Arabidopsis AtSerpin1, crystal structure and in vivo interaction with its target protease RESPONSIVE TO DESICCATION-21 (RD21)

scientific article

Arabidopsis AtSerpin1, crystal structure and in vivo interaction with its target protease RESPONSIVE TO DESICCATION-21 (RD21) is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.095075
P3181OpenCitations bibliographic resource ID1320537
P932PMC publication ID2859516
P698PubMed publication ID20181955

P50authorThomas H RobertsQ51009536
Paul CurmiQ42648512
P2093author name stringStephen J Harrop
Robert Fluhr
Olga Davydov
Nardy Lampl
Tom V Joss
Ofra Budai-Hadrian
P2860cites workSerpin genes AtSRP2 and AtSRP3 are required for normal growth sensitivity to a DNA alkylating agent in ArabidopsisQ21261961
Structure of a serpin-protease complex shows inhibition by deformationQ24290459
L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and LQ24531160
The involvement of cysteine proteases and protease inhibitor genes in the regulation of programmed cell death in plantsQ24543961
The Pfam protein families databaseQ24650035
Inhibition of tumorigenicity of the teratoma PC cell line by transfection with antisense cDNA for PC cell-derived growth factor (PCDGF, epithelin/granulin precursor)Q24652242
An overview of the serpin superfamilyQ24684030
The crystal structure of plasminogen activator inhibitor 2 at 2.0 A resolution: implications for serpin functionQ27618604
Coot: model-building tools for molecular graphicsQ27860505
On the size of the active site in proteases. I. PapainQ27860826
Phasercrystallographic softwareQ27860930
PHENIX: building new software for automated crystallographic structure determinationQ27861044
The CCP4 suite: programs for protein crystallographyQ27861090
Serpin structure, mechanism, and functionQ28217095
Purification of an autocrine growth factor homologous with mouse epithelin precursor from a highly tumorigenic cell lineQ28269288
Phosphorylation of histone h3 at serine 10 cannot account directly for the detachment of human heterochromatin protein 1gamma from mitotic chromosomes in plant cellsQ44024873
Arabidopsis protein disulfide isomerase-5 inhibits cysteine proteases during trafficking to vacuoles before programmed cell death of the endothelium in developing seedsQ44251369
AtCYS1, a cystatin from Arabidopsis thaliana, suppresses hypersensitive cell death.Q44465617
VEIDase is a principal caspase-like activity involved in plant programmed cell death and essential for embryonic pattern formation.Q44630766
A plant caspase-like protease activated during the hypersensitive response.Q44683690
Activity profiling of papain-like cysteine proteases in plantsQ44987619
Two Arabidopsis metacaspases AtMCP1b and AtMCP2b are arginine/lysine-specific cysteine proteases and activate apoptosis-like cell death in yeastQ45251284
Beta-lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana.Q46460108
Vacuolar processing enzyme is essential for mycotoxin-induced cell death in Arabidopsis thaliana.Q46618460
Metacaspase-8 modulates programmed cell death induced by ultraviolet light and H2O2 in Arabidopsis.Q46903274
A cysteine protease from maize isolated in a complex with cystatinQ47863269
Plasma and CSF serpins in Alzheimer disease and dementia with Lewy bodies.Q53388392
The proteolytic processing of seed storage proteins in Arabidopsis embryo cells starts in the multivesicular bodiesQ58478818
The native metastable fold of C1-inhibitor is stabilized by disulfide bondsQ72999594
Caspases and programmed cell death in the hypersensitive response of plants to pathogensQ77431805
Vacuolar processing enzyme is up-regulated in the lytic vacuoles of vegetative tissues during senescence and under various stressed conditionsQ78032665
Serpins of oat (Avena sativa) grain with distinct reactive centres and inhibitory specificityQ78297551
Induced expression of oryzain alpha gene encoding a cysteine proteinase under stress conditionsQ80088986
