Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines

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Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1025213070
P356DOI10.1007/S12079-009-0080-4
P932PMC publication ID2821476
P698PubMed publication ID19898959
P5875ResearchGate publication ID38075858

P50authorLester F LauQ82746733
P2093author name stringChih-Chiun Chen
P2860cites workFas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivoQ24315092
Riboflavin kinase couples TNF receptor 1 to NADPH oxidaseQ24318509
Functions and mechanisms of action of CCN matricellular proteinsQ24642303
Matrix protein CCN1 is critical for prostate carcinoma cell proliferation and TRAIL-induced apoptosisQ24647641
The CCN family of proteins: structure-function relationshipsQ24658424
Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1Q24672489
The matrix protein CCN1 (CYR61) induces apoptosis in fibroblastsQ24678308
Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signalingQ24682392
The TNF and TNF receptor superfamilies: integrating mammalian biologyQ28203717
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatasesQ28239642
All in the CCN family: essential matricellular signaling modulators emerge from the bunkerQ28275856
Ethanol-induced apoptosis in mouse liver: Fas- and cytochrome c-mediated caspase-3 activation pathwayQ28343555
The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnoverQ28588830
Reversible oxidation and inactivation of protein tyrosine phosphatases in vivoQ29615579
Signalling pathways of the TNF superfamily: a double-edged swordQ29616428
Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinaseQ30175136
The CCN family of angiogenic regulators: the integrin connectionQ33545691
Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycansQ33902687
The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblastsQ33928429
Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release.Q34086292
Human tumour necrosis factor: physiological and pathological roles in placenta and endometriumQ34280666
Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin alphavbeta3.Q34454129
Tumor necrosis factor: an apoptosis JuNKie?Q35674085
Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transductionQ35918894
Regulation of the extrinsic apoptotic pathway by the extracellular matrix glycoprotein EMILIN2.Q36315249
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPasesQ36323820
Sphingolipid signaling and redox regulationQ36485442
Lethal effect of the anti-Fas antibody in miceQ36696599
Tumor necrosis factor (TNF) biology and cell deathQ36992543
Intervention for apoptosis in cardiomyopathyQ37031992
Extracellular matrix: a matter of life and death.Q37228574
Anoikis: a necessary death program for anchorage-dependent cellsQ37245449
Regulation of angiogenesis: apoptotic cues from the ECM.Q37302754
Targeted mutagenesis of the angiogenic protein CCN1 (CYR61). Selective inactivation of integrin alpha6beta1-heparan sulfate proteoglycan coreceptor-mediated cellular functionsQ38337503
The therapeutic effect of TNFR1-selective antagonistic mutant TNF-alpha in murine hepatitis modelsQ39936186
TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell deathQ40121624
Induction of tumor necrosis factor alpha production by human hepatocytes in chronic viral hepatitisQ41486203
Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.Q42048391
Expression of tumor necrosis factor-alpha and transforming growth factor-beta 1 in acute liver injuryQ45877712
Enhanced tumour necrosis factor and interleukin-1 in fulminant hepatic failureQ46733753
Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate.Q50704525
TNF-alpha-induced expression of adhesion molecules in the liver is under the control of TNFR1--relevance for concanavalin A-induced hepatitis.Q54024226
Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen SpeciesQ58419541
Increased plasma tumor necrosis factor in severe alcoholic hepatitisQ68785342
Role of Proinflammatory Cytokines in Acetaminophen HepatotoxicityQ71837634
TNF-alpha stimulation of fibroblast proliferation. Dependence on platelet-derived growth factor (PDGF) secretion and alteration of PDGF receptor expressionQ72240144
Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in miceQ74477596
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)63-69
P577publication date2009-11-07
P1433published inJournal of Cell Communication and SignalingQ26841964
P1476titleDeadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines
P478volume4

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cites work (P2860)
Q37708036Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis
Q33713723Apoptosis and angiogenesis: an evolving mechanism for fibrosis
Q46255850Bone marrow and adipose mesenchymal stem cells attenuate cardiac fibrosis induced by methotrexate in rats
Q46722317CCN1 sensitizes esophageal cancer cells to TRAIL-mediated apoptosis
Q34027926CCN1/CYR61: the very model of a modern matricellular protein.
Q28295283CCN2 is required for bleomycin‐induced skin fibrosis in mice
Q39755174CCN2/decorin interactions: a novel approach to combating fibrosis?
Q42274125CCN2: a bona fide target for anti-fibrotic drug intervention
Q42182664CCN3: the-pain-killer inside me.
Q26779818CCN: core regulatory proteins in the microenvironment that affect the metastasis of hepatocellular carcinoma?
Q89551749ColXV Aggravates Adipocyte Apoptosis by Facilitating Abnormal Extracellular Matrix Remodeling in Mice
Q36418892Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 gene
Q47111035Effect of ALDH2 on High Glucose-Induced Cardiac Fibroblast Oxidative Stress, Apoptosis, and Fibrosis
Q38651479Effects of CCN3 on rat cartilage endplate chondrocytes cultured under serum deprivation in vitro
Q54456353Extracellular matrix protein CCN1 regulates cardiomyocyte apoptosis in mice with stress-induced cardiac injury.
Q64233456Microvesicles containing miR-34a induce apoptosis of proximal tubular epithelial cells and participate in renal interstitial fibrosis
Q93007229Modulating Tumor Cell Functions by Tunable Nanopatterned Ligand Presentation
Q28582114NOV/CCN3 attenuates inflammatory pain through regulation of matrix metalloproteinases-2 and -9
Q53574472Regulation of CCN1 (Cyr61) in a porcine model of intestinal ischemia/reperfusion.
Q90216154Regulatory mechanism of NOV/CCN3 in the inflammation and apoptosis of lung epithelial alveolar cells upon lipopolysaccharide stimulation
Q34170764TNFα-induced apoptosis enabled by CCN1/CYR61: pathways of reactive oxygen species generation and cytochrome c release.
Q28254386Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets
Q47657800The fibrosis of ketamine, a noncompetitive N-methyl-d-aspartic acid receptor antagonist dose-dependent change in a ketamine-induced cystitis rat model
Q42175023The matricellular protein CCN1 regulates TNF-α induced vascular endothelial cell apoptosis.
Q39171928The matricellular protein CCN1 suppresses lung cancer cell growth by inducing senescence via the p53/p21 pathway
Q38180619The role of the CCN family of proteins in female reproduction

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