A familial hemorrhagic trait associated with a deficiency of a clot-promoting fraction of plasmaQ35282990
Modulation of the human monocyte binding site for monomeric immunoglobulin G by activated Hageman factorQ35592735
The autoactivation of rabbit Hageman factorQ36342996
Activation of the classical pathway of complement by Hageman factor fragmentQ36344568
The intrinsic pathway of coagulation: a target for treating thromboembolic disease?Q36771762
A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic diseaseQ37361142
Mitogenic effects of coagulation factor XII and factor XIIa on HepG2 cellsQ37513781
Factor XII-induced mitogenesis is mediated via a distinct signal transduction pathway that activates a mitogen-activated protein kinaseQ37712586
Inhibition of activated factor XII by antithrombin-heparin cofactorQ39404087
Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1.Q39447843
Cell surface interactions with extracellular materialsQ40157123
The binding and cleavage characteristics of human Hageman factor during contact activation. A comparison of normal plasma with plasmas deficient in factor XI, prekallikrein, or high molecular weight kininogenQ40690900
A monoclonal antibody recognizing an icosapeptide sequence in the heavy chain of human factor XII inhibits surface-catalyzed activationQ42058455
Orphan receptor hepatocyte nuclear factor-4 antagonizes estrogen receptor alpha-mediated induction of human coagulation factor XII geneQ42463195
Homozygosity for the C-->T polymorphism at nucleotide 46 in the 5' untranslated region of the factor XII gene protects from development of acute coronary syndromeQ43695448
Homozygosity of the T allele of the 46 C->T polymorphism in the F12 gene is a risk factor for ischemic stroke in the Spanish population.Q43771274
Activated factor XII levels and factor XII 46C>T genotype in relation to coronary artery calcification in patients with type 1 diabetes and healthy subjectsQ44019600
Association of the factor XII 46C>T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS studyQ44123484
John Hageman's factor and deep-vein thrombosis: Leiden thrombophilia StudyQ44652745
Human factor XII (Hageman factor) autoactivation by dextran sulfate. Circular dichroism, fluorescence, and ultraviolet difference spectroscopic studiesQ45205740
Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII.Q45279377
Dual role of collagen in factor XII-dependent thrombus formationQ46048146
Pathogenesis of serratial infection: activation of the Hageman factor-prekallikrein cascade by serratial proteaseQ46695250
Assembly, activation, and signaling by kinin-forming proteins on human vascular smooth muscle cells.Q53670507
Activation of blood clotting factors by microbial proteinasesQ56706175
Ordered adsorption of coagulation factor XII on negatively charged polymer surfaces probed by sum frequency generation vibrational spectroscopyQ57974758
Partial Identification of the Zn2+-Binding Sites in Factor XII and its Activation DerivativesQ59541864
The prevalence of factor XII deficiency in 103 orally anticoagulated outpatients suffering from recurrent venous and/or arterial thromboembolismQ67939877
Effect of negatively charged activating compounds on inactivation of factor XIIa by Cl inhibitorQ68826238
Epidermal growth factorQ68951248
Identification and characterization of a binding site for factor XIIa in the Apple 4 domain of coagulation factor XIQ70578873
Histidine residues are essential for the surface binding and autoactivation of human coagulation factor XIIQ70596348
Structure/function analysis of human factor XII using recombinant deletion mutants. Evidence for an additional region involved in the binding to negatively charged surfacesQ71149636
Monoclonal antibody F1 binds to the kringle domain of factor XII and induces enhanced susceptibility for cleavage by kallikreinQ71570789
Inhibition of activated Hageman factor and activated plasma thromboplastin antecedent by purified serum C1 inactivatorQ71585817
Contact activation in human plasma is triggered by zinc ion modulation of factor XII (Hageman factor)Q71607317
Molecular basis of estrogen regulation of Hageman factor XII gene expressionQ71813069
The cleavage and formation of activated human Hageman factor by autodigestion and by kallikreinQ71939378
Human factor XII binding to the glycoprotein Ib-IX-V complex inhibits thrombin-induced platelet aggregationQ73763204
Factor XII does not initiate prekallikrein activation on endothelial cellsQ74823530
The second exon-encoded factor XII region is involved in the interaction of factor XII with factor XI and does not contribute to the binding site for negatively charged surfacesQ77620528
The partial thromboplastin time with kaolin. A simple screening test for first stage plasma clotting factor deficienciesQ78981048
Role of hepatocyte nuclear factor 4alpha in control of blood coagulation factor gene expressionQ82152526
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectthrombosisQ261327
pathophysiologyQ1135939
P304page(s)210-5
P577publication date2010-03-01
P1433published inThrombosis ResearchQ15758741
P1476titleFactor XII: what does it contribute to our understanding of the physiology and pathophysiology of hemostasis & thrombosis
P478volume125

