Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA)

scientific article

Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA) is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1289/EHP.0901827
P3181OpenCitations bibliographic resource ID1494234
P932PMC publication ID2920088
P698PubMed publication ID20423814
P5875ResearchGate publication ID43347978

P50authorDavid A. SavitzQ5230516
Kyle SteenlandQ22089123
P2093author name stringTony Fletcher
P2860cites workImmunotoxicity of perfluorooctanoic acid and perfluorooctane sulfonate and the role of peroxisome proliferator-activated receptor alphaQ23914416
Serum perfluorooctanoic acid and hepatic enzymes, lipoproteins, and cholesterol: A study of occupationally exposed menQ24169422
The relationship between birth weight, gestational age and perfluorooctanoic acid (PFOA)-contaminated public drinking waterQ24623988
Association between serum perfluorooctanoic acid (PFOA) and thyroid disease in the U.S. National Health and Nutrition Examination SurveyQ24624507
Community exposure to perfluorooctanoate: relationships between serum concentrations and exposure sourcesQ24626351
Rate of decline in serum PFOA concentrations after granular activated carbon filtration at two public water systems in Ohio and West VirginiaQ24633826
Exposure to polyfluoroalkyl chemicals and cholesterol, body weight, and insulin resistance in the general U.S. populationQ24633846
Correlations between prenatal exposure to perfluorinated chemicals and reduced fetal growthQ24647791
Prenatal exposure to perfluorooctanoate (PFOA) and perfluorooctanesulfonate (PFOS) and maternally reported developmental milestones in infancyQ24651358
The C8 health project: design, methods, and participantsQ24652791
Do perfluoroalkyl compounds impair human semen quality?Q24657367
Perfluorinated chemicals and fetal growth: a study within the Danish National Birth CohortQ24680484
Cord serum concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in relation to weight and size at birthQ24680500
Polyfluoroalkyl chemicals in the U.S. population: data from the National Health and Nutrition Examination Survey (NHANES) 2003-2004 and comparisons with NHANES 1999-2000Q24680576
Perfluorooctane sulfonate (PFOS) and related perfluorinated compounds in human maternal and cord blood samples: assessment of PFOS exposure in a susceptible population during pregnancy.Q24815415
Central administration of perfluorooctanoic acid inhibits cutaneous inflammationQ28181520
Serum concentrations of 11 polyfluoroalkyl compounds in the u.s. population: data from the national health and nutrition examination survey (NHANES).Q31109567
Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD ratsQ32062110
A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminantsQ33569334
Association of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) with uric acid among adults with elevated community exposure to PFOA.Q33702676
Plasma cholecystokinin and hepatic enzymes, cholesterol and lipoproteins in ammonium perfluorooctanoate production workersQ33924739
Perfluorinated compounds--exposure assessment for the general population in Western countriesQ34012353
Investigation of the associations between low-dose serum perfluorinated chemicals and liver enzymes in US adultsQ34088146
The toxicology of perfluorooctanoateQ34343282
Multiple organic anion transporters contribute to net renal excretion of uric acidQ34470733
Congenital anomalies, labor/delivery complications, maternal risk factors and their relationship with perfluorooctanoic acid (PFOA)-contaminated public drinking waterQ34570340
Community exposure to perfluorooctanoate: relationships between serum levels and certain health parametersQ34571004
Perfluoroalkyl acids: a review of monitoring and toxicological findingsQ34630884
Half-life of serum elimination of perfluorooctanesulfonate,perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workersQ34680365
Serum levels of perfluoroalkyl compounds in human maternal and umbilical cord blood samples.Q34799750
Maternal levels of perfluorinated chemicals and subfecundityQ34931926
Perfluorooctanoate and perfluorooctanesulfonate plasma levels and risk of cancer in the general Danish populationQ34974681
Serum levels of perfluorooctanoic acid and perfluorooctane sulfonate and pregnancy outcomeQ34998270
Association of perfluorooctanoic acid and perfluorooctane sulfonate with serum lipids among adults living near a chemical plant.Q35008916
Perfluorooctanoic acid, perfluorooctanesulfonate, and serum lipids in children and adolescents: results from the C8 Health ProjectQ35049761