Crystal structure of human maspin, a serpin with antitumor properties: reactive center loop of maspin is exposed but constrainedQ80901117
Type II metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana cleave substrates after arginine and lysineQ28278397
Multifunctional role of plant cysteine proteinasesQ28284726
A slow maturation of a cysteine protease with a granulin domain in the vacuoles of senescing Arabidopsis leavesQ28366385
Genome-wide insertional mutagenesis of Arabidopsis thalianaQ29617345
Serpins: structure, function and molecular evolution.Q30333028
Serpin-ligand interactionsQ31034722
Chemical approaches for functionally probing the proteomeQ31092499
Inhibitory serpins from rye grain with glutamine as P1 and P2 residues in the reactive centerQ31864138
Human mesotrypsin exhibits restricted S1' subsite specificity with a strong preference for small polar side chainsQ33246025
Serpin1 of Arabidopsis thaliana is a suicide inhibitor for metacaspase 9.Q33259715
Differential gene expression for suicide-substrate serine proteinase inhibitors (serpins) in vegetative and grain tissues of barley.Q33339239
Inhibitory serpins from wheat grain with reactive centers resembling glutamine-rich repeats of prolamin storage proteins. Cloning and characterization of five major molecular formsQ33907645
Characterization of cucurbita maxima phloem serpin-1 (CmPS-1). A developmentally regulated elastase inhibitor.Q33915323
Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.Q33928073
Conformational properties of serine proteinase inhibitors (serpins) confer multiple pathophysiological rolesQ34201670
Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymaseQ34413644
The mechanism of Z alpha 1-antitrypsin accumulation in the liverQ34440939
Cucurbit phloem serpins are graft-transmissible and appear to be resistant to turnover in the sieve element-companion cell complex.Q34462514
Macromolecular crystal annealing: overcoming increased mosaicity associated with cryocrystallographyQ34474133
Shape-shifting serpins--advantages of a mobile mechanismQ34544636
A plant vacuolar protease, VPE, mediates virus-induced hypersensitive cell death.Q34549920
Serpins in plants and green algaeQ34722203
A unique mechanism for protein processing and degradation in Arabidopsis thaliana.Q35163800
A cut above the rest: the regulatory function of plant proteasesQ35934353
Temporal and spatial activation of caspase-like enzymes induced by self-incompatibility in Papaver pollen.Q36157011
Phloem sap proteins: their identities and potential roles in the interaction between plants and phloem-feeding insectsQ36403950
What happened to plant caspases?Q37084072
Exosite determinants of serpin specificityQ37343928
Heterologous expression of three plant serpins with distinct inhibitory specificitiesQ38352403
Are metacaspases caspases?Q39752566
Importance of the P2 glycine of antithrombin in target proteinase specificity, heparin activation, and the efficiency of proteinase trapping as revealed by a P2 Gly --> Pro mutation.Q40927256
Redundant proteolytic mechanisms process seed storage proteins in the absence of seed-type members of the vacuolar processing enzyme family of cysteine proteasesQ42687330
Constitutive activation of toll-mediated antifungal defense in serpin-deficient DrosophilaQ43169504
A proteinase-storing body that prepares for cell death or stresses in the epidermal cells of ArabidopsisQ43751031
Constitutive caspase-like machinery executes programmed cell death in plant cellsQ44023193
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
crystal structureQ895901
P304page(s)13550-60
P577publication date2010-04-30
P1433published inJournal of Biological ChemistryQ867727
P1476titleArabidopsis AtSerpin1, crystal structure and in vivo interaction with its target protease RESPONSIVE TO DESICCATION-21 (RD21)
P478volume285

