Noninvasive molecular imaging of c-Myc activation in living mice

scientific article

Noninvasive molecular imaging of c-Myc activation in living mice is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2010PNAS..10715892F
P356DOI10.1073/PNAS.1007443107
P3181OpenCitations bibliographic resource ID564682
P932PMC publication ID2936612
P698PubMed publication ID20713710
P5875ResearchGate publication ID45660024

P50authorHua Fan-MinogueQ48975673
P2093author name stringCarmel T Chan
Sanjiv S Gambhir
Tarik F Massoud
Ramasamy Paulmurugan
Dean W Felsher
Zhongwei Cao
P2860cites workMolecular imaging in drug developmentQ22122025
Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblastsQ24292464
Locating a protein-protein interaction in living cells via split Renilla luciferase complementationQ24300225
Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animalsQ24563431
Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivoQ24797399
Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibitionQ27633064
Nursing some sense out of Myc.Q33508688
Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformationQ33591386
The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenanceQ33913197
Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjectsQ34096497
Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategiesQ34388172
Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformationQ34536441
Modelling Myc inhibition as a cancer therapyQ34811008
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.Q35204486
Combinatorial library screening for developing an improved split-firefly luciferase fragment-assisted complementation system for studying protein-protein interactionsQ35414662
Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesisQ36007575
The c-Myc target gene networkQ36564217
The Myc oncoprotein as a therapeutic target for human cancerQ36578165
Mechanism of transcriptional activation by the Myc oncoproteinsQ36578696
Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological functionQ36580032
Why myc? An unexpected ingredient in the stem cell cocktailQ37121057
Reflecting on 25 years with MYC.Q37333643
Inhibition of in vitro transcription by a triplex-forming oligonucleotide targeted to human c-myc P2 promoterQ38294087
HIF-dependent antitumorigenic effect of antioxidants in vivoQ40085629
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cellsQ40572608
Monitoring Protein−Protein Interactions Using Split Synthetic Renilla Luciferase Protein-Fragment-Assisted ComplementationQ40653800
A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylationQ40795858
Imaging 26S proteasome activity and inhibition in living miceQ44486478
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.Q45861628
Association of C-MYC amplification with progression from the in situ to the invasive stage in C-MYC-amplified breast carcinomas.Q54757490
Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomasQ55670934
Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt's lymphoma expressing a conditional box II-deleted Myc proteinQ61053582
Ubiquitination of Myc: proteasomal degradation and beyondQ63407024
Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cellsQ72611015
P433issue36
P407language of work or nameEnglishQ1860
P304page(s)15892-15897
P577publication date2010-08-16
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleNoninvasive molecular imaging of c-Myc activation in living mice
P478volume107

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cites work (P2860)
Q34793715A c-Myc activation sensor-based high-throughput drug screening identifies an antineoplastic effect of nitazoxanide.
Q37905334Bioluminescence imaging: progress and applications
Q37577301Fast and robust reconstruction for fluorescence molecular tomography via a sparsity adaptive subspace pursuit method
Q36840350Fluorescence imaging of in vivo miR-124a-induced neurogenesis of neuronal progenitor cells using neuron-specific reporters
Q35072414Fluorescent biosensors for high throughput screening of protein kinase inhibitors.
Q43983077Imaging mouse cancer models in vivo using reporter transgenes
Q26851635Luciferase fragment complementation imaging in preclinical cancer studies
Q34687185MYC phosphorylation, activation, and tumorigenic potential in hepatocellular carcinoma are regulated by HMG-CoA reductase
Q41565021Noninvasive Imaging of Ras Activity by Monomolecular Biosensor Based on Split-Luciferase Complementary Assay
Q35945748Novel Bioluminescent Activatable Reporter for Src Tyrosine Kinase Activity in Living Mice
Q38227133Split-luciferase complementary assay: applications, recent developments, and future perspectives
Q38601645Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis.
Q36557855Targeting tumor metastases: Drug delivery mechanisms and technologies
Q26742117The Expanding Toolbox of In Vivo Bioluminescent Imaging
Q37871875The challenges of integrating molecular imaging into the optimization of cancer therapy.
Q35614045Visualizing protein partnerships in living cells and organisms

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