PPARalpha agonist-induced rodent tumors: modes of action and human relevanceQ35631058
Perfluorooctanoic acid-induced immunomodulation in adult C57BL/6J or C57BL/6N female miceQ36633073
Biomonitoring of perfluorinated compounds in children and adults exposed to perfluorooctanoate-contaminated drinking waterQ36633077
Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trialQ37197711
Predictors of PFOA levels in a community surrounding a chemical plant.Q37278944
Perfluoroalkyl chemicals and human fetal development: an epidemiologic review with clinical and toxicological perspectivesQ37476192
The association between serum uric acid level and long-term incidence of hypertension: Population-based cohort studyQ39770827
Roles of organic anion transporters in the renal excretion of perfluorooctanoic acid.Q39997446
Guest editorial: biomarkers of perfluorinated chemicals and birth weightQ42714063
A map of European emissions and concentrations of PFOS and PFOA.Q43226207
Maternal exposure to perfluorinated acids and fetal growthQ43253111
Ammonium perfluorooctanoate production and occupational mortalityQ43268281
A cross-sectional analysis of type II diabetes in a community with exposure to perfluorooctanoic acid (PFOA).Q43279026
Estimation and validation of biomarker-based exposures for historical ammonium perfluorooctanoateQ43554786
Toxicity of ammonium perfluorooctanoate in male cynomolgus monkeys after oral dosing for 6 monthsQ44128201
Epidemiologic assessment of worker serum perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) concentrations and medical surveillance examinationsQ44379609
Perfluorooctanesulfonate and related fluorochemicals in human blood from several countriesQ45087717
Ischaemic heart disease mortality study among workers with occupational exposure to ammonium perfluorooctanoate.Q45954303
Exploratory assessment of perfluorinated compounds and human thyroid function.Q46023600
Thirty years of medical surveillance in perfluooctanoic acid production workersQ46118153
Evidence for the involvement of xenobiotic-responsive nuclear receptors in transcriptional effects upon perfluoroalkyl acid exposure in diverse species.Q46151663
Fetal growth indicators and perfluorinated chemicals: a study in the Danish National Birth CohortQ46442964
Evaluation of the immune system in rats and mice administered linear ammonium perfluorooctanoateQ46535824
Retrospective cohort mortality study of workers in a polymer production plant including a reference population of regional workersQ46608357
Perfluorooctane surfactants in waste waters, the major source of river pollution.Q46740568
Cross-sectional study of lipids and liver enzymes related to a serum biomarker of exposure (ammonium perfluorooctanoate or APFO) as part of a general health survey in a cohort of occupationally exposed workersQ46901755
Comparative responses of rats and mice exposed to linear/branched, linear, or branched ammonium perfluorooctanoate (APFO).Q46920851
Preliminary evidence of a decline in perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) concentrations in American Red Cross blood donors.Q50706897
Negative bias from analog methods used in the analysis of free thyroxine in rat serum containing perfluorooctanesulfonate (PFOS).Q51760615
Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action.Q53225736
Serum perfluorooctane sulfonate and hepatic and lipid clinical chemistry tests in fluorochemical production employeesQ73005772
Effects of peroxisome proliferators on the thymus and spleen of miceQ73223344
An epidemiologic investigation of reproductive hormones in men with occupational exposure to perfluorooctanoic acidQ74802865
Assessment of lipid, hepatic, and thyroid parameters with serum perfluorooctanoate (PFOA) concentrations in fluorochemical production workersQ80554158
Longitudinal study of serum lipids and liver enzymes in workers with occupational exposure to ammonium perfluorooctanoateQ80785516
Health risks in infants associated with exposure to perfluorinated compounds in human breast milk from Zhoushan, ChinaQ83829339
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectlipidQ11367
environmental monitoringQ1749732
hydrocarbonQ43648
epidemiologyQ133805
carboxylic acidQ134856
P304page(s)1100-8
P577publication date2010-08-01
P1433published inEnvironmental Health PerspectivesQ1345904
P1476titleEpidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA)
P478volume118

Reverse relations

cites work (P2860)
Q41559585A cohort incidence study of workers exposed to perfluorooctanoic acid (PFOA).
Q93336503A review of the pathways of human exposure to poly- and perfluoroalkyl substances (PFASs) and present understanding of health effects
Q42714327A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid.
Q47234737An integrated approach with the zebrafish model for biomonitoring of municipal wastewater effluent and receiving waters
Q28545810Association between perfluorinated compound exposure and miscarriage in Danish pregnant women
Q50555508Association between perfluorinated compounds and time to pregnancy in a prospective cohort of Danish couples attempting to conceive.
Q28394440Association between perfluoroalkyl acids and kidney function in a cross-sectional study of adolescents
Q55331831Association between perfluoroalkyl substances exposure and thyroid function in adults: A meta-analysis.
Q36618735Association between plasma PFOA and PFOS levels and total cholesterol in a middle-aged Danish population
Q58080051Associations between longitudinal serum perfluoroalkyl substance (PFAS) levels and measures of thyroid hormone, kidney function, and body mass index in the Fernald Community Cohort
Q53105752Associations between perfluoroalkyl compounds and immune and clinical chemistry parameters in highly exposed bottlenose dolphins (Tursiops truncatus).
Q92605021Associations of Perfluoroalkyl substances with blood lipids and Apolipoproteins in lipoprotein subspecies: the POUNDS-lost study
Q99405769Astaxanthin reduces perfluorooctanoic acid cytotoxicity in Saccharomyces cerevisiae
Q38161679Behaviour and fate of perfluoroalkyl and polyfluoroalkyl substances (PFASs) in drinking water treatment: a review
Q33654524Biomarker-based calibration of retrospective exposure predictions of perfluorooctanoic acid.
Q59806739Breast cancer risk and serum levels of per- and poly-fluoroalkyl substances: a case-control study nested in the California Teachers Study
Q28387100Causal inference considerations for endocrine disruptor research in children's health
Q34296310Changing interpretation of human health risks from perfluorinated compounds
Q34307019Cohort mortality study of workers exposed to perfluorooctanoic acid
Q36856193Cross-sectional association between polyfluoroalkyl chemicals and cognitive limitation in the National Health and Nutrition Examination Survey
Q56795452Delayed discovery, dissemination, and decisions on intervention in environmental health: a case study on immunotoxicity of perfluorinated alkylate substances
Q37072630Design, methods, and population for a study of PFOA health effects among highly exposed mid-Ohio valley community residents and workers
Q64278282Dose Effects of Ammonium Perfluorooctanoate on Lipoprotein Metabolism in APOE*3-Leiden.CETP Mice
Q45972435Early life exposure to per- and polyfluoroalkyl substances and mid-childhood lipid and alanine aminotransferase levels.
Q93000711Early pregnancy serum levels of perfluoroalkyl substances and risk of preeclampsia in Swedish women
Q51715142Effect of surfactants on the degradation of perfluorooctanoic acid (PFOA) by ultrasonic (US) treatment.
Q28079540Effects of Environmental Exposures on Fetal and Childhood Growth Trajectories
Q50458119Effects of chronic perfluorooctanoic acid (PFOA) at low concentration on morphometrics, gene expression, and fecundity in zebrafish (Danio rerio).
Q24633469Endocrine disrupting properties of perfluorooctanoic acid
Q26827830Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence
Q47929679Environmental chemicals and preterm birth: Biological mechanisms and the state of the science.
Q37831851Environmental neurotoxicants and developing brain
Q91963302Environmental risk factors for liver cancer and nonalcoholic fatty liver disease
Q30863550Estimating common parameters of lognormally distributed environmental and biomonitoring data: harmonizing disparate statistics from publications
Q60126454Evaluation and Management Strategies for Per- and Polyfluoroalkyl Substances (PFASs) in Drinking Water Aquifers: Perspectives from Impacted U.S. Northeast Communities
Q59217192Exposure to Perfluoroalkyl Substances and Sperm DNA Global Methylation in Arctic and European Populations
Q28383912Exposure to perfluoroalkyl acids and markers of kidney function among children and adolescents living near a chemical plant
Q46319568Exposure to polybrominated diphenyl ethers and perfluoroalkyl substances in a remote population of Alaska Natives.
Q30513661High-performance metabolic profiling of plasma from seven mammalian species for simultaneous environmental chemical surveillance and bioeffect monitoring.
Q28394887Human biological monitoring of suspected endocrine-disrupting compounds
Q63349825Identification of Per- and Polyfluoroalkyl Substances in the Cape Fear River by High Resolution Mass Spectrometry and Nontargeted Screening
Q37959888Immunotoxicity of perfluorinated compounds: recent developments.
Q49935950Impact of perfluorochemicals on human health and reproduction: a male's perspective
Q92633952Increased Cardiovascular Risk Associated with Chemical Sensitivity to Perfluoro-Octanoic Acid: Role of Impaired Platelet Aggregation
Q36840353Influence of salinity and temperature on uptake of perfluorinated carboxylic acids (PFCAs) by hydroponically grown wheat (Triticum aestivum L.).
Q36493907Influenza vaccine response in adults exposed to perfluorooctanoate and perfluorooctanesulfonate
Q36159527Level and temporal trend of perfluoroalkyl acids in Greenlandic Inuit
Q46632573Levels of persistent contaminants in relation to fish consumption among older male anglers in Wisconsin
Q36095017Longitudinal measures of perfluoroalkyl substances (PFAS) in serum of Gullah African Americans in South Carolina: 2003-2013.
Q48377955Low-level perfluorooctanoic acid enhances 3 T3-L1 preadipocyte differentiation via altering peroxisome proliferator activated receptor gamma expression and its promoter DNA methylation.
Q93018646Making the invisible visible: results of a community-led health survey following PFAS contamination of drinking water in Merrimack, New Hampshire
Q28383653Modeled PFOA exposure and coronary artery disease, hypertension, and high cholesterol in community and worker cohorts
Q23915929Mortality and cancer incidence in ammonium perfluorooctanoate production workers
Q28395753No association between perfluoroalkyl chemicals and hypertension in children
Q38989466Obesogens and male fertility.
Q38558478Organ-on-a-chip for assessing environmental toxicants
Q46353579PFCA uptake and translocation in dominant wheat species (Triticum aestivum L.).
Q38068391PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men.
Q89845047Per- and polyfluoroalkyl substances and blood pressure in pre-diabetic adults-cross-sectional and longitudinal analyses of the diabetes prevention program outcomes study
Q47833635Per- and polyfluoroalkyl substances in sera from children 3 to 11 years of age participating in the National Health and Nutrition Examination Survey 2013-2014.
Q38530449Perfluorinated Alkyl Substances: Emerging Insights Into Health Risks.
Q57293921Perfluorinated Chemicals as Emerging Environmental Threats to Kidney Health: A Scoping Review
Q36023451Perfluorinated compounds in relation to birth weight in the Norwegian Mother and Child Cohort Study
Q35631579Perfluorinated compounds: emerging POPs with potential immunotoxicity
Q34275281Perfluoroalkyl chemicals and asthma among children 12-19 years of age: NHANES (1999-2008).
Q24635118Perfluoroalkyl chemicals and elevated serum uric acid in US adults
Q35339240Perfluoroalkyl substances and time to pregnancy in couples from Greenland, Poland and Ukraine
Q28394126Perfluorooctanesulfonate Mediates Renal Tubular Cell Apoptosis through PPARgamma Inactivation
Q52689096Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells.
Q37374188Perfluorooctanoic acid (PFOA) exposures and incident cancers among adults living near a chemical plant
Q42832121Perfluorooctanoic acid binds to peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation in 3T3-L1 adipocytes
Q36261424Perfluorooctanoic acid enhances colorectal cancer DLD-1 cells invasiveness through activating NF-κB mediated matrix metalloproteinase-2/-9 expression
Q34647222Perfluorooctanoic acid exposure and cancer outcomes in a contaminated community: a geographic analysis
Q35874820Perfluorooctanoic acid exposure and pregnancy outcome in a highly exposed community
Q35727717Perfluorooctanoic acid exposure for 28 days affects glucose homeostasis and induces insulin hypersensitivity in mice
Q36185302Perfluorooctanoic acid exposure is associated with elevated homocysteine and hypertension in US adults
Q41681299Perfluorooctanoic acid exposure triggers oxidative stress in the mouse pancreas
Q37687025Perfluorooctanoic acid induces human Ishikawa endometrial cancer cell migration and invasion through activation of ERK/mTOR signaling
Q57213286Physicochemical factors controlling the retention and transport of perfluorooctanoic acid (PFOA) in saturated sand and limestone porous media
Q38690520Physiologically based pharmacokinetic modeling of human exposure to perfluorooctanoic acid suggests historical non drinking-water exposures are important for predicting current serum concentrations
Q49644181Plasma Concentrations of Per- and Polyfluoroalkyl Substances at Baseline and Associations with Glycemic Indicators and Diabetes Incidence among High-Risk Adults in the Diabetes Prevention Program Trial
Q45230914Polybrominated diphenyl ethers and perfluoroalkyl substances in serum of pregnant women: levels, correlations, and potential health implications
Q36876519Positive association between perfluoroalkyl chemicals and hyperuricemia in children
Q42680253Pregnancy-induced hypertension "probably linked" to PFOA contamination
Q77792301Preliminary assessment of exposure to persistent organic pollutants among pregnant women in Puerto Rico
Q36938040Prenatal Exposure to Perfluoroalkyl Substances and Behavioral Development in Children
Q35941792Prenatal exposure to perfluorooctanoate and risk of overweight at 20 years of age: a prospective cohort study
Q52622479Priorities for cancer prevention: lifestyle choices versus unavoidable exposures.
Q34478572Private drinking water wells as a source of exposure to perfluorooctanoic acid (PFOA) in communities surrounding a fluoropolymer production facility
Q28384774Prostate-specific antigen and perfluoroalkyl acids in the C8 health study population
Q37057606Recent developments in methods for analysis of perfluorinated persistent pollutants
Q36493895Reductions in serum lipids with a 4-year decline in serum perfluorooctanoic acid and perfluorooctanesulfonic acid
Q36229096Relationship of perfluorooctanoic acid exposure to pregnancy outcome based on birth records in the mid-Ohio Valley
Q35682907Retrospective exposure estimation and predicted versus observed serum perfluorooctanoic acid concentrations for participants in the C8 Health Project
Q45376606Serum concentrations of perfluorinated alkyl acids and their associations with diet and personal characteristics among Swedish adults
Q36939320Serum perfluoroalkyl acids concentrations and memory impairment in a large cross-sectional study
Q41680536Serum perfluorooctanoic acid (PFOA) concentrations in normal and hyperlipidemic female hamsters dosed orally with ammonium perfluorooctanoate (APFO) for up to 30 days
Q54993802Stochastic Pharmacokinetic-Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA).
Q42705686Structure-activity relations in binding of perfluoroalkyl compounds to human thyroid hormone T3 receptor
Q34275367The Navigation Guide - evidence-based medicine meets environmental health: integration of animal and human evidence for PFOA effects on fetal growth.
Q26851809The Navigation Guide - evidence-based medicine meets environmental health: systematic review of human evidence for PFOA effects on fetal growth
Q34275302The Navigation Guide systematic review methodology: a rigorous and transparent method for translating environmental health science into better health outcomes
Q42924277The Navigation Guide: systematic review for the environmental health sciences
Q46249387The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions.
Q40015587The influence of a non-aqueous phase liquid (NAPL) and chemical oxidant application on perfluoroalkyl acid (PFAA) fate and transport
Q51303543The modifying effect of vitamin C on the association between perfluorinated compounds and insulin resistance in the Korean elderly: a double-blind, randomized, placebo-controlled crossover trial.
Q43955348The role of number of meals, coffee intake, salt and type of cookware on colorectal cancer development in the context of the Mediterranean diet
Q52690564The role of pollutants in type 2 diabetes mellitus (T2DM) and their prospective impact on phytomedicinal treatment strategies.
Q36115374Thyroid function and perfluoroalkyl acids in children living near a chemical plant
Q36602294Toxicological function of adipose tissue: focus on persistent organic pollutants.
Q37072627Ulcerative colitis and perfluorooctanoic acid (PFOA) in a highly exposed population of community residents and workers in the mid-Ohio valley
Q36433117Within- and between-group regression for improving the robustness of causal claims in cross-sectional analysis

Search more.