Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability

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Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1113/JPHYSIOL.2001.013269
P3181OpenCitations bibliographic resource ID3860668
P932PMC publication ID2290209
P698PubMed publication ID11927664
P5875ResearchGate publication ID229638845

P50authorJean CheminQ56951198
Arnaud MonteilQ60869444
Joel NargeotQ67329395
Emmanuel BourinetQ70463387
Philippe LoryQ73308877
P2093author name stringEdward Perez-Reyes
P2860cites workT-type alpha 1H Ca2+ channels are involved in Ca2+ signaling during terminal differentiation (fusion) of human myoblastsQ22254433
Molecular characterization of a neuronal low-voltage-activated T-type calcium channelQ24316054
Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene familyQ24316347
Simulation of the currents involved in rhythmic oscillations in thalamic relay neuronsQ28177403
The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system functionQ28289375
Molecular and functional characterization of a family of rat brain T-type calcium channelsQ28573439
Thalamocortical oscillations in the sleeping and aroused brainQ29619146
Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channelsQ30303630
All thalamocortical neurones possess a T-type Ca2+ 'window' current that enables the expression of bistability-mediated activitiesQ30708479
Low-voltage-activated Ca2+ currents are generated by members of the CavT subunit family (alpha1G/H) in rat primary sensory neurons.Q31993398
Neuronal circuitry of thalamocortical epilepsy and mechanisms of antiabsence drug actionQ33748599
Low voltage activated calcium channels: from genes to functionQ34130456
Structure and functional characterization of a novel human low-voltage activated calcium channelQ34490697
Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons.Q34502373
Ionic currents and spontaneous firing in neurons isolated from the cerebellar nuclei.Q34512528
State-dependent inactivation of the alpha1G T-type calcium channelQ36438939
Intrinsic firing patterns of diverse neocortical neuronsQ36570760
The Us9 gene product of pseudorabies virus, an alphaherpesvirus, is a phosphorylated, tail-anchored type II membrane proteinQ39580271
Alternatively spliced alpha(1G) (Ca(V)3.1) intracellular loops promote specific T-type Ca(2+) channel gating properties.Q40179790
Kinetic modification of the alpha(1I) subunit-mediated T-type Ca(2+) channel by a human neuronal Ca(2+) channel gamma subunit.Q40801607
Overexpression of T-type calcium channels in HEK-293 cells increases intracellular calcium without affecting cellular proliferationQ40865162
Identification of a T-type Ca(2+) channel isoform in murine atrial myocytes (AT-1 cells)Q40889768
Molecular and functional properties of the human alpha(1G) subunit that forms T-type calcium channels.Q40897863
Comparison of the Ca2 + currents induced by expression of three cloned alpha1 subunits, alpha1G, alpha1H and alpha1I, of low-voltage-activated T-type Ca2 + channelsQ40912699
Distinct kinetics of cloned T-type Ca2 + channels lead to differential Ca2 + entry and frequency-dependence during mock action potentialsQ40912707
A T-type calcium channel from mouse brain.Q40965845
Cloning and expression of a novel member of the low voltage-activated T-type calcium channel familyQ40969230
Low-threshold calcium currents in central nervous system neurons.Q41117703
Sleep and arousal: thalamocortical mechanismsQ41369713
The NEURON simulation environmentQ41554850
Properties of a hyperpolarization-activated cation current and its role in rhythmic oscillation in thalamic relay neuronesQ43450968
A novel T-type current underlies prolonged Ca(2+)-dependent burst firing in GABAergic neurons of rat thalamic reticular nucleusQ43510089
Subtypes of low voltage-activated Ca2+ channels in laterodorsal thalamic neurons: possible localization and physiological rolesQ43584529
Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channelsQ43702724
Action potential waveform voltage-clamp commands reveal striking differences in calcium entry via low and high voltage activated calcium channelsQ44449497
