The class 6 semaphorin SEMA6A is induced by interferon-gamma and defines an activation status of langerhans cells observed in pathological situations

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The class 6 semaphorin SEMA6A is induced by interferon-gamma and defines an activation status of langerhans cells observed in pathological situations is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2353/AJPATH.2006.050288
P932PMC publication ID1606484
P698PubMed publication ID16436660
P5875ResearchGate publication ID7336342

P50authorChristophe CauxQ56528905
Frederic GeissmannQ42599216
P2093author name stringElizabeth E M Bates
Jean-Jacques Pin
Pierre Garrone
Brigitte Sénéchal
Gregory Gautier
Blandine de Saint-Vis
P2860cites workAPCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motifQ22003753
Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebratesQ22010646
The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domainQ24290271
Biological activity of soluble CD100. II. Soluble CD100, similarly to H-SemaIII, inhibits immune cell migrationQ24290930
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Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiationQ24314914
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A poxvirus-encoded semaphorin induces cytokine production from monocytes and binds to a novel cellular semaphorin receptor, VESPRQ24316132
Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2Q24607154
The induction of tolerance by dendritic cells that have captured apoptotic cellsQ24671078
Dendritic cells and the control of immunityQ27860918
Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sitesQ42971765
Human semaphorin 6B [(HSA)SEMA6B], a novel human class 6 semaphorin gene: alternative splicing and all-trans-retinoic acid-dependent downregulation in glioblastoma cell lines.Q43605559
Human dendritic cells express neuronal Eph receptor tyrosine kinases: role of EphA2 in regulating adhesion to fibronectinQ44542251
Characterization of a novel member of murine semaphorin familyQ48097532
The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient miceQ49157483
Langerhans-cell histiocytosis 'insight into DC biology'.Q53380563
GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cellsQ59067424
Differentiation of Langerhans cells in Langerhans cell histiocytosisQ62658257
Reappearance of CD1a antigenic sites after endocytosis on human Langerhans cells evidenced by immunogoldrelabelingQ69949045
TGF-beta 1 promotes in vitro development of dendritic cells from CD34+ hemopoietic progenitorsQ71403490
Langerhans cell histiocytosisQ71870918
Interferon-gamma inhibits tumor antigen presentation by epidermal antigen-presenting cellsQ72469069
Coincident expression of the chemokine receptors CCR6 and CCR7 by pathologic Langerhans cells in Langerhans cell histiocytosisQ73139560
Respective involvement of TGF-beta and IL-4 in the development of Langerhans cells and non-Langerhans dendritic cells from CD34+ progenitorsQ73217948
CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alphaQ73672017
Functional soluble CD100/Sema4D released from activated lymphocytes: possible role in normal and pathologic immune responsesQ73919451
Unified nomenclature for the semaphorins/collapsins. Semaphorin Nomenclature CommitteeQ28137621
Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signalingQ28140151
Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responsesQ28189775
Immune semaphorins: a new area of semaphorin researchQ28191419
Biological activity of soluble CD100. I. The extracellular region of CD100 is released from the surface of T lymphocytes by regulated proteolysisQ28205197
Plasmacytoid dendritic cells: from specific surface markers to specific cellular functionsQ28217326
Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3betaQ28302521
Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamicsQ28590972
Identification of CD72 as a Lymphocyte Receptor for the Class IV Semaphorin CD100Q29036802
The molecular biology of axon guidanceQ29617857
Aromatic and basic residues within the EVH1 domain of VASP specify its interaction with proline-rich ligandsQ30175343
Shared resources between the neural and immune systems: semaphorins join the ranksQ33711432
Regulation of dendritic cell trafficking: a process that involves the participation of selective chemokinesQ33712280
Chemokines and cell migration in secondary lymphoid organsQ33807114
Signalling by semaphorin receptors: cell guidance and beyond.Q33994985
Dendritic cell biology and regulation of dendritic cell trafficking by chemokinesQ34129744
Identification, characterization, and functional study of the two novel human members of the semaphorin gene familyQ34137975
Sema7A is a potent monocyte stimulator.Q34145762
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2.Q34154039
Subtractive hybridization reveals the expression of immunoglobulin-like transcript 7, Eph-B1, granzyme B, and 3 novel transcripts in human plasmacytoid dendritic cellsQ34154814
Semaphorins in interactions between T cells and antigen-presenting cellsQ34174529
The CD100-CD72 interaction: a novel mechanism of immune regulationQ34460685
Regulation of dendritic cell recruitment by chemokinesQ34505316
Knowing how to navigate: mechanisms of semaphorin signaling in the nervous systemQ34528240
Controlling the immune system through semaphorinsQ34611960
Scatter-factor and semaphorin receptors: cell signalling for invasive growthQ34632043
Chemotropic Molecules: Guides for Axonal Pathfinding and Cell Migration During CNS DevelopmentQ35128796
CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alphaQ36367113
Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skinQ36376581
Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell toleranceQ36376611
A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cellsQ36377496
Chemokines, leukocyte trafficking, and inflammationQ40502969
IL-10 induces CCR6 expression during Langerhans cell development while IL-4 and IFN-gamma suppress it.Q40769871
Immunologic properties of purified epidermal Langerhans cells. Distinct requirements for stimulation of unprimed and sensitized T lymphocytesQ41819359
Transforming growth factor beta1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cellsQ41965708
Mobilizing dendritic cells for tolerance, priming, and chronic inflammationQ42576422
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)453-65
P577publication date2006-02-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleThe class 6 semaphorin SEMA6A is induced by interferon-gamma and defines an activation status of langerhans cells observed in pathological situations
P478volume168

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Q37367284Roles of semaphorins in the immune and hematopoietic system
Q35012897The semaphorins
Q37509059Transmembrane semaphorins: Multimodal signaling cues in development and cancer.

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