| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Paola Pizzo | Q58873319 |
| Fulvio Celsi | Q54449613 | ||
| Carmen Fotino | Q57528501 | ||
| Paolo Pinton | Q37374908 | ||
| Marisa Brini | Q39956417 | ||
| Rosario Rizzuto | Q41312267 | ||
| P2093 | author name string | Sara Leo | |
| P2860 | cites work | Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity | Q22254785 |
| Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations | Q24301868 | ||
| Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1 | Q24302464 | ||
| Recombinant expression of the Ca(2+)-sensitive aspartate/glutamate carrier increases mitochondrial ATP production in agonist-stimulated Chinese hamster ovary cells | Q24307541 | ||
| Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1 | Q24310249 | ||
| Parkin is recruited selectively to impaired mitochondria and promotes their autophagy | Q24317471 | ||
| Localization of LRRK2 to membranous and vesicular structures in mammalian brain | Q24318643 | ||
| PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons | Q24322788 | ||
| Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death | Q28242641 | ||
| Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases | Q28269333 | ||
| Normal huntingtin function: an alternative approach to Huntington's disease | Q28281904 | ||
| Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria | Q28285347 | ||
| The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action | Q28366131 | ||
| DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase | Q28513159 | ||
| Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia | Q28585666 | ||
| Mitochondrial dysfunction and oxidative damage in parkin-deficient mice | Q28593859 | ||
| Innovation: Looking forward to seeing calcium | Q29040650 | ||
| Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin | Q29615684 | ||
| Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin | Q29617063 | ||
| The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila | Q29617091 | ||
| Kinetics of mitochondrial calcium transport. II. A kinetic description of the sodium-dependent calcium efflux mechanism of liver mitochondria and inhibition by ruthenium red and by tetraphenylphosphonium | Q68976622 | ||
| Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons | Q73675821 | ||
| Control of InsP3-induced Ca2+ oscillations in permeabilized blowfly salivary gland cells: contribution of mitochondria | Q73900892 | ||
| VOLUME CHANGES INDUCED BY INORGANIC PHOSPHATE IN LIVER MITOCHONDRIA | Q78542414 | ||
| Are mitochondria critical in the pathogenesis of Alzheimer's disease? | Q81440649 | ||
| Up-regulation of inositol 1,4,5-trisphosphate receptor type 1 is responsible for a decreased endoplasmic-reticulum Ca2+ content in presenilin double knock-out cells | Q83288026 | ||
| Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration | Q45302924 | ||
| Increased caspase-2, calpain activations and decreased mitochondrial complex II activity in cells expressing exogenous huntingtin exon 1 containing CAG repeat in the pathogenic range | Q45306567 | ||
| PS2 mutation increases neuronal cell vulnerability to neurotoxicants through activation of caspase-3 by enhancing of ryanodine receptor-mediated calcium release | Q46880293 | ||
| Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease | Q48920532 | ||
| Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42. | Q49134222 | ||
| Chronic exposure to sub-lethal beta-amyloid (Abeta) inhibits the import of nuclear-encoded proteins to mitochondria in differentiated PC12 cells. | Q50665343 | ||
| Different species of alpha-synuclein oligomers induce calcium influx and seeding. | Q52581429 | ||
| Cytochrome oxidase deficiency in Alzheimer's disease. | Q53181028 | ||
| Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide. | Q53216314 | ||
| Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels. | Q53277217 | ||
| A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients. | Q53341470 | ||
| Presenilins and Alzheimer disease: the calcium conspiracy. | Q53382538 | ||
| Beta-amyloid precursor protein is a direct cleavage target of HtrA2 serine protease. Implications for the physiological function of HtrA2 in the mitochondria. | Q53588924 | ||
| Regulation of Ca2+ Efflux in Rat Liver Mitochondria. Role of Membrane Potential | Q58454407 | ||
| Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators | Q29617353 | ||
| Amyloid precursor protein trafficking, processing, and function | Q29617429 | ||
| BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis | Q29620466 | ||
| Impact of mitochondrial Ca2+ cycling on pattern formation and stability | Q30447507 | ||
| Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. | Q30477849 | ||
| SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production | Q30482542 | ||
| N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking | Q30486372 | ||
| Evidence that mitochondria buffer physiological Ca2+ loads in lizard motor nerve terminals | Q32067534 | ||
| Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate | Q34054189 | ||
| Imaging the permeability pore transition in single mitochondria | Q34167671 | ||
| Complex I and Parkinson's disease | Q34499041 | ||
| Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses | Q34831241 | ||
| Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease | Q34988301 | ||
| Historical review: mitochondria and calcium: ups and downs of an unusual relationship | Q35114277 | ||
| Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation | Q35757239 | ||
| Deranged neuronal calcium signaling and Huntington disease. | Q35874324 | ||
| Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. | Q36119444 | ||
| Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals | Q36241923 | ||
| Mitochondrial participation in the intracellular Ca2+ network | Q36254615 | ||
| 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease. | Q36318579 | ||
| Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells | Q36323368 | ||
| Microdomains of intracellular Ca2+: molecular determinants and functional consequences. | Q36350079 | ||
| Optical probing of neuronal circuit dynamics: genetically encoded versus classical fluorescent sensors. | Q36380371 | ||
| Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1alpha and oxidative phosphorylation | Q36534424 | ||
| Mitochondrial alterations in Alzheimer's disease | Q36549402 | ||
| Parkin and defective ubiquitination in Parkinson's disease | Q36611521 | ||
| Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming | Q36702104 | ||
| Calcium and neurodegeneration | Q36747495 | ||
| Biosensors for the detection of calcium and pH. | Q36796229 | ||
| Targeting aequorin and green fluorescent protein to intracellular organelles | Q36807899 | ||
| Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease | Q36820873 | ||
| The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology | Q37031106 | ||
| Mitochondria in the aetiology and pathogenesis of Parkinson's disease | Q37037953 | ||
| Mitochondrial Ca2+ and the heart | Q37051821 | ||
| Mitochondrial dynamics: to be in good shape to survive | Q37108458 | ||
| VDAC regulation: role of cytosolic proteins and mitochondrial lipids | Q37163358 | ||
| Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease | Q37463481 | ||
| Ca2+ as a second messenger within mitochondria of the heart and other tissues | Q37918891 | ||
| Kinetics of calcium(2+) ion carrier in rat liver mitochondria | Q39291877 | ||
| Mitochondria exert a negative feedback on the propagation of intracellular Ca2+ waves in rat cortical astrocytes | Q39508107 | ||
| Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux | Q39891449 | ||
| Interplay of the Ca2+-binding protein DREAM with presenilin in neuronal Ca2+ signaling | Q39956189 | ||
| Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease | Q40031554 | ||
| Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence | Q40137371 | ||
| Apoptotic mechanisms in mutant LRRK2-mediated cell death | Q40149547 | ||
| Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression | Q40301497 | ||
| Reduction of Ca2+ stores and capacitative Ca2+ entry is associated with the familial Alzheimer's disease presenilin-2 T122R mutation and anticipates the onset of dementia. | Q40449011 | ||
| Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis | Q40545020 | ||
| Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release | Q40551652 | ||
| The presenilin 2 M239I mutation associated with familial Alzheimer's disease reduces Ca2+ release from intracellular stores | Q40581064 | ||
| Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. | Q40721588 | ||
| Modulation of intramitochondrial free Ca2+ concentration by antagonists of Na(+)-Ca2+ exchange | Q40808697 | ||
| A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency | Q40938846 | ||
| New light on mitochondrial calcium | Q40978945 | ||
| Ca2+ homeostasis in the agonist-sensitive internal store: functional interactions between mitochondria and the ER measured In situ in intact cells. | Q41010150 | ||
| Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating. | Q41256595 | ||
| The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal | Q41456661 | ||
| Presenilin-2 mutations modulate amplitude and kinetics of inositol 1, 4,5-trisphosphate-mediated calcium signals | Q41700856 | ||
| Apoptosis driven by IP(3)-linked mitochondrial calcium signals | Q42265765 | ||
| Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis | Q42467635 | ||
| Active mitochondria surrounding the pancreatic acinar granule region prevent spreading of inositol trisphosphate-evoked local cytosolic Ca(2+) signals. | Q42477596 | ||
| Calcium ion-dependent signalling and mitochondrial dysfunction: mitochondrial calcium uptake during hormonal stimulation in intact liver cells and its implication for the mitochondrial permeability transition | Q42479987 | ||
| Integrating cytosolic calcium signals into mitochondrial metabolic responses | Q42652819 | ||
| Oxidative damage is the earliest event in Alzheimer disease | Q43696731 | ||
| Beta-amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons | Q44149266 | ||
| The mitochondrial calcium uniporter is a highly selective ion channel. | Q44737530 | ||
| Inhibition of mitochondrial Na+-Ca2+ exchange restores agonist-induced ATP production and Ca2+ handling in human complex I deficiency. | Q44989706 | ||
| Bcl-2 and Bax exert opposing effects on Ca2+ signaling, which do not depend on their putative pore-forming region | Q45107840 | ||
| Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity | Q45244063 | ||
| Huntingtin localization in brains of normal and Huntington's disease patients | Q45295341 | ||
| Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin | Q45297269 | ||
| Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. | Q45302702 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| biophysics | Q7100 | ||
| neurodegeneration | Q1755122 | ||
| cell death | Q2383867 | ||
| mitochondrion | Q39572 | ||
| P304 | page(s) | 335-44 | |
| P577 | publication date | 2009-05-01 | |
| P1433 | published in | Biochimica et Biophysica Acta | Q864239 |
| P1476 | title | Mitochondria, calcium and cell death: a deadly triad in neurodegeneration | |
| P478 | volume | 1787 |
| Q38436152 | A Survey of Marine Natural Compounds and Their Derivatives with Anti-cancer Activity Reported in 2012. |
| Q37774749 | A neurological perspective on mitochondrial disease. |
| Q34073879 | A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease |
| Q35232631 | A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug. |
| Q35245867 | Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons |
| Q34990005 | Alterations in energy metabolism, neuroprotection and visual signal transduction in the retina of Parkinsonian, MPTP-treated monkeys |
| Q61809658 | Alzheimer's Disease Presenilin-1 Mutation Sensitizes Neurons to Impaired Autophagy Flux and Propofol Neurotoxicity: Role of Calcium Dysregulation |
| Q34007444 | Alzheimer's disease: diverse aspects of mitochondrial malfunctioning |
| Q38994461 | Amyloid-beta disrupts calcium and redox homeostasis in brain endothelial cells |
| Q33812214 | Analysis of the mitochondrial proteome in multiple sclerosis cortex |
| Q40541548 | Antioxidant-Rich Fraction of Urtica dioica Mediated Rescue of Striatal Mito-Oxidative Damage in MPTP-Induced Behavioral, Cellular, and Neurochemical Alterations in Rats |
| Q37673274 | Basic mechanisms of neurodegeneration: a critical update |
| Q39652736 | Calcium Flux between the Endoplasmic Reticulum and Mitochondrion Contributes to Poliovirus-Induced Apoptosis |
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| Q37771025 | Calcium dysregulation and homeostasis of neural calcium in the molecular mechanisms of neurodegenerative diseases provide multiple targets for neuroprotection |
