scholarly article | Q13442814 |
P356 | DOI | 10.1128/MCB.17.3.1224 |
P8608 | Fatcat ID | release_kuvkaa7cwvdbjm4w5waopeq4mu |
P932 | PMC publication ID | 231847 |
P698 | PubMed publication ID | 9032249 |
P5875 | ResearchGate publication ID | 14178638 |
P2093 | author name string | T Takano | |
M Oshimura | |||
J Mashimo | |||
K Nose | |||
M Shibanuma | |||
S Imai | |||
E Mochizuki | |||
N Nishiya | |||
R Maniwa | |||
P2860 | cites work | Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL | Q24306777 |
Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation | Q24306857 | ||
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Q24319848 | ||
Characterization of the TGF beta 1-inducible hic-5 gene that encodes a putative novel zinc finger protein and its possible involvement in cellular senescence | Q24323214 | ||
Chromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1 | Q24629799 | ||
A new technique for the assay of infectivity of human adenovirus 5 DNA | Q27860797 | ||
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins | Q27861094 | ||
Existence of high abundance antiproliferative mRNA's in senescent human diploid fibroblasts | Q46687908 | ||
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen | Q48084448 | ||
1.5 kb mRNA abundantly expressed in rat tumors encodes a 37 kilodalton protein in vitro | Q48375291 | ||
Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma. | Q50586207 | ||
Neoplastic transformation of human diploid fibroblasts (KMST-6) by treatment with 60Co gamma rays | Q52832421 | ||
Multistep carcinogenesis of normal human fibroblasts. Human fibroblasts immortalized by repeated treatment with Co-60 gamma rays were transformed into tumorigenic cells with Ha-ras oncogenes | Q53520574 | ||
Copy number of a human type I alpha 2 collagen gene | Q67235562 | ||
Telomere positional effects and the regulation of cellular senescence | Q68007322 | ||
Contact-inhibition-induced quiescent state is marked by intense nuclear expression of statin | Q68195923 | ||
Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport | Q70170049 | ||
Evidence for the recessive nature of cellular immortality | Q71810575 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS | Q28202269 | ||
p21 is a universal inhibitor of cyclin kinases | Q28257305 | ||
The growth arrest-specific gene, gas1, is involved in growth suppression | Q28587372 | ||
The serial cultivation of human diploid cell strains | Q29547356 | ||
pEF-BOS, a powerful mammalian expression vector | Q29547606 | ||
E2F: a link between the Rb tumor suppressor protein and viral oncoproteins | Q29618375 | ||
Genetic analysis of indefinite division in human cells: identification of four complementation groups | Q33640611 | ||
The LIM domain is a modular protein-binding interface | Q34325141 | ||
Identification of a highly abundant cDNA isolated from senescent WI-38 cells | Q35165114 | ||
Human fibronectin: cell specific alternative mRNA splicing generates polypeptide chains differing in the number of internal repeats. | Q35433852 | ||
Senescence of immortal human fibroblasts by the introduction of normal human chromosome 6 | Q35472884 | ||
Expression of cell cycle-dependent genes in young and senescent WI-38 fibroblasts | Q35605301 | ||
Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation | Q35614668 | ||
Cloning and sequence of a cDNA coding for the human beta-migrating endothelial-cell-type plasminogen activator inhibitor | Q36430764 | ||
A gene involved in control of human cellular senescence on human chromosome 1q | Q36649408 | ||
Loss of serum response element-binding activity and hyperphosphorylation of serum response factor during cellular aging | Q36658009 | ||
Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes | Q36686434 | ||
Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence | Q36727404 | ||
The LIM domain: a new structural motif found in zinc-finger-like proteins. | Q36728285 | ||
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents | Q36761728 | ||
Growth of immortal simian virus 40 tsA-transformed human fibroblasts is temperature dependent | Q36770140 | ||
Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells | Q36834831 | ||
Induction of metallothionein and other mRNA species by carcinogens and tumor promoters in primary human skin fibroblasts | Q36914342 | ||
Prohibitin, an evolutionarily conserved intracellular protein that blocks DNA synthesis in normal fibroblasts and HeLa cells | Q36958660 | ||
Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4. | Q37540466 | ||
Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation | Q37639646 | ||
Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene | Q37684502 | ||
Replicative senescence: the human fibroblast comes of age. | Q37951214 | ||
Molecular Genetic Approaches to the Study of Cellular Senescence | Q40431282 | ||
Molecular and Cell Biology of Replicative Senescence | Q40431309 | ||
Why are human cells resistant to malignant cell transformation in vitro? | Q40798787 | ||
Replicative senescence of human skin fibroblasts correlates with a loss of regulation and overexpression of collagenase activity | Q41272633 | ||
Evidence for multiple pathways to cellular senescence. | Q41418473 | ||
Immortalization-susceptible elements and their binding factors mediate rejuvenation of regulation of the type I collagenase gene in simian virus 40 large T antigen-transformed immortal human fibroblasts | Q41431649 | ||
Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1. | Q41668628 | ||
Changes in fibronectin mRNA splicing with in vitro passage | Q41673671 | ||
Fibronectin expression increases during in vitro cellular senescence: correlation with increased cell area | Q41675923 | ||
Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts | Q41725165 | ||
Induction of cellular senescence in immortalized cells by human chromosome 1. | Q41744236 | ||
Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts | Q41748100 | ||
The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors | Q43965576 | ||
Regulation of two E2F-related genes in presenescent and senescent human fibroblasts | Q44141795 | ||
Regulation of collagenase and collagenase mRNA production in early- and late-passage human diploid fibroblasts | Q44234904 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1224-35 | |
P577 | publication date | 1997-03-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Induction of senescence-like phenotypes by forced expression of hic-5, which encodes a novel LIM motif protein, in immortalized human fibroblasts | |
P478 | volume | 17 |
Q40593654 | A LIM protein, Hic-5, functions as a potential coactivator for Sp1. |
Q38770999 | Aging up-regulates ARA55 in stromal cells, inducing androgen-mediated prostate cancer cell proliferation and migration |
Q34620003 | Bilateral administration of autologous CD133+ cells in ambulatory patients with refractory critical limb ischemia: lessons learned from a pilot randomized, double-blind, placebo-controlled trial |
Q22010953 | Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses |
Q37763785 | Bypassing cellular senescence by genetic screening tools |
Q34474505 | Cbl-c Ubiquitin Ligase Activity Is Increased via the Interaction of Its RING Finger Domain with a LIM Domain of the Paxillin Homolog, Hic 5 |
Q24318621 | Cell Adhesion Kinase β Forms a Complex with a New Member, Hic-5, of Proteins Localized at Focal Adhesions |
Q37828383 | Cellular senescence as a target in cancer control |
Q22009024 | Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate |
Q34146411 | Clusterin/apolipoprotein J in human aging and cancer |
Q77346198 | Clusterin/apolipoprotein J is a novel biomarker of cellular senescence that does not affect the proliferative capacity of human diploid fibroblasts |
Q37246647 | Critical pathways in cellular senescence and immortalization revealed by gene expression profiling. |
Q44947582 | Distinct LIM domains of Hic-5/ARA55 are required for nuclear matrix targeting and glucocorticoid receptor binding and coactivation |
Q42468045 | Downregulation of metallothionein-IIA expression occurs at immortalization |
Q47763114 | Expression of AR associated protein 55 (ARA55) and androgen receptor in prostate cancer |
Q34200801 | Expression of androgen receptor coactivators in normal and cancer prostate tissues and cultured cell lines |
Q41041005 | Forced expression of hic-5, a senescence-related gene, potentiates a differentiation process of RCT-1 cells induced by retinoic acid |
Q47857299 | Genomic structure and chromosomal mapping of the mouse hic-5 gene that encodes a focal adhesion protein |
Q39489450 | HIC-5: A Mobile Molecular Scaffold Regulating the Anchorage Dependence of Cell Growth |
Q36008830 | Hic-5 Regulates Actin Cytoskeletal Reorganization and Expression of Fibrogenic Markers and Myocilin in Trabecular Meshwork Cells |
Q39739902 | Hic-5 communicates between focal adhesions and the nucleus through oxidant-sensitive nuclear export signal |
Q35923246 | Hic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8 |
Q35925292 | Hic-5 promotes invadopodia formation and invasion during TGF-β-induced epithelial-mesenchymal transition. |
Q41143061 | Hic-5 promotes the hypertrophic scar myofibroblast phenotype by regulating the TGF-beta1 autocrine loop. |
Q28139714 | Hic-5, a paxillin homologue, binds to the protein-tyrosine phosphatase PEST (PTP-PEST) through its LIM 3 domain |
Q24550885 | Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase |
Q33930334 | In vitro aging research in Japan |
Q28139276 | Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST |
Q22003881 | Interaction of Hic-5, A Senescence-related Protein, with Focal Adhesion Kinase |
Q24549599 | Interaction of the tau2 transcriptional activation domain of glucocorticoid receptor with a novel steroid receptor coactivator, Hic-5, which localizes to both focal adhesions and the nuclear matrix |
Q30407781 | Interactions between E6, FAK, and GIT1 at paxillin LD4 are necessary for transformation by bovine papillomavirus 1 E6 |
Q35618697 | Lepidopteran DALP, and its mammalian ortholog HIC-5, function as negative regulators of muscle differentiation |
Q24308733 | Leupaxin, a novel coactivator of the androgen receptor, is expressed in prostate cancer and plays a role in adhesion and invasion of prostate carcinoma cells |
Q38072352 | Markers of Cellular Senescence |
Q34073807 | Negative regulation of NADPH oxidase 4 by hydrogen peroxide-inducible clone 5 (Hic-5) protein |
Q33848114 | Paxillin and hydrogen peroxide-inducible clone 5 expression and distribution in control and Alzheimer disease hippocampi |
Q41732335 | Paxillin binding to a conserved sequence motif in the alpha 4 integrin cytoplasmic domain |
Q32054423 | Recruitment of the LIM protein hic-5 to focal contacts of human platelets |
Q24309482 | Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55 |
Q38316038 | Specific decrease in the level of Hic-5, a focal adhesion protein, during immortalization of mouse embryonic fibroblasts, and its association with focal adhesion kinase |
Q88978779 | TUG1 alleviates hypoxia injury by targeting miR-124 in H9c2 cells |
Q90481816 | The Leptin induced Hic-5 expression and actin puncta formation by the FAK/Src-dependent pathway in MCF10A mammary epithelial cells |
Q24291361 | The TES gene at 7q31.1 is methylated in tumours and encodes a novel growth-suppressing LIM domain protein |
Q24304470 | The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter |
Q40688193 | Transcriptional activation of the c-fos gene by a LIM protein, Hic-5. |
Q46719817 | Tyrosine-phosphorylated Hic-5 inhibits epidermal growth factor-induced lamellipodia formation |
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