Morphological and physiological differentiation of Purkinje neurons in cultures of rat cerebellumQ45065586
In vivo, in vitro, and computational analysis of dendritic calcium currents in thalamic reticular neuronsQ46074244
Ionic basis for the electro-responsiveness and oscillatory properties of guinea-pig thalamic neurones in vitro.Q46818160
Specific properties of T-type calcium channels generated by the human alpha 1I subunit.Q47872006
Properties of sodium currents and action potential firing in isolated cerebellar Purkinje neuronsQ48157988
A model of the electrophysiological properties of thalamocortical relay neuronsQ48428555
Dendritic low-threshold calcium currents in thalamic relay cells.Q48455921
Two distinct populations of calcium channels in a clonal line of pituitary cells.Q48536898
The 'window' component of the low threshold Ca2+ current produces input signal amplification and bistability in cat and rat thalamocortical neurones.Q48545120
Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons.Q48683657
Electrophysiology of mammalian thalamic neurones in vitro.Q48933746
Electrophysiological properties of cat reticular thalamic neurones in vivo.Q51653483
Three types of neuronal calcium channel with different calcium agonist sensitivity.Q51824457
Multiple Ca2+ currents elicited by action potential waveforms in acutely isolated adult rat dorsal root ganglion neuronsQ54270769
A low voltage-activated, fully inactivating Ca channel in vertebrate sensory neuronesQ59075458
Selective increase in T-type calcium conductance of reticular thalamic neurons in a rat model of absence epilepsyQ72170085
P433issuePt 1
P407language of work or nameEnglishQ1860
P304page(s)3-14
P577publication date2002-04-01
P1433published inJournal of PhysiologyQ7743612
P1476titleSpecific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability
P478volume540

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cites work (P2860)
Q3741453417Beta-estradiol regulation of T-type calcium channels in gonadotropin-releasing hormone neurons
Q3660908317β-oestradiol regulation of gonadotrophin-releasing hormone neuronal excitability
Q28115409A Recurrent Mutation in CACNA1G Alters Cav3.1 T-Type Calcium-Channel Conduction and Causes Autosomal-Dominant Cerebellar Ataxia
Q91012466A novel phospho-modulatory mechanism contributes to the calcium-dependent regulation of T-type Ca2+ channels
Q81527095A-type and T-type currents interact to produce a novel spike latency-voltage relationship in cerebellar stellate cells
Q39008538Activity-dependent regulation of T-type calcium channels by submembrane calcium ions
Q30309951Alternative splicing of the rat Ca(v)3.3 T-type calcium channel gene produces variants with distinct functional properties(1).
Q37367620An acquired channelopathy involving thalamic T-type Ca2+ channels after status epilepticus
Q30541205Analgesic effect of a mixed T-type channel inhibitor/CB2 receptor agonist
Q44557615Apamin-sensitive small conductance calcium-activated potassium channels, through their selective coupling to voltage-gated calcium channels, are critical determinants of the precision, pace, and pattern of action potential generation in rat subthala
Q35610757Availability of low-threshold Ca2+ current in retinal ganglion cells
Q28392275Biology of Parkinson's disease: pathogenesis and pathophysiology of a multisystem neurodegenerative disorder
Q34504333Bursting of thalamic neurons and states of vigilance
Q36356920Ca-α1T, a fly T-type Ca2+ channel, negatively modulates sleep.
Q54096782CaV 3.2 drives sustained burst-firing, which is critical for absence seizure propagation in reticular thalamic neurons.
Q35543117CaV1.2/CaV3.x channels mediate divergent vasomotor responses in human cerebral arteries
Q30440317CaV3.2 is the major molecular substrate for redox regulation of T-type Ca2+ channels in the rat and mouse thalamus
Q34851356Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice
Q45069125Calmodulin regulates Cav3 T-type channels at their gating brake.
