An ultrasensitive Ca2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling

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An ultrasensitive Ca2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2003PNAS..10010512B
P356DOI10.1073/PNAS.1932759100
P3181OpenCitations bibliographic resource ID2605511
P932PMC publication ID193592
P698PubMed publication ID12928489
P5875ResearchGate publication ID10604928

P2093author name stringJ Michael Bradshaw
Tobias Meyer
Howard Schulman
Yoshi Kubota
P2860cites workNeuronal CA2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular functionQ28202316
The molecular basis of CaMKII function in synaptic and behavioural memoryQ28216850
Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learningQ28260712
Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulationQ28575500
Cellular signaling through multifunctional Ca2+/calmodulin-dependent protein kinase II.Q34092385
Bistability in the Ca(2+)/calmodulin-dependent protein kinase-phosphatase systemQ34174169
A mechanism for the Hebb and the anti-Hebb processes underlying learning and memoryQ34324150
A model of synaptic memory: a CaMKII/PP1 switch that potentiates transmission by organizing an AMPA receptor anchoring assemblyQ34335470
How regulated protein translocation can produce switch-like responsesQ34485181
A fresh look at the role of CaMKII in hippocampal synaptic plasticity and memoryQ34561492
Molecular mechanisms of CaMKII activation in neuronal plasticityQ34671451
Protein phosphatase 1 regulation by inhibitors and targeting subunitsQ34699609
Postsynaptic signaling and plasticity mechanismsQ34979911
Complexity of calcium signaling in synaptic spinesQ35007342
Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor bindingQ36101145
Phosphorylation-dependent subcellular translocation of a Ca2+/calmodulin-dependent protein kinase produces an autonomous enzyme in Aplysia neuronsQ36211963
All-or-none potentiation at CA3-CA1 synapsesQ36480157
Sensitivity amplification in biochemical systemsQ40132581
A practical guide to the preparation of Ca2+ buffersQ40761762
Interaction with the NMDA receptor locks CaMKII in an active conformationQ40791785
Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiationQ41103770
Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputsQ41331128
Dual role of calmodulin in autophosphorylation of multifunctional CaM kinase may underlie decoding of calcium signalsQ41469189
Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depressionQ41661848
Molecular characterization of calmodulin trapping by calcium/calmodulin-dependent protein kinase II.Q43625436
The life cycle of Ca(2+) ions in dendritic spines.Q43879113
Transient versus asymptotic dynamics of CaM kinase II: possible roles of phosphatase.Q45987653
Chemical quenched flow kinetic studies indicate an intraholoenzyme autophosphorylation mechanism for Ca2+/calmodulin-dependent protein kinase II.Q46056425
Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP.Q47955993
Switching characteristics of a model for biochemical-reaction networks describing autophosphorylation versus dephosphorylation of Ca2+/calmodulin-dependent protein kinase II.Q48565318
Studies on the generation of Ca2+/calmodulin-independent activity of calmodulin-dependent protein kinase II by autophosphorylation. Autothiophosphorylation of the enzymeQ68240342
Sensitivity of CaM kinase II to the frequency of Ca2+ oscillationsQ74016176
P433issue18
P407language of work or nameEnglishQ1860
P304page(s)10512-7
P577publication date2003-09-02
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleAn ultrasensitive Ca2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling
P478volume100

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