AIDS-associated Kaposi's sarcoma (KS) cells express oncostatin M (OM)-specific receptor but not leukemia inhibitory factor/OM receptor or interleukin-6 receptor. Complete block of OM-induced KS cell growth and OM binding by anti-gp130 antibodies

scientific article published on September 1, 1995

AIDS-associated Kaposi's sarcoma (KS) cells express oncostatin M (OM)-specific receptor but not leukemia inhibitory factor/OM receptor or interleukin-6 receptor. Complete block of OM-induced KS cell growth and OM binding by anti-gp130 antibodies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI118167
P8608Fatcat IDrelease_binyucvtfrfxncsy3mytnnx4uu
P953full work available at URLhttp://www.jci.org/articles/view/118167/files/pdf
https://europepmc.org/articles/PMC185754
https://europepmc.org/articles/PMC185754?pdf=render
P932PMC publication ID185754
P698PubMed publication ID7657807

P2093author name stringS. Nakamura
T. Kishimoto
T. Taga
K. Murakami-Mori
P2860cites workOncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cellsQ24305320
Neuropoietic cytokines in the hematopoietic foldQ24322963
Molecular cloning and expression of an IL-6 signal transducer, gp130Q24328945
Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6Q24337530
Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cellsQ24627585
Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin MQ24633689
Oncostatin M and leukemia inhibitory factor trigger overlapping and different signals through partially shared receptor complexesQ28250222
Identification and characterization of cellular receptors for the growth regulator, oncostatin MQ28251326
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130Q28279735
Identification of a major growth factor for AIDS-Kaposi's sarcoma cells as oncostatin MQ28284457
The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptorQ28284469
Regulation of IL-6 expression by oncostatin MQ28308106
LIGAND: A versatile computerized approach for characterization of ligand-binding systemsQ29547346
AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6Q33602539
The natural history of Kaposi's sarcoma in the acquired immunodeficiency syndromeQ34693731
Oncostatin M is a mitogen for rabbit vascular smooth muscle cellsQ36076266
Receptors for T cell-replacing factor/interleukin 5. Specificity, quantitation, and its implicationQ36355310
Oncostatin M, leukemia inhibitory factor, and interleukin 6 induce the proliferation of human plasmacytoma cells via the common signal transducer, gp130.Q36362934
Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130Q36362977
Functional inhibition of hematopoietic and neurotrophic cytokines by blocking the interleukin 6 signal transducer gp130Q37304521
Oncostatin-M stimulates tyrosine protein phosphorylation in parallel with the activation of p42MAPK/ERK-2 in Kaposi's cells. Evidence that this pathway is important in Kaposi cell growthQ40339285
Interactions between oncostatin M and the IL-6 signal transducer, gp130.Q41470736
Correlation of oncostatin M secretion by human retrovirus-infected cells with potent growth stimulation of cultured spindle cells from AIDS-Kaposi's sarcoma.Q41551727
Kaposi's sarcoma in organ transplant recipients: report of 20 casesQ41593468
Interleukin-6 signal transducer gp130 mediates oncostatin M signaling.Q41607790
Oncostatin M up-regulates low density lipoprotein receptors in HepG2 cells by a novel mechanism.Q41665039
Prevalence of Kaposi's sarcoma among patients with AIDS.Q44775763
Inhibition of development of Kaposi's sarcoma-related lesions by a bacterial cell wall complexQ46576000
Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACsQ46643016
Kaposi's sarcoma in AIDS. Multicentric angioneoplasia in early skin lesions.Q52255154
Kaposi's sarcoma cells: long-term culture with growth factor from retrovirus-infected CD4+ T cells.Q52833089
AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects.Q54565305
Angiogenic properties of Kaposi's sarcoma-derived cells after long-term culture in vitro.Q55242415
Recombinant oncostatin M stimulates the production of acute phase proteins in HepG2 cells and rat primary hepatocytes in vitroQ67895364
Purification and characterization of cytostatic lymphokines produced by activated human T lymphocytes. Synergistic antiproliferative activity of transforming growth factor beta 1, interferon-gamma, and oncostatin M for human melanoma cellsQ70363599
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
cell growthQ189159
Kaposi's sarcomaQ725345
antibodyQ79460
interleukin-6Q24724988
Gene expressionQ112947517
P304page(s)1319-27
P577publication date1995-09-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleAIDS-associated Kaposi's sarcoma (KS) cells express oncostatin M (OM)-specific receptor but not leukemia inhibitory factor/OM receptor or interleukin-6 receptor. Complete block of OM-induced KS cell growth and OM binding by anti-gp130 antibodies
P478volume96

Reverse relations

cites work (P2860)
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Q48506360Contradictory Concepts in the Etiology and Regression of Kaposi's Sarcoma. The Ferenc Györkey Memorial Lecture
Q42811240Cross-talk among gp130 cytokines in adipocytes
Q41474260Cytokines and the hepatic acute phase response
Q40815412Differential effects of oncostatin M and leukaemia inhibitory factor expression in astrocytoma cells.
Q24313382Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation
Q36897350Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 complex.
Q35746838Exclusive neutrophil recruitment with oncostatin M in a human system
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Q36437751Interleukin-4 receptor expression on AIDS-associated Kaposi's sarcoma cells and their targeting by a chimeric protein comprised of circularly permuted interleukin-4 and Pseudomonas exotoxin
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Q61641140Kaposi's sarcoma: a result of the interplay among inflammatory cytokines, angiogenic factors and viral agents
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Q73634638Oncostatin M and transforming growth factor-beta 1 induce post-translational modification and hyaluronan binding to CD44 in lung-derived epithelial tumor cells
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Q37373492Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow
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Q41387021The signal transducer gp130 is shared by interleukin-6 family of haematopoietic and neurotrophic cytokines
Q35917368Therapeutic options for human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus-related disorders

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