Q24307585Caveolin-3 regulates protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channels
Q58606217Cell-Type Specific Distribution of T-Type Calcium Currents in Lamina II Neurons of the Rat Spinal Cord
Q60713082Characterisation of rebound depolarisation in mice deep dorsal horn neurons in vitro
Q40205455Chemical determinants involved in anandamide-induced inhibition of T-type calcium channels.
Q30435619Contrasting anesthetic sensitivities of T-type Ca2+ channels of reticular thalamic neurons and recombinant Ca(v)3.3 channels
Q37817635Contributions of T-type calcium channel isoforms to neuronal firing
Q55271738Cytosolic ATP Relieves Voltage-Dependent Inactivation of T-Type Calcium Channels and Facilitates Excitability of Neurons in the Rat Central Medial Thalamus.
Q35543658Dendritic low-threshold Ca 2+ channels in rat cerebellar Purkinje cells: possible physiological implications
Q45105872Dendritic sodium spikelets and low-threshold calcium spikes in turtle olfactory bulb granule cells
Q35341725Diabetic neuropathy enhances voltage-activated Ca2+ channel activity and its control by M4 muscarinic receptors in primary sensory neurons
Q36107220Elimination of the actin-binding domain in kelch-like 1 protein induces T-type calcium channel modulation only in the presence of action potential waveforms
Q46703446Enhancement of excitatory synaptic integration by GABAergic inhibition in the subthalamic nucleus.
Q28578780Enhancement of low-voltage-activated calcium currents by group II metabotropic glutamate receptors in rat retinal ganglion cells
Q46939214Estrogen upregulates T-type calcium channels in the hypothalamus and pituitary.
Q41849996Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.
Q92373855Exploring the molecular basis of neuronal excitability in a vocal learner
Q42430363Expression of CaV3.2 T-type Ca²⁺ channels in a subpopulation of retinal type-3 cone bipolar cells
Q40261309Focal cortical infarcts alter intrinsic excitability and synaptic excitation in the reticular thalamic nucleus
Q30437932Forward suppression in the auditory cortex is caused by the Ca(v)3.1 calcium channel-mediated switch from bursting to tonic firing at thalamocortical projections
Q28250190Functional characterization and neuronal modeling of the effects of childhood absence epilepsy variants of CACNA1H, a T-type calcium channel
Q28543233Functional expression of T-type Ca2+ channels in spinal motoneurons of the adult turtle
Q30433971Functional impact of alternative splicing of human T-type Cav3.3 calcium channels
Q35157838Functional roles of cytoplasmic loops and pore lining transmembrane helices in the voltage-dependent inactivation of HVA calcium channels.
Q47705054GABAB receptors suppress burst-firing in reticular thalamic neurons
Q28239380Gating effects of mutations in the Cav3.2 T-type calcium channel associated with childhood absence epilepsy
Q28728383Gene transcription and splicing of T-type channels are evolutionarily-conserved strategies for regulating channel expression and gating
Q28477505Hippocampal CA3 transcriptome signature correlates with initial precipitating injury in refractory mesial temporal lobe epilepsy
Q30441251I-II loop structural determinants in the gating and surface expression of low voltage-activated calcium channels
Q35144326Imaging of thalamocortical dysrhythmia in neuropsychiatry.
Q38880329Inhibition of Cav3.2 T-type Calcium Channels by Its Intracellular I-II Loop.
Q48164908Ionic Mechanisms of Burst Firing in Dissociated Purkinje Neurons
Q36571503Ionic mechanisms of endogenous bursting in CA3 hippocampal pyramidal neurons: a model study
Q35696157Kisspeptin and Gonadotropin-Releasing Hormone Neuronal Excitability: Molecular Mechanisms Driven by 17β-Estradiol
Q38120050Low threshold T-type calcium channels as targets for novel epilepsy treatments.