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| Q92401022 | Calcium-induced transformation of cardiolipin nanodisks |
| Q59844917 | Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity |
| Q53751609 | Circulating microRNAs as biomarkers in progressive multiple sclerosis. |
| Q39239859 | Computational analysis of Ca2+ dynamics in isolated cardiac mitochondria predicts two distinct modes of Ca2+ uptake |
| Q36094313 | Critical role for calcium mobilization in activation of the NLRP3 inflammasome |
| Q41959197 | Cytosolic calcium measurements in renal epithelial cells by flow cytometry |
| Q27307877 | Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease |
| Q64094615 | Developmental Axon Degeneration Requires TRPV1-Dependent Ca Influx |
| Q99353141 | Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis |
| Q38116463 | Do we age because we have mitochondria? |
| Q47980482 | Early stress evokes temporally distinct consequences on the hippocampal transcriptome, anxiety and cognitive behaviour. |
| Q44147847 | Effect of β-amyloid (25-35) on mitochondrial function and expression of mitochondrial permeability transition pore proteins in rat hippocampal neurons |
| Q63245460 | Evaluation of the Antioxidant and Neuroprotectant Activities of New Asymmetrical 1,3-Diketones |
| Q39384617 | Evidence of Mitochondrial Dysfunction in Autism: Biochemical Links, Genetic-Based Associations, and Non-Energy-Related Mechanisms. |
| Q95840757 | Evidence of a Role for the TRPC Subfamily in Mediating Oxidative Stress in Parkinson's Disease |
| Q36223940 | Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration |
| Q36078713 | Expression of a truncated form of the endoplasmic reticulum chaperone protein, σ1 receptor, promotes mitochondrial energy depletion and apoptosis. |
| Q36745208 | Glutamate transporters in brain ischemia: to modulate or not? |
| Q38077216 | Glutathione and γ-glutamylcysteine in the antioxidant and survival functions of mitochondria. |
| Q26767233 | How Shigella Utilizes Ca(2+) Jagged Edge Signals during Invasion of Epithelial Cells |
| Q35569964 | How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario |
| Q37855570 | IP(3) Receptors, Mitochondria, and Ca Signaling: Implications for Aging |
| Q36318758 | Identification of an N-methyl-D-aspartate receptor in isolated nervous system mitochondria |
| Q35044366 | Identifying Aβ-specific pathogenic mechanisms using a nematode model of Alzheimer's disease |
| Q62036053 | Inherited Neuropathies |
| Q27313143 | Inhibiting cholesterol degradation induces neuronal sclerosis and epileptic activity in mouse hippocampus. |
| Q37636324 | Intracellular calcium signalling in Alzheimer's disease |
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| Q64102520 | Mechanisms Through Which Some Mitochondria-Generated Metabolites Act as Second Messengers That Are Essential Contributors to the Aging Process in Eukaryotes Across Phyla |
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| Q38970493 | Proteasome dysfunction in cardiomyopathies. |
| Q39639654 | Proteomic analysis of dopamine and α-synuclein interplay in a cellular model of Parkinson's disease pathogenesis |
| Q46780257 | Purinergic signalling mobilizes mitochondrial Ca²⁺ in mouse Sertoli cells |
| Q34999535 | Recent advances in our understanding of neurodegeneration |
| Q36472468 | Reduced mitochondrial Ca(2+) transients stimulate autophagy in human fibroblasts carrying the 13514A>G mutation of the ND5 subunit of NADH dehydrogenase. |
| Q58716523 | Reduction of PINK1 or DJ-1 impair mitochondrial motility in neurites and alter ER-mitochondria contacts |
| Q37836981 | Review: The role of mitochondria in the pathogenesis of amyotrophic lateral sclerosis. |
| Q48846537 | Role of nuclear receptor on regulation of BDNF and neuroinflammation in hippocampus of β-amyloid animal model of Alzheimer's disease |
| Q42516901 | Role of serum albumin as a nanoparticulate carrier for nose-to-brain delivery of R-flurbiprofen: implications for the treatment of Alzheimer's disease. |
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| Q35814018 | Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells. |
| Q35988679 | Targeting of short TRPM8 isoforms induces 4TM-TRPM8-dependent apoptosis in prostate cancer cells. |
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