scholarly article | Q13442814 |
P50 | author | Guohui Wan | Q82663678 |
P2093 | author name string | Xinna Zhang | |
Xiongbin Lu | |||
Franklin G Berger | |||
Hexin Chen | |||
Sizolwenkosi Mlotshwa | |||
Vicki Vance | |||
P2860 | cites work | Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells | Q21195157 |
The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop | Q24297633 | ||
Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair | Q24297983 | ||
Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner | Q24336721 | ||
PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints | Q24527393 | ||
miR-15 and miR-16 induce apoptosis by targeting BCL2 | Q24536069 | ||
Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control | Q24537538 | ||
p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation | Q24596239 | ||
Prospective identification of tumorigenic breast cancer cells | Q24683474 | ||
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23 | Q28218453 | ||
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity | Q28218469 | ||
Causes and consequences of microRNA dysregulation in cancer | Q28258994 | ||
The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair | Q28278532 | ||
The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours | Q28279346 | ||
Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase | Q28283888 | ||
Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome | Q28283932 | ||
Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components | Q28290477 | ||
The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities | Q28297958 | ||
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells | Q29616498 | ||
Modulation of microRNA processing by p53 | Q29620776 | ||
A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D. | Q33294239 | ||
ATM is down-regulated by N-Myc-regulated microRNA-421. | Q33667539 | ||
Expression of a homeostatic regulator, Wip1 (wild-type p53-induced phosphatase), is temporally induced by c-Jun and p53 in response to UV irradiation | Q33726581 | ||
Stem cells in normal breast development and breast cancer | Q35548236 | ||
Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression | Q35568362 | ||
Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D | Q36326949 | ||
The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways. | Q36617172 | ||
Identification of tumor-initiating cells in a p53-null mouse model of breast cancer | Q36762011 | ||
Induction of PPM1D following DNA-damaging treatments through a conserved p53 response element coincides with a shift in the use of transcription initiation sites | Q37014644 | ||
Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition | Q39747969 | ||
Tiling path genomic profiling of grade 3 invasive ductal breast cancers | Q39868704 | ||
Increased wild-type p53-induced phosphatase 1 (Wip1 or PPM1D) expression correlated with downregulation of checkpoint kinase 2 in human gastric carcinoma | Q40096682 | ||
Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D. | Q40406429 | ||
MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response | Q41911349 | ||
Phosphorylation and degradation of MdmX is inhibited by Wip1 phosphatase in the DNA damage response | Q41967616 | ||
An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers | Q42458622 | ||
Association of 17q21-q24 gain in ovarian clear cell adenocarcinomas with poor prognosis and identification of PPM1D and APPBP2 as likely amplification targets | Q47848630 | ||
Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway | Q48022280 | ||
PPM1D is a potential target for 17q gain in neuroblastoma | Q52828743 | ||
The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis. | Q53595739 | ||
Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways | Q61849111 | ||
Stem cell characteristics of transplanted rat mammary clonogens | Q73018903 | ||
P433 | issue | 18 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA damage | Q5205747 |
P304 | page(s) | 7176-7186 | |
P577 | publication date | 2010-07-28 | |
P1433 | published in | Cancer Research | Q326097 |
P1476 | title | Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway | |
P478 | volume | 70 |