Interleukin 1 receptor antagonist. A new member of the interleukin 1 family

scientific article

Interleukin 1 receptor antagonist. A new member of the interleukin 1 family is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1172/JCI115453
P3181OpenCitations bibliographic resource ID2234822
P932PMC publication ID295645
P698PubMed publication ID1834696

P2093author name stringW P Arend
P2860cites workInterleukin-1 receptor antagonist activity of a human interleukin-1 inhibitorQ24294731
Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist proteinQ24296266
Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transductionQ24314529
Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptorQ24318599
Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanismQ28571336
Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonistQ33836551
Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonistQ34251859
Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitisQ34260899
Prostaglandin E2 and collagenase production by fibroblasts and synovial cells is regulated by urine-derived human interleukin 1 and inhibitor(s)Q34544134
Inhibition of interleukin 1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibodyQ36360942
A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in miceQ36360996
Interleukin-1 and interleukin-1 antagonismQ37081535
Conversion of the interleukin 1 receptor antagonist into an agonist by site-specific mutagenesisQ37456977
cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epitheliumQ37494553
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Interleukin 1-receptor antagonist blocks interleukin 1-induced sleep and feverQ40752402
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Human granulocyte-macrophage colony-stimulating factor plus phorbol myristate acetate stimulate a promyelocytic cell line to produce an IL-1 inhibitorQ40760248
Purification and characterization of a 26-kDa competitive inhibitor of interleukin 1.Q40764690
A human IL-1 alpha derivative which lacks prostaglandin E2 inducing activity and inhibits the activity of IL-1 through receptor competitionQ40767467
Specific interleukin-1 inhibitor in serum and urine of children with systemic juvenile chronic arthritisQ40792142
A urine inhibitor of interleukin 1 activity affects both interleukin 1 alpha and 1 beta but not tumor necrosis factor alpha.Q40794428
A urine inhibitor of interleukin 1 activity that blocks ligand binding.Q40794456
Inhibition of interleukin-1-induced synovitis and articular cartilage proteoglycan loss in the rabbit knee by recombinant human interleukin-1 receptor antagonist.Q41152837
Characterization of a specific 20- to 25-kD interleukin-1 inhibitor from cultured human lung macrophagesQ41720046
Production of a 26,000-dalton interleukin 1 inhibitor by human monocytes is regulated by granulocyte-macrophage colony-stimulating factorQ41742952
The intratracheal administration of endotoxin and cytokines. III. The interleukin-1 (IL-1) receptor antagonist inhibits endotoxin- and IL-1-induced acute inflammationQ41835332
C3 activation products correlate with antibodies to lipid A in pauciarticular juvenile arthritisQ43478050
A specific receptor antagonist for interleukin 1 prevents Escherichia coli ‐induced shock in rabbitsQ43740171
Heterogeneity of helper/inducer T lymphocytes. III. Responses of IL-2- and IL-4-producing (Th1 and Th2) clones to antigens presented by different accessory cells.Q44037744
Effects of immune complexes on production by human monocytes of interleukin 1 or an interleukin 1 inhibitorQ44598548
Induction of the interleukin 1 receptor antagonist protein by transforming growth factor-βQ58479946
Interleukin-1 receptor antagonist reduces mortality from endotoxin shockQ59092106
Biologic effects of an interleukin-1 receptor antagonist protein on interleukin-1–stimulated cartilage erosion and chondrocyte responsivenessQ67897217
Mouse IL-1 receptor antagonist protein. Molecular characterization, gene mapping, and expression of mRNA in vitro and in vivoQ67899769
IL-1ra ELISA: reduction and alkylation of synovial fluid eliminates interference by IgM rheumatoid factorsQ67900835
Production of interleukin-1 receptor antagonist and interleukin-1 beta by peripheral blood mononuclear cells is differentially regulatedQ67902109
IL-1 receptor antagonist and IL-1 beta production in human monocytes are regulated differentlyQ67902224
A point mutation uncouples human interleukin-1 beta biological activity and receptor bindingQ68413600
Natural and recombinant human IL-1 receptor antagonists block the effects of IL-1 on bone resorption and prostaglandin productionQ68435194
Modulation of the effects of interleukin-1 on glycosaminoglycan synthesis by the urine-derived interleukin-1 inhibitor, but not by interleukin-6Q68490165
Extension of the life-span of human endothelial cells by an interleukin-1 alpha antisense oligomerQ68568858
Human monocytes produce IL-1 and an inhibitor of IL-1 in response to two different signalsQ68903017
Production of interleukin-1 (IL-1) and a specific IL-1 inhibitor during human monocyte-macrophage differentiation: influence of GM-CSFQ69171062
A natural interleukin 1 (IL-1) inhibitor counteracts the inhibitory effect of IL-1 on insulin production in cultured rat pancreatic isletsQ93516981
An IL-1 inhibitor from human monocytes. Production and characterization of biologic propertiesQ93519955
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectinterleukinsQ194908
P304page(s)1445-51
P577publication date1991-11-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleInterleukin 1 receptor antagonist. A new member of the interleukin 1 family
P478volume88

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