Reverse relations

cites work (P2860)
Q441621081.45 Å resolution structure of SRPN18 from the malaria vector Anopheles gambiae
Q40752313A Kunitz-type protease inhibitor regulates programmed cell death during flower development in Arabidopsis thaliana
Q64073535A fungal substrate mimicking molecule suppresses plant immunity via an inter-kingdom conserved motif
Q46667736Activity profiling of vacuolar processing enzymes reveals a role for VPE during oomycete infection.
Q43468711Arabidopsis metacaspase 2d is a positive mediator of cell death induced during biotic and abiotic stresses
Q51424826Arabidopsis thaliana serpins AtSRP4 and AtSRP5 negatively regulate stress-induced cell death and effector-triggered immunity induced by bacterial effector AvrRpt2.
Q38981272AtSERPIN1 is an inhibitor of the metacaspase AtMC1-mediated cell death and autocatalytic processing in planta
Q33786493Calcium-dependent activation and autolysis of Arabidopsis metacaspase 2d.
Q91639098Chloroplast Protein Degradation in Senescing Leaves: Proteases and Lytic Compartments
Q34593862Genetic screen of a library of chimeric poxviruses identifies an ankyrin repeat protein involved in resistance to the avian type I interferon response.
Q33983210Identification of host genes involved in geminivirus infection using a reverse genetics approach
Q30383793Juggling jobs: roles and mechanisms of multifunctional protease inhibitors in plants.
Q37723699Maize IgE binding proteins: each plant a different profile?
Q28817865Major Cys protease activities are not essential for senescence in individually darkened Arabidopsis leaves
Q41830127Mining the Active Proteome of Arabidopsis thaliana.
Q43465792Molecular and immunological characterization of wheat Serpin (Tri a 33).
Q42929194Molecular contortionism - on the physical limits of serpin 'loop-sheet' polymers
Q37946960Natural substrates of plant proteases: how can protease degradomics extend our knowledge?
Q93067640Noncanonical interactions between serpin and β-amylase in barley grain improve β-amylase activity in vitro
Q51146726Overexpression of the aphid-induced serine protease inhibitor CI2c gene in barley affects the generalist green peach aphid, not the specialist bird cherry-oat aphid.
Q92564488Peptide-based protease inhibitors from plants
Q26766015Plant Proteases Involved in Regulated Cell Death
Q34187187Post-translational regulation and trafficking of the granulin-containing protease RD21 of Arabidopsis thaliana
Q33927238Potential use of a serpin from Arabidopsis for pest control
Q37943886Probes for activity-based profiling of plant proteases
Q49839079Reassessing apoptosis in plants
Q34232828Serpin protease inhibitors in plant biology
Q38971054Serpin1 and WSCP differentially regulate the activity of the cysteine protease RD21 during plant development in Arabidopsis thaliana
Q24597270Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems
Q34402652Serpins in rice: protein sequence analysis, phylogeny and gene expression during development.
Q34327158Set-point control of RD21 protease activity by AtSerpin1 controls cell death in Arabidopsis
Q89321691Singlet Oxygen Plays an Essential Role in the Root's Response to Osmotic Stress
Q48236707Singlet Oxygen-Induced Membrane Disruption and Serpin-Protease Balance in Vacuolar-Driven Cell Death
Q34174553Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics.
Q46718691Subfamily-Specific Fluorescent Probes for Cysteine Proteases Display Dynamic Protease Activities during Seed Germination.
Q38731573The Increasing Impact of Activity-Based Protein Profiling in Plant Science
Q39674780The SBT6.1 subtilase processes the GOLVEN1 peptide controlling cell elongation.
Q35630328The Tomato yellow leaf curl virus (TYLCV) V2 protein inhibits enzymatic activity of the host papain-like cysteine protease CYP1.
Q50421247The complex world of plant protease inhibitors: Insights into a Kunitz-type cysteine protease inhibitor of Arabidopsis thaliana
Q41873458The tomato yellow leaf curl virus (TYLCV) V2 protein interacts with the host papain-like cysteine protease CYP1.
Q34992418iTRAQ-based quantitative proteome and phosphoprotein characterization reveals the central metabolism changes involved in wheat grain development

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