Reverse relations

cites work (P2860)
Q50683175A coupled chemo-fluidic computational model for thrombogenesis in infarcted left ventricles.
Q33737314A novel missense mutation in the factor XII gene in a litter of cats with factor XII deficiency
Q39539762A plasma proteolysis pathway comprising blood coagulation proteases
Q42601092Activated plasma coagulation β-Factor XII-induced vasoconstriction in rats
Q35561035Amidolytic, procoagulant, and activation-suppressing proteins produced by contact activation of blood factor XII in buffer solution.
Q37897474Arterial thrombus formation in cardiovascular disease
Q38688610Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation
Q55305378Coagulation Factor XII Levels and Intrinsic Thrombin Generation in Multiple Sclerosis.
Q42551076Contact activation of blood coagulation on a defined kaolin/collagen surface in a microfluidic assay
Q34473963Effect of nano-scale curvature on the intrinsic blood coagulation system
Q35535831Elevated D-dimers in attacks of hereditary angioedema are not associated with increased thrombotic risk.
Q34845482Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system
Q39886396FXIIa inhibitor rHA-Infestin-4: Safe thromboprotection in experimental venous, arterial and foreign surface-induced thrombosis
Q37636983Factor XII inhibition reduces thrombus formation in a primate thrombosis model
Q38860396Factor XII: form determines function
Q39322760Flow chamber and microfluidic approaches for measuring thrombus formation in genetic bleeding disorders
Q35145682Genetic divergence between populations of feral and domestic forms of a mosquito disease vector assessed by transcriptomics
Q35172654Heparan sulfate proteoglycans mediate factor XIIa binding to the cell surface
Q37876411Inherited disorders of blood coagulation
Q42922540Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer
Q38117200Kininogen-dependent antiphosphatidylethanolamine antibodies and autoantibodies to factor XII in patients with recurrent pregnancy losses
Q42011864Localization of Short-Chain Polyphosphate Enhances its Ability to Clot Flowing Blood Plasma.
Q46898343Molecular characterization of cat factor XII gene and identification of a mutation causing factor XII deficiency in a domestic shorthair cat colony
Q84784468Novel deleterious mutation in the F12 gene in a Korean family with severe coagulation factor XII deficiency
Q38014345Paradoxical thrombosis part 1: factor replacement therapy, inherited clotting factor deficiencies and prolonged APTT.
Q92670224Polyphosphate, Zn2+ and high molecular weight kininogen modulate individual reactions of the contact pathway of blood clotting
Q45933825Reduced Blood Coagulation on Roll-to-Roll, Shrink-Induced Superhydrophobic Plastics.
Q47900623Selective factor VIII activation by the tissue factor-factor VIIa-factor Xa complex
Q37665209Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer.
Q35905607The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats
Q38632499The contact activation and kallikrein/kinin systems: pathophysiologic and physiologic activities
Q26775616The factor XIIa blocking antibody 3F7: a safe anticoagulant with anti-inflammatory activities
Q38106741The kinin-kallikrein system: physiological roles, pathophysiology and its relationship to cancer biomarkers.
Q37853060The many faces of the contact pathway and their role in thrombosis
Q99623622The multifaceted role of plasminogen in inflammation
Q91768594Transferrin plays a central role in coagulation balance by interacting with clotting factors

Search more.