C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis

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C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis is …
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scholarly articleQ13442814

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P356DOI10.1105/TPC.106.045443
P953full work available at URLhttps://academic.oup.com/plcell/article-pdf/18/11/3275/36905967/plcell_v18_11_3275.pdf
P3181OpenCitations bibliographic resource ID2642107
P932PMC publication ID1693957
P698PubMed publication ID17138693
P5875ResearchGate publication ID6659632

P7228access restriction statusopen accessQ232932
P2093author name stringCsaba Koncz
Masaharu Mizutani
Takao Yokota
Kyomi Shibata
Kanzo Sakata
Marcel Lafos
Miklos Szekeres
Toshiyuki Ohnishi
Bunta Watanabe
Simona Bancos
Satomi Fujita
Anna-Maria Szatmari
P2860cites workArabidopsis CYP85A2, a cytochrome P450, mediates the Baeyer-Villiger oxidation of castasterone to brassinolide in brassinosteroid biosynthesisQ46604628
Arabidopsis CYP90B1 catalyses the early C-22 hydroxylation of C27, C28 and C29 sterolsQ46929754
Inactivation of brassinosteroid biological activity by a salicylate-inducible steroid sulfotransferase from Brassica napusQ47946474
The tomato Dwarf gene isolated by heterologous transposon tagging encodes the first member of a new cytochrome P450 family.Q48063804
A role for brassinosteroids in light-dependent development of ArabidopsisQ48064776
An Arabidopsis brassinosteroid-dependent mutant is blocked in cell elongation.Q52188855
Two independent and polarized processes of cell elongation regulate leaf blade expansion in Arabidopsis thaliana (L.) Heynh.Q52201906
CYP724B2 and CYP90B3 function in the early C-22 hydroxylation steps of brassinosteroid biosynthetic pathway in tomato.Q52672166
Biosynthesis of brassinosteroids in cultured cells of Catharanthus roseusQ73564020
The Arabidopsis deetiolated2 mutant is blocked early in brassinosteroid biosynthesisQ73945895
Two isoforms of NADPH:cytochrome P450 reductase in Arabidopsis thaliana. Gene structure, heterologous expression in insect cells, and differential regulationQ74118203
The DWF4 gene of Arabidopsis encodes a cytochrome P450 that mediates multiple 22alpha-hydroxylation steps in brassinosteroid biosynthesisQ74270688
Biosynthetic pathways of brassinolide in ArabidopsisQ74302617
Brassinosteroids do not undergo long-distance transport in pea. Implications for the regulation of endogenous brassinosteroid levelsQ80425792
Erect leaves caused by brassinosteroid deficiency increase biomass production and grain yield in riceQ82043720
Purification and Identification of New Acyl-conjugated Teasterones in Lily PollenQ104389983
Brassinosteroid-6-oxidases from Arabidopsis and tomato catalyze multiple C-6 oxidations in brassinosteroid biosynthesisQ28366681
The ROTUNDIFOLIA3 gene of Arabidopsis thaliana encodes a new member of the cytochrome P-450 family that is required for the regulated polar elongation of leaf cellsQ28776389
GENEVESTIGATOR. Arabidopsis microarray database and analysis toolboxQ33981484
The UGT73C5 of Arabidopsis thaliana glucosylates brassinosteroidsQ34084978
The tomato DWARF enzyme catalyses C-6 oxidation in brassinosteroid biosynthesis.Q35014597
The chemical characteristic and distribution of brassinosteroids in plantsQ35068098
Biosynthesis and metabolism of brassinosteroidsQ35540295
Metabolic channeling in plants.Q36051376
Metabolon formation and metabolic channeling in the biosynthesis of plant natural productsQ36110243
Rapid identification of Arabidopsis insertion mutants by non-radioactive detection of T-DNA tagged genesQ38361895
Brassinosteroids rescue the deficiency of CYP90, a cytochrome P450, controlling cell elongation and de-etiolation in Arabidopsis.Q42628760
Accumulation of 6-deoxocathasterone and 6-deoxocastasterone in Arabidopsis, pea and tomato is suggestive of common rate-limiting steps in brassinosteroid biosynthesisQ43623685
Regulation of transcript levels of the Arabidopsis cytochrome p450 genes involved in brassinosteroid biosynthesisQ44134008
An early C-22 oxidation branch in the brassinosteroid biosynthetic pathwayQ44177276
Isolation and characterization of a rice dwarf mutant with a defect in brassinosteroid biosynthesisQ44213628
Microarray analysis of brassinosteroid-regulated genes in ArabidopsisQ44213656
Loss-of-function of a rice brassinosteroid biosynthetic enzyme, C-6 oxidase, prevents the organized arrangement and polar elongation of cells in the leaves and stem.Q44224786
Organ-specific expression of brassinosteroid-biosynthetic genes and distribution of endogenous brassinosteroids in ArabidopsisQ44279342
A Rice Brassinosteroid-Deficient Mutant, ebisu dwarf (d2), Is Caused by a Loss of Function of a New Member of Cytochrome P450Q44654412
Arabidopsis CYP707As encode (+)-abscisic acid 8'-hydroxylase, a key enzyme in the oxidative catabolism of abscisic acidQ44830263
A putative role for the tomato genes DUMPY and CURL-3 in brassinosteroid biosynthesis and responseQ44872461
CYP90C1 and CYP90D1 are involved in different steps in the brassinosteroid biosynthesis pathway in Arabidopsis thaliana.Q45259128
A novel cytochrome P450 is implicated in brassinosteroid biosynthesis via the characterization of a rice dwarf mutant, dwarf11, with reduced seed lengthQ45261398
The last reaction producing brassinolide is catalyzed by cytochrome P-450s, CYP85A3 in tomato and CYP85A2 in ArabidopsisQ45264853
Patterns of Dwarf expression and brassinosteroid accumulation in tomato reveal the importance of brassinosteroid synthesis during fruit developmentQ46419596
Unique and overlapping expression patterns of Arabidopsis CYP85 genes involved in brassinosteroid C-6 oxidationQ46431099
Phenotypic and Genetic Analysis of det2, a New Mutant That Affects Light-Regulated Seedling Development in ArabidopsisQ46441391
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
Arabidopsis thalianaQ158695
brassinosteroidQ421976
(5S,8R,9S,10S,13S,17R)-17-[(2S,3R,4R,5S)-3,4-dihydroxy-5,6-dimethylheptan-2-yl]-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-oneQ105277891
(2S,3R,4R,5S)-2-[(3R,5S,8R,9S,10S,13S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-5,6-dimethylheptane-3,4-diolQ105309945
17-(3-Hydroxy-5,6-dimethylheptan-2-yl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-oneQ105327625
17-(3-hydroxy-5,6-dimethylheptan-2-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-olQ105376153
2-(3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-5,6-dimethylheptane-3,4-diolQ115948295
17-(3,4-Dihydroxy-5,6-dimethylheptan-2-yl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-oneQ115948399
3-dehydro-6-deoxoteasteroneQ27109342
6-deoxotyphasterolQ27109346
3-epi-6-deoxocathasteroneQ27126687
(5alpha,22S,24R)-22-hydroxyergostan-3-oneQ27126688
P6954online access statusopen accessQ232932
P304page(s)3275-88
P577publication date2006-11-01
P1433published inThe Plant CellQ3988745
P1476titleC-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis
P478volume18

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