Q35682302Low-voltage-activated ("T-Type") calcium channels in review
Q99557347Modified parylene-N films as chemical microenvironments for differentiation and spheroid formation of osteoblast cells
Q35682306Modulation and pharmacology of low voltage-activated ("T-Type") calcium channels
Q44921188Modulation of T-type Ca2+ channels by Lavender and Rosemary extracts.
Q36956889Molecular identity and functional properties of a novel T-type Ca2+ channel cloned from the sensory epithelia of the mouse inner ear
Q35543999Multiple T-type Ca2+ current subtypes in electrophysiologically characterized hamster dorsal horn neurons: possible role in spinal sensory integration
Q37218136Numb-mediated neurite outgrowth is isoform-dependent, and requires activation of voltage-dependent calcium channels
Q41121791Ontogenic Changes and Differential Localization of T-type Ca(2+) Channel Subunits Cav3.1 and Cav3.2 in Mouse Hippocampus and Cerebellum
Q36268559Phosphorylation of the Cav3.2 T-type calcium channel directly regulates its gating properties
Q44578387Preservation of motor neuron Ca2+ channel sensitivity to insulin-like growth factor-1 in brain motor cortex from senescent rat.
Q42467261Presynaptic T-type Ca2+ channels modulate dendrodendritic mitral-mitral and mitral-periglomerular connections in mouse olfactory bulb.
Q48945328Rebound excitation triggered by synaptic inhibition in cerebellar nuclear neurons is suppressed by selective T-type calcium channel block.
Q34354233Regulation of endogenous conductances in GnRH neurons by estrogens
Q44516289Regulation of granule cell excitability by a low-threshold calcium spike in turtle olfactory bulb
Q44589954Reversal of experimental neuropathic pain by T-type calcium channel blockers
Q35104288Role for T-type Ca2+ channels in sleep waves
Q33661077Role of antispasmodics in the treatment of irritable bowel syndrome
Q40126566Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors.
Q26850970Signal processing by T-type calcium channel interactions in the cerebellum
Q40949695Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception.
Q37487752Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network
Q30433407Structural determinants of the high affinity extracellular zinc binding site on Cav3.2 T-type calcium channels
Q58044559Subcellular distribution of α1G subunit of T-type calcium channel in the mouse dorsal lateral geniculate nucleus
Q47953391Subthalamic discharges as a causal determinant of parkinsonian motor deficits
Q40212704Subunit-specific modulation of T-type calcium channels by zinc.
Q38187360T-type Ca2+ channels in absence epilepsy
Q38125277T-type Ca2+ channels in normal and abnormal brain functions
Q28241278T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome
Q38960816T-type calcium channels in synaptic plasticity
Q39741088T-type current modulation by the actin-binding protein Kelch-like 1.
Q40081052Temperature-dependent modulation of CaV3 T-type calcium channels by protein kinases C and A in mammalian cells.
Q38686593The Role of Calcium Channels in Epilepsy
Q40408433The involvement of Cav3.2/alpha1H T-type calcium channels in excitability of mouse embryonic primary vestibular neurones.
Q38138513The many faces of T-type calcium channels
Q47954497Tonotopic Variation of the T-Type Ca2+ Current in Avian Auditory Coincidence Detector Neurons
Q42126309Transcriptional Profiling of Cutaneous MRGPRD Free Nerve Endings and C-LTMRs
Q39376541Transcriptional regulation of T-type calcium channel CaV3.2: bi-directionality by early growth response 1 (Egr1) and repressor element 1 (RE-1) protein-silencing transcription factor (REST).
Q34295379Transcriptional regulation of α1H T-type calcium channel under hypoxia
Q33748128Transient and big are key features of an invertebrate T-type channel (LCav3) from the central nervous system of Lymnaea stagnalis
Q36525559Voltage-gated calcium channels and idiopathic generalized epilepsies.
Q80371292[Genetic diversity of voltage-gated calcium channels]
Q36605423mRNA expression of ion channels in GnRH neurons: subtype-specific regulation by 17β-